Dysregulation of lipid metabolism is a commonly observed feature associated with metabolic syndrome and leads to the development of negative health outcomes such as obesity, diabetes mellitus, non‐alcoholic fatty liver disease, or atherosclerosis. Time‐restricted feeding/eating (TRF/TRE), an emerging dietary intervention, has been shown to promote pleiotropic health benefits including the alteration of diurnal expression of genes associated with lipid metabolism, as well as levels of lipid species. Although TRF likely induces a response in multiple organs leading to the modulation of (...) lipid metabolism, a majority of the studies related to TRF effects on lipids have focused only on individual tissues, and furthermore there is a lack of insight into potential underlying mechanisms. In this review, we summarize the current insights regarding TRF effects on lipid metabolism and the potential mechanisms in adipose tissue, liver, skeletal muscle, and heart, and conclude by outlining possible avenues for future exploration. (shrink)

Environmental ethicists have frequently criticized ancient Greek philosophy as anti-environmental for a view of philosophy that is counterproductive to environmental ethics and a view of the world that puts nature at the disposal of people. This provocative collection of original essays reexamines the views of nature and ecology found in the thought of Plato, Aristotle, the Stoics, and Plotinus. Recognizing that these thinkers were not confronted with the environmental degradation that threatens contemporary philosophers, the contributors to this book find that (...) the Greeks nevertheless provide an excellent foundation for a sound theory of environmentalism. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Omissions and Chronological ComplexitiesJyoti Mohan (bio)The stated purpose of Chinese and Indian Ways of Thinking in Early Modern European Philosophy: The Reception and the Exclusion by Selusi Ambrogio is "to examine the European understanding of China and India within the histories of philosophy from 1600 to 1744."1 Specifically, Ambrogio sets out to investigate the antecedents of the "othering" of non-Western philosophies. How far back did the notion go, (...) that non-Western philosophies were inferior? While Ambrogio often extends his argument to non-Western philosophies in general, in this monograph he examines only what he defines as "orientalist" philosophies—the philosophies of India and China. Since Ambrogio is investigating the histories of philosophy written in Europe, this choice makes sense: India and China were the two philosophical giants that most European philosophers needed to include in their works in order to claim to be universalist. No philosopher who wrote about world philosophies—and by extension no historian of philosophy—could ignore India and China, whether it was to dismiss the philosophies emanating from these geographic regions as inferior, or to extol them as proof that Europe was not the birthplace of "original thought."Ambrogio has chosen a time span from 1600 to 1744 c.e. to represent "the year 1600 … [,] the publication of Barbaricae philosophae antiquitatum by Otto van Heurn[,] and 1744[,] the year of the publication of the last book of the Historia critica by Jakob Brucker."2 Within the limits of this time [End Page 220] span, Ambrogio examines the work of several scholars who included Indian and Chinese philosophies in their "world histories of philosophies" and delineates three major historiographical trends. His rationale for ending his study with Brucker's work is that after this eighteenth-century opus, "Asians were usually excluded from the histories of philosophy."3 This time span seems puzzling to me. I know that most, if not all, of the authors Ambrogio cites had successors in their individual traditions well into the nineteenth century, if not the twentieth. While many histories of philosophy focused solely on the Western and classical traditions (as they did during the period under review by Ambrogio as well), the work of historians and scholars on Orientalist philosophies continued to multiply. To the extent that Ambrogio diligently studies his sources and constructs his argument, his work is commendable, but as a historian my questions for Ambrogio have to do with the underlying rationale for the time span he has chosen, and, by that extension, by the choices of his sources. Below I collect evidence that Asians continue to be included in the histories of philosophy past 1744, and in so doing suggest that this fact has an impact on his historiographical model.For instance, I would like to understand why, in his choice of sources, he has omitted all colonial works, especially since he engages with the argument that descriptions and understandings of Indian and Chinese philosophies were meditated through lenses of proselytization and of conquest. Granted, he is beginning with historians of philosophy, but as the eighteenth and nineteenth centuries progressed, historians also diversified their writings—as Ambrogio acknowledges—into histories of religion for instance. The connections between, and descriptions of, non-Western religions and philosophies were so muddled that it is impossible to separate them, save by attending to the titles of individual authors' works as being about religion or philosophy, respectively.The contents of such works are so closely related, at least in the Indian context, that contemporary historians, especially of the colonial period and of Indology, do not quibble over whether these works are about religion or philosophy. For instance, Paul Masson-Oursel wrote in 1923 that the development of Indian philosophy was integral to and proceeded alongside the development of religion.4 Systems of philosophical thought in India operated within larger systems of religious practice. Based on this model, Masson-Oursel describes the development of Indian philosophy as proceeding from the needs of religion. So, for example, he theorized that the mix of an Indo-Iranian religion and a pastoral, fire-worshipping people with an older indigenous Dravidian culture of agriculture, Goddess worship, and belief in amulets, spells, talismans, and other... (shrink)

The effect of recent experience on current behavior has been studied extensively in simple laboratory tasks. We explore the nature of sequential effects in the more naturalistic setting of automobile driving. Driving is a safety-critical task in which delayed response times may have severe consequences. Using a realistic driving simulator, we find significant sequential effects in pedal-press response times that depend on the history of recent stimuli and responses. Response times are slowed up to 100 ms in particular cases, a (...) delay that has dangerous practical consequences. Further, we observe a significant number of history-related pedal misapplications, which have recently been noted as a cause for concern in the automotive safety community. By anticipating these consequences of sequential context, driver assistance systems could mitigate the effects of performance degradations and thus critically improve driver safety. (shrink)

The author attempts here to sketch the beginnings of an adequate interpretation of Plato's treatment of the tall and the equal in the "Phaedo". The paper consists of seven sections (roman numerals). In I-II, he (a) argues that any attempt to solve the puzzle stated at "Phaedo" 102 bc within the parameters there set down would "eo ipso" be an attempted theory of relational statements; (b) formulates that puzzle; and (c) shows that Frege solved it by denying its presuppositions. In (...) IV the author proposes an interpretation of Plato's solution: that the "than y" in "x is taller than y" modifies the "is." In V-VI he shows how this theory fits in with and sheds light on other aspects of the theory of forms: the connection to Non-Contradiction, The doctrines of degrees of reality and of immanent characters. Finally in VII he shows that the puzzle of relational statements as formulated in the "Phaedo" need not extend to "equal." the paper also includes (iii) a discussion of H-N Castañeda's interpretation of Plato's theory. (shrink)

In Color for Philosophers C. L. Hardin argues that chromatic objectivism?a view which identifies colour with some or other property of objects?must be false. The upshot of Hardin's argument is this: there is, in fact, no principled correlation between physical properties and perceived colours. Since that correlation is a minimal condition for objectivism, objectivism is false. Mohan Matthen, who accepts Hardin's conclusion for what can be called "simple objectivism," takes it that an adaptationist theory of biological function applied to (...) colour is able to surmount the problems Hardin describes. It is Matthen's view that I am primarily concerned with in this paper. I will argue that it entails an overly simple view of adaptive value?as, perhaps, do all objectivist views. (shrink)

Most liberals agree that governments should protect certain basic liberties, such as freedom of speech, freedom of religion and freedom of the person. Liberals disagree, however, about whether free market rights should also be protected. By “free market rights,” we mean those rights typically associated with laissez-faire economic systems such as freedom of contract, a right to market returns, and claims to privately own the means of production.We do not use the phrase “economic liberties,” as Tomasi does, because it does (...) not distinguish between the “economic rights” defended by classical liberal and those defended by socialists. Those on the right often see such freedoms as core liberal commitments, while those on the left argue that an economic system should be organized to protect the interests of the less advantaged members of society. If free market rights should be protected, then most existing societies are unjust. These societies fail the liberal standard in the same ways as th .. (shrink)

This article challenges a reductive analysis of social practices by distinguishing five kinds of reason for following the rules of conventional practices. Depending on one’s preferred intellectual tradition, conventional practices enable coordination, facilitate cooperation, constitute activities, fulfil reciprocity, or specify abstract rights. Instead of being rival theories of social practices, these different models complement one another in a normative analysis of social practices. By distinguishing five kinds of reasons to follow conventional rules, this paper supports a more dynamic conventionalist analysis (...) of subjects like property, the law, professional obligation, civic responsibility, and culture. (shrink)

Philosophers now treat the relationship between Classical Mendelian Genetics and molecular biology as a paradigm of nonreduction and this example is playing an increasingly prominent role in debates about the reducibility of theories ranging from macrosocial science to folk psychology. Patricia Churchland (1986), for example, draws an analogy between the alleged elimination of the “causal mainstay” of classical genetics and her view that today’s psychological theory will be eliminated by neuroscience. Patricia Kitcher takes an autonomous rather than eliminativist view of (...) the reported nonreduction in genetics and reasons that psychology will retain a similar autonomy from lower level sciences (1980 and 1982). Although Churchland and Kitcher offer different interpretations of the apparent failure of molecular biology to reduce classical genetics, they agree that this failure will help illuminate theoretical relations between psychology and lower level sciences. The appearance of the Mendelian example along side the usual ones from physics and chemistry marks a turning point in philosophy of science. (shrink)

In The Tyranny of the Ideal, Gerald Gaus gives an extended argument on behalf of the “Open Society.” Instead of claiming that it is uniquely best from some privileged moral perspective, he argues for the Open Society by showing why it is acceptable to many perspectives. In this way, Gaus argues for a liberal market-based society in a way that treats deep diversity as a fundamental feature of social life. However, the argument falters at four important points. When taken together, (...) these four problems significantly limit the significance of Gaus’s conclusions. (shrink)

Matthen’s semantic theory of color is compared and contrasted with a variety of dispositionalism, to be called response-intentionalism (since it claims that color is a disposition to produce intentional states involving color-looks. First, it is argued that the two theories are not so far from each other; Matthen might be a closed dispositionalist, since he does stress the causal power of surfaces to produce color representations (signs). Next, the pragmatist component of his theory is addressed. Can usefulness unify color? It (...) seems that some degree of unity is required for a plurality of things to be treated as a group useful in a specifi c way: existence is prior to usefulness, not the other way around. Finally, the dispositionalism (including response-intentionalism) is defended against Mohan’s epistemological objection, according to which the dispositionalist cannot account for a priori nature of one’s knowledge of color looks; it is argued that it can,and that it can even use roughly the same means as semantic realism. (shrink)

This paper concerns the paraconsistent logic LPQ⊃,F and an application of it in the area of relational database theory. The notions of a relational database, a query applicable to a relational database, and a consistent answer to a query with respect to a possibly inconsistent relational database are considered from the perspective of this logic. This perspective enables among other things the definition of a consistent answer to a query with respect to a possibly inconsistent database without resort to database (...) repairs. In an earlier paper, LPQ⊃,F is presented with a sequent-style natural deduction proof system. In this paper, a sequent calculus proof system is presented instead because such proof systems are generally considered more suitable as the basis of proof search procedures than natural deduction proof systems and proof search procedures can serve as the core of algorithms for computing consistent answers to queries. (shrink)

Interdisciplinarity has seemingly become a paradigm for modern and meaningful research. Clearly, the interdisciplinary modus of deliberation enables to unfold relevant but quite different disciplinary perspectives to the reflection of broader scientific questions or societal problems. However, whether the comprehensive results of interdisciplinary reflection prove to be valid or to be acceptable in trans-disciplinary terms depends upon certain preconditions, which have to be fulfilled for securing scientific quality and social trust in advisory contexts. The present book is written by experts (...) and practitioners of interdisciplinary research and policy advice. It analyses topical and methodological approaches towards interdisciplinarity, starting with the current role of scientific research in society. The volume continues with contributions to the issues of knowledge and acting and to trans-disciplinary deliberation. The final conclusions address the scientific system as substantial actor itself as well as the relevant research and education politics. (shrink)

The biopolitics of empire : slavery and "the Muslim" -- The biopolitics of settlement : temporality, desire, and civilization -- Foucault and queer theory -- Society must be destroyed -- Queer terror -- Bibliography.

The first clear and precise statement of the axioms of qualitative probability was given by de Finetti ([1], Section 13). A more detailed treatment, based however on more complex axioms for conditional qualitative probability, was given later by Koopman [5]. De Finetti and Koopman derived a probability measure from a qualitative probability under the assumption that, for any integer n, there are n mutually exclusive, equally probable events. L. J. Savage [6] has shown that this strong assumption is unnecessary. More (...) precisely, he proves that if a qualitative probability is only fine and tight, then there is one and only one probability measure compatible with it. No property equivalent to countable additivity has been used as yet in the development of qualitative probability theory. However, since the concept of countable additivity is of such fundamental importance in measure theory, it is to be expected that an equivalent property would be of interest in qualitative probability theory, and that in particular it would simplify the proof of the existence of compatible probability measures. Such a property is introduced in this paper, under the name of monotone continuity. It is shown that, if a qualitative probability is atomless and monotonely continuous, then there is one and only one probability measure compatible with it, and this probability measure is countably additive. It is also proved that any fine and tight qualitative probability can be extended to a monotonely continuous qualitative probability, and therefore, contrary to what might be expected, there is no loss in generality if we consider only qualitative probabilities which are monotonely continuous. At the present time there is still a controversy over the interpretation which should be given to the word probability in the scientific and technical literature. Although the present writer subscribes to the opinion that this interpretation may be different in different contexts, in this paper we do not enter into this controversy. We simply remark that a qualitative probability, as a numerical one, may be interpreted either as an objective or as a subjective probability, and therefore the following axiomatic theory is compatible with both interpretations of probability. (shrink)

Nearly all Disney movies represent to people mere possibilities. One can conceive of scenarios with genies, wooden puppets coming to life, flying elephants, and mermaids. And there certainly seems to be no special problem in conceiving of a scenario where all the author's experiences are a mere dream induced by a Maleficent‐like evil genius. The problem in the present context is that the possibility of a dream‐inducing Maleficent‐like evil genius guarantees that how things appear would be no different, whether she (...) is dreaming or not. But maybe there is a difference: does it not appear to her that there is a difference between dreaming and wakefulness? The very fact that she is aware of such a distinction at all suggests the distinction is real. People prefer a real life over an experientially identical dream life, or even a more pleasurable dream life, because there is more to life than just experience. (shrink)

ABSTRACTThe known works of the medieval astronomer/astrologer Henry Bate include a set of planetary mean motion tables for the meridian of his Flemish hometown Mechelen. These tables survive in three manuscripts representing two significantly different recensions, but have never been examined for their principles of construction or underlying parameters. Such analysis reveals that Bate employed an unusual value for the length of the tropical year, which was probably derived by comparing ancient and contemporary observations of the vernal equinox. In addition, (...) there are clear signs that Bate kept revising his parameters for the mean motions of Venus and the three superior planets, none of which can be traced back to earlier sources. Together with some of Bate’s preserved statements, these findings support the conclusion that the Tabule Machlinenses were unique among the astronomical tables produced in medieval Latin Christendom for using independently derived parameters that were the result of new observations. Bate’s achievement connects him to a wider milieu of astronomers operating in late-thirteenth-century Paris, who put an increased emphasis on observation and the critical examination of received data. (shrink)

Although Sibawayh dealt with it in a scattered manner under different headings there have been different views on na't (adjective), which is gene-rally included in the tawabi group in Arabic syntax, and there have been debates around these views. Na't, which is categorized as a proper adjective and qualifies the meaning of man'ut (mawsuf), has different characteristics from the sentence elements that indicate the subject. Nahiv scholars have mostly divided na't into two parts: real and causal na't, and they have (...) formulated certain rules for these two parts in accordance with the structure of the Arabic language. Since na't and man'ut are accepted as nouns, the i'rab of na't is subject to men'ut. However, some examples in the Qur'an and some expressions used by the Arabs caused objections to the i'rab of na't being the same as men'ut. It is observed that these objected examples are the cases where men'ut is known and the exceptional cases of madih, zam and jarri jivar. It is also obligatory for the na't to conform to the man'ut in terms of ma'rifiyyah, nekiriyyah, custom and gender. While Sibawayh (d. 180/796) considered it qabh (ugly) for non-propositional words to be na't, scholars such as Ibn Hisham (d. 218/833), Ibn al-Ḥajib (d. 646/1249), and Abd ar-Rahman Jami (d. 898/1492) accepted that na't could be either propositional or non-propositional and cited many examples of na't in the case of non-propositional words. Scholars such as Ibn Jinni (d. 392/1002) and Ibn al-Hajib gave an explanation of the causative na't without naming it, scholars such as Ebu’l-Bekā al-Ukbari (d. 616/1219) analyzed the subject under the title of causative adjective or causative na't, and Halid b. Abdullah al-Azhari discussed it under the title of al-wasf al-majazi. The subject of our study is to examine the handling of na't, which is one of the sentence elements in the Arabic language, in the works written on the field, its parts, the dimension that affects the meaning and the controversial aspects. The aim of the research is to examine the rules that Sibawayh deals with in his al-Kitâb on na'ta and the objections of later Arab linguists to these rules, and to contribute to the field by revealing different views on the subject. (shrink)

Some of the methods for data collection in experimental psychology, as well as many of the inferences from observed behavior or image scanning, are based on the implicit premise that language use can be linked, via the meaning of words, to specific subjective states. Wittgenstein’s well known private language argument (PLA), however, calls into question the legitimacy of such inferences. According to a strong interpretation of PLA, all of the elements of a language must be publicly available. Thus the meaning (...) of words is not fixed by reference to our private experiences, and so data from subjective state claims indicates nothing about our subjective experiences. Application of PLA to psychological studies based on descriptions of the experience of orgasm offers support for the strong version of the conclusion of PLA. We show that PLA has deep implications for data collection methods and inferences in experimental psychology. In particular we critique two contemporary research projects in neuroscience: one studying the ability to remember emotionally loaded words and the other studying experience of attraction. Both of these projects attempt to link subjective experiences and thought processes to particular observable brain states. The research methods appeal to (implicit) inferences from linguistic usage to subjective states. Application of PLA will show that such inferences cannot be made because the meaning of a word is not determined by any subjective state of the speaker. (shrink)