Objective: Pulmonary complications could badly affect the recovery of neurological function and neurological prognosis of neurological critically ill patients. This study evaluated the effect of high-flow nasal cannula therapy on decreasing pulmonary complications in neurologically critically ill patients.Patients and Methods: The patients admitted to the intensive care unit with serious neurological disease and receiving oxygen therapy were retrospectively reviewed. Patients were divided into the HFNC group and the conventional oxygen therapy group. We analyzed the data within these two groups, including (...) patients’ baseline data, short-term outcomes of respiratory complications, general outcomes including hospital stay, ICU stay and mortality, and neurological functions. To analyze the relevant factors, we performed multivariable logistic regression analysis.Results: A total of 283 patients met the criteria, including 164 cases in the HFNC group and 119 cases in the COT group. The HFNC group had remarkably less mechanical ventilation requirement with lower phlegm viscosity. Even more, ICU stay and total hospital stay were significantly shortened in the HNFC group.Conclusion: HFNC decreased pulmonary complications in neurologically critically ill patients and improved recovery of neurological function and neurological prognosis. (shrink)

A core feature of drug-resistant epilepsy is hyperexcitability in the motor cortex, and low-frequency repetitive transcranial magnetic stimulation is a suitable treatment for seizures. However, the antiepileptic effect causing network reorganization has rarely been studied. Here, we assessed the impact of rTMS on functional network connectivity in resting functional networks and their relation to treatment response. Fourteen patients with medically intractable epilepsy received inhibitive rTMS with a figure-of-eight coil over the vertex for 10 days spread across two weeks. We designed (...) a 6-week follow-up phase divided into four time points to investigate FNC and rTMS-induced timing-dependent plasticity, such as seizure frequency and abnormal interictal discharges on electroencephalography. For psychiatric comorbidities, the Hamilton Depression Scale and the Hamilton Anxiety Scale were applied to measure depression and anxiety before and after rTMS. FNC was also compared to that of a cohort of 17 healthy control subjects. The after-effects of rTMS included all subjects that achieved the significant decrease rate of more than 50% in interictal epileptiform discharges and seizure frequency, 12 patients with the reduction rate above 50% compared to the baseline, as well as emotional improvements in depression and anxiety. In the analysis of RSNs, we found a higher synchronization between the sensorimotor network and posterior default-mode network in epileptic patients than in healthy controls. In contrast to pre-rTMS, the results demonstrated a weaker FNC between the anterior DMN and SMN after rTMS, while the FNC between the aDMN and dorsal attention network was greater. Importantly, the depressive score was anticorrelated with the FNC of the aDMN-SMN, which was markedly different in the good and bad response groups treated with rTMS. Based on the vertex suppression by rTMS, it is possible to achieve temporary clinical efficacy by modulating network reorganization in the DMN and SMN for patients with refractory epilepsy. (shrink)

This study examines whether customer firms’ unethical behavior distorts suppliers’ investment decisions. Using litigation and restatement to measure unethical behavior, we find that suppliers with customers engaged in frauds tend to invest more during the cheating period, compared to unaffected suppliers. In cross-sectional analyses, we examine the moderating effect of suppliers’ reliance on customer information and peer information. Results show that more industry peers’ voluntary disclosures and analyst coverage, lower sales volatility, and lower relationship-specific investments mitigate the distortion effect on (...) suppliers. Suppliers’ overinvestments caused by customers’ misreporting also lead to the suppliers’ inferior future performance and subsequent negative market reaction, and the severity of customers’ misreporting influences the magnitude of suppliers’ investment distortions. These results are robust in a dynamic difference-in-difference specification, an SEC enforcement sample, and a sample that excludes observations for suppliers and customers in the same industry. This paper contributes to the ethics literature by emphasizing the importance of creditable supply-chain information transfer to investment decisions and clarifying the nontrivial influence of principal customers in the supply-chain network. (shrink)

The conflict of administrative morality among civil servants at the grassroots level arises from the background of China’s long-standing traditional culture, and the current administrative system cannot keep up with the pace of economic development. In the process of grassroots management, due to the lag in the construction of administrative morality, the traditional official standard thinking, the imperfection of the current system, and the restriction of human nature, it is easy to cause the administrative moral conflict of the grassroots civil (...) servants in practice. This paper takes the interpersonal society as the research background, analyzes the influence of the interpersonal society on the environment, and studies the administrative ethics conflicts and governance issues of basic civil servants from the interpersonal background. In addition, this paper conducts a more detailed field investigation based on fuzzy cluster analysis, analyzes the manifestations and causes of the administrative moral conflict of grassroots civil servants in the context of human society from multiple perspectives and levels, and then proposes countermeasures to solve the administrative moral conflict. The administrative moral conflict and governance of grass-roots civil servants under the background of interpersonal relationship is of great positive significance for solving the administrative moral conflict and improving the service awareness and service level of grass-roots civil servants. (shrink)

Lifelong premature ejaculation (LPE) is a common male sexual dysfunction. Lack of active control for rapid ejaculation brought great distress to sexual harmony, and even fertility. Previous neurophysiology studies revealed an ejaculation-related control mechanism in the brain. However, it remains unclear whether this inhibitory network is altered in LPE patients. The present study investigated the central inhibitory network function of LPE patients by using stop signal task-related functional magnetic resonance imaging and resting-state functional connectivity analysis. The results showed no difference (...) in task-related behavioral performance or neural activation during response inhibition between LPE patients and controls. However, LPE patients showed a significantly different correlation pattern between the stop signal reaction time (SSRT) and left inferior frontal gyrus activation during successful inhibition, in which a typical negative correlation between SSRT and the activation was completely disappeared in patients. In addition, using the left inferior frontal gyrus as a seed, patients showed weaker functional connectivity between the seed and two areas (left dental nucleus and right frontal pole) compared with controls. These data suggest that LPE patients have an abnormal brain control network, which may contribute to the reduced central control of rapid ejaculation. This study provides new insights into the neural mechanism of LPE involving the central inhibitory network, which may offer an underlying intervention target for future treatment. (shrink)

Personality disorders are usually treated with face-to-face sessions and/or digital mental health services. Among many schools of therapies, schema therapy stands out because rather than simply targeting the symptoms of PD, it cordially targets the cause of PD and heals the early maladaptive schema, thus is exceptionally good at soothing emotional disturbances before enacting cognitive restructuring, resulting in long-term efficacy. However, according to Piaget’s genetic epistemology, the unmet needs lie in the fact that the schemata that determine the adaptive behavior (...) can only be formed in the interaction with the real world that the patient is living in and reconsolidated by the feedback from the object world upon the patient’s newly-formed behavior. Therefore, in order to reshape the patient’s schema modes to support adaptive behavior and regain emotional regulation capabilities of the healthy adult, one may have to reconstruct the object world surrounding the patient. Metaverse, the bestowed successor to the Internet with the cardinal feature of “the sense of full presence,” can become a powerful tool to reconstruct a new object world for the patient with the prescription of a psychotherapist, so as to transform the treatment techniques in schema therapy into the natural autobiographical experiences of patients in the new object world, thus gradually reshape the patient’s schema modes that can ultimately result in an adaptive, and more inclusive, interaction with the real world. This work describes the underlying theory, the mechanism, the process, and ethical considerations of such promising technology for the not-too-far future. (shrink)

People often feel that a period of time becomes longer when it is described in more detail or cut into more segments, which is known as the time unpacking effect. The current study aims to unveil how time unpacking manipulation impacts intertemporal decision making and whether the gain-loss valence of choices moderates such impacts. We recruited 87 college students and randomly assigned them to the experimental conditions to complete a series of intertemporal choice tasks. The subjective values of the delayed (...) choices were calculated for each participant and then analyzed. The results showed that participants perceived longer time delays and higher subjective values on the delayed gains in the time unpacking conditions than in the time packing conditions. These results suggest that time unpacking manipulation not only impacts time perception but also other factors, which in turn, influence the valuation of delayed outcomes and thereby intertemporal choices. The results are discussed in comparison to previous studies to highlight the complexity of the mechanism underlying the effect of time unpacking on intertemporal decision making. (shrink)

Patients’ trust in their physicians improves their health outcomes because of better compliance, more disclosure, stronger placebo effect, and more physicians’ trustworthy behaviors. Patients’ autonomy may also impact on health outcomes and is increasingly being emphasized in health care. However, despite the critical role of trust and autonomy, patients that naïvely trust their physicians may become overly dependent and lack the motivation to participate in medical care. In this article, we argue that increased trust does not necessarily imply decreased autonomy. (...) Furthermore, patients with high levels of trust and autonomy preferences are most likely to have the best health outcomes. We propose a framework for understanding simultaneous trust and autonomy preferences and for recognizing their interactive effects on health outcomes in the dynamic medical encounter. This framework argues that policy makers and health care providers should make efforts to foster not only patients’ trust but also their preferences for autonomy and thus gain the best position for achieving health-related goals. (shrink)

This study investigates whether firms with fraudulent financial reporting time their earnings announcements strategically and finds that fraudulent firms are more likely to disclose their earnings in the after-market hours during their fraud periods to postpone fraud detection. Cross-sectional tests show that firms with lower visibility are more likely to adopt and benefit from this timing strategy. In addition, fraudulent firms are found to time their conference calls strategically and package their earning news with forecasts to flood the market with (...) information and lower the fraud detection rate. Results also show that unethical managers may benefit from insider trading when their firms use a timing strategy to lower the detection rate. This study sheds light on a potential strategy that unethical managers may adopt to camouflage their fraudulent financial reporting. These results are robust to a variety of settings of samples and model specifications. (shrink)

There is increasing interest in the role played by testosterone in economic decision-making and social cognition. However, despite the growing body of findings in this field of research, no empirical study to date has tested whether testosterone modulates decision-making when an asymmetrically dominated decoy option is introduced in a choice set. Within a choice set that comprises two options, an asymmetrically dominated decoy option is a third option that, when introduced in the choice set, is much worse than one of (...) the existing options, but comparable to the other existing option. Introduction of a decoy option leads to a preference toward the dominating option (i.e., decoy effect). Healthy male participants (n = 63) received a single-dose of 150 mg testosterone gel in a double-blind, placebo-controlled, between-subjects design. At 180 min post-administration, participants took part in a decision-making task to elicit decoy effect. Results showed that participants in the testosterone group made less consistent choices and more target choices (i.e., decoy effect) than participants in the placebo group. These findings are interpreted in light of the dual-process theory and are in line with existing evidence suggesting that testosterone promotes more intuitive and automatic judgments in human decision-making. (shrink)

This paper addresses the adaptive asymptotic tracking control problem for nonlinear systems whose virtual control gains are unknown nonlinear functions of system states. Only in the first step, the Nussbaum gain technique is utilized to handle the uncertain virtual control gain. In the remaining steps, virtual control gains are dealt with by constructing novel control laws without the approximation of the uncertain nonlinear functions and external disturbances by neural networks or fuzzy logic. New adaptive laws are defined to compensate for (...) unknown virtual control gains, uncertain parameters, and external disturbances. Finally, an adaptive tracking controller is designed and applied to the control of a 3-order robot system, which guarantees the boundedness of all the signals in the closed-loop system and asymptotic stability of the tracking error. (shrink)

Despite considerable disruption of social order caused by the COVID-19 pandemic, it has also been said to contribute to positive psychological changes and influence on the perception of public life satisfaction. The present study aimed to explore the association between the COVID-19 related posttraumatic growth and life satisfaction and the mediating role of personal values. A two-wave longitudinal design was used. 226 self-quarantined Chinese college students completed post traumatic growth inventory, satisfaction with life scale, personal values questionnaire between February 2020 (...) and May 2021. Results showed that more than half of self-quarantined Chinese college students reported moderate to high levels of the COVID-19 related posttraumatic growth. A structural equation model revealed that COVID-19 related posttraumatic growth was positively associated to life satisfaction, and self-transcendence and self-enhancement values partially mediated this association. These findings shed light on whether and how pandemic-related posttraumatic growth influenced personal life satisfaction, supporting the outcome and process perspectives of posttraumatic growth as well as Schwartz’s value theory. Based on the findings, some positive psychology interventions, such as online rumination activities and mindfulness practice, were proposed to enhance self-quarantined college students’ posttraumatic growth and life satisfaction. (shrink)

van Els, Paul. "Yin en Yang" (Yin and Yang). In: Woordenboek filosofie (Dictionary of Philosophy), edited by Harry Willemsen and Peter de Wind, 617. Antwerpen & Apeldoorn: Garant, 2015.

Ethicists haven’t paid much attention recently to the Chinese complementarity of yin and yang. That complementarity can be updated to take into account and also form the basis for some of our contemporary ethical thinking. In my From Enlightenment to Receptivity, I argue that Western thought has overemphasized rational control/autonomy at the expense of the countervailing virtue of receptivity, and it turns out that the yin/yang complementarity can be profitably viewed as anticipating and clarifying a complementarity between receptivity (...) and rational control that recent developments in Western philosophical thought point us toward. But just as Western philosophy has overemphasized rational autonomy, Chinese thinking hasn’t sufficiently appreciated its importance. Both Chinese and Western thought need to seek a more even balance between autonomy/control and receptivity, but the idea of such balance comes more from yin and yang than from anything in previous Western philosophy. (shrink)

本书主要内容包括:初恋风云——数学教育主心骨的的百年寻觅之旅、践约时代——“现代数学教育方式”渐行渐的近、热题冷谈——数学教育焦点话题的哲学断想.

The existence of the Dao 道(the Way), according to the Yizhuan 易传 (the Commentary), is something intangible. The connotation of the Dao is the law of change caused by the interaction between yin and yang. The main functions of the Dao are "to change" and "to generate". The intangible refers to the law of change caused by the interaction between yin and yang, and the law is expressed by the divinatory symbolic system (卦爻符号, the trigrams or hexagrams). It (...) is through the unique permutation of yin and yang lines of a trigram or hexagram that the law of change is explained as a universal model uniting celestial, terrestrial and human laws. The symbolic system is used to express the universal nature of continual generation of life. (shrink)

We can gain standing or mana in the world through cooperation (yin mana) or through competition (yang mana). Drawing on both Maori and Daoist ideas, the way of yin mana is explored, whereby all parties can gain through new and meaningful participatory activities.

Diogenes, Ahead of Print. In the study of Chinese thought, the products of the Han dynasty have historically been identified as those most antithetical to Western rationalism. In many of these narratives, the commentarial tradition and systems of complementary yin and yang receive the most attention. The present work draws on Mawangdui texts, the writings of Dong Zhongshu, the Huainanzi, and ultimately Heshanggong’s Commentary on the Daodejing to complexify this view. Within these examples one discovers divergent philosophies of opposites (...) and yin and yang that confound the notion of a monolithic and solely holistic Han cosmology. Ultimately, this paper seeks to promote Heshanggong’s Commentary as an exemplar of Eastern Han Daoist yin-yang theory that subdivides these two principles into mode and substance. Such an interpretive move explains the commentary’s valorization of yin modes but not yin substances, and yang substances but not yang modes. Furthermore, this approach unveils new insights about the relationship of the Dao and Heaven, the history of Daoism, and the varieties of correlative cosmologies in the Han. (shrink)

Personal reflection on the failure of liberal religion and on religious and secular ideologies.

The Belmont Report’s distinction between research and the practice of accepted therapy has led various authors to suggest that these purportedly distinct activities should be governed by different ethical principles. We consider some of the ethical consequences of attempts to separate the two and conclude that separation fails along ontological, ethical, and epistemological dimensions. Clinical practice and clinical research, as with yin and yang, can be thought of as complementary forces interacting to form a dynamic system in which the (...) whole exceeds the sum of its parts. Just as effective clinical practice cannot exist without clinical research, meaningful clinical research requires the context of clinical practice. We defend this thesis by triangulation, that is, by outlining how multiple investigators have reached this conclusion on the basis of varied theoretical and applied approaches. More confidence can be placed in a result if different methods/viewpoints have led to that result. (shrink)

In the study of Chinese thought, the products of the Han dynasty have historically been identified as those most antithetical to Western rationalism. In many of these narratives, the commentarial t...

In the study of Chinese thought, the products of the Han dynasty have historically been identified as those most antithetical to Western rationalism. In many of these narratives, the commentarial t...