Objective: Pulmonary complications could badly affect the recovery of neurological function and neurological prognosis of neurological critically ill patients. This study evaluated the effect of high-flow nasal cannula therapy on decreasing pulmonary complications in neurologically critically ill patients.Patients and Methods: The patients admitted to the intensive care unit with serious neurological disease and receiving oxygen therapy were retrospectively reviewed. Patients were divided into the HFNC group and the conventional oxygen therapy group. We analyzed the data within these two groups, including (...) patients’ baseline data, short-term outcomes of respiratory complications, general outcomes including hospital stay, ICU stay and mortality, and neurological functions. To analyze the relevant factors, we performed multivariable logistic regression analysis.Results: A total of 283 patients met the criteria, including 164 cases in the HFNC group and 119 cases in the COT group. The HFNC group had remarkably less mechanical ventilation requirement with lower phlegm viscosity. Even more, ICU stay and total hospital stay were significantly shortened in the HNFC group.Conclusion: HFNC decreased pulmonary complications in neurologically critically ill patients and improved recovery of neurological function and neurological prognosis. (shrink)

Reductionism about testimony has become less popular as philosophers have uncovered our epistemic dependence on others. Meanwhile, both non-reductionism and the interpersonal view face a challenge from gullibility. Surprisingly, the concept of gullibility has not been sustainedly examined. The primary goal in this paper is to propose an analysis of gullibility. After some introductory remarks, we begin this paper by discussing an account of gullibility in terms of insensitivity to defeaters. We argue that this account cannot accommodate cases where agents (...) are gullible. We, therefore, offer a dispositional account of gullibility. In so doing, we show how gullibility differs from other epistemic vices vis-à-vis its interpersonal features. We also discuss how treating gullibility as an intellectual vice has salient implications for the debate between reductionists and non-reductionists about gullibility. (shrink)