Introduction: Motor evoked potentials (MEPs) to transcranial magnetic stimulation are known to be susceptible to several sources of variability. However, conflicting evidences on individual characteristics in relatively small sample sizes have been reported. We investigated the effect of age, height, and sex on MEPs of the motor cortex and spinal roots in a large cohort. Methods: A total of 587 subjects clinically and neuroradiologically intact were included. MEPs were recorded during mild tonic contraction through a circular coil applied over the (...) “hot spot” of the first dorsal interosseous and tibialis anterior muscles, bilaterally. Central motor conduction time (CMCT) was estimated as the difference between MEP cortical latency and the peripheral motor conduction time by cervical or lumbar magnetic stimulation. Peak-to-peak MEP amplitude to cortical stimulation and right-to-left difference of each parameter were also measured. Results: After Bonferroni correction, general linear (multiple) regression analysis showed that both MEP cortical latency and peripheral motor conduction time at four limbs positively correlated with age and height. At lower limbs, an independent effect of sex on the same measures was also observed (with females showing smaller values than males). CMCT correlated with both age (negatively) and height (positively) when analyzed by a single regression; however, with a multiple regression analysis this significance disappeared, due to the correction for the multicollinearity within the dataset. Conclusions: Physical individual features need to be considered for a more accurate and meaningful MEPs interpretation. Both in clinical practice and in research setting, patients and controls should be matched for age, height, and sex. (shrink)

If our sense of the past is inevitably shaped by the explanatory logic of narrative, then the stories that we create in turn reveal the inescapable presence and ...

"Ne croyez surtout pas qu'il s'agisse de science-fiction : 18 avril 2015, une équipe de généticiens chinois entreprenait d'"améliorer" le génome de quatre-vingt-trois embryons humains. Jusqu'où ira-t-on dans cette voie? Sera-t-il possible un jour (bientôt? déjà?) d'"augmenter" à volonté tel ou tel trait de caractère de ses enfants, d'éradiquer dans l'embryon les maladies génétiques, voire d'enrayer la vieillesse et la mort en façonnant une nouvelle espèce d'humains "augmentés"? Nous n'en sommes pas (tout à fait) là, mais de nombreux centres de (...) recherche "transhumanistes" y travaillent partout dans le monde, avec des financements colossaux en provenance de géants du Web tel Google. Les progrès des technosciences sont d'une rapidité inimaginable, ils échappent encore à toute régulation. En parallèle, cette "infrastructure du monde" qu'est le Web a permis l'apparition d'une économie dite "collaborative", celle que symbolisent des applications comme Uber, Airbnb ou BlaBlaCar. Selon l'idéologue Jeremy Rifkin, elles annoncent la fin du capitalisme au profit d'un monde de gratuité et de souci de l'autre. N'est-ce pas, tout à l'inverse, vers un hyperlibéralisme, vénal et dérégulateur, que nous nous dirigeons? Certaines perspectives ouvertes par les innovations technoscientifiques sont enthousiasmantes, d'autres effrayantes. Ce livre cherche d'abord à les faire comprendre, et à réhabiliter l'idéal philosophique de la régulation, une notion désormais vitale, tant du côté de la médecine que de l'économie.". (shrink)

The doctor patient relationship starts with a story. Doctors' notes, a patient's chart, the recommendations of ethics committees and insurance justifications all hinge on written and verbal narrative interaction. The "practice" of narrative profoundly affects decision making, patient health and treatment and the everyday practice of medicine. In this edited collection, the contributors provide conceptual foundations, practical guidelines and theoretical considerations central to the practice of narrative ethics.

"Par dizaines, des expressions issues de la mythologie grecque se sont inscrites dans le langage courant : une "pomme de discorde", un "dédale de rues", prendre le "taureau par les cornes", toucher le "pactole", "tomber de Charybde en Scylla", suivre un "fil d'Ariane", "jouer les Cassandre", etc. Mille références endormies aux Sirènes, à Typhon, Océan, Triton, Python, Sibylle, Stentor, Mentor, Laïus, Argus, OEdipe et à tant d'autres personnages mythiques habitent encore incognito nos conversations de tous les jours. Je vous propose (...) de les réveiller en racontant les histoires magnifiques qui en sont l'origine. Mais il y a plus. Les grands mythes ne se limitent pas à des "contes et légendes". Ils proposent des leçons de vie et de sagesse d'une profondeur abyssale. La mythologie représente ainsi une tentative grandiose pour apporter des réponses à l'antique question métaphysique de "la vie bonne pour les mortels". Son étude, passionnante en elle-même, constitue pour cette raison une excellente introduction à la philosophie." Luc Ferry. (shrink)

Ces dernières années, la philosophie politique a trouvé un second souffle. Depuis la parution de la Théorie de la justice, au début des années 1970, et sous le double mouvement du déclin des idéologies et de l'écroulement du système communiste, de nouveaux débats sont apparus. Comment combiner le respect des droits individuels et le maintien d'une ambition collective? Comment intégrer au libéralisme politique un projet communautaire? Quelles doivent être les relations entre l'individu, l'Etat et la société? Comment répondre au malaise (...) et au déficit de légitimité que connaissent les démocraties occidentales? Ces interrogations ont permis d'imposer des voix nouvelles - celles de John Rawls ou de Jürgen Habermas -, mais aussi, plus récemment, celles des auteurs dits " communautariens " : Michaël Sandel, Michaël Walzer et Charles Taylor. Ces discussions sont également l'occasion d'en revenir aux fondateurs de la pensée politique contemporaine et de vérifier ainsi l'actualité de la réflexion d'Emmanuel Kant, de Friedrich Hegel, de Karl Marx, d'Alexis de Tocqueville, de John Stuart Mill ou, plus près de nous, de Sigmund Freud et de Max Weber pour penser les problèmes politiques et spirituels de notre temps. Cet ouvrage aimerait donner un aperçu des problématiques actuelles de la théorie politique. Pour la sélection des auteurs étudiés, la question de la liberté a servi de fil conducteur. (shrink)

Across two studies, a wide age range of participants was interviewed about the nature of death. All participants were living in rural Madagascar in a community where ancestral beliefs and practices are widespread. In Study 1, children (8–17 years) and adults (19–71 years) were asked whether bodily and mental processes continue after death. The death in question was presented in the context of a narrative that focused either on the corpse or on the ancestral practices associated with the afterlife. Participants (...) aged 8 years and older claimed that death brings an end to most bodily and mental processes. Nevertheless, particularly in the context of the religious narrative, they claimed that certain mental processes continue even after death. This assertion of an afterlife was more evident among adults than children, especially with respect to cognitive processes, such as knowing and remembering. In Study 2, 5‐ and 7‐year‐olds were asked similar questions in connection with the death of a bird and a person. Seven‐year‐olds consistently claimed that bodily and mental processes cease at death, whereas 5‐year‐olds were unsystematic in their replies. Together, the two studies replicate and extend findings obtained with Western children showing that, in the course of development, different conceptions of death are elaborated—a biological conception in which death terminates living processes and a religious conception in which death marks the beginning of a new form of spiritual existence. (shrink)

What happens when the meaning of life based on a divine revelation no longer makes sense? Does the quest for transcendence end in the pursuit of material success and self-absorption? Luc Ferry argues that modernity and the emergence of secular humanism in Europe since the eighteenth century have not killed the search for meaning and the sacred, or even the idea of God, but rather have transformed both through a dual process: the humanization of the divine and the divinization of (...) the human. Ferry sees evidence for the first of these in the Catholic Church's attempts to counter the growing rejection of dogmatism and to translate the religious tradition into contemporary language. The second he traces to the birth of modern love and humanitarianism, both of which demand a concern for others and even self-sacrifice in defense of values that transcend life itself. Ferry concludes with a powerful statement in favor of what he calls "transcendental humanism"--a concept that for the first time in human history gives us access to a genuine spirituality rooted in human beings instead of the divine. (shrink)

The purpose of this study was to illuminate the ethically difficult situations experienced by care providers working in a nursing home. Individual interviews using a narrative approach were conducted. A phenomenological-hermeneutic method developed for researching life experience was applied in the analysis. The findings showed that care providers experience ethical challenges in their everyday work. The informants in this study found the balance between the ideal, autonomy and dignity to be a daily problem. They defined the culture they work in (...) as not supportive. They also thought they were not being seen and heard in situations where they disagree with the basic values of the organization. The results are discussed in terms of Habermas’s understanding of modern society. Care settings for elderly people obviously present ethical challenges, particularly in the case of those suffering from dementia. The care provider participants in this study expressed frustration and feelings of powerlessness. It is possible to understand their experiences in terms of Habermas’s theory of modern society and the concept of the system’s colonization of the life world. (shrink)

Quand on a renoncé à démontrer l'existence de Dieu ou l'immortalité de l'âme, est-il encore rationnel de postuler que Dieu existe ou que l'âme est immortelle? Peut-on croire rationnellement dans l'incertitude la plus totale? Jean-Marc Ferry montre précisément en quoi la religion réflexive le permet. Celui qui s'y engage ne se prévaut d'aucun accès privilégié à la vérité. Au départ, cet engagement procède moins d'une croyance que d'une résolution. Il s'agit, en effet, d'un acte de pure liberté, dépourvu d'assise, acte (...) risqué qui fait que l'on accorde ou non sa confiance au réel. Ensuite seulement, entre l'athée et le croyant, les expériences pourront être confrontées ; et c'est quand l'un et l'autre assument pleinement leur absolue ignorance métaphysique que raison et religion peuvent enfin être conciliées. (shrink)

v. 1. Piaget's genetic epistemology, 1965-1980.--v. 2. Critique of Piaget's genetic epistemology, 1965-1980.

Steblin's fully updated reference focuses on musical key characteristics during the baroque, classical, and romantic periods. (Music).

Narration ou argumentation? Une nouvelle polarité philosophique se dessine ainsi, chargée d'enjeux relatifs à la question de l'éthique. Par la mise en récit des expériences, la narration confère à l'identité personnelle un ancrage et une épaisseur historiques, orientant l'éthique vers un idéal substantiel de vie bonne. Par la justification rationnelle des réclamations, l'argumentation engage la responsabilité des sujets de droit, infléchissant l'éthique vers une idée procédurale de la société juste. Mais comment articuler la visée substantielle à la voie procédurale? Comment (...) assurer, sur la voie du discours, le principe de reconnaissance? Dans cette entreprise, l'éthique de la reconstruction revêt une signification décisive. C'est à introduire ce concept original que sont consacrées ces réflexions. L'auteur suit en cela une exhortation de Paul Ricoeur à qui cet essai est dédié. (shrink)

Anthropology combines two quite different enterprises: the ethnographic study of particular people in particular places and the theorizing about the human species. As such, anthropology is part of cognitive science in that it contributes to the unitary theoretical aim of understanding and explaining the behavior of the animal species Homo sapiens. This article draws on our own research experience to illustrate that cooperation between anthropology and the other sub-disciplines of cognitive science is possible and fruitful, but it must proceed from (...) the recognition of anthropology’s unique epistemology and methodology. (shrink)

From the timeless wisdom of ancient Greece through to Christianity, the Enlightenment, existentialism and postmodernism, A Brief History of Thought brilliantly and accessibly explains the enduring teachings of philosophy - including its profound relevance in today's world as well as its essential role in achieving happiness and living a meaningful life. This lively journey through the great thinkers challenges every one of us to learn to think for ourselves and asks us the most important question of all: how can we (...) live better? (shrink)

For political and literary theorists working on race, Ralph Ellison’s Invisible Man is a canonical text. Most political theorists approach the novel through what this essay calls a “martyr reading,” though martyrdom is just one of several political strategies explored in the work. This essay highlights an alternative in Ellison’s repertoire. The “trickster reading” developed here better accounts for several key scenes in the novel and also shows the limits of martyrdom as a technique of democratic politics. While other democratic (...) theorists have identified Ellison with redemptive or deliberative aims, the novel’s references to Homer’s Odyssey, with its own trickster-hero, license a trickster reading of Invisible Man. Tricksters do not take on suffering, loss, or sacrifice in the hope of redemption nor are they necessarily committed to the virtues of deliberation. Instead, they evade sacrifice by resorting routinely to irony, cunning, and refusal. This reading demonstrates the importance of these techniques to Ellison’s vision and to our politics today. (shrink)

One of the many faces of Islam in Indonesia is the abangan Muslims or the abangans. As one of the most populous Muslim groups in the country, it is important to know them. To understand Indonesian Islam or Muslims, one cannot overlook them. The article argues that, amid recent escalating Muslim–Christian tension in the country, this majority Muslim group can play a significant role in enhancing Muslim–Christian relations in the future, on account of their worldview that emphasizes and maintains cosmic (...) harmony and balance of all existence. Their open and syncretic attitudes toward other religions may foster religious tolerance and coexistence. These are attested in the author’s personal engagement with them. It is suggested that Christians be more inclusive toward them, but, at the same time, be critical in engaging their worldview. These attitudes are necessary for building a mutual and peaceful Muslim–Christian relationship in the region. (shrink)

In written and spoken communications, metaphors are often used as an aid to help convey abstract or less tangible concepts. However, the benefits of using visual metaphors in visualization have so far been inconclusive. In this work, we report an empirical study to evaluate hypotheses that visual metaphors may aid memorization, visual search and concept comprehension. One major departure from previous metaphor-related experiments in the literature is that we make use of a dual-task methodology in our experiment. This design offers (...) an abstraction of typical situations where viewers do not have their full attention focused on visualization (e.g., in meetings and classes). The use of the secondary task introduces “divided attention”, and makes the effects of visual metaphors more observable. In addition, it also serves as additional masking in memory-based trials. The results of this study show that visual metaphors can help participants better remember the information depicted in visualization. On the other hand, visual metaphors can have a negative impact on the speed of visual search. The results also show a complex pattern as to the benefits of visual metaphors in helping participants grasp key concepts from visualization. (shrink)