The paper argues against the assumption that citizens of industrialized countries bear responsibility for greenhouse emissions in the nineteenth and early twentieth centuries. An array of arguments for such a historic responsibility is refuted. The crucial role of the assumption of a liability for bona fide misappropriation in a state of nature (Lockean strict liability) is pointed out.

Kant distinguishes sharply between a juridical and an ethical assessment of lies. For the latter, his Doctrine of Virtue establishes the immorality of maxims of lying. However, not all acts of lying have to result from maxims of lying. It will be shown that Kant’s conception of moral weakness extends to lies caused by fear. A morally weak person need not have an immoral character or lose her dignity. Therefore, the inhuman implications of Kant’s strict prohibition of lying can be (...) considerably mitigated if the possibility of fear-induced lies is taken into account. If a person follows the modern planner’s motto failure is not an option and excludes lies from her plans of action, she can satisfy the demands of Kant’s doctrine of virtue even if fear causes her to lie under some circumstances. (shrink)

This paper aims to show that there are certain basic structural similarities between modern decision theory and medieval approaches to decision making under conditions of incertitude. Modern decision theory as well as its medieval ancestor distinguish between two kinds of incertitude for which there are different decision rules. Modern decision theory distinguishes between risk and uncertainty, whereas in medieval decision theory, the balance or imbalance of a "scale of reasons" correspond to different kinds of incertitude. In the case of uncertainty (...) or a balance of reasons, both paradigms favor risk-avoidance, which is no coincidence since there is a demonstrable historical link between modern and medieval rules of risk-avoidance. (shrink)

Direct doxastic voluntarism claims that human beings can voluntarily decide what to believe in exactly the same way as they decide to raise an arm. Aquinas is often regarded as a proponent of this doctrine, which is widely rejected by modern philosophers. Modern defenders of Aquinas try to show that he in fact accepted a less problematic indirect doxastic voluntarism. However, some early modern scholastics ascribed more than an indirect doxastic voluntarism to Aquinas. The present article discusses these scholastic interpretations (...) and argues that Aquinas held a direct voluntarism of passing or suspending judgment on probable propositions in addition to an indirect doxastic voluntarism. None of these voluntarisms amount to a form of direct doxastic voluntarism in the modern sense. (shrink)

Das Ziel: Konstitutionssystem der Begriffe Das Ziel der vorliegenden Untersuchungen ist die Aufstellung eines erkenntnismäßig-logischen Systems der ...

In dieser Marburger Vorlesung aus dem Wintersemester 1924/25 stellt sich Heidegger die Aufgabe, Platons Spatdialog "Sophistes" im Ausgang von Aristoteles verstandlich zu machen. Zentrum des einleitenden Aristoteles-Teils ist die Folge der dianoethischen Tugenden im VI. Buch der "Nikomachischen Ethik", in der Heidegger die sich aufsteigernde Stufenfolge eines Entbergens erkennt und demgemass den Primat der "Physis" aus der Uberlegenheit ihres Entbergens begrundet. Damit legt Heidegger die Zusammengehorigkeit von Sein und Wahrheit als Horizont des aristotelisch-griechischen Philosophierens frei und gewinnt so den "Boden", (...) aus dem die platonische Seinsforschung, wie sie im "Sophistes" vorliegt, erwachsen ist. Dementsprechend stellt sich Heidegger im Hauptteil die Aufgabe, in fortlaufender Interpretation des "Sophistes" konkret zu zeigen, dass und wie Platons Ontologie aus dem Entbergen erwachsen ist. Die Vorlesung bezeugt, dass Heidegger die in seinem fruhen Hauptwerk "Sein und Zeit" gestellte Frage nach dem "Sinn von Sein", d.h. nach der Un-verborgenheit des Seins in der Auseinandersetzung mit der philosophischen Uberlieferung gewonnen hat. (shrink)

'My endeavour in these pages is to explain the main features of the method of philosophizing which we, the Vienna Circle, use, and by using try to develop further. It is the method of the logical analysis of science, or more precisely, of the syntactical analysis of scientific language.... The purpose of the book -- as of the lectures -- is to give a first impression of our method and of the direction of our questions and investigations to those who (...) are not yet acquainted with them.' -- From the Preface. (shrink)

Definition of the problem The present article focuses on the current international ethical debate on “responsible implementation” of expanded carrier screening to public healthcare systems. Expanded carrier screening is a novel genetic test which aims to provide information to couples about whether both partners carry a genetic variation for the same recessively inherited condition. It was introduced to the market by commercial laboratories in the U.S. in 2010; since about 2015, however, international debates have emerged on how and why to (...) offer the screening as a public health service. Arguments It is shown that, initially, enhancement of couples’ reproductive autonomy, not prevention of recessive disorders, has been established as the ethically well-founded aim and guiding principle of responsible implementation. Recently, however, in 2019, three well-known Dutch bioethicists argued that this aim has been embraced without much reflection and should therefore be replaced with the guiding principle of “responsible parenthood”. According to the latter, autonomous reproductive decision-making of couples or women is morally acceptable solely when carrier screening is done only during pregnancy. Before pregnancy, by contrast, couples are held to have a moral duty to take preventive measures if their future children are at risk of being affected by one of the “worst” recessive conditions. In the present paper, both of these conflicting ethical framings of expanded carrier screening are critically examined. Conclusions While the aim of reproductive autonomy also has problematic aspects, the notion of “responsible parenthood” is much more objectionable since it challenges voluntary participation in carrier screening, argues for directive genetic counseling, limits reproductive self-determination of women and couples, and introduces dubious concepts to the debate. (shrink)

The philosopher and historian of culture Wilhelm Dilthey (1833-1911) has had a significant and continuing influence on twentieth-century Continental philosophy and in a broad range of scholarly disciplines. Rudolf Makkreel interprets Dilthey's philosophy and provides a guide to its complex development. Against the tendency to divorce Dilthey's early psychological writings from his later hermeneutical and historical works, Makkreel argues for their essential continuity.

This “excellent translation” of Heidegger’s writings on Hegel shows an essential engagement between two of the foundational thinkers of phenomenology (Phenomenological Reviews). While Martin Heidegger’s writings on Hegel are notoriously difficult, this volume provides a clear and careful translation of two important texts—a treatise on negativity, and a penetrating reading of Hegel’s Phenomenology of Spirit. In these stimulating works, Heidegger relates his interpretation of Hegel to his own thought on the event, taking up themes developed in Contributions to Philosophy. While (...) many parts of the text are fragmentary in nature, these interpretations are considered some of the most significant as they bring Hegel into Heidegger’s philosophical trajectory. (shrink)

The cyclic GMP‐AMP synthase–stimulator of interferon genes (cGAS‐STING) pathway is central for the initiation of anti‐tumoural immune responses. Enormous effort has been made to optimise the design and administration of STING agonists to stimulate tumour immunogenicity. However, in certain contexts the cGAS‐STING axis fuels tumourigenesis. Here, we review recent findings on the regulation of cGAS expression and activity. We particularly focus our attention on the DNA‐dependent protein kinase (DNA‐PK) complex, that recently emerged as an activator of inflammatory responses in tumour (...) cells. We propose that stratification analyses on cGAS and DNA‐PK expression/activation status should be carried out to predict treatment efficacy. We herein also provide insights into non‐canonical functions borne by cGAS and cGAMP, highlighting how they may influence tumourigenesis. All these parameters should be taken into consideration concertedly to choose strategies aiming to effectively boost tumour immunogenicity. (shrink)

In der Arbeit wird eine textimmanente Problemstellung der Transzendentalen Dialektik der Kritik der reinen Vernunft aufgegriffen, indem ausgehend vom Grundsatz der Vernunft nach der Möglichkeit eines regulativen Apriori im Rahmen der methodischen Vorgaben der Kritik der reinen Vernunft gefragt wird. Kants regulativer Vernunftgebrauch wird in drei Teilen untersucht: Der erste Teil – Problemfeld – entwickelt ausgehend von der Antinomie der reinen Vernunft immanente Kriterien, durch die das Lehrstück des Anhangs zur Transzendentalen Dialektik dargestellt und geprüft werden kann. Der zweite Teil (...) – Analysen – entwickelt textimmanent die Herleitung der Vernunftbegriffe, das dadurch geleistete Systematische der Erkenntnis und ihre transzendentale Rechtfertigung. Der dritte Teil – Dimension und Reichweite – untersucht auf der Basis der textimmanenten Analyse die konkreten Beispiele, die Kant im Anhang zur Transzendentalen Dialektik anführt, um damit die begrifflich-abstrakten Gedankengänge an Fallbeispielen zu konkretisieren. Der Grundsatz der Vernunft wird dabei in seiner konstitutiven Form zurückgewiesen und in einer regulativen Interpretation als transzendentaler Grundsatz der Vernunft neu begründet. (shrink)

The purpose of this paper is to show that in Western postmodernism, both religion and the university are under the sign of simulacra. Friedrich Nietzsche’s “death of God” instigates a discussion of postmodernism and a simulacrum of religion. According to Jean Baudrillard and the theory of the Three Orders of the Simulacra, reality died and “hyperreality” took its place and now governs our existence. If, for Michel Foucault, the religious phenomenon today is outside theological beliefs and traditions, oriented towards the (...) body, power and panoptic supervision, for Jacques Derrida the phenomenon appears more as a negative theology of deconstruction. The theoretical objective seeks to explore the mutations that have occurred both in the academic environment and in religion under the phenomenon of globalisation and the technologisation of humanity. Here, the study of religion in universities is a third order simulacrum, the consequence of which is the illusion of knowledge and the unconditional independence of humanity, manipulated by technological evolution. The methodology used is Derridarian decon­struction, Nietzschean nihilism and the Baudrillardian criticism of the postmodern consumerist system. (shrink)

Excerpt from Über die Echtheit der Platonischen Briefe Der erste Aufenthalt Platos in Syrakus fällt, wie sich mit Hilfe einer bisher übersehenen Angabe seines Biographen Olympiodor feststellen läfst, in den Frühsommer des Jahres 388. Damals war Plato, der nach dem Zeugnis seines Schülers Hermodor 427 geboren ist, in der Tat beinahe 40 Jahre alt Das anfänglich gute Verhältnis zum älteren Dionys konnte bei der Ver schiedenheit der Charaktere nicht lange bestehen; schon um die Mitte des Sommers 388, zur Zeit der (...) olympischen Spiele, finden wir Plato wieder in Hellas. Nach einer bekannten Erzählung hatte nämlich der Tyrann den smrtanischen Gesandten Pullis veranlafst, ihn auf seinem Schiffe mitzunehmen und in Ägina aus Land zu setzen, damit er dort als Kriegsgefangener fest genommen und auf dem Sklavenmarkt verkauft würde. Es wäre nämlich gerade Krieg zwischen Athen und Ägina gewesen (bis Sein Gastfreund Anniceris von Cyrene sei zufällig hinzu gekommen und habe ihn losgekauft Ausdrücklich bemerkt Olympiodor zu dieser Erzählung, Anniceris sei mit einem Viergespann nach Hellas gekommen, um an den olympischen Spielen Demnach fällt Platos erste sizilische Reise in das Olympiadenjahr 388. Die chronologische Zuverlässigkeit des Briefes tritt am deutlichsten darin hervor, dafs nun seine An gabe, Plato sei damals beinahe 40 Jahre alt gewesen, gerade mit der bestbezeugten Angabe über sein Geburtsjahr übereinstimmt. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works. (shrink)

Technological augmentation in the field of communication is a new way of controlling and manipulating the interface between current political communications and information. This is because, within the new paradigms of power, political communication is under the influence of netocracy, a new and mythical form of cybertechnological superpanopticism. The general objective of this paper is to analyze the phenomenon of cybertechnological globalization where, according to Alexander Bard and Jan Söderqvist, this new form of political and communicative superpanopticism is the result (...) of netocracy. This is related not just to the undermining of capitalism, but also to the myth of internet transparency as the site for communicational freedom. In theoretical terms, this paper seeks to deconstruct this hypothesis based on Slavoj Žižek’s position on netocracy. He claims this phenomenon is little more than a new and perverse form of capitalism which engages new methods of manipulating political communication. The methodology used in this paper draws on Bard and Söderqvist’s arguments, Žižek’s critique and Gilles Deleuze’s deconstruction. (shrink)