This article offers a characterization of what I call multiple-models juxtaposition, a strategy for managing trade-offs among modeling desiderata. MMJ displays models of distinct phenomena to...

Background: Advocacy is an important role of psychiatric nurses because their patients are ethically, socially, and legally vulnerable. This study of Japanese expert psychiatric nurses’ judgments of interventions for patient advocacy will show effective strategies for ethical nursing practice and their relationship with Japanese culture. Objectives: This article explores Japanese psychiatric nurses’ decision to intervene as a patient advocate and examine their ethical, cultural, and social implications. Research design: Using semi-structured interviews verbatim, themes of the problems that required interventions were (...) inductively summarized by a qualitative analysis and their contexts and nursing judgments were examined. Participants and research context: The participants were 21 nurses with 5 or more years of experience in psychiatric nursing. Ethical considerations: The research was approved by Institutional Review Board of research site and study facilities. The participants gave written informed consent. Findings: Analysis of 45 cases showed that nurses decided to intervene when surrounding people’s opinions impeded patients’ safety, healthcare professionals’ policies impeded patients’ decision-making, own violent behaviors impeded treatment and welfare services for patients, own or families’ low acceptance of illness impeded patients’ self-actualization, inappropriate treatment or care impeded patients’ liberty, and their families abused patients’ property. Discussion: To solve conflicts between patients and their surrounding people, the nurses sought reconciliation between them, which is in accordance with Japanese cultural norms respecting harmony. When necessary, however, they protected patients’ rights against cultural norms. Therefore, their judgments cannot be explained by cultural norms alone. Conclusion: The findings indicate that the nurses’ judgments were based on respect for patients’ rights apart from cultural norms, and they first sought solutions fitting the cultural norms before other solutions. This seems to be an ethical, effective strategy if advocates know the culture in depth. (shrink)

This paper investigates the effects of group interaction in a storytelling situation for children using two robots: a reader robot and a listener robot as a side-participant. We developed a storytelling system that consists of a reader robot, a listener robot, a display, a gaze model, a depth sensor, and a human operator who responds and provides easily understandable answers to the children’s questions. We experimentally investigated the effects of using a listener robot and either one or two children during (...) a storytelling situation on the children’s preferences and their speech activities. Our experimental results showed that the children preferred storytelling with the listener robot. Although two children obviously produced more speech than one child, the listener robot discouraged the children’s speech regardless of whether one or two were listening. (shrink)

As I have pointed out in a series of papers, which appeared about fifteen years ago in the Revue de l'histoire des religions, there are numerous resemblances between the ancient myths of the Indo-Europeans, on the one hand, and those of Japan, on the other. These resemblances, relating both to the fundamental structures of the two mythological systems and to a number of curious details, constitute an assemblage which seems too conspicuous to be regarded as either accidental or the result (...) of a similitude of human mentalities, manifesting itself, so it seems, through the creation of a great many similar myths and legends throughout the length and breadth of the surface of our planet. (shrink)

Under certain conditions, the cell cycle can be arrested for a long period of time. Vertebrate oocytes are arrested at G2 phase, while somatic cells arrest at G0 phase. In both cells, nuclei have lost the ability to initiate DNA synthesis. In a pair of recently published papers,1,2 Méchali and colleagues and Coué and colleagues have clarified how frog oocytes prevent untimely DNA synthesis during the long G2 arrest. Intriguingly, they found only Cdc6 is responsible for the inability of immature (...) oocytes to replicate DNA. Cdc6 is a key component for replication licensing, and for G0 cells to re‐enter the proliferative stage. Strikingly similar strategies for preventing the untimely replication in both cells suggest that the suppression of replication licensing is a universal mechanism for securing the prolonged arrest of the cell cycle. BioEssays 25:313–316, 2003. © 2003 Wiley Periodicals, Inc. (shrink)

本書は、人間的営みとしての学びの広さ・深さ・自由さを確認していく。人間の成長、人間形成という視点から、学びの実践を通して「学び」の人間学的原理、学ぶ主体にとっての意味を考察。個人の具体的な経験を通して 、多様な学びのあり方を提示。日本人の学び方、教え方の伝統や特徴とその問題について考察。.

Research has documented the influence of ALS patients families’ attitudes on patients’ decision to accept or reject TIV, a treatment that in many cases will allow them to live long enough to experience locked-in syndrome ; under Japanese law the use of a ventilator cannot be terminated once it is essential to a patient’s survival, so to choose TIV means to choose the possibility of entering a locked-in state. Previous studies have not, however, elucidated the changes in family members’ attitudes (...) that take place after they receive pertinent information about the social systems and services available to them. This study aims to fill this gap by collecting and analyzing patients’ and family members’ narratives. In Japan, about 30% of ALS patients utilize TIV. This rate is much higher than in most other developed countries. Patients’ narratives illuminate the psychological and especially the contextual factors of their decision-making. Many Japanese patients who currently use a ventilator say that their family members encouraged them to prolong their lives through ventilation. These family members have done so because patients are able to use long-term ventilation for only ¥1000 per month, and can also access the latest communication devices and round the clock caregiver services in their homes at very low cost. Japanese caregivers who are supported by social systems and services including communication assistance, empowering factors such as patients’ associations, care provided by people outside the patient’s family, and a public nursing care system are able to encourage patients to decide to use longterm ventilation. (shrink)

In Book One of the Treatise of Human Nature, Hume seems to acknowledge the existence of both internal and external worlds, in which perceptions, objects, and bodies, exist. In particular, Hume seems directly to affirm the existence of extra-mental bodies, when he says at the beginning of the section "Of scepticism with regard to the senses," "We may well ask, What causes induce us to believe in theexistence of body? but 'tis in vain to ask, whether there be body or (...) not? That is a point, which we must take for granted in all our reasonings" (T 1.4.2.1; SBN 187).1 Furthermore, he thinks that the existence of body must be taken for granted because it is "an affair of too great importance to be trusted to our .. (shrink)

William James criticizes Hume for failing to adhere to the strictly empiricist method when he postulates discrete constituents of experience—which Hume calls perceptions—thereby making our experience a train of disconnected pieces. James argues that the discontinuity of experience in Hume results in part from his failure to recognize the immediate presence of relations in experience.1 Emphasizing a continuity and unity of experience, James thus differentiates his empiricism from Hume's as being radical in the sense that it recognizes relations as 'real' (...) parts of experience just as are things that are experienced to be so related.2 This raises a question concerning the experiential status of relations in Hume: is .. (shrink)

In A Treatise of Human Nature, Hume seems to use the term "object" to refer to different things in different contexts, including impressions, ideas, perceptions, and bodies. Does he ever use the term "external bodies" to refer to things in the extra-mental world? I argue that what Hume means by external bodies when he affirms their existence is not externally existing, material objects that are somehow presented to the mind or presented in impressions. Rather, the bodies that Hume affirms are, (...) at bottom, no different from perceptions, but they can be distinguished from merely internal perceptions like pain or pleasure in terms of their "different relations, connexions, and durations" (T 1.2.6.9; SBN 68). I conclude that in order to be consistent, given the various statements he makes throughout Book One of the Treatise, Hume must reject the philosopher's doctrine of double existence of perceptions and objects and affirm only the existence of perceptions, sometimes conceived as internally existing and mind-dependent and sometimes conceived as existing outside and independent of the mind. (shrink)

William James criticizes Hume for failing to adhere to the strictly empiricist method when he postulates discrete constituents of experience — which Hume calls perceptions — thereby making our experience a train of disconnected pieces. James argues that the discontinuity of experience in Hume results in part from his failure to recognize the immediate presence of relations in experience. Emphasizing a continuity and unity of experience, James thus differentiates his empiricism from Hume's as being radical in the sense that it (...) recognizes relations as ‘real’ parts of experience just as are things that are experienced to be so related. This raises a question concerning the experiential status of relations in Hume: is James correct in accusing Hume of failing to notice the experiential reality of relations? Does Hume deny the experiential reality of relations entirely? Or does Hume downplay the experiential reality of relations and come to take them merely as products of the imagination, hence not ‘real,’ for certain theoretical reasons? (shrink)

The literature on human and animal learning suggests that individuals attend to and act on cues differently based on the order in which they were learned. Recent studies have proposed that one specific type of learning outcome, the highlighting effect, can serve as a framework for understanding a number of early cognitive milestones. However, little is known how this learning effect itself emerges among children, whose memory and attention are much more limited compared to adults. Two experiments were conducted using (...) different versions of the general highlighting paradigm: Experiment 1 tested 3 to 6 year olds with a newly developed image-based version of the paradigm, which was designed specifically to test young children. Experiment 2 tested the validity of an image-based implementation of the highlighting paradigm with adult participants. The results from Experiment 1 provide evidence for the highlighting effect among children 3–6 years old, and they suggest age-related differences in dividing attention among multiple cues during learning. Experiment 2 replicated results from previous studies by showing robust biases for both image-based and text-based versions of the highlighting task. This study suggests that sensitivity to learning order emerges early through the process of cued attention, and the role of the highlighting effect in early language learning is discussed. (shrink)

In the Appendix to A Treatise of Human Nature, Hume famously retracts his account of personal identity by confessing that it involves a profound problem he cannot solve, which I have elsewhere identified and called the Bundling Problem. Neither of the two possible solutions that Hume himself considers in the Appendix is a viable option for him by his own lights, which might suggest that any successful account of a unified self must go beyond the empirical framework. In this paper, (...) I argue that we can find a strictly empiricist solution to Hume's problem in William James. I attempt to show that James's descriptions of our experience are phenomenologically more detailed and faithful to how experience is undergone from the first-person perspective, which allows him to explain our belief in an identical, unified self solely on empirical grounds. James finds unity and continuity right in the content of the stream of experience itself. A detailed investigation of James's accounts reveals that Hume's fundamental problem does not stem merely from his lack of empirical resources but, more importantly, from his tacit abandonment of the professed empiricist methodology. (shrink)

There are remarkable parallels between Hume and Nagarjuna in their denial of substantiality and independence in objects and their subsequent attitude toward our ordinary world. Acknowledging a deep-rooted human tendency to take objects as independent entities, they both argue that there is nothing intrinsic in those objects that make them unitary and independent, and that those characters are, strictly speaking, merely fictitious, mental constructs. They nonetheless affirm the existence of our ordinary world as real. Although their main purposes of the (...) philosophical inquiry are different (epistemological for Hume, and soteriological for Nagarjuna), their accounts of the nature of our world allow us to accept it in the way we ordinarily believe with the deeper understanding of it. It is only in this world where we think, act, and interact with others that an epistemology grounded in human sentiment and experience (for Hume) or humans liberation (for Nagarjuna) is possible. (shrink)

In 1997, the Japanese Diet revised the Bank of Japan law thereby granting the central bank greater independence in monetary policy making. The revision was an attempt by Japan's political class to weaken the authority of the powerful Ministry of Finance over the central bank and augment its own influence. The Bank of Japan, however, gained more autonomy than politicians ever intended, leading to frequent confrontations between the government and the central bank over monetary policy. This paper explores the new (...) strategic relationship that emerged between the Bank of Japan and government and the nature of monetary policy implemented in the post-reform period. We demonstrate that several factors contributed to the Bank's unexpected ability to enhance its independence: the astute leadership of the first post-reform governor Hayami Masaru; the Bank's ability to turn politicization of monetary policy to its advantage; and its pursuit of a strategy achieved by augmenting its own research capacity. On a theoretical level, our findings show that the passage of a new legal framework only marks the completion of one stage of institutional change and the start of the next; post-enactment politics have as much importance as pre-enactment politics in shaping outcomes. In the post-enactment phase, various factors, including the state of the economy and informal institutions or processes, matter greatly and may shift the direction of institutional change away from the intended path. (shrink)

This study aims to unveil the process of whistleblowing. Two nursing staff members who worked in a psychiatric hospital convicted of large-scale wrongdoing were interviewed. Data were analyzed using a modified grounded theory approach. Analysis of the interviews demonstrated that they did not decide to whistleblow when they were suspicious or had an awareness of wrongdoing. They continued to work, driven by appreciation, affection, and a sense of duty. Their decision to whistleblow was ultimately motivated by firm conviction. Shortly after (...) whistleblowing, wavering emotions were observed, consisting of a guilty conscience, fear of retribution, and pride, which subsequently transformed to stable emotions containing a sense of relief and regret for delayed action. It is necessary for nurses to recognize that their professional responsibility is primarily to patients, not to organizations. Nurses should also have professional judgment about appropriate allegiance and actions. (shrink)

Cyclic nucleotides can regulate the sensitivity of retinal rods to light through phosducin. The phosphorylation state of phosducin determines the amount of G available for activation by Rho*. Phosducin phosphorylation is regulated by cyclic nucleotides through their activation of cAMP-dependent protein kinase. The regulation of phosphodiesterase activity by the noncatalytic cGMP binding sites as well as Ca2+/calmodulin dependent regulation of cGMP binding to the cation channel are also discussed.

Facial expressions influence our experience and perception of emotions—they not only tell other people what we are feeling but also might tell us what to feel via sensory feedback. We conducted three experiments to investigate the interaction between facial feedback phenomena and different environmental stimuli, by asking participants to remember emotional autobiographical memories. Moreover, we examined how people with schizotypal traits would be affected by their experience of emotional facial simulations. We found that using a directed approach (gripping a pencil (...) with teeth/lips) while remembering a specific autobiographical memory could successfully evoke participants’ positive (e.g. happy and excited)/negative (e.g. angry and sad) emotions (i.e. Experiment 1). When using indirective environmental stimuli (e.g. teardrop glasses), the results of our experiments (i.e. Experiments 2 and 3) investigating facial feedback and the effect of teardrop glasses showed that participants who scored low in schizotypy reported little effect from wearing teardrop glasses, while those with high schizotypy reported a much greater effect in both between- and within-subject conditions. The results are discussed from the perspective of sense of ownership, which people with schizophrenia are believed to have deficits in. (shrink)