Functional electrical stimulation (FES), a method for inducing muscle contraction, has been successfully used in gait rehabilitation for patients with deficits after neurological disorders and several clinical studies have found that it can improve gait function after stroke and spinal cord injury. However, FES gait training is not suitable for patients with walking difficulty, such as those with severe motor paralysis of the lower limbs. We have previously shown that action observation combined with motor imagery (AO + MI) of walking (...) induces walking-related cortical activity. Therefore, we combined FES, which alternately generates dorsiflexion and plantar flexion, with AO + MI as an alternative to gait training. The present study investigates the transient effects of 20-min of FES simultaneously with and without AO + MI of walking on corticospinal and spinal reflex excitability in able-bodied participants. We measured motor evoked potentials and Hoffmann-reflexes to assess corticospinal and spinal reflex excitability at rest before and after the 20-min FES with and without the AO + MI. Our results show that FES without AO + MI did not change excitability (p > 0.05), while FES with AO + MI facilitated corticospinal excitability (p < 0.05). This facilitation likely occurred due to the synchronization of sensory inputs from FES and cortical activity during AO + MI. Facilitation was observed only in the dorsiflexor but not the plantar flexor muscle (p < 0.05), suggesting muscle specificity of the facilitation. These results demonstrate the effectiveness of combining FES with AO + MI and pave the way for novel neurorehabilitation strategies for patients with neurological gait deficits. (shrink)

BackgroundSocial cognitive impairments adversely affect social functioning in patients with schizophrenia. Although pharmacological interventions have been suggested to provide some benefits on social cognition, little information is available on the comparative efficacy of pharmacotherapy. Thus, the aim of this planned systematic review and network meta-analysis is to perform a quantitative comparison of the effects of various psychotropic drugs, including supplements, on social cognition disturbances of schizophrenia.MethodsThe literature search will be carried out using the PubMed, Embase, Cochrane Central Register of Controlled (...) Trials, PsycINFO, ClinicalTrials.gov, and International Clinical Trials Registry Platform databases from inception onward. Randomized controlled trials that examined the efficacy of drugs in social cognitive disturbances will be included, based on the most recent studies and the broader literature than previously searched. This protocol defines a priori the methods that will be used for study selection, data collection, quality assessment, and statistical syntheses.DiscussionThe findings this work are expected to help promote the development of better therapeutics of social cognitive impairments in schizophrenia and related psychiatric conditions.Systematic Review Registration[www.crd.york.ac.uk/prospero], identifier [CRD42021293224]. (shrink)

One of the central debates in the cognitive science of language has revolved around the nature of human linguistic competence. Whether syntactic competence should be characterized by abstract hierarchical structures or reduced to surface linear strings has been actively debated, but the nature of morphological competence has been insufficiently appreciated despite the parallel question in the cognitive science literature. In this paper, in order to investigate whether morphological competence should be characterized by abstract hierarchical structures, we conducted the crowdsourced acceptability (...) judgment experiment on morphologically complex words and evaluated five computational models of morphological competence against human acceptability judgments: Character Markov Models (Character), Syllable Markov Models (Syllable), Morpheme Markov Models (Morpheme), Hidden Markov Models (HMM), and Probabilistic Context-Free Grammars (PCFG). Our psycholinguistic experimentation and computational modeling demonstrated that "morphous" computational models with morpheme units outperformed "amorphous" computational models without morpheme units and, importantly, PCFG with hierarchical structures most accurately explained human acceptability judgments on several evaluation metrics, especially for morphologically complex words with nested morphological structures. Those results strongly suggest that human morphological competence should be characterized by abstract hierarchical structures internally generated by the grammar, not reduced to surface linear strings externally attested in large corpora. (shrink)

Hobbs (2010) introduced ‘clause-internal coherence’ (CIC) to describe inferences in, e.g., ‘A jogger was hit by a car,’ where the jogging is understood to have led to the car-hitting. Cohen & Kehler (2021) argue that well-known pragmatic tools cannot account for CIC, motivating an enrichment account familiar from discourse coherence research. An outstanding question is how to compositionally derive CIC from coherence relations. This paper takes strides in answering this question. It first provides experimental support for the existence of CIC (...) via offline evidence that attributive (non-)deverbal adjectives can trigger the same causal inferences within clauses that their predicative counterparts can trigger across clauses, albeit more weakly. To explain the experimental results, we use tools in Segmented Discourse Representation Theory (SDRT), which allows us to show that causal inferences can be derived in various ways, depending on whether deverbal adjectives are used attributively or predicatively. If the former, they are presupposition triggers and the coherence relations Elaboration/Continuation compete with Background; if the latter, Explanation/Result compete with Background. These different competitions -- cashed out in terms of interaction between default axioms -- correlate with the difference in the relative salience of the causal inferences. (shrink)

This paper examines the semantics and pragmatics of the Japanese causal connective mono. We show that the meaning of mono has three components: a causal relation, an emotive attitude toward the causing proposition, and an indication that the causal relation is of high quality. Further, we show that the latter two components are not at-issue content but expressive content. A formalization is provided in terms of the analysis of mixed content in McCready (2010). Finally, the proposal is briefly compared with (...) previous, informal, accounts of the meaning of mono. (shrink)

The purpose of this paper is phe-nomenological interpretation of the various faces of divinity in the later Heidegger and elucidation of the human comportment corresponding to this divinity. In the first chapter, I will make clear the relation between ontological difference in the sense of the later Heidegger and the primordial dimension of divinity which is called the last god and the sacred. Further, the relation between such divinity and entity as a whole will be clarified. In the second chapter, (...) I will elucidate the place of the divinities in the manifestation of entity as a whole by considering the role of the godlikes in the fourfold. When the primordial alterity of the last god should be experienced in entity as whole, which leads to the notion of the godlikes, it must confront human subject in totally asymmetrical manner. Such asymmetrical communication can be structurally made explicit by taking the concept of “discourse” in Being and Time into account. Finally, I will consider the character of human comportment called preservation with focusing on its relation to the later Heidegger’s conceptions of divinity. This will shed light on how human beings could properly appreciate the experience of what is beyond our understanding and nevertheless supporting our existence.El objetivo de la ponencia es llevar a cabo una interpretación fenomenológica de las diversas facetas de la divinidad en el Hei-degger tardío y elucidar el comportamiento humano respecto de esta divinidad. En el primer capítulo, se esclarece la relación entre la diferencia ontológica en el sentido que le da el segundo Heidegger y la dimensión primordial de la divinidad, llamada el último dios y lo sagrado. A conti-nuación, se esclarecerá la relación entre la divinidad así concebida y lo ente en totalidad. En el segundo apar-tado, se elucidará el lugar de las divinidades en la manifestación de lo ente en totalidad considerando el papel de los divinos la Cuaternidad. Cuando la alteridad primordial del último dios se experimente en lo ente en totaliadd, lo cual conduce a la noción de los divinos, tiene que enfrentarse al sujeto humano de una forma totalmente asimétrica. Esta comunicación asimétrica puede explicitarse estructuralmente mediante la consideración del concepto del discurso en Ser y tiempo. Final-mente, consideraré el carácter del comportamiento humano denominado la preservación, con especial atención a su relación con la noción de lo divino en Heidegger tardío. Esto arrojará luz sobre cómo los seres humanos podrían apreciar de manera adecuada lo que está más allá de nuestra comprensión y sin embargo, sostiene nuestra existencia. (shrink)

This paper describes the situation of philosophy in Japan with respect to the question of internationalism. For more than a hundred years, Japan took Western culture as its model and European philosophy as the authentic philosophy. This tendency was paradoxically strengthened by the post‐war humanism. It gave us Japanese philosophers a clear discipline to work in but cut us off from our own native culture, history, and philosophical traditions. In wishing to recover this loss, I argue that it is necessary (...) to distinguish between two forms of internationalism: humanistic and merely fashionable. The latter in fact derives from domestic reasons. (shrink)

Volume 20, Issue 8, August 2020, Page 32-36.

This article considers social choice theory without the Pareto principle. We revisit the trade-off theorem developed by Campbell and Kelly (Econometrica 61:1355–1365, 1993) and generalize their result. By introducing an alternative measure of decisive structure, a dominance relation, we show that if a social welfare function dominates another social welfare function, then the number of pairs of alternatives which social ranking is independently of individual preferences under the former is not more than that under the latter. Moreover, we offer two (...) applications of our main result. (shrink)

Are mechanisms for social attention influenced by culture? Evidence that social attention is triggered automatically by bottom-up gaze cues and is uninfluenced by top-down verbal instructions may suggest it operates in the same way everywhere. Yet considerations from evolutionary and cultural psychology suggest that specific aspects of one's cultural background may have consequence for the way mechanisms for social attention develop and operate. In more interdependent cultures, the scope of social attention may be broader, focusing on more individuals and relations (...) between those individuals. We administered a multi-gaze cueing task requiring participants to fixate a foreground face flanked by background faces and measured shifts in attention using eye tracking. For European Americans, gaze cueing did not depend on the direction of background gaze cues, suggesting foreground gaze alone drives automatic attention shifting; for East Asians, cueing patterns differed depending on whether the foreground cue matched or mismatched background cues, suggesting foreground and background gaze information were integrated. These results demonstrate that cultural background influences the social attention system by shifting it into a narrow or broad mode of operation and, importantly, provides evidence challenging the assumption that mechanisms underlying automatic social attention are necessarily rigid and impenetrable to culture. (shrink)

As humans, we constantly change our movement strategies to adapt to changes in physical functions and the external environment. We have to walk very slowly in situations with a high risk of falling, such as walking on slippery ice, carrying an overflowing cup of water, or muscle weakness owing to aging or motor deficit. However, previous studies have shown that a normal gait pattern at low speeds results in reduced efficiency and stability in comparison with those at a normal speed. (...) Another possible strategy is to change the gait pattern from normal to step-to gait, in which the other foot is aligned with the first swing foot. However, the efficiency and stability of the step-to gait pattern at low speeds have not been investigated yet. Therefore, in this study, we compared the efficiency and stability of the normal and step-to gait patterns at intermediate, low, and very low speeds. Eleven healthy participants were asked to walk with a normal gait and step-to gait on a treadmill at five different speeds, ranging from very low to normal walking speed. The efficiency parameters and stability parameters were analyzed from the motion capture data and then compared for the two gait patterns. The results suggested that step-to gait had a more efficient gait pattern at very low speeds of 10–30 m/min, with a larger percent recovery, and was more stable at 10–60 m/min in comparison with a normal gait. However, the efficiency of the normal gait was better than that of the step-to gait pattern at 60 m/min. Therefore, step-to gait is effective in improving gait efficiency and stability when faced with situations that force us to walk slowly or hinder quick walking because of muscle weakness owing to aging or motor deficit along with a high risk of falling. (shrink)

Objective:This study aimed to investigate the effect of robot-assisted gait training therapy combined with non-invasive brain stimulation on lower limb function in patients with stroke and spinal cord injury.Data sourcesPubMed, Cochrane Central Register of Controlled Trials, Ovid MEDLINE, and Web of Science were searched.Study selectionRandomized controlled trials published as of 3 March 2021. RCTs evaluating RAGT combined with NIBS, such as transcranial direct current stimulation and repetitive transcranial magnetic stimulation, for lower limb function and activities in patients with stroke and (...) SCI were included.Data extractionTwo reviewers independently screened the records, extracted the data, and assessed the risk of bias.Data synthesisA meta-analysis of five studies and risk of bias were conducted. Pooled estimates demonstrated that RAGT combined with NIBS significantly improved lower limb function [standardized mean difference = 0.52; 95% confidence interval = 0.06–0.99] but not lower limb activities. Subgroup analyses also failed to find a greater improvement in lower limb function of RAGT with tDCS compared to sham stimulation. No significant differences between participant characteristics or types of NIBS were observed.ConclusionThis meta-analysis demonstrated that RAGT therapy in combination with NIBS was effective in patients with stroke and SCI. However, a greater improvement in lower limb function and activities were not observed using RAGT with tDCS compared to sham stimulation. (shrink)

The objective of this study is to design a laboratory experiment to explore the effect of ambiguity on a subject’s search behavior in a finite-horizon sequential search model. In so doing, we employ a strategy to observe the potential trend of reservation points that is usually unobserved. We observe that subjects behaving consistently across treatments reduce their reservation points in the face of ambiguity over point distribution. Our result is consistent with the theoretical implication obtained by Nishimura and Ozaki.

In response to contagion, competing and contradictory movements emerge that engender openness to new modes of life and reactionary defenses of old ones, that acknowledge mutual dependency and vulnerability and that heighten the policing and surveillance of borders. Through reading the Empire project, this article articulates these as struggles over measure that unfold on the terrain of sovereignty and biopolitical economy. We show that the passage from modern to imperial sovereignty hinges on the former’s inability to adequately impose calculatory regimes, (...) to which the latter’s flexibility and fluidity responds. This accompanies the passage from industrial to biopolitical command, from regulation through the wage to rearbitration through extractivism. Having articulated the contemporary coordinates within which the multitude finds itself, we then propose an educational weapon for the struggle against sovereignty and capital: stupidity. Turning to Jean-François Lyotard, we demonstrate just how fundamentally the rule of Empire depends on the outside of measure for its continual reproduction, and how Empire frames the communicative networks of biopolitical labor, a framing from which Hardt and Negri haven’t adequately broken. As the other of thought, as that which can’t be articulated, commanded, or absorbed by capital, stupidity remains totally useless and unproductive for Empire, which is exactly where its potency lies for the multitude. By critically engaging stupidity, we can refrain from reducing the pandemic to a need for heightened immunity and enclosure achieved through articulation. (shrink)

Louveau showed that if a Borel set in a Polish space happens to be in a Borel Wadge class $$\Gamma $$, then its $$\Gamma $$ -code can be obtained from its Borel code in a hyperarithmetical manner. We extend Louveau’s theorem to Borel functions: If a Borel function on a Polish space happens to be a $$ \underset{\widetilde{}}{\varvec{\Sigma }}\hbox {}_t$$ -function, then one can find its $$ \underset{\widetilde{}}{\varvec{\Sigma }}\hbox {}_t$$ -code hyperarithmetically relative to its Borel code. More generally, we prove (...) extension-type, domination-type, and decomposition-type variants of Louveau’s theorem for Borel functions. (shrink)

We introduce a Gentzen style formulation of Basic Propositional Calculus(BPC), the logic that is interpreted in Kripke models similarly tointuitionistic logic except that the accessibility relation of eachmodel is not necessarily reflexive. The formulation is presented as adual-context style system, in which the left hand side of a sequent isdivided into two parts. Giving an interpretation of the sequents inKripke models, we show the soundness and completeness of the system withrespect to the class of Kripke models. The cut-elimination theorem isproved (...) in a syntactic way by modifying Gentzen's method. Thisdual-context style system exemplifies the effectiveness of dual-contextformulation in formalizing various non-classical logics. (shrink)

In the natural deduction system for classical propositional logic given by G. Gentzen, there are some inference rules with assumptions discharged by the rule. D. Prawitz calls such inference rules improper, and others proper. Improper inference rules are more complicated and are often harder to understand than the proper ones. In the present paper, we distinguish between proper and improper derivations by using sequent systems. Specifically, we introduce a sequent system \(\vdash_{\bf Sc}\) for classical propositional logic with only structural rules, (...) and prove that \(\vdash_{\bf Sc}\) does not allow improper derivations in general. For instance, the sequent \(\Rightarrow p \to q\) cannot be derived from the sequent \(p \Rightarrow q\) in \(\vdash_{\bf Sc}\). In order to prove the failure of improper derivations, we modify the usual notion of truth valuation, and using the modified valuation, we prove the completeness of \(\vdash_{\bf Sc}\). We also consider whether an improper derivation can be described generally by using \(\vdash_{\bf Sc}\). (shrink)

Gene regulation involves various cis-regulatory elements that can act at a distance. They may physically interact each other or with their target genes to exert their effects. Such interactions are beginning to be uncovered in the imprinted Igf2/H19 domain.1 The differentially methylated regions (DMRs), containing insulators, silencers and activators, were shown to have physical contacts between them. The interactions were changeable depending on their epigenetic state, presumably enabling Igf2 to move between an active and a silent chromatin domain. The study (...) gives us a novel view on how regulatory elements influence gene expression and how epigenetic modifications modulate their long-range effects. (shrink)