Richard Rorty's philosophy has two basic commitments: one to postmodernism and the other to liberalism. However, these commitments generate tension. As a postmodernist, he sharply criticizes the Enlightenment; as a liberal, he forcefully defends it. His postmodernist liberalism actually explains liberalism using irrationalism. /// 罗蒂哲学有两个基本承诺，一个是对后现代主义的承诺，一个是对自由主义 的承诺。但是这两种承诺之间存在着紧张关系: 作为后现代主义者，罗蒂对启蒙提 出了强烈的批评; 作为自由主义者，他又在极力地维护启蒙。罗蒂的后现代自由主 义实质上是以非理性主义来解释自由主义。.

本书以西方诠释学为参照,以《论语》、《孟子》、《荀子》为个案,对先秦儒家的意义生成问题及其特点与具体表现作出了独特而深入的阐析。.

Cancer drugs are broadly classified into two categories: cytotoxic chemotherapies and targeted therapies that specifically modulate the activity of one or more proteins involved in cancer. Major advances have been achieved in targeted cancer therapies in the past few decades, which is ascribed to the increasing understanding of molecular mechanisms for cancer initiation and progression. Consequently, monoclonal antibodies and small molecules have been developed to interfere with a specific molecular oncogenic target. Targeting gain‐of‐function mutations, in general, has been productive. However, (...) it has been a major challenge to use standard pharmacologic approaches to target loss‐of‐function mutations of tumor suppressor genes. Novel approaches, including synthetic lethality and collateral vulnerability screens, are now being developed to target gene defects in p53, PTEN, and BRCA1/2. Here, we review and summarize the recent findings in cancer genomics, drug development, and molecular cancer biology, which show promise in targeting tumor suppressors in cancer therapeutics. (shrink)

In this paper we examine the pattern of conceptual change during scientific revolutions by using methods from cognitive psychology. We show that the changes characteristic of scientific revolutions, especially taxonomic changes, can occur in a continuous manner. Using the frame model of concept representation to capture structural relations within concepts and the direct links between concept and taxonomy, we develop an account of conceptual change in science that more adequately reflects the current understanding that episodes like the Copernican revolution are (...) not always abrupt. When concepts are represented by frames, the transformation from one taxonomy to another can be achieved in a piecemeal fashion not preconditioned by a crisis stage, and a new taxonomy can arise naturally out of the old frame instead of emerging separately from the existing conceptual system. This cognitive mechanism of continuous change demonstrates the constructive roles of anomaly and incommensurability in promoting the progress of science. (shrink)

In this paper I examine a cognitive mechanism of incommensurability. Using the frame model of concept representation to capture structural relations within concepts, I reveal an ontological difference between object and event concepts: the former are spatial but the latter temporal. Experiments from cognitive sciences further demonstrate that the mind treats object and event concepts differently. Thus, incommensurability can occur in conceptual change across different ontological categories. I use a historical case to illustrate how the ontological difference between an object (...) and an event concept actually caused incommensurability in the context of nineteenth‐century optics. The cognitive and historical analyses indicate that incommensurability can be a local phenomenon and does not necessarily imply incomparability. (shrink)

To correct the misconception that incommensurability implies incomparability, Kuhn lately develops a new interpretation of incommensurability. This includes a linguistic theory of scientific revolutions (the theory of kinds), a cognitive exploration of the language learning process (the analogy of bilingualism), and an epistemological discussion on the rationality of scientific development (the evolutionary epistemology). My focus in this paper is to review Kuhn's effort in eliminating relativism, highlighting both the insights and the difficulties of his new version of incommensurability . Finally (...) I suggest that some of Kuhn's difficulties can be overcome by adopting a concept of rationality that filly appreciates the important role of instruments in the development of science. (shrink)

: This paper offers a preliminary analysis of conceptual change between event concepts. It begins with a brief review of the major findings of cognitive studies on event knowledge. The script model proposed by Schank and Abelson was the first attempt to represent event knowledge. Subsequent cognitive studies indicated that event knowledge is organized in the form of dimensional organizations in which temporally successive actions are related causally. This paper proposes a frame representation to capture and outline the internal structure (...) of event concepts, in particular, their causal connections. The frame representation offers an effective method to analyze the relations between event concepts, and to expose the unique cognitive mechanisms behind conceptual change involved event concepts. Finally this paper shows that the frame representation of event concepts is instrumental to understanding an important historical episode of conceptual change in the context of nineteenth-century optics. (shrink)

In a previous article we have shown that Kuhn's theory of concepts is independently supported by recent research in cognitive psychology. In this paper we propose a cognitive re-reading of Kuhn's cyclical model of scientific revolutions: all of the important features of the model may now be seen as consequences of a more fundamental account of the nature of concepts and their dynamics. We begin by examining incommensurability, the central theme of Kuhn's theory of scientific revolutions, according to two different (...) cognitive models of concept representation. We provide new support for Kuhn 's mature views that incommensurability can be caused by changes in only a few concepts, that even incommensurable conceptual systems can be rationally compared, and that scientific change of the most radical sort—the type labeled revolutionary in earlier studies—does not have to occur holistically and abruptly, but can be achieved by a historically more plausible accumulation of smaller changes. We go on to suggest that the parallel accounts of concepts found in Kuhn and in cognitive science lead to a new understanding of the nature of normal science, of the transition from normal science to crisis, and of scientific revolutions. The same account enables us to understand how scientific communities split to create groups supporting new paradigms, and to resolve various outstanding problems. In particular, we can identify the kind of change needed to create a revolution rather precisely. This new analysis also suggests reasons for the unidirectionality of scientific change. (shrink)

ABSTRACT Although much has been written about Chinese students’ understandings of illegitimate intertextual practices, few studies have investigated Chinese university teachers’ perceptions of plagiarism, let alone the effects of their disciplinary background on their knowledge of and attitudes toward plagiarism. This paper reports on a study that examined the knowledge that 128 Chinese university teachers of different disciplinary backgrounds had of plagiarism, their attitudes toward identified plagiarism, and their own ability to engage in legitimate paraphrasing. Multiple regression analyses showed that (...) disciplinary background and teaching experience were significant predictors of the participants’ knowledge of plagiarism, whereas disciplinary background and overseas experience significantly predicted their stance on plagiarism. A logistic regression analysis identified disciplinary background as a significant predictor of the participants’ ability to produce legitimate paraphrases. Qualitative analyses of the participants’ open-ended responses revealed that their criteria for plagiarism aligned with Anglo-American conceptions of plagiarism and that intertextual competence was dependent in no small measure on linguistic competence. (shrink)

This paper offers a solution to a problem in Herschel studies by drawing on the dynamic frame model for concept representation offered by cognitive psychology. Applying the frame model to represent the conceptual frameworks of the particle and wave theories, this paper shows that discontinuity between the particle and wave frameworks consists mainly in the transition from a particle notion ‘side’ to a wave notion ‘phase difference’. By illustrating intraconceptual relations within concepts, the frame representations reveal the ontological differences between (...) these two concepts. ‘Side’ is an object concept built on spatial relations, but ‘phase difference’ is an event concept built on temporal relations. The conceptual analyses display a possible cognitive source of Herschel’s misconception of polarization. Limited by his experimental works and his philosophical beliefs, Herschel comprehended polarization solely in terms of spatial relations, which prevented him from replacing the object concept ‘side’ with the event concept ‘phase difference’, and eventually resulted in his failure to understand the wave account of polarization.Author Keywords: Herschel; Polarization; Object concept; Event concept; Frame; Cognitive psychology. (shrink)

Previous studies of the history of optics reveal that the confrontation between the emission theory of light and the undulatory theory of light in Britain occupied a considerable period during the early nineteenth century. After the majority of British physicists accepted the undulatory theory in the mid-1830s a few emissionists in Britain did not immediately surrender. They continued to fight a rear-guard action against the undulatory theory, hoping that someday they could reinstate their theory.’ The longevity of the confrontation between (...) the emission and the undulatory theory is consistent with recent philosophical and sociological accounts of science, which expect scientific controversy to last a considerable time. Lakatos’s philosophical account, for example, holds that a degenerating theory does not disappear immediately and may revive at any time through a burst of ‘heuristic power’. But this account only allows one universal standard-the verification of excess empirical content-as the basis for both the generation and the closure of scientific controversies.’ On the other hand, sociological accounts such as actor-network theory have also done much to dispel the impression that rapid closure is inevitable in scientific controversies. But perhaps they risk a new orthodoxy: that controversy itself is inevitable. (shrink)

本书系统梳理了中国传统忠伦理的起源,演变等脉络和轨迹,深入挖掘了其在不同历史时期的内涵及价值,从而汲取传统忠伦理的尽心尽力,忠心奉公等丰厚滋养,使忠的核心观念与社会主义核心价值观中的"爱国""敬业"" 诚信""友善"等有机衔接,融通, 建构现代忠诚观念,以更好地将忠于国家和人民的社会公德,忠于职守的职业道德,忠于家庭的家庭美德,忠于他人的个人品德等伦理原则付诸实践.

Problem and Project Based Learning (PBL) has been used as an educational philosophy and methodology in the construction of a student centered and contextualized learning environment. PBL is also regarded as an effective method in producing engineering graduates who can not only meet the needs of professional competences but are also prepared for new challenges in the globalized and technological context. However, can PBL be a solution to the challenge of a general lack of university students studying engineering and technology (...) in many countries? Gender and Diversity in a Problem and Project Based Learning Environment presents an ethnographical study on the learning experiences of engineering students in the PBL environment in Denmark, and it attempts to question the issue of diversity in engineering education via the exploration of which ways the PBL environment is friendly to diverse groups of learners such as women. (shrink)

I propose a new perspective on the study of scientific revolutions. This is a transformation from an object-only perspective to an ontological perspective that properly treats objects and processes as distinct kinds. I begin my analysis by identifying an object bias in the study of scientific revolutions, where it takes the form of representing scientific revolutions as changes in classification of physical objects. I further explore the origins of this object bias. Findings from developmental psychology indicate that children cannot distinguish (...) processes from objects until the age of 7, but they have already developed a core system of object knowledge as early as 4 months of age. The persistence of this core system is responsible for the object bias among mature adults, i.e., the tendency to apply knowledge of physical objects to temporal processes. In light of the distinction between physical objects and temporal processes, I redraw the picture of the Copernican revolution. Rather than seeing it as a taxonomic shift from a geocentric to a heliocentric cosmology, we should understand it as a transformation from a conceptual system that was built around an object concept to one that was built around a process concept. (shrink)

In this article I explain why scientists cannot always resolve their disagreements about experiments even if they do not hold conflicting theoretical assumptions, and how incommensurability in experiments can occur even if experiments are not deeply encumbered by theoretical assumptions. On the basis of recent discoveries in cognitive psychology and an extended analysis of a historical case, I explore a cognitive mechanism that may generate incommensurability in experiment appraisal. I find that, because of the involvement of goal-derived categories, incommensurability in (...) experiments may result from the conflict of goals that scientists pursue in their researches, from the differences of goal-derived classification schemata that they employ in analyzing experiments, and from discrepancies between skills that they have developed in their practices. This account differs from the conventional interpretation of Kuhn’s thesis, which attributes the cause of incommensurability solely to theoretical differences. In the conclusion, I further discuss the implications of this new account of incommensurability for both philosophical and historical studies of science. (shrink)

Emotional design is an important development trend of interaction design. Emotional design in products plays a key role in enhancing user experience and inducing user emotional resonance. In recent years, based on the user's emotional experience, the design concept of strengthening product emotional design has become a new direction for most designers to improve their design thinking. In the emotional interaction design, the machine needs to capture the user's key information in real time, recognize the user's emotional state, and use (...) a variety of clues to finally determine the appropriate user model. Based on this background, this research uses a deep learning mechanism for more accurate and effective emotion recognition, thereby optimizing the design of the interactive system and improving the user experience. First of all, this research discusses how to use user characteristics such as speech, facial expression, video, heartbeat, etc., to make machines more accurately recognize human emotions. Through the analysis of various characteristics, the speech is selected as the experimental material. Second, a speech-based emotion recognition method is proposed. The mel-Frequency cepstral coefficient of the speech signal is used as the input of the improved long and short-term memory network. To ensure the integrity of the information and the accuracy of the output at the next moment, ILSTM makes peephole connections in the forget gate and input gate of LSTM, and adds the unit state as input data to the threshold layer. The emotional features obtained by ILSTM are input into the attention layer, and the self-attention mechanism is used to calculate the weight of each frame of speech signal. The speech features with higher weights are used to distinguish different emotions and complete the emotion recognition of the speech signal. Experiments on the EMO-DB and CASIA datasets verify the effectiveness of the model for emotion recognition. Finally, the feasibility of emotional interaction system design is discussed. (shrink)

One of the most controversial ideas in recent philosophy of science is the incommensurability of scientific theories. For Kuhn, the claim that two theories are incommensurable is the claim that there is no common language within which both theories could be fully expressed (Kuhn 1977, p. 301). In others words, two theories are incommensurable if and only if they are articulated in languages that are not mutually translatable or communicable without loss. This type of incommensurability, according to Kuhn, is the (...) result of changes in worldview. The proponents of different paradigms practice their researches in different worlds (Kuhn 1970, p. 150). They may have different classifications of objects in the world due to their different cultures. For example, the astronomers who belonged to Ptolemy’s paradigm grouped the sun, moon, and Mars into the same set, while the astronomers who belonged to Copernicus’s paradigm classified them into three different categories. (shrink)

Surveys of public opinions on climate change found that a majority of American respondents regarded global warming as a critical or an important threat . Given this consensus, one might expect that a majority of Americans are ready to take immediate action to deal with the environmental crisis. However, when they were asked whether we should begin taking steps now, only 43% of American respondents said yes; 54% of them chose either the option “until we are sure that global warming (...) is really a problem, we should not take any steps that would have economic costs,” or the option “global warming should be addressed, but its effects will be gradual, so we can deal with the problem .. (shrink)

Histone post-translational modifications play important roles in transcriptional regulation. It is known that multiple histone modifications can act in a combinatorial manner. In this study, we investigated the effects of multiple histone modifications on expression levels of five gene categories in coding regions. The combinatorial patterns of modifications for the five gene categories were also studied in the regions. Our results indicated that the differences in the expression levels between any two gene categories were significant. There were some corresponding differences (...) in multiple histone modification levels among the five gene categories. Multiple histone modifications jointly impacted expression levels of every gene category. Four mutual combinations of histone modifications were found and analyzed. (shrink)

本书是作者的论文集,包括科技革命与两种社会制度的嬗变、全球化问题研究、“第三条道路”与社会福利制度改革三部分。附:新科技革命对两种社会制度的挑战——高放教授访谈录。.

The rapid acceleration of societal change has subjected contemporary individuals to prolonged periods of diverse pressures, leading to substantial psychological strain, resulting in anxiety, depression, and compromised mental well-being. Within this context, the home has evolved into a vital refuge for modern individuals, offering both physical and psychological respite. Through experimental intervention, this study examines two distinct residential groups: those adhering to traditional housing and those residing in characteristic folk houses, specifically Gannan Hakka architecture. Analysing the psychological state of contemporary (...) individuals and integrating Gannan Hakka architectural elements into folk house design through a psychologically informed approach, this research aims to enhance residents’ aesthetic experiences and alleviate psychological distress. The study involved 120 volunteers with varying psychological stress levels, categorised into characteristic and traditional folk house groups. Psychological assessments evaluated stress, self-efficacy, and quality of life. Findings reveal significantly improved psychological well-being, self-efficacy, and quality of life among the characteristic residential group, affirming the benefits of Gannan Hakka architecture integration. This research underscores the importance of addressing modern individuals’ environmental needs and proposes the integration of Gannan Hakka cultural elements into residential design to enhance well-being. Contribution: This study demonstrates the application of Hakka culture in contemporary housing profoundly influences residents’ lives, enabling both relaxation and a deeper cultural connection. This integration facilitates a comprehensive understanding of Hakka culture, promoting its preservation. Notably recognised for hospitality and diligence, Hakka culture enhances individuals’ appreciation of tradition, fostering physical and mental rejuvenation. These findings offer valuable insights for practical theology scholars and practitioners exploring the impact of religious aspects on modern residential design from a psychological perspective. (shrink)

I propose a new perspective with which to understand scientific revolutions. This is a conversion from an object-only perspective to one that properly treats object and process concepts as distinct kinds. I begin with a re-examination of the Copernican revolution. Recent findings from the history of astronomy suggest that the Copernican revolution was a move from a conceptual framework built around an object concept to one built around a process concept. Drawing from studies in the cognitive sciences, I then show (...) that process concepts are independent of object concepts, grounded in specific regions of the brain and involving unique representational mechanisms. There are cognitive obstacles to the transformation from object to process concepts, and an object bias—a tendency to treat processes as objects—makes this kind of conceptual change difficult. Consequently, transformation from object to process concepts is disruptive and revolutionary. Finally, I explore the implications of this new perspective on scientific revolutions for both the history and philosophy of science.Keywords: Scientific revolutions; Process concepts; Object concepts; Object bias; Copernican revolution. (shrink)

When a widely reused ontology appears in a new version which is not compatible with older versions, the ontologies reusing it need to be updated accordingly. Ontobull has been developed to automatically update ontologies with new term IRI(s) and associated metadata to take account of such version changes. To use the Ontobull web interface a user is required to (i) upload one or more ontology OWL source files; (ii) input an ontology term IRI mapping; and (where needed) (iii) provide update (...) settings for ontology headers and XML namespace IDs. Using this information, the backend Ontobull Java program automatically updates the OWL ontology files with desired term IRIs and ontology metadata. The Ontobull subprogram BFOConvert supports the conversion of an ontology that imports a previous version of BFO. A use case is provided to demonstrate the features of Ontobull and BFOConvert. (shrink)

Memory limitations and probabilistic expectations are two key factors that have been posited to play a role in the incremental processing of natural language. Relative clauses (RCs) have long served as a key proving ground for such theories of language processing. Across three self-paced reading experiments, we test the online comprehension of Hungarian subject- and object-extracted RCs (SRCs and ORCs, respectively). We capitalize on the syntactic properties of Hungarian that allow for a variety of word orders within RCs, which helps (...) us to delineate the processing costs associated with memory demand and violated expectations. Results showed a processing cost at the RC verb for structures that have longer verb-argument distances, despite those structures being more frequent in the corpus. These findings thus support theories that attribute processing difficulty to memory limitations, rather than theories that attribute difficulty to less expected structures. (shrink)

More and more research on left ventricle quantification skips segmentation due to its requirement of large amounts of pixel-by-pixel labels. In this study, a framework is developed to directly quantify left ventricle multiple indices without the process of segmentation. At first, DenseNet is utilized to extract spatial features for each cardiac frame. Then, in order to take advantage of the time sequence information, the temporal feature for consecutive frames is encoded using gated recurrent unit. After that, the attention mechanism is (...) integrated into the decoder to effectively establish the mappings between the input sequence and corresponding output sequence. Simultaneously, a regression layer with the same decoder output is used to predict multi-indices of the left ventricle. Different weights are set for different types of indices based on experience, and l2-norm is used to avoid model overfitting. Compared with the state-of-the-art, our method can not only produce more competitive results but also be more flexible. This is because the prediction results in our study can be obtained for each frame online while the SOTA only can output results after all frames are analyzed. (shrink)

Many empirical studies have been conducted to investigate self-regulated learning in the Western countries. Less well investigated is the SRL in the Chinese Mainland students and how it affects their academic achievement. On the basis of PISA 2009, this paper is aimed at exploring the SRL of 15-year-old Shanghai students, as measured by cognitive strategy, metacognition, and motivational belief. In the aspect of SRL nature, the results reveal that 15-year-old students in Shanghai use elaboration strategy frequently and seldom use memorization (...) strategy, and that they have high metacognition in understanding, remembering, and summarizing but have low control strategy, and that their enjoyment of reading is relatively high. In the aspect of SRL’s consequence for reading literacy, findings from multilevel linear regression corroborate previous evidence from the Western countries about the effect of SRL on academic achievement. Specifically, elaboration strategy, metacognition in understanding and remembering, metacognition in summarizing, control strategy, and enjoyment of reading are conducive to students’ reading literacy, while memorization strategy exerts a significantly negative effect on reading literacy. The findings could be useful in helping us to gain a better understanding of Shanghai students’ SRL. (shrink)

This paper concentrates on a debate over dispersion in the second half of the 1830s, in which both sides utilized the same set of experimental data to test a proposed wave account of dispersion, but could not agree on how these data should be used. The conflict regarding experimental data was caused by differences in instruments. In the debate, optical instruments in many ways functioned like paradigms, shaping scientists' opinions. Instruments also led the debate into an impasse, because no apparatus (...) was available for the necessary experimental replication. Because of unreconcilable differences regarding experimental evidence, the wave theory's failure in explaining dispersion did not become an obstacle to its acceptance. (shrink)