29 found
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  1.  74
    Moral enhancement and pro-social behaviour.Sarah Chan & John Harris - 2011 - Journal of Medical Ethics 37 (3):130-131.
    Moral enhancement is a topic that has sparked much current interest in the world of bioethics. The possibility of making people ‘better,’ not just in the conventional enhancement sense of improving health and other desirable qualities and capacities, but by making them somehow more moral, more decent, altogether better people, has attracted attention from both advocates 1 2 and sceptics 3 alike. The concept of moral enhancement, however, is fraught with difficult questions, theoretical and practical. What does it actually mean (...)
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  2.  30
    Public involvement in the governance of population-level biomedical research: unresolved questions and future directions.Sonja Erikainen, Phoebe Friesen, Leah Rand, Karin Jongsma, Michael Dunn, Annie Sorbie, Matthew McCoy, Jessica Bell, Michael Burgess, Haidan Chen, Vicky Chico, Sarah Cunningham-Burley, Julie Darbyshire, Rebecca Dawson, Andrew Evans, Nick Fahy, Teresa Finlay, Lucy Frith, Aaron Goldenberg, Lisa Hinton, Nils Hoppe, Nigel Hughes, Barbara Koenig, Sapfo Lignou, Michelle McGowan, Michael Parker, Barbara Prainsack, Mahsa Shabani, Ciara Staunton, Rachel Thompson, Kinga Varnai, Effy Vayena, Oli Williams, Max Williamson, Sarah Chan & Mark Sheehan - 2021 - Journal of Medical Ethics 47 (7):522-525.
    Population-level biomedical research offers new opportunities to improve population health, but also raises new challenges to traditional systems of research governance and ethical oversight. Partly in response to these challenges, various models of public involvement in research are being introduced. Yet, the ways in which public involvement should meet governance challenges are not well understood. We conducted a qualitative study with 36 experts and stakeholders using the World Café method to identify key governance challenges and explore how public involvement can (...)
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  3.  91
    Free riders and pious sons – why science research remains obligatory.Sarah Chan & John Harris - 2008 - Bioethics 23 (3):161-171.
    John Harris has previously proposed that there is a moral duty to participate in scientific research. This concept has recently been challenged by Iain Brassington, who asserts that the principles cited by Harris in support of the duty to research fail to establish its existence. In this paper we address these criticisms and provide new arguments for the existence of a moral obligation to research participation. This obligation, we argue, arises from two separate but related principles. The principle of fairness (...)
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  4.  20
    A bioethics for all seasons.Sarah Chan - 2015 - Journal of Medical Ethics 41 (1):17-21.
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  5. In Support of Human Enhancement.Sarah Chan & John Harris - 2007 - Studies in Ethics, Law, and Technology 1 (1).
  6.  78
    Genome Editing Technologies and Human Germline Genetic Modification: The Hinxton Group Consensus Statement.Sarah Chan, Peter J. Donovan, Thomas Douglas, Christopher Gyngell, John Harris, Robin Lovell-Badge, Debra J. H. Mathews, Alan Regenberg & On Behalf of the Hinxton Group - 2015 - American Journal of Bioethics 15 (12):42-47.
    The prospect of using genome technologies to modify the human germline has raised profound moral disagreement but also emphasizes the need for wide-ranging discussion and a well-informed policy response. The Hinxton Group brought together scientists, ethicists, policymakers, and journal editors for an international, interdisciplinary meeting on this subject. This consensus statement formulated by the group calls for support of genome editing research and the development of a scientific roadmap for safety and efficacy; recognizes the ethical challenges involved in clinical reproductive (...)
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  7.  6
    Contested futures: envisioning “Personalized,” “Stratified,” and “Precision” medicine.Sonja Erikainen & Sarah Chan - 2019 - New Genetics and Society 38 (3):308-330.
    In recent years, discourses around “personalized,” “stratified,” and “precision” medicine have proliferated. These concepts broadly refer to the translational potential carried by new data-intensive biomedical research modes. Each describes expectations about the future of medicine and healthcare that data-intensive innovation promises to bring forth. The definitions and uses of the concepts are, however, plural, contested and characterized by diverse ideas about the kinds of futures that are desired and desirable. In this paper, we unpack key disputes around the “personalized,” “stratified,” (...)
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  8.  61
    Does a Fish Need a Bicycle? Animals and Evolution in the Age of Biotechnology.Sarah Chan & John Harris - 2011 - Cambridge Quarterly of Healthcare Ethics 20 (3):484-492.
    Animals, in the age of biotechnology, are the subjects of a myriad of scientific procedures, interventions, and modifications. They are created, altered, and experimented upon—often with highly beneficial outcomes for humans in terms of knowledge gained and applied, yet not without concern also for the effects upon the experimental subjects themselves: consideration of the use of animals in research remains an intensely debated topic. Concerns for animal welfare in scientific research have, however, been primarily directed at harm to and suffering (...)
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  9.  26
    How to Rethink the Fourteen‐Day Rule.Sarah Chan - 2017 - Hastings Center Report 47 (3):5-6.
    Recently, attention has been drawn to the basic principles governing the use of human embryos in research: specifically, the so-called fourteen-day rule. This rule stipulates that human embryos should not be allowed to grow in vitro past fourteen days of development. For years, the fourteen-day limit was largely theoretical, since culture techniques were not sufficient to maintain embryos up to this point. Yet in the past year, research has suggested that growing embryos beyond fourteen days might be feasible and scientifically (...)
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  10.  24
    Commentary on ‘Moral reasons to edit the human genome’: this is not the moral imperative we are looking for.Sarah Chan - 2019 - Journal of Medical Ethics 45 (8):528-529.
    After reading Savulescu and colleagues,1 one ought to be in no doubt that human heritable genome editing is a ‘moral imperative’: to cure disease, reduce inequalities, improve public health and protect future generations. They make this argument repeatedly and in no uncertain terms. Yet are they right to do so? I am certainly not against developing HGE or exploring its possibilities. Instead, I aim to sound a cautionary note in relation to claims about its technological potential and how we frame (...)
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  11.  29
    What's in a Name? The Politics of ‘Precision Medicine’.Sarah Chan & Sonja Erikainen - 2018 - American Journal of Bioethics 18 (4):50-52.
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  12. Families – Beyond the Nuclear Ideal.Daniela Cutas & Sarah Chan - 2012 - Bloomsbury Academic.
    This book examines, through a multi-disciplinary lens, the possibilities offered by relationships and family forms that challenge the nuclear family ideal, and some of the arguments that recommend or disqualify these as legitimate units in our societies. That children should be conceived naturally, born to and raised by their two young, heterosexual, married to each other, genetic parents; that this relationship between parents is also the ideal relationship between romantic or sexual partners; and that romance and sexual intimacy ought to (...)
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  13.  64
    Mitochondrial Replacement Techniques, Scientific Tourism, and the Global Politics of Science.Sarah Chan, César Palacios-González & María De Jesús Medina Arellano - 2017 - Hastings Center Report 47 (5):7-9.
    The United Kingdom is the first and so far only country to pass explicit legislation allowing for the licensed use of the new reproductive technology known as mitochondrial replacement therapy. The techniques used in this technology may prevent the transmission of mitochondrial DNA diseases, but they are controversial because they involve the manipulation of oocytes or embryos and the transfer of genetic material. Some commentators have even suggested that MRT constitutes germline genome modification. All eyes were on the United Kingdom (...)
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  14.  19
    Playing it Safe? Precaution, Risk, and Responsibility in Human Genome Editing.Sarah Chan - 2020 - Perspectives in Biology and Medicine 63 (1):111-125.
    On November 26, 2018, the world awoke to the news that genome editing had for the first time been used to create genetically modified human beings. He Jiankui, a scientist then employed by Southern University of Science and Technology of China, Shenzhen, announced via social media and the popular press that he had performed genome editing on embryos with the aim of disrupting the CCR5 gene in order to induce immunity to HIV, implanted the embryos, and that twin girls had (...)
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  15.  35
    Hidden Anthropocentrism and the “Benefit of the Doubt”: Problems With the “Origins” Approach to Moral Status.Sarah Chan - 2014 - American Journal of Bioethics 14 (2):18-20.
  16.  13
    1.4 Science and the Social Contract: On the Purposes, Uses and Abuses of Science.Sarah Chan, John Harris & John Sulston - forthcoming - Common Knowledge: The Challenge of Transdisciplinarity.
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  17.  14
    Research Translation and Emerging Health Technologies: Synthetic Biology and Beyond.Sarah Chan - 2018 - Health Care Analysis 26 (4):310-325.
    New health technologies are rapidly emerging from various areas of bioscience research, such as gene editing, regenerative medicine and synthetic biology. These technologies raise promising medical possibilities but also a range of ethical considerations. Apart from the issues involved in considering whether novel health technologies can or should become part of mainstream medical treatment once established, the process of research translation to develop such therapies itself entails particular ethical concerns. In this paper I use synthetic biology as an example of (...)
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  18.  41
    Commentary: What Price Freedom?Sarah Chan - 2017 - Cambridge Quarterly of Healthcare Ethics 26 (3):377-383.
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  19. Rethinking the posthuman in bioethics.David Boden & Sarah Chan - 2022 - In Danielle Sands (ed.), Bioethics and the Posthumanities. New York, NY: Routledge.
     
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  20.  9
    Bioética y bioderecho: reflexiones clásicas y nuevos desafíos.Sarah Chan, Ibarra Palafox, A. Francisco, Medina Arellano & María de Jesús (eds.) - 2018 - Ciudad de México, México: Universidad Nacional Autónoma de México, Instituto de Investigaciones Jurídicas.
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  21.  62
    Consequentialism without Consequences: Ethics and Embryo Research.Sarah Chan & John Harris - 2010 - Cambridge Quarterly of Healthcare Ethics 19 (1):61.
    The legitimacy of embryo research, use, and destruction is among the most important issues facing contemporary bioethics. In the preceding paper, Ingmar Persson and Julian Savulescu took up an argument of John Harris and tried to find some new ways of avoiding its dramatic consequences. They noted that: “John Harris has argued that if … it is morally permissible to engage in reproduction … despite knowledge that a large number of embryos will fail to implant and quickly die, then … (...)
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  22.  76
    Frozen embryos, genetic information and reproductive rights.Sarah Chan & Muireann Quigley - 2007 - Bioethics 21 (8):439–448.
    Recent ethical and legal challenges have arisen concerning the rights of individuals over their IVF embryos, leading to questions about how, when the wishes of parents regarding their embryos conflict, such situations ought to be resolved. A notion commonly invoked in relation to frozen embryo disputes is that of reproductive rights: a right to have (or not to have) children. This has sometimes been interpreted to mean a right to have, or not to have, one's own genetic children. But can (...)
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  23.  20
    In search of a post-genomic bioethics: Lessons from Political Biology.Sarah Chan - 2018 - History of the Human Sciences 31 (1):116-123.
  24. Modification and the future of health research regulation.Sarah Chan - 2021 - In Graeme T. Laurie (ed.), The Cambridge handbook of health research regulation. New York, NY: Cambridge University Press.
     
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  25.  40
    ‘Risky’ research and participants' interests: the ethics of phase 2C clinical trials.Sarah Chan, Ying-Kiat Zee, Gordon Jayson & John Harris - 2011 - Clinical Ethics 6 (2):91-96.
    Biomedical research involving human participants is highly regulated and subject to stringent ethical requirements. Clinical research ethics, regulation and policy have tended to focus almost exclusively on the protection of participants' interests against harms that might result from taking part in research. Less consideration, however, has been given to the interests that patients may themselves have in research participation, even in trials that may be beyond the bounds of current clinical research practice. In this paper, we consider the case of (...)
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  26. The concise argument.Sarah Chan - 2009 - Journal of Medical Ethics 35 (10):589-589.
    The ethics of psychiatry The ethics of psychiatry is one of the areas of medical ethics where the overlap between medical ethics and philosophy of medicine is largest. This is illustrated by two papers in the current issue of the JME. Charlotte Blease discusses whether it is “… ever right to prescribe placebos to patients in clinical practice?” in the context of prescribing for patients with severe depression . Would such prescriptions for instance amount to morally problematic deception? In an (...)
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  27.  11
    From reason to practice in bioethics: an anthology dedicated to the works of John Harris.John Coggon, Sarah Chan, Søren Holm, Thomasine Kimbrough Kushner & John Harris (eds.) - 2015 - Manchester: Manchester University Press.
    From reason to practice in bioethics brings together original contributions from some of the world's leading scholars in the field of bioethics. With a particular focus on, and critical engagement with, the influential work of Professor John Harris, the book provides a detailed exploration of some of the most interesting and challenging philosophical and practical questions raised in bioethics.
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  28. Stem Cells: New Frontiers in Science and Ethics.Muireann Quigley, Sarah Chan & John Harris (eds.) - 2012 - World Scientific.
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  29.  23
    Beyond the Is/Ought Divide: Studying the Nature of the Bioethical Enterprise. [REVIEW]Sarah Chan & John Coggon - 2013 - Health Care Analysis 21 (1):1-5.
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