BackgroundAdvances in biomedicine can substantially change human life. However, progress is not always followed by ethical reflection on its consequences or scientists’ responsibility for their creations. The humanities can help health sciences students learn to critically analyse these issues; in particular, literature can aid discussions about ethical principles in biomedical research. Mary Shelley’sFrankenstein; or, the modern Prometheus(1818) is an example of a classic novel presenting complex scenarios that could be used to stimulate discussion.Main textWithin the framework of the 200th anniversary (...) of the novel, we searched PubMed to identify works that explore and discuss its value in teaching health sciences. Our search yielded 56 articles, but only two of these reported empirical findings. Our analysis of these articles identified three main approaches to usingFrankensteinin teaching health sciences: discussing the relationship between literature and science, analysing ethical issues in biomedical research, and examining the importance of empathy and compassion in healthcare and research. After a critical discussion of the articles, we propose usingFrankensteinas a teaching tool to prompt students to critically analyse ethical aspects of scientific and technological progress, the need for compassion and empathy in medical research, and scientists’ responsibility for their discoveries.ConclusionFrankensteincan help students reflect on the personal and social limits of science, the connection between curiosity and scientific progress, and scientists’ responsibilities. Its potential usefulness in teaching derives from the interconnectedness of science, ethics, and compassion.Frankensteincan be a useful tool for analysing bioethical issues related to scientific and technological advances, such as artificial intelligence, genetic engineering, and cloning. Empirical studies measuring learning outcomes are necessary to confirm the usefulness of this approach. (shrink)

Network analysis views complex systems as networks with well-defined structural properties that account for their complexity. These characteristics, which include scale-free behavior, small worlds and communities, are not to be found in networks such as random graphs and lattices that do not correspond to complex systems. They provide therefore a robust ground for claiming the existence of “complex networks” as a non-trivial subset of networks. The theory of complex networks has thus been successful in making systematically explicit relevant marks of (...) complexity in the form of structural properties, and this success is at the root of its current popularity. Much less systematic has been, on the other hand, the definition of the properties of the building components of complex networks. The obvious assumption is that these components must be nodes and links. Generally, however, the internal structure of nodes is not taken into account, and links are serendipitously identified by the perspective with which one looks at the network to be analyzed. For instance, if the nodes are Web pages that contain information about scientific papers, one point of view will match the relevant links with hyperlinks to similar Web pages, and another with citations of other articles. We intend to contribute here a systematic approach to the identification of the components of a complex network that is based on information theory. The approach hinges on some recent results arising from the convergence between the theory of complex networks and probabilistic techniques for content mining. At its core there is the idea that nodes in a complex network correspond to basic information units from which links are extracted via methods of machine learning. Hence the links themselves are viewed as emergent properties, similarly to the broader structural properties mentioned above. Indeed, beside rounding up the theory, this approach based on learning has clear practical benefits, in that it makes networks emerge from arbitrary information domains. We provide examples and applications in a variety of contexts, starting from an information-theoretic reconstruction of the well-known distinction between “strong links” and “weak links” and then delving into specific applications such as business process management and analysis of policy making. (shrink)

This paper aims to explore an overlooked aspect of deep-fake technology, specifically its application as a protective tool for concealing the identities of targeted individuals or whistleblowers. Since its emergence in 2017, deep-fakes have been intertwined with various sociotechnical imaginaries. Traditionally, deep-fake technology has been portrayed as a potential threat to privacy and a weapon for disseminating false information, evident from its definitions which emphasize its deceptive nature and malicious use. Moreover, the origins of deepfakes, such as the creation and (...) online distribution of altered pornographic material with harmful intentions, further reinforce this perception. As a result of blurring the boundaries between reality and fiction, truth and falsehood, these synthetic media forms not only pose a risk of disinformation and deception but also offer unexplored avenues for creative expression. Thus, this study examines deep-fake technology as a form of ‘digital camouflage’ by analyzing its usage in David France’s documentary film _Welcome to Chechnya_ (2020). The argument presented in this paper suggests that this illustration challenges the dominant narrative surrounding deep-fakes and highlights an ethical and potentially positive application of this technology. (shrink)

This book is an updated approach to a discipline of special importance in our changing world. It allows a full knowledge from the epistemological and historical basis that allows understanding the discipline from the beginning. The chapters devoted to the analysis of how bioethics is used to analyze complex situations in biomedical fields permits the understanding of its importance to solve them and protecting human beings. One important contribution of the book is looking at current and future challenges that will (...) need an ethical consideration to make sure that biomedical research is not divorced from human rights. (shrink)

Delusion is an exceptional test case for the principal categories of common sense and philosophical thought such as ‘reason’, ‘truth’ and ‘reality’. Via an engagement with the legacy of Freud and the most remarkable results of 20th-century psychiatry, the author’s aim is to analyse the paradoxical forms of delusion and to shed light on the logics that underlie and orient its specific modalities of temporalization, conceptualization and argumentation.

Atran's putative module for folk biology is evaluated with respect to evidence from patients showing category-specific impairments for living kinds. Existing neuropsychological evidence provides no support for the primacy of categorization at the generic species level. We outline reasons for this and emphasize that such claims should be tested using inductive reasoning tasks.

Novelty, the creation of new information, has been the hallmark of Juri M. Lotman’s thought. This issue resurfaces in the discussion of his now famous article “On the semiosphere,” in which Lotman, drawing on Vernadsky, identifies the principles of symmetry, asymmetry, and enantiomorphism as pivotal aspects of the semiotic mechanism of the semiosphere. Specular phenomena and mirror reflections have not only found a prominent place in contemporary semiotic theories of different scholarly traditions – from general semiotics (Eco, Volli) to cognitive (...) semiotics (Sonesson) and to the semiotics of culture (Lotman, Levin) – but they also nail down a key element of the inner mechanism of Lotman’s concept of the semiosphere. By using the analogy of thefacereflecting in amirror, Lotman remarks: “It is also like a face, which, wholly reflected in a mirror, is also reflected in any of its fragments, which, in this form, represents the part and yet remains similar to the whole mirror.” By capitalizing on this excerpt, this study unpacks the significance of Lotman’s idea of specular mechanisms as generators of meaning within the semiosphere. (shrink)

Two hundred years after it was first published, Mary Shelley’s Frankenstein; or, the modern Prometheus remains relevant. This novel has endured because of its literary merits and because its themes lend themselves to analysis from multiple viewpoints. Scholars from many disciplines have examined this work in relation to controversial scientific research. In this paper, we review the academic literature where Frankenstein is used to discuss ethics, bioethics, science, technology and medicine. We searched the academic literature and carried out a content (...) analysis of articles discussing the novel and films derived from it, analyzing the findings qualitatively and quantitatively. We recorded the following variables: year and language of publication, whether it referred to the novel or to a film, the academic discipline in which it was published, and the topics addressed in the analysis. Our findings indicate that the scientific literature on Frankenstein focuses mainly on science and the personality of the scientist rather than on the creature the scientist created or ethical aspects of his research. The scientist’s responsibility is central to the ethical interest of Frankenstein; this issue entails both the motivation underlying the scientist’s acts and the consequences of these acts. (shrink)

The ‘standard picture of meaning’ suggests that natural languages are composed of two different kinds of words: concrete words whose meaning rely on observable properties of external objects and abstract words which are essentially linguistic constructs. In this study, we challenge this picture and support a new view of the nature and composition of abstract concepts suggesting that they also rely to a greater or lesser degree on body-related information. Specifically, we support a version of this new view which we (...) call “x-ception theory” maintaining that abstract concepts are based on internal information of a proprioceptive, interoceptive and affective kind. Secondly, we address a methodological issue concerning the so-called concreteness and imageability measures, two tools that are widely used in (mainly psycholinguistic) empirical research to assess the degree of concreteness of specific words. On the basis of this analysis we argue that—even though the classical concreteness and imageability measures were developed in relation to the standard picture of meaning—they can also be used in the new framework of x-ception theory. In particular, we suggest that the discrepancy between these two measures provides a clue as to whether a word relies on internal information. By contrast, we argue that a new measure for concreteness recently proposed in order to address some problems with the old measure is completely inappropriate for this aim. (shrink)

Perceiving and recognizing others via their faces is of pivotal importance. The ability to perceive others in the environment – to discern between friends and foes, selves and others – as well as to detect and seek to predict their possible moves, plans, and intentions, is a set of skills that has proved to be essential in the evolutionary history of humankind. The aim of this study is to explore the subject of face recognition as a semiotic phenomenon. The scope (...) of this inquiry is limited to face perception by the human species. The human face is analysed on the threshold between biological processes and cultural processes. We argue that the recognition of likenesses has a socio-cultural dimension that should not be overlooked. By drawing on Georg Lichtenberg’s remarks on physiognomy, we discuss the critique of the semiotic bias, the association of ideas, and the mechanism of typification involved in face recognition. Face typification is discussed against the background of face recognition and face identification. We take them as three gradients of meaning that map out a network of relationships concerning different cognitive operations that are at stake when dealing with the recognition of faces. (shrink)

From prehistoric stone tools, to machines, to computers, things have traveled a long road along with human beings. Changing with the times, places, and methods of their production, emerging from diverse histories, and enveloped in multiple layers of meaning, things embody ideas, emotions, and symbols of which we are often unaware. The meaning of "thing" is richer than that of "object," which is something that is manipulated with indifference or according to impersonal technical procedures. Things also differ from merchandise, objects (...) that can be sold or exchanged or seen as status symbols. Things, in the philosophical sense, are nodes of relationships with the life of others, chains of continuity among generations, bridges that connect individual and collective histories, junctions between human civilizations and nature. Things incite us to listen to reality, to make them part of ourselves, giving fresh life to an otherwise suffocating interiority. Things also reveal the hidden aspect of a "subject" in its most secret and least explored side. Things are the repositories of ideas, emotions, and symbols whose meaning we often do not understand. In an unexpected but coherent journey that includes the visions of classic philosophers from Aristotle to Husserl and from Hegel to Heidegger, along with the analysis of works of art, Bodei addresses issues such as fetishism, the memory of things, the emergence of department stores, consumerism, nostalgia for the past, the self-portraits of Rembrandt and Dutch still-lifes of the seventeenth century. The more we are able to recover objects in their wealth of meanings and integrate them into our mental and emotional horizons, he argues, the broader and deeper our world becomes. (shrink)

The present study investigates and thematizes the interrelation between face masking, concealment, and deceit. It starts from the premise that the significance of disguise and deceit in the history of ideas should be reversed as these methods of the management of human appearance are not only regarded as coercive methods to manipulate and exert power over others but also as tactics skillfully used by the weak in order to outmaneuver those who are in a position of power. The study traces (...) the matrix of simulation and dissimulation as forming the structure of deceit, it reviews some of the main theories of disguise within the field of semiotics, and it singles out two main dimensions of disguise, one geared upon dynamism and the other based on the static features of the face. This study suggests that classifications of masks elaborated in semiotic theory hitherto are useful but insufficient to encompass the full scope of such phenomenon. For this reason, the study provides a new typology of masks. (shrink)

C'est un truisme de constater que la déontologie professionnelle des avocats est, depuis une vingtaine d'années environ, en pleine évolution. Il importe de préciser celles des règles qui peuvent légitimement s'adapter aux conceptions du monde moderne et réaffirmer celles qui sont irréductibles car elles constituent la base même de la profession. Me Remo Danovi analyse les diverses facettes de ces changements en mettant bien en lumière ce qui doit demeurer, à travers tout, " la loi d'Antigone ".

This is a comprehensive discussion of complexity as it arises in physical, chemical, and biological systems, as well as in mathematical models of nature. Common features of these apparently unrelated fields are emphasised and incorporated into a uniform mathematical description, with the support of a large number of detailed examples and illustrations. The quantitative study of complexity is a rapidly developing subject with special impact in the fields of physics, mathematics, information science, and biology. Because of the variety of the (...) approaches, no comprehensive discussion has previously been attempted. This book will be of interest to graduate students and researchers in physics (nonlinear dynamics, fluid dynamics, solid-state, cellular automata, stochastic processes, statistical mechanics and thermodynamics), mathematics (dynamical systems, ergodic and probability theory), information and computer science (coding, information theory and algorithmic complexity), electrical engineering and theoretical biology. (shrink)

This paper presents a theoretical investigation of the issue of lying from a semiotic perspective and its specific aim is the analysis of the theory of the lie asconceived by Aurelius Augustinus, bishop of Hippo, also known as Augustine or St. Augustine. The latter devoted two short treatises to the issue oflying: De mendacio and Contra mendacium, written in ca. 395 DC and 420 DC, respectively. Th e paper will focus on duplicity and intention to deceive as fundamental and necessary (...) features of the lie. Augustine’s chief contribution to the study of human deception was to have severed the assessment of what is a lie from factual falsity. For Augustine, at the kernel of the notion of lying lies the idea of intentionality. Following this line of thought, the paper singles out two types of intentionality, namely the intention to assert a falsehood and the intention to mislead. On the basis of this double nature of intentionality, the present paper seeks to outline a theoretical framework for the study of species of falsehoods. The outcome is a typology of untruthfulness that envisages a fourfold inventory of falsehoods based on the difference between jokes, errors, lies and pretences. (shrink)

This paper seeks to shed light on an unwritten chapter in the history of Tartu semiotics, that is, to draw a parallel between Juri Lotman and Emile Benvenisteon the status of natural language among other systems of signs. The tenet that language works as a ‘primary modelling system’ represents one of the trademarksof the Tartu-Moscow school. For Lotman, the primacy assigned to natural language in respect to other systems of signs lied in the fact that the former functions as a (...) ‘model’ for the latter thus regarded as ‘secondary modelling systems’. Yet how does language carry out its function of being a model for other sign systems? Is language the only primary modelling system? This paper seeks to foster the abovementioned claim of the primacy of natural language and argues that this issue deserves a closer inspection. In order to follow this route, it suggests a parallel between Lotman and Benveniste arguing that there exist several points in common that lead to a convergence of positions between these two remarkable scholars. The paper explores such a possibility, arguing that Lotman’s and Benveniste’s positions open up an interesting debate with specific reference to the relations laid down between language and other system of signs. (shrink)