The notion of ubuntu and communalism is of great importance in anAfrican educational discourse, as well as inAfrican Philosophy of Education and in Africanphilosophical discourse. Ubuntu is aphilosophy that promotes the common good ofsociety and includes humanness as an essentialelement of human growth.

How to understand the "entrepreneurial university"? Three hundred years of popularised economic/philosophical thought, in which conflict/competition has been presented as progressive; lacking a normative context, this becomes warlike. Society presented as a "macro-market", linking people with money and media and frowning on political justice, leads to economism (economic totalitarianism). This instrumentalises universities and motivates bookkeeping rationality and goal rationality; the maximisation thesis guides managerial aims. Scholarship becomes industrialised and leadership managerialised. Empty concepts of "quality" and "competitiveness" become audit measures of (...) "excellence"; this is standardised scholarship, serving hedonistic leisure class values and neglecting perspectivised creative, critical involvement with the suffering world. (shrink)

Every year, hundreds of patients in England die whilst waiting for a kidney transplant, and this is evidence that the current system of altruistic-based donation is not sufficient to address the shortage of kidneys available for transplant. To address this problem, we propose a monopsony system whereby kidney donors can opt-in to receive financial compensation, whilst still preserving the right of individuals to donate without receiving any compensation. A monopsony system describes a market structure where there is only one ‘buyer’—in (...) this case the National Health Service. By doing so, several hundred lives could be saved each year in England, wait times for a kidney transplant could be significantly reduced, and it would lessen the burden on dialysis services. Furthermore, compensation would help alleviate the common disincentives to living kidney donation, such as its potential associated health and psychological costs, and it would also help to increase awareness of living kidney donation. The proposed system would also result in significant cost savings that could then be redirected towards preventing kidney disease and reducing health disparities. While concerns about exploitation, coercion, and the ‘crowding out’ of altruistic donors exist, we believe that careful implementation can mitigate these issues. Therefore, we recommend piloting financial compensation for living kidney donors at a transplant centre in England. (shrink)

In this incisive and thought-provoking book, Francois Venter illuminates the issues arising from the fact that the current language of constitutional law is strongly premised on a particular worldview rooted in the history of the states around the North Atlantic Ocean. Highlighting how this terminological hegemony is being challenged from various directions, Venter explores the problem that all constitutional comparatists face: that they all must use the same words to express different meanings. Offering a compact but comprehensive constitutional (...) history, Venter investigates the ways in which the standard vocabulary does not fit comfortably in many contemporary constitutional orders, as well as examining how its cogency is increasingly being questioned. Chapters contextualize comparative constitutional methods to demonstrate how the language choices made by comparatists are shaped by their own perspectives, arguing that careful explanation of the meanings attached to constitutional terms is imperative in order to be persuasive or even understood. Tackling the foundational elements of the field, this book will be a critical read for constitutional scholars across the globe. It will also be of interest to high-level practitioners of constitutional law and political scientists for its investigation of terminology that is crucial to their work. (shrink)

Predictive processing is often presented as a unifying framework for perception, action, and cognition, being able to explain most mental phenomena : with regard to perception, the brain harbours a generative model issuing top-down expectations that are matched against bottom-up sensory feedback. Mismatches lead to error messages and model updates until the brain is 'getting it right'. The core notion of prediction error minimization commits the framework to a specification of accuracy conditions. We therefore turn to issues related to the (...) determination of satisfaction conditions discussed in the philosophy of perception. In particular, we rely on work by Recanati who shows that the accuracy conditions of perceptual content are partly determined by the intentional mode and the perceiver. It is important to notice that the self can enter the specification of accuracy conditions in two ways, namely as subject or as object. Even if we do not perceive ourselves explicitly as an object, we always implicitly represent ourselves as subject. We discuss whether and how these two ways of self-representation can be respected in the predictive processing framework. (shrink)

The purpose of this study was to ascertain South African Small, Medium and Micro Enterprise owners'/managers' perceptions regarding the importance of corporate social responsibility in this sector of the economy. Their views were gauged by means of a questionnaire based on Carroll's CSR hierarchy. Descriptive and inferential statistics, based on 262 questionnaires, show that SMME owners/managers viewed CSR as a very important business practice in South Africa. Given the critical role that SMMEs can play in addressing South Africa's socio-economic needs, (...) it is recommended that more SMME owners/managers be educated as to what CSR entails and how it can be implemented. (shrink)

In this paper, I argue for an embodied, embedded approach to predictive processing and thus align the framework with situated cognition. The recent popularity of theories conceiving of the brain as a predictive organ has given rise to two broad camps in the literature that I call free energy enactivism and cognitivist predictive processing. The two approaches vary in scope and methodology. The scope of cognitivist predictive processing is narrow and restricts cognition to brain processes and structures; it does not (...) consider the body-beyond-brain and the environment as constituents of cognitive processes. Free energy enactivism, on the other hand, includes all self-organizing systems that minimize free energy and thus does not offer any unique explanations for more complex cognitive phenomena that are unique to human cognition. Furthermore, because of its strong commitment to the mind-life continuity thesis, it does not provide an explanation of what distinguishes more sophisticated cognitive systems from simple systems. The account that I develop in this paper rejects both of these radical extremes. Instead, I propose a compromise that highlights the necessary components of predictive processing by making use of a mechanistic methodology of explanation. The starting point of the argument in this paper is that despite the interchangeable use of the terms, prediction error minimization and the free energy principle are not identical. But this distinction does not need to disrupt the status quo of the literature if we consider an alternative approach: Embodied, Embedded Predictive Processing. EEPP accommodates the free energy principle, as argued for by free energy enactivism, but it also allows for mental representations in its explanation of cognition. Furthermore, EEPP explains how prediction error minimization is realized but, unlike cognitivist PP, it allocates a constitutive role to the body in cognition. Despite highlighting concerns regarding cognitivist PP, I do not wish to discredit the role of the neural domain or representations as free energy enactivism does. Neural structures and processes undeniably contribute to the minimization of prediction error but the role of the body is equally important. On my account, prediction error minimization and free energy minimization are deeply dependent on the body of an agent, such that the body-beyond-brain plays a constitutive role in cognitive processing. I suggest that the body plays three constitutive roles in prediction error minimization: The body regulates cognitive activity, ensuring that cognition and action are intricately linked. The body acts as distributor in the sense that it carries some of the cognitive load by fulfilling the function of minimizing prediction error. Finally, the body serves to constrain the information that is processed by an agent. In fulfilling these three roles, the agent and environment enter into a bidirectional relation through influencing and modeling the structure of the other. This connects EEPP to the free energy principle because the whole embodied agent minimizes free energy in virtue of being a model of its econiche. This grants the body a constitutive role as part of the collection of mechanisms that minimize prediction error and free energy. The body can only fulfill its role when embedded in an environment, of which it is a model. In this sense, EEPP offers the most promising alternative to cognitivist predictive processing and free energy enactivism. (shrink)

The last few years have seen dramatic progress in the development of HIV pre-exposure prophylaxis (PrEP). These developments have been met by ethical concerns. HIV interventions are often thought to be ethically difficult. In a context which includes disagreements over human rights, controversies over testing policies, and questions about sexual morality and individual responsibility, PrEP has been seen as an ethically complex intervention. We argue that this is mistaken, and that in fact, PrEP does not raise new ethical concerns. Some (...) of the questions posed by PrEP are not specific to HIV prophylaxis, but simply standard public health considerations about resource allocation and striking a balance between individual benefit and public good. We consider sexual disinhibition in the context of private prescriptions, and conclude that only unjustified AIDS-exceptionalism or inappropriate moralism about sex supports thinking that PrEP raises new ethical problems. This negative conclusion is significant in a context where supposed ethical concerns about PrEP have been raised, and in the context of HIV exceptionalism. (shrink)

We have synthesized a 582,970-base pair Mycoplasma genitalium genome. This synthetic genome, named M. genitalium JCVI-1.0, contains all the genes of wild-type M. genitalium G37 except MG408, which was disrupted by an antibiotic marker to block pathogenicity and to allow for selection. To identify the genome as synthetic, we inserted "watermarks" at intergenic sites known to tolerate transposon insertions. Overlapping "cassettes" of 5 to 7 kilobases (kb), assembled from chemically synthesized oligonucleotides, were joined by in vitro recombination to produce intermediate (...) assemblies of approximately 24 kb, 72 kb ("1/8 genome"), and 144 kb ("1/4 genome"), which were all cloned as bacterial artificial chromosomes in Escherichia coli. Most of these intermediate clones were sequenced, and clones of all four 1/4 genomes with the correct sequence were identified. The complete synthetic genome was assembled by transformation-associated recombination cloning in the yeast Saccharomyces cerevisiae, then isolated and sequenced. A clone with the correct sequence was identified. The methods described here will be generally useful for constructing large DNA molecules from chemically synthesized pieces and also from combinations of natural and synthetic DNA segments. 10.1126/science.1151721. (shrink)

Mani lived in a world where many ideas contributed to his unique theology. In the scriptural legacy of Mani seven of his books show influence of Ethiopian Enoch. These books are identified in this article and the use of Enochic material in those books is discussed. The Manichaean myth is briefly discussed and used to propose that Enochic influence can mainly be found in the way First Enoch depicted characters and presented the cosmos. Mani adopted his ideas mainly from the (...) Book of the Watchers , the Book of Parables and the Astronomical Book of Enoch where evil beings and cursed places are depicted. (shrink)

In the article “Fifty Years of U.S. Mass Incarceration and What It Means for Bioethics,” Sean Valles provides an important reminder of the consequences of mass incarceration in the United States and identifies potential roles for bioethicists in addressing this system. My limited view—that of a physician who conducts court‐ordered investigations and monitoring of health services behind bars—is that the ongoing failure of most academic and professional organizations to be more effective in this much‐ignored area stems from the lack of (...) leaders and staff who have been directly impacted by mass incarceration. As conditions behind bars worsen, and a new war on drugs recoils the spring of mass incarceration, there is a pressing need to train, recruit, and promote people who know the realities of the criminal (and immigration) justice system and its impact on health and well‐being. This step can bring a more powerful engagement of bioethics regarding housing, employment, and health care and policing, as well as the numerous and harmful elements of jails, prisons, and detention settings. I provide examples of partners I learn from in this arena, as well as some discrete and technical areas for possible investigation. (shrink)

In February 2022, the Court of Protection was faced with the question of whether a kidney transplant was in the best interests of William Verden. The case highlighted the legal, ethical and clinical complexities of treating potential kidney transplant patients with impaired decision-making. Above all, it exposed the potential risk of discrimination on the basis of disability when treatment decisions in relation to potential kidney recipients with impaired capacity are being made. In this paper, we draw on the Verden case (...) to (1) examine the role of the Court of Protection in cases relating to patients with impaired decision-making capacity who require a transplant, (2) to highlight the lack of empirical data on patients who have faced inequitable access to transplant and (3) highlight the shortcomings of the existing legal and regulatory framework in England and Wales guiding clinical decision making for patients in William’s position. We consequently argue that there is a clear need for action to ensure equitable access to transplant for those in William’s position. Furthermore, we suggest that there is a responsibility incumbent on policy makers and clinicians alike to develop a meaningful, and meaningfully operational, framework centred on preventing discrimination against potential organ recipients based on their decision-making capacity. (shrink)

This article uses cognitive linguistics and an embodied cognitive approach to analyse the passage of Proverbs 1:20-33. The poem, presented as a prophetic threat, uses metaphoric language to depict the dialogue between personified wisdom and metaphorised human beings. The analysis indicates that there is a coherence of metaphors in the target domain shared by both metaphorised source domains of wisdom and the hearers. Using bodily metaphors it stresses the need of wisdom to be internalised by men.

Spirituality and ultimacy are inextricably linked. Underlying the plurality of spiritualities are myriad ways to construe the identity of the transcendent. In a Christian sense, the notion of the divine with a Trinitarian identification is central. The article examines the implications of such a naming of God for spirituality. Attention is paid to the relationship between doctrinal theology and spirituality as well as to scholarly reflection already undertaken on a so-called Trinitarian spirituality. The article suggests guidelines for future work and (...) emphasises that an adequate account should be given of how Trinitarian theology is undertaken as symbolising and hermeneutical endeavour. Some unique features of this spirituality are profiled, and it is argued that a Trinitarian imagining of the divine may generate perspectives not possible in an unqualified monotheistic approach. (shrink)