Abstract:This paper considers the relevance of the concept of “eugenics,”—a term associated with some of the most egregious crimes of the twentieth century—to the possibility of editing human genomes. The author identifies some uses of gene editing as eugenics but proposes that this identification does not suffice to condemn them. He proposes that we should distinguish between “morally wrong” practices, which should be condemned, and “morally problematic” practices that call for solutions, and he suggests that eugenic uses of gene editing (...) fall into this latter category. Although when we choose the characteristics of future people we are engaging in morally dangerous acts, some interventions in human heredity should nevertheless be acknowledged as morally good. These morally good eugenic interventions include some uses of preimplantation genetic diagnosis. The author argues that we should think about eugenic interventions in the same way that we think about morally problematic interventions in public health. When we recognize some uses of gene editing as eugenics, we make the dangers of selecting or modifying human genetic material explicit. (shrink)

Comparing the ways in which the French cultural theorist Paul Virilio and the Australian cybernetic performance artist Stelarc criticize or defend technological cultural practices, this article argues that Virilio's ambiguous responses to avant-garde art highlight his key ideas far move clearly than his single-minded critique of 'termninal' mass-cultural practices - without any relationship to art - in Polar Inertia and Open Sky. Virlio's The Art of the Motor attacks the strategies of 20th-century technological avant- gardes for their apparent eugenicist and (...) fascist sympathies, but Virilios more recent interviews in Cyberrnonde and Voage d'hiver defend the ways in which the pre-technological avant-gardes resist the realist perspective of photography, and argue that the technological arts should offer similar resistance to the impact of cyberculture. Whereas Virilio concludes that such technological 'resistance' is probably impossible, Stelarc's recent research identifies exceptions to Virilio's rules. (shrink)

This paper defends the idea that there might be vagueness or indeterminacy in the world itself---as opposed to merely in our representations of the world---against the charges of incoherence and unintelligibility. First we consider the idea that the world might contain vague *properties and relations*; we show that this idea is already implied by certain well-understood views concerning the semantics of vague predicates (most notably the fuzzy view). Next we consider the idea that the world might contain vague *objects*; we (...) argue that an object is indeterminate in a certain respect (colour, size, etc.) just in case it is a borderline case of a maximally specific colour (size, etc.) property. Finally we consider the idea that the *world as a whole* might be indeterminate; we argue that the world is indeterminate just in case it lacks a determinate division into determinate objects. (shrink)

1. Introduction 2. Reward-Guided Decision Making 3. Content in the Model 4. How to Deflate a Metarepresentational Reading Proust and Carruthers on metacognitive feelings 5. A Deflationary Treatment of RPEs? 5.1 Dispensing with prediction errors 5.2 What is use of the RPE focused on? 5.3 Alternative explanations—worldly correlates 5.4 Contrast cases 6. Conclusion Appendix: Temporal Difference Learning Algorithms.

The distinction between literal and figurative use is well-known and embedded in ‘folk linguistics’. According to folk linguistics, figurative uses deviate from literal ones. But recent work on lexical modulation and polysemy shows that meaning deviation is ubiquitous, even in cases of literal use. Hence, it has been argued, the literal/figurative distinction has no value for theorising about communication. In this paper, we focus on metaphor and argue that here the literal–figurative distinction has theoretical importance. The distinction between literal and (...) metaphorical needs to be captured by our account of communication because literal uses transmit information in a way that metaphorical ones do not. We argue that there is a way to explain the literal/metaphorical distinction that preserves the core of the folk-linguistic idea and gives the distinction theoretical relevance. We propose that literal uses of a word are made with the intention to conform to an established practice of use, while metaphorical uses do not so conform, but depend on this pre-existing practice. Our account can deal with data that are problematic for other theories. A further advantage is that it extends naturally to other non-literal uses of words, including metonymy. (shrink)

There is a debate about the possibility of mind-uploading – a process that purportedly transfers human minds and therefore human identities into computers. This paper bypasses the debate about the metaphysics of mind-uploading to address the rationality of submitting yourself to it. I argue that an ineliminable risk that mind-uploading will fail makes it prudentially irrational for humans to undergo it.

Postmodernism and poststructuralism challenge fundamental positions in social theory. This book sets out some of the components of a postmodern social theory of health and healing, deriving from theorists including Derrida, Deleuze and Guattari, Foucault, Cixous and Kristeva. Nicholas J. Fox observes that the knowledge of the medical profession about the body, illness and health supplies the basis for medical dominance. The body of the patient is inscribed by discourses of professional `care,' an interaction which subjectifies the patient. Fox (...) explores the character of this power - and how it may be, and is, resisted. The book illustrates with detailed examples how the organization of health care and the caring relationship itself are sites for this contestation of power. Elements of feminist theory, and Derridean concepts of diffrance and intertextuality, supply the framework for the politics and ethics of the postmodern position on health. Deleuze and Guattari's radical challenge to psychoanalysis and familial repetitions within the healer/patient contact allows a re-reading of central ideas in medical sociology. While focusing upon the possibilities of postmodern social theory, the book demands a reappraisal of issues of structure, identity and knowledge in modernist medical sociology. Modernist sociology, Fox suggests, has been complicit in the creation of `the patient,' and of 'health' and 'illness.' Written with an emphasis on accessibility, this book explores the practical consequences of postmodern theory as well as familiarizing the reader with the concepts of postmodernism. (shrink)

This article provides a speech act analysis of ‘crime-enacting’ provisions in criminal statutes, focusing on the illocutionary force of these provisions. These provisions commonly set out not only particular crimes and their characteristics but also their associated penalties. Enactment of a statute brings into force new social facts, typically norms, through the official utterance of linguistic material. These norms are supposed to guide behaviour: they tell us what we must, may, or must not do. Our main claim is that the (...) illocutionary force of such provisions is primarily ‘world-creating’, i.e. effective, or declarational, rather than directive. We assume that directive illocutionary force is either direct or indirect, showing that provisions need not contain the linguistic items that make for direct directives and that according to standard tests no indirect directive is present. A potential counter-argument is that any utterance serving to direct behaviour is necessarily a directive. We show that this behaviour-directing property is shared by some clear non-directives. (shrink)

Economics takes an individualistic approach to human behaviour. This is reflected in the use of 'contingent valuation' surveys to conduct cost benefit analysis for economic policy evaluation. An individual's valuation of a policy is assumed to be unaffected by the burdens it places on others. We report a survey experiment to test this supposition in the context of climate change policy. Willingness to pay for climate change mitigation was higher when richer individuals were to bear higher costs than when, as (...) is usual, no explicit information was provided about cost distribution. This result is inconsistent with the usual interpretation of contingent valuation data. It also suggests that the data may be biased indicators of policy acceptance. Additional survey questions suggest that a collective mode of reasoning is common. (shrink)

A common theme in the historiography of Greek ethics says that modern ethics is characterized by imperative notions such as ‘duty’—and with a Judeo‐Christian notion of imperatives or commands issued by god—whereas ancient ethics supposedly deals mainly with ‘attractive notions such as ‘good’ and ‘virtue’. This thought is often juxtaposed with the idea that imperative notions betoken a conflict between one's duty and one's good, because an imperative seems to be required only to command people to do what they do (...) not wish to do, which is felt to be inappropriate to the supposed eudaimonism of Greek ethics. In fact Greek ethics makes substantial use of imperative notions, and does not attempt to show that attractive notions are more basic or preferable in ethics. (shrink)

Thus far it has been shown that Greek ethics is not as different from modern ethics as is commonly held, and that we cannot oppose a harmonizing Greek ethical outlook with a modern view that involves a conflict between happiness and adherence to ethical standards. Greek ethics has universalistic features—though they are different from the egalitarian characteristics of modern positions and do not focus on the notion of benevolence in the way that modern ethics does—and it mostly distinguishes self‐referential and (...) non‐self‐referential aims. Moreover, there is not in any case such a thing as a monolithic ethical view of ‘the Greeks’, and the idea of a straightforward contrast between ‘ancient’ and ‘modern’ ethics is best avoided. (shrink)

One of the main vehicles for the reconciliation of individual and social happiness that has supposedly been characteristic of Greek ethics is the concept of the polis. In the Hegelian tradition it has been thought that the Greeks reduced all norms and values to standards laid down by and for the city‐state, and that this fact made it possible for them to hold that the well‐being of an individual is entirely compatible with the well‐being of his fellow‐citizens and of the (...) city‐state as a whole. However, the Greeks were familiar with and attached substantial weight to non‐polis‐based norms and values, even universalist ones like the Golden Rule, and made ample conceptual room for conflict between the happiness of a citizen and that of his community. Moreover, Greek attitudes on this issue were variegated, not uniform. (shrink)

This introductory article is structured around the following themes: it begins with a brief overview of some important works that have paved the way for the present discussion. This is followed by a critique of the concept of “experience” and the philosophies based on it, that was first presented by feminist thinkers Joan Scott and Judith Butler in the 1980’s. The question this debate poses to the discussions in this book is whether focusing on experience is still a philosophically viable (...) option. After that, the views of Edmund Husserl – often described as “the father of phenomenology” – are presented on the particular themes of motherhood and pregnancy, as it is often overlooked that he had anything to say on the topic. Then follows a short outline of the structure of the experience of pregnancy, and also the modest suggestion that pregnancy should be seen not only as “split subjectivity” but also as a specific mode of phenomenological “in-between.” Thereafter the question is taken up whether pregnancy as a philosophical topic might also affect the methodological core of phenomenology. The article ends with a speculative outlook towards certain themes that have developed as a consequence of thinking pregnancy philosophically. (shrink)

This book advocates a radical shift of concern in philosophical, historical, and sociological studies of the sciences, and explores the consequences of such a shift. The historically-oriented first part of the work deals with the ways in which ranges of questions become real and cease to be real for communities of inquirers. The more philosophically-oriented second part of the work introduces the notion of absolute reality of questions, and addresses doubt about the claims of the sciences to have accumulated absolutely (...) real questions. It is argued that recent studies in the sociology and social history of the science pose strong challenges to the sciences by revealing how appeals to authority, vested interests, and rhetorical and aesthetic sensibilities play substantial roles in the practices of the sciences. The final chapter defends the pragmatic stance of the work, and of its companion, The Fortunes of Inquiry, and draws morals about the roles of criticism and reflection in the philosophy of science and in the sciences themselves. (shrink)

A clearly written, authoritative introduction to Taylor's work.

Aesthesis, the classical term for sensing and perceiving, is at the heart of innumerable problems that plague global society. The purpose of this article is to open a conversation on aesthesis. We survey the roots and relevance of aesthesis as a direct albeit contested relation and engagement with the world and with Others. From its pre-Socratic origins, aesthesis has been both a pragmatic, somatic concept, prompting a re-evaluation of the distinction between experience and abstraction. We trace its ongoing repression from (...) Plato through ‘western’ theories of formal Aesthetics. Drawing on a relational interpretation of Protagoras’ aesthesis, we argue that modern pragmatists and radical empiricists, as well as more contemporary critics of the ‘colonization’ of aesthesis (Mignolo and Vasquez) by formal Aesthetics recognize and develop the relational and ethical aspects of aesthesis. We consider the role of the body, affect, and of the intangible or virtual qualities of aesthesis. The ethics of obligations (Weil) in the polis (Arendt) shows how aesthesis informs politics despite its repression in favour of moral and legal norms. We argue this is relevant to contemporary crises such as xenophobia and ecocidal climate warming. (shrink)

There is increasing evidence for epigenetically mediated transgenerational inheritance across taxa. However, the evolutionary implications of such alternative mechanisms of inheritance remain unclear. Herein, we show that epigenetic mechanisms can serve two fundamentally different functions in transgenerational inheritance: (i) selection-based effects, which carry adaptive information in virtue of selection over many generations of reliable transmission; and (ii) detection-based effects, which are a transgenerational form of adaptive phenotypic plasticity. The two functions interact differently with a third form of epigenetic information transmission, (...) namely information about cell state transmitted for somatic cell heredity in multicellular organisms. Selection-based epigenetic information is more likely to conflict with somatic cell inheritance than is detection-based epigenetic information. Consequently, the evolutionary implications of epigenetic mechanisms are different for unicellular and multicellular organisms, which underscores the conceptual and empirical importance of distinguishing between these two different forms of transgenerational epigenetic effect. (shrink)

Fodor’s radical concept nativism flowed from his view that hypothesis testing is the only route to concept acquisition. Many have successfully objected to the overly-narrow restriction to learning by hypothesis testing. Existing representations can be connected to a new representational vehicle so as to constitute a sustaining mechanism for a new representation, without the new representation thereby being constituted by or structured out of the old. This paper argues that there is also a deeper objection. Connectionism shows that a more (...) fundamental assumption underpinning the debate can also be rejected: the assumption that the development of a new representation must be explained in content-involving terms if innateness is to be avoided. -/- Fodor has argued that connectionism offers no new resources to explain concept acquisition: unless it is merely an uninteresting claim about neural implementation, connectionism’s defining commitment to distributed representations reduces to the claim that some representations are structured out of others (which is the old, problematic research programme). Examination of examples of representational development in connectionist networks shows, however, that some such models explain the development of new representational capacities in non-representational terms. They illustrate the possibility of representational development that is not explicable-by-content. Connectionist representations can be distributed in an important sense, which is incompatible with the assumption of explanation-by-content: they can be distributed over non-representational resources that account for their development. Rejecting the assumption of explanation-by-content thereby opens up a more radical way of rejecting Fodor’s argument for radical concept nativism. (shrink)

This paper advocates explicitness about the type of entity to be considered as content- bearing in connectionist systems; it makes a positive proposal about how vehicles of content should be individuated; and it deploys that proposal to argue in favour of representation in connectionist systems. The proposal is that the vehicles of content in some connectionist systems are clusters in the state space of a hidden layer. Attributing content to such vehicles is required to vindicate the standard explanation for some (...) classificatory networks’ ability to generalise to novel samples their correct classification of the samples on which they were trained. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:On the Inconvenience of Other People by Lauren BerlantNicholas AdlerBerlant, Lauren. On the Inconvenience of Other People. Duke University Press, 2022. 256pp.An Ambivalent TriumphAttachment is a double-edged sword. This idea is the scaffolding of the late Lauren Berlant's pivotal work, Cruel Optimism (2011), which explores the idea that attachment to a collectively invested fantasy of "the good life" acts in disservice of personal growth and lasting fulfillment. The (...) Inconvenience of Other People ostensibly repeats this structure while reattributing the role of fantasy. The premise here is that attachments to other people act in disservice to the fantasy of personal sovereignty. Of course, both texts argue for collectivity and for a recasting of the ordinary that structures current fantasies. But while Cruel Optimism builds around the unavoidable condition of fantasy, Inconvenience takes relations within the present as its fundamentally unavoidable condition, specifically the drive to be in relation even though such relations are inconvenient. "People" in the work's title stands for any attachment, any person or thing to which we exist in relation. To be part of the world is to be constantly taking in and living with the objects around us. This constant process of adjustment generates constant friction with our fantasy of sovereignty, or control, over ourselves. In Berlant's words, "inconvenience is another way of pointing to the experience of nonsovereign relationality," making our inconvenience drive the urge to maintain and explore those nonsovereign relations despite the uncomfortable friction they produce (18). Berlant's final monograph investigates the complexities of living with that inconvenience as well the potential for "loosening [those inconvenient objects] and becoming loose with them" in order to make that inconvenience generative of new perspectives and approaches (150).The prospect of overhauling our relationship with inconvenience takes place on multiple registers, both in terms of the affective states that guide the experience of inconvenience and the frameworks that determine its expression in the world. Refiguring ambivalence and dissociation, [End Page 123] the traditional affective responses to inconvenience, as well as offering a more dynamic structure for engaging with inconvenience than that of the institution, Berlant demonstrates—in a contained and structured way—the very object-loosening for which the text advocates. Although the book is presented as a collection of "assays...clusters of actions that become forms of life that shift the pressures of being in relation," it is nonetheless broken into three distinct chapters that focus on the role of the inconvenient in political relations, sexual relations, and relations with the self (11). These chapters, respectively, take up the inconvenient with regard to infrastructure, ambivalence, and dissociation.To productively engage with inconvenience, it must be accommodated within a social infrastructure. The term infrastructure positions the material of lived relationality as more flexible than that of institutions and more legible than that of expressive causality. For Berlant, "infrastructures are productive, durationally extensive spaces for the pliable forms of life that people use to make rules and norms and other means of extending the world" (23). In Chapter 2, they invoke the concept of the commons, "an orientation toward life and value unbound by concepts of property as constituted by division and ownership," using it as a way to illustrate infrastructuralism in effect (82). The commons can refer to as concrete a physical space as the Boston Common, as explored through Ralph Waldo Emerson's "Nature," or as abstract an inheritance as shared language, as explored through Juliana Spahr's lyrical autobiography, The Transformation (2007).The commons of both Emerson and Spahr make use of the concept of analogy. For Emerson, it stands for "the separation within the nonsovereign relation [of the commons] that makes linking possible" (Berlant 94). Spahr takes a more critical approach, continuing Emerson's use of the term while shining light on the glitches that emerge when any analogy is examined too closely. Acknowledging the rhetorical gymnastics required to "figure equally valued social being" within "imperialist capitalist infrastructures" reveals every possible analogy as both grossly oversimplifying and only temporarily comprehensible (105). Objects within these commons are constantly adjusting and generating new relations. The sense of an ongoing dynamic is what Berlant hopes this... (shrink)

The question of whether non-human animals are conscious is of fundamental importance. There are already good reasons to think that many are, based on evolutionary continuity and other considerations. However, the hypothesis is notoriously resistant to direct empirical test. Numerous studies have shown behaviour in animals analogous to consciously-produced human behaviour. Fewer probe whether the same mechanisms are in use. One promising line of evidence about consciousness in other animals derives from experiments on metamemory. A study by Hampton (Proc Natl (...) Acad Sci USA 98(9):5359–5362, 2001 ) suggests that at least one rhesus macaque can use metamemory to predict whether it would itself succeed on a delayed matching-to-sample task. Since it is not plausible that mere meta-representation requires consciousness, Hampton’s study invites an important question: what kind of metamemory is good evidence for consciousness? This paper argues that if it were found that an animal had a memory trace which allowed it to use information about a past perceptual stimulus to inform a range of different behaviours, that would indeed be good evidence that the animal was conscious. That functional characterisation can be tested by investigating whether successful performance on one metamemory task transfers to a range of new tasks. The paper goes on to argue that thinking about animal consciousness in this way helps in formulating a more precise functional characterisation of the mechanisms of conscious awareness. (shrink)

The purpose of this paper is to confront a well-known problem in interreligious engagement in European institutions, namely the tendency to exclude contributions that do not conform to certain European expectations. It diagnoses problems produced not only by the problem but by certain solutions to it, and to propose in outline an alternative approach. Chief among these problems is the imperative that members of traditions articulate their deepest moral commitments, in order to secure a common moral ground. This imperative has (...) the unintended but drastic effect of excluding important voices in dialogue. Drawing on the figures of Cordelia (in Shakespeare’s King Lear) and Antigone (in Sophocles’ Antigone) it is argued that forced articulation distorts its objects. The theoretical framework of discussion is drawn from Hegel, Schelling, and Adorno as in interpreted by Alasdair MacIntyre, Charles Taylor, and Andrew Bowie. The originality of the argument is the use of aesthetic theory in German philosophy to inform a critique of attempts to make morality central to interreligious engagement. (shrink)

This chapter contains section titled: A Moral and Developmental Parity of Genes and Environment Manufacturing Humans Enhancement and Bad Parenting The Limited Powers of Genetic Engineers Are Enhancements Problematic because they are Positionally Valuable? Regulating the Pursuit of Positional Value.

Theoretical reason, modifiers and probability.

Proper conduct of an AIDS vaccine trial in Africa must be informed not only by the epidemiology and biology of HIV infection in African settings, but also by the ethical norms and cultural constraints prevailing in African settings.

Humans have a much longer juvenile period (weaning to first reproduction, 14 or more years) than their closest relatives (chimpanzees, 8 years). Three explanations are prominent in the literature. (a) Humans need the extra time to learn their complex subsistence techniques. (b) Among mammals, since length of the juvenile period bears a constant relationship to adult lifespan, the human juvenile period is just as expected. We therefore only need to explain the elongated adult lifespan, which can be explained by the (...) opportunity for older individuals to increase their fitness by providing for grandchildren. (c) The recent model by Kaplan and colleagues suggests that longevity and investment in "embodied capital" will coevolve, and that the need to learn subsistence technology contributed to selection for our extended lifespan.We report experiments designed to test the first explanation: human subsistence technology takes many years to learn, and spending more time learning it gives reproductive benefits that outweight lost time. Taking away some of this time should lead to deficits in efficiency. We paid Hadza foragers to participate in tests of important subsistence skills. We compared efficiency of males and females at digging tubers. They differ greatly in time spent practicing digging but show no difference in efficiency. Children who lost "bush experience" by spending years in boarding school performed no worse at digging tubers or target archery than those who had spent their entire lives in the bush. Climbing baobab trees, an important and dangerous skill, showed no change with age among those who attempted it. We could show no effects of practice time.These findings do not support what we label "the practice theory," but we discuss ways in which the theory could be defended; for example, some as-yet-untested skill may be greatly impaired by loss of a few years of the juvenile period. Our data also show that it is not safe to assume that increases in skill with age are entirely due to learning or practice; they may instead be due to increases in size and strength. (shrink)