The social and cognitive science replication crisis is partly due to the limitations of commonly used statistical tools. Inferential statistics require that unsystematic measurement variation is independent of system history, and weak relative to systematic or causal sources of variation. However, contemporary systems research underscores the dynamic, adaptive nature of social, cognitive, and behavioral systems. Variation in human activity includes the influences of intrinsic dynamics intertwined with changing contextual circumstances. Conventional inferential techniques presume milder forms of variability, such as (...) unsystematic measurement error, as in a Gaussian distribution. Inferential statistics indicate an elementary Newtonian cause-effect metaphor for change that is inconsistent with known principles of change in complex systems. Pattern formation in self-organizing systems and quantum probability are used to illustrate theoretical metaphors that instantiate alternative notions of change in complex systems. Inferential statistics and related techniques are crucial scientific resources. However, in the social and behavioral sciences, they must be practiced in conjunction with an appropriate general systems framework that accommodates intrinsic fluctuations and contextual adaptation. (shrink)

The human brain’s ongoing activity is characterized by intrinsic networks of coherent fluctuations, measured for example with correlated functional magnetic resonance imaging signals. So far, however, the brain processes underlying this ongoing blood oxygenation level dependent (BOLD) signal orchestration and their direct relevance for human behavior are not sufficiently understood. In this study, we address the question of whether and how ongoing BOLD activity within intrinsic occipital networks impacts on conscious visual perception. To this end, backwardly masked (...) targets were presented in participants’ left visual field only, leaving the ipsi-lateral occipital areas entirely free from direct effects of task throughout the experiment. Signal time courses of ipsi-lateral BOLD fluctuations in visual areas V1 and V2 were then used as proxies for the ongoing contra-lateral BOLD activity within the bilateral networks. Magnitude and phase of these fluctuations were compared in trials with and without conscious visual perception, operationalized by means of subjective confidence ratings. Our results show that ipsilateral BOLD magnitudes in V1 were significantly higher at times of peak response when the target was perceived consciously. A significant difference between conscious and non-conscious perception with regard to the pre-target phase of an intrinsic-frequency regime suggests that ongoing V1 fluctuations exert a decisive impact on the access to consciousness already before stimulation. Both effects were absent in V2. These results thus support the notion that ongoing slow BOLD activity within intrinsic networks covering V1 represents localized processes that modulate the degree of readiness for the emergence of visual consciousness. (shrink)

The hypothesis of extended cognition (HEC) has been criticized as committing what is called the coupling?constitution fallacy, but it is the critic's use of this concept which is fallacious. It is true that there is no reason to deny that the line between the self and the world should be drawn at the skull and/or the skin. But the data used to support HEC reveal that there was never a good enough reason to draw the line there in the first (...) place. The burden of proof has fallen on the mind?brain identity theory, now that our intuitions/prejudices no longer support it. One of those ?intuitions? is the Aristotelian assumption that the world can be neatly divided into objects that possess intrinsic causal powers, and the causal relations that connect those objects. In modern science, however, the concept of intrinsic causal powers is only a temporary stopgap that makes it possible to begin research in a particular area. It therefore seems best to assume that the line between mind and world is both pragmatic and dynamic. Consequently, the mind might best described as a fluctuating field, rather than an object or structure. (shrink)

Protein structure is dynamic: the intrinsic flexibility of polypeptides facilitates a range of conformational fluctuations, and individual protein chains can assemble into complexes. Proteins are also dynamic in evolution: significant variations in secondary, tertiary and quaternary structure can be observed among divergent members of a protein family. Recent work has highlighted intriguing similarities between these structural and evolutionary dynamics occurring at various levels. Here we review evidence showing how evolutionary changes in protein sequence and structure are often closely (...) related to local protein flexibility and disorder, large‐scale motions and quaternary structure assembly. We suggest that these correspondences can be largely explained by neutral evolution, while deviations between structural and evolutionary dynamics can provide valuable functional insights. Finally, we address future prospects for the field and practical applications that arise from a deeper understanding of the intimate relationship between protein structure, dynamics, function and evolution. (shrink)

Objectives: Autism spectrum disorder (ASD) is a juvenile onset neurodevelopmental disorder with social impairment and stereotyped behavior as the main symptoms. Unaffected relatives may also exhibit similar ASD features due to genetic factors. Although previous studies have demonstrated atypical brain morphological features as well as task-state brain function abnormalities in unaffected parents with ASD children, it remains unclear the pattern of brain function in the resting state.Methods: A total of 42 unaffected parents of ASD children (pASD) and 39 age-, sex-, (...) and handedness-matched controls were enrolled. Multiple resting-state fMRI (rsfMRI) analyzing methods were applied, including amplitude of low-frequency fluctuation (ALFF), regional homogeneity (ReHo), degree centrality (DC), and functional connectivity (FC), to reveal the functional abnormalities of unaffected parents in ASD-related brain regions. Spearman Rho correlation analysis between imaging metric values and the severity of ASD traits were evaluated as well.Results: ALFF, ReHo, and DC methods all revealed abnormal brain regions in the pASD group, such as the left medial orbitofrontal cortex (mOFC) and rectal gyrus (ROI-1), bilateral supplementary motor area (ROI-2), right caudate nucleus head and right amygdala/para-hippocampal gyrus (ROI-3). FC decreasing was observed between ROI-1 and right anterior cingulate cortex (ACC), ROI-2, and bilateral precuneus. FC enhancing was observed between ROI-3 and right anterior cerebellar lobe, left medial temporal gyrus, left superior temporal gyrus, left medial frontal gyrus, left precentral gyrus, right postcentral gyrus in pASD. In addition, ALFF values in ROI-1, DC values in ROI-3 were positively correlated with AQ scores in pASD (ρ1 = 0.298, P1 = 0.007; ρ2 = 0.220, P2 = 0.040), while FC values between ROI-1 and right ACC were negatively correlated with AQ scores (ρ3 = −0.334, P3 = 0.002).Conclusion: rsfMRI metrics could be used as biomarkers to reveal the underlying neurobiological feature of ASD for unaffected parents. (shrink)

The symplectic quantization scheme proposed for matter scalar fields in the companion paper (Gradenigo and Livi, arXiv:2101.02125, 2021) is generalized here to the case of space–time quantum fluctuations. That is, we present a new formalism to frame the quantum gravity problem. Inspired by the stochastic quantization approach to gravity, symplectic quantization considers an explicit dependence of the metric tensor gμν\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$g_{\mu \nu }$$\end{document} on an additional time variable, named intrinsic time (...) at variance with the coordinate time of relativity, from which it is different. The physical meaning of intrinsic time, which is truly a parameter and not a coordinate, is to label the sequence of gμν\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$g_{\mu \nu }$$\end{document} quantum fluctuations at a given point of the four-dimensional space–time continuum. For this reason symplectic quantization necessarily incorporates a new degree of freedom, the derivative g˙μν\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\dot{g}}_{\mu \nu }$$\end{document} of the metric field with respect to intrinsic time, corresponding to the conjugated momentum πμν\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\pi _{\mu \nu }$$\end{document}. Our proposal is to describe the quantum fluctuations of gravity by means of a symplectic dynamics generated by a generalized action functional A[gμν,πμν]=K[gμν,πμν]-S[gμν]\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\mathcal {A}}[g_{\mu \nu },\pi _{\mu \nu }] = {\mathcal {K}}[g_{\mu \nu },\pi _{\mu \nu }] - S[g_{\mu \nu }]$$\end{document}, playing formally the role of a Hamilton function, where S[gμν]\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$S[g_{\mu \nu }]$$\end{document} is the standard Einstein–Hilbert action while K[gμν,πμν]\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\mathcal {K}}[g_{\mu \nu },\pi _{\mu \nu }]$$\end{document} is a new term including the kinetic degrees of freedom of the field. Such an action allows us to define an ensemble for the quantum fluctuations of gμν\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$g_{\mu \nu }$$\end{document} analogous to the microcanonical one in statistical mechanics, with the only difference that in the present case one has conservation of the generalized action A[gμν,πμν]\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\mathcal {A}}[g_{\mu \nu },\pi _{\mu \nu }]$$\end{document} and not of energy. Since the Einstein–Hilbert action S[gμν]\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$S[g_{\mu \nu }]$$\end{document} plays the role of a potential term in the new pseudo-Hamiltonian formalism, it can fluctuate along the symplectic action-preserving dynamics. These fluctuations are the quantum fluctuations of gμν\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$g_{\mu \nu }$$\end{document}. Finally, we show how the standard path-integral approach to gravity can be obtained as an approximation of the symplectic quantization approach. By doing so we explain how the integration over the conjugated momentum field πμν\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\pi _{\mu \nu }$$\end{document} gives rise to a cosmological constant term in the path-integral approach. (shrink)

The electronic and muonic hydrogen energy levels are calculated very accurately [1] in Quantum Electrodynamics (QED) by coupling the Dirac Equation four vector (c ,mc2) current covariantly with the external electromagnetic (EM) field four vector in QED’s Interactive Representation (IR). The c -Non Exclusion Principle(c -NEP) states that, if one accepts c as the electron/muon velocity operator because of the very accurate hydrogen energy levels calculated, the one must also accept the resulting electron/muon internal spatial and time coordinate operators (ISaTCO) (...) derived directly from c without any assumptions. This paper does not change any of the accurate QED calculations of hydrogen’s energy levels, given the simplistic model of the proton used in these calculations [1]. The Proton Radius Puzzle [2, 3] may indicate that new physics is necessary beyond the Standard Model (SM), and this paper describes the bizarre, and very different, situation when the electron and muon are located “inside” the spatially extended proton with their Centers of Charge (CoCs) orbiting the proton at the speed of light in S energy states. The electron/muon center of charge (CoC) is a structureless point that vibrates rapidly in its inseparable, non-random vacuum whose geometry and time structure are defined by the electron/muon ISaTCO discrete geometry. The electron/muon self mass becomes finite in a natural way due to the ISaTCOs cutting off high virtual photon energies in the photon propagator. The Dirac-Maxwell-Wilson (DMW) Equations are derived from the ISaTCO for the EM fields of an electron/muon, and the electron/muon “look” like point particles in far field scattering experiments in the same way the electric field from a sphere with evenly distributed charge “e” “looks” like a point with the same charge in the far field (Gauss Law). The electron’s/muon’s three fluctuating CoC internal spatial coordinate operators have eight possible eigenvalues [4, 5, 6] that fall on a spherical shell centered on the electron’s CoM with radius in the rest frame. The electron/muon internal time operator is discrete, describes the rapid virtual electron/positron pair production and annihilation. The ISaTCO together create a current that produce spin and magnetic moment operators, and the electron and muon no longer have “intrinsic” properties since the ISaTCO kinematics define spin and magnetic moment properties. (shrink)

Electromechanical actuators are more and more widely used as actuation devices in flight control system of aircrafts and helicopters. The reliability of EMAs is vital because it will cause serious accidents if the malfunction of EMAs occurs, so it is significant to detect and diagnose the fault of EMAs timely. However, EMAs often run under variable conditions in realistic environment, and the vibration signals of EMAs are nonlinear and nonstationary, which make it difficult to effectively achieve fault diagnosis. This paper (...) proposed a fault diagnosis method of electromechanical actuators based on variational mode decomposition multifractal detrended fluctuation analysis and probabilistic neural network. First, the vibration signals were decomposed by VMD into a number of intrinsic mode functions. Second, the multifractal features hidden in IMFs were extracted by using MFDFA, and the generalized Hurst exponents were selected as the feature vectors. Then, the principal component analysis was introduced to realize dimension reduction of the extracted feature vectors. Finally, the probabilistic neural network was utilized to classify the fault modes. The experimental results show that this method can effectively achieve the fault diagnosis of EMAs even under diffident working conditions. Simultaneously, the diagnosis performance of the proposed method in this paper has an advantage over that of EMD-MFDFA method for feature extraction. (shrink)

Mindfulness and accordant interventions are often used as complementary treatments to psychological or psychosomatic problems. This has also been gradually integrated into daily lives for the promotion of psychological well-being in non-clinical populations. The experience of mindful acceptance in a non-judgmental way brought about the state, which was less interfered by a negative effect. Mindfulness practice often begins with focused attention meditation restricted to an inner experience. We postulate that the brain areas related to an interoceptive function would demonstrate an (...) intrinsic functional change after mindfulness training for the mindful novices along with paying more attention to internal processes. To further explore the influence of mindfulness on the organization of the brain regions, both functional connectivity in the voxel and the region of interest level were calculated. In the current study, 32 healthy volunteers, without any meditation experiences, were enrolled and randomly assigned to a mindfulness-based stress reduction group or control group. Participants in the MBSR group completed 8 weeks of mindfulness-based stress reduction and rated their mindfulness skills before and after MBSR. All subjects were evaluated via resting-state functional MRI in both baselines and after 8 weeks. They also completed a self-report measure of their state and trait anxiety as well as a positive and negative affect. Pre- and post-MBSR assessments revealed a decreased amplitude of low-frequency fluctuations in the right anterior cingulate gyrus, left anterior and posterior insula, as well as left superior medial frontal gyrus in MBSR practitioners. Strengthened FC between right anterior cingulate cortex and aIC.R was observed. The mean ALFF values of those regions were inversely and positively linked to newly acquired mindful abilities. Along with a decreased negative affect score, our results suggest that the brain regions related to attention and interoceptive function were involved at the beginning of mindfulness. This study provides new clues in elucidating the time of evaluating the brain mechanisms of mindfulness novices. (shrink)

BackgroundTemporal lobe epilepsy is the most prevalent refractory focal epilepsy and is more likely accompanied by cognitive impairment. The fully understanding of the neuronal activity underlying TLE is of great significance.ObjectiveThis study aimed to comprehensively explore the potential brain activity abnormalities affected by TLE and detect whether the changes were associated with cognition.MethodsSix static intrinsic brain activity indicators [amplitude of low-frequency fluctuation, fractional ALFF, regional homogeneity, degree centrality, global signal correlation, and voxel-mirrored homotopic connectivity ] and their corresponding dynamic (...) indicators, such as dynamic ALFF, dynamic fALFF, dynamic ReHo, dynamic DC, dynamic VMHC, and dynamic GSCorr, in 57 patients with unilateral TLE and 42 healthy volunteers were compared. Correlation analyses were also performed between these indicators in areas displaying group differences and cognitive function, epilepsy duration, and severity.ResultsMarked overlap was present among the abnormal brain regions detected using various static and dynamic indicators, primarily including increased ALFF/dALFF/fALFF in the bilateral medial temporal lobe and thalamus, decreased ALFF/dALFF/fALFF in the frontal lobe contralateral to the epileptogenic side, decreased fALFF, ReHo, dReHo, DC, dDC, GSCorr, dGSCorr, and VMHC in the temporal neocortex ipsilateral to the epileptogenic foci, decreased dReHo, dDC, dGSCorr, and dVMHC in the occipital lobe, and increased ALFF, fALFF, dfALFF, ReHo, and DC in the supplementary motor area ipsilateral to the epileptogenic foci. Furthermore, most IBA indicators in the abnormal brain region significantly correlated with the duration of epilepsy and several cognitive scale scores.ConclusionThe combined application of static and dynamic IBA indicators could comprehensively reveal more real abnormal neuronal activity and the impairment and compensatory mechanisms of cognitive function in TLE. Moreover, it might help in the lateralization of epileptogenic foci and exploration of the transmission and inhibition pathways of epileptic activity. (shrink)

Human neural and behavioral activities have been reported to exhibit fractal dynamics known as 1/f noise, which is more aptly named 1/f scaling. Some argue that 1/f scaling is a general and pervasive property of the dynamical substrate from which cognitive functions are formed. Others argue that it is an idiosyncratic property of domain‐specific processes. An experiment was conducted to investigate whether 1/f scaling pervades the intrinsic fluctuations of a spoken word. Ten participants each repeated the word bucket (...) over 1,000 times, and fluctuations in acoustic measurements across repetitions generally followed the 1/f scaling relation, including numerous parallel yet distinct series of 1/f fluctuations. On the basis of work showing that 1/f scaling is a universal earmark of metastability, it is proposed that the observed pervasiveness of 1/f fluctuations in speech reflects the fact that cognitive functions are formed as metastable patterns of activity in brain, body, and environment. (shrink)

The term “value of life” can refer to life’s intrinsic dignity: something nonincremental and time-unaffected in contrast to the fluctuating, incremental “value” of our lives, as they are longer or shorter and more or less flourishing. Human beings are equal in their basic moral importance: the moral indignities we condemn in the treatment of e.g. those with dementia reflect the ongoing human dignity that is being violated. Indignities licensed by the person in advance remain indignities, as when people might (...) volunteer their living, unconscious bodies for surrogacy or training in amputation techniques. Respect for someone’s dignity is significantly impacted by a failure to value that person’s very existence, whatever genuine respect and good will is shown by wanting the person’s life to go well. Valuing and respecting life is not, however, vitalism: there can be good and compelling reasons for eschewing some means of prolonging life. (shrink)

Intrinsic gait variability, i.e., fluctuations in the regularity of gait patterns between repetitive cycles, is inherent to the sensorimotor system and influenced by factors such as age and pathology. Increased GV is associated with gait impairments in individuals with cerebral palsy and has been mainly studied based on spatiotemporal parameters. The present study aimed to describe kinematic GV in young people with CP and its associations with clinical impairments [i.e., passive range of motion, muscle weakness, reduced selective motor (...) control, and spasticity]. This retrospective study included 177 participants with CP representing 289 clinical gait analyses [n = 172 for unilateral CP vs. 117 for bilateral CP ]. As variability metrics, Root Mean Square Deviation for nine lower-limb kinematic parameters and Gait Standard Deviation – as composite score of the kinematic parameters – were computed for the affected and most affected side, respectively, as defined by clinical scores. GaitSD was then computed for the non/less-affected side for between leg comparisons. Uni- and multivariate linear regressions were subsequently performed on GaitSD of the affected/most affected side with all clinical impairments as independent variables. Highest RMSD were found in the transverse plane, for distal joints in the sagittal plane and for foot progression. GaitSD was not different between uCP and bCP but higher in the non-affected vs. affected side in uCP. GaitSD was associated with age, gait deviation index, muscle weakness, selectivity, and pROM. After adjustment for age and GDI, GaitSD remained associated with muscle weakness and selectivity. Kinematic GV can be expressed as global indicator of variability in young people with CP given the strong correlation of RMSD for lower-limb kinematic parameters. In terms of asymmetry, increased variability of the non-affected vs. affected side may indicate contralateral compensation mechanisms in uCP. Notably muscle weakness and selectivity – but not spasticity – were associated with GaitSD. Further studies need to explore the clinical relevance of kinematic GV in CP to support the interpretation of clinical gait analyses and therapeutic decision-making. (shrink)

All capitalist economies experience fluctuations in employment and economic activity around a long-term growth rate. How is this cyclical pattern of growth to be explained? Are the causes of fluctuations in output and employment to be found outside the system or are they intrinsic to the system? Will the long-term growth rate correspond to the growth of the labour force? It is the search for answers to these questions which motivates Peter Skott's analysis. The book develops a (...) theory of dynamic interaction between three types of agent: firms, households and banks. Firms are profit-maximisers operating under conditions of imperfect competition and their production and investment decisions are influenced by monetary and financial factors as well as by the state of the labour market. Households hold financial assets, supply labour and have a direct influence on nominal wage rates. Banks set interest rates on bank loans and deposits. No assumptions are made about nominal price rigidities and the capital-output ratio is determined endogenously. Using a framework of analysis which is rigorous and which does not exclude traditional neoclassical mechanisms, this book demonstrates the validity of important Marxian and Keynesian insights into the growth process. (shrink)

This paper presents an argument that certain AI safety measures, rather than mitigating existential risk, may instead exacerbate it. Under certain key assumptions - the inevitability of AI failure, the expected correlation between an AI system's power at the point of failure and the severity of the resulting harm, and the tendency of safety measures to enable AI systems to become more powerful before failing - safety efforts have negative expected utility. The paper examines three response strategies: Optimism, Mitigation, and (...) Holism. Each faces challenges stemming from intrinsic features of the AI safety landscape that we term Bottlenecking, the Perfection Barrier, and Equilibrium Fluctuation. The surprising robustness of the argument forces a re-examination of core assumptions around AI safety and points to several avenues for further research. (shrink)

Climate dynamics and trends have significant environmental and socioeconomic impacts; however, in the Benin Republic, they are generally studied with diverse statistical methods ignoring the nonstationarity, nonlinearity, and self-similarity characteristics contained in precipitation time series. This can lead to erroneous conclusions and an unclear understanding of climatic dynamics. Based on daily precipitation data observed in the six synoptic stations of Benin Republic, in the period from 1951 to 2010, we have proposed determining the local trends of precipitations, investigating precipitation nonlinear (...) dynamics, and assessing climatic shift in the study period by Ensemble Empirical Mode Decomposition and Multifractal Detrended Fluctuation Analysis method. To overcome the detrending issue in the standard MFDFA method, the EEMD algorithm is embedded into the MFDFA. The study period is subdivided into three subperiods: 1951–1970, 1971–1990, and 1991–2010. Intrinsic Mode Functions are obtained according to the climatic region in which the stations are located. Results show that precipitation variation is significantly governed by the five first IMFs, in which oscillation periods vary from 1 to 25 days. The trend curves decrease at all the synoptic stations, and their slope values vary accordingly to the subperiods. Referring to the values of the multifractal spectrum parameters, α 0, and the width of the spectrum w, consistent changes are observed regardless of the subperiods and the concerned stations. The spatial and temporal variability of precipitation indicates that the multifractal properties are good indicators for assessing changes in precipitation dynamics, and the changes in their features could be explained by the global change than by the local climate variation. Despite the observed differences in multifractal spectra properties from the three subperiods, it is not possible to verify the subdivision of 1951–2010 in three subperiods as it is done by previous studies in West Africa. Our findings can be used in the validation of global and regional climate models since a valid model should explain empirically detected scaling properties in observed data. (shrink)

The ongoing controversy about the possibility of directed mutations in bacteria is examined for its methodological, and thereby philosophical, implications. The method of fluctuation analysis, widely used to investigate whether mutations are random or directed, is described and subjected to a conceptual critique which shows that it cannot decide whether some mutations are directed while most are random. In this context, recent experiments that exploit this possibility to suggest that directed mutations occur in bacteria are described. Interpretive and experimental responses (...) to such claims are briefly analyzed. Finally it is argued that mere statistical analysis, such as fluctuation analysis, cannot resolve this dispute. What will probably be required is an investigation of mechanisms of mutagenesis, an investigation that is intrinsically reductive. (shrink)

Owing to the adverse impact of the COVID-19 pandemic on world economies, it is expected that information flows between commodities and uncertainties have been transformed. Accordingly, the resulting twisted risk among commodities and related uncertainties is presumed to rise during stressed market conditions. Therefore, investors feel pressured to find safe haven investments during the pandemic. For this reason, we model a mixture of asymmetric and non-linear bi-directional causality between global commodities and uncertainties at different frequencies through the information flow theory. (...) Consequently, we utilise the complete ensemble empirical mode decomposition with adaptive noise and the Rényi effective transfer entropy techniques to establish the dynamic flow of information. The intrinsic mode functions from the CEEMDAN are carefully extracted into multi-frequencies through cluster analysis to reconstruct the series into high, medium, and low frequencies in addition to the residue. We utilise daily data from December 31st, 2019, to March 31st, 2021, to provide insights into the COVID-19 pandemic. The correlation coefficients and variances demonstrate that the high frequency which measures the short-term dynamics is the dominant frequency, suggesting short-lived market fluctuations relative to real economic growth for institutional investors. Moreover, outcomes from the multi-frequency entropy indicate a negative bi-directional causality of information flow between global commodities and uncertainties, especially in the long term. Generally, the findings present pertinent inferences for portfolio diversification, policy decisions, and risk management schemes for global commodities and markets volatilities. We, therefore, advocate that market volatilities act as effective hedges for global commodities, and they clearly act as balancing assets rather than substitutes in the long-term dynamics of the COVID-19 pandemic. Investors who delayed in investing within financial markets of commodities and market volatilities are likely to minimise their portfolio risks. (shrink)

In this paper, we examine the pioneering research on electronic noise—the current fluctuations in electronic circuit devices due to their intrinsic physical characteristics rather than their defects—in Germany and the U.S. during the 1910s–1920s. Such research was not just another demonstration of the general randomness of the physical world Einstein’s work on Brownian motion had revealed. In contrast, we stress the importance of a particular engineering context to electronic noise studies: the motivation to design and improve high-gain thermionic-tube (...) amplifiers for radio and wired communications. Engineering scientists’ endeavors to understand electronic noise started in 1918, when Walter Schottky at Siemens formulated a theory of “shot noise,” current fluctuations owing to the random emissions of discrete electrons in a tube. Schottky’s theory was revised and experimentally tested at Siemens, General Electric, and AT&T during the 1920s, leading to the discoveries of several other types of noise and an increasing interest in the thermal fluctuations in electronic circuits. In 1925–1928, J.B. Johnson and Harry Nyquist at Bell Labs developed a theory of thermal noise for any electrical resistor at a non-zero temperature. Although these studies were initiated to chart the fundamental performance limit of electronic technology, they ended up assisting the empirical determination of individual electronic components’ characteristics. (shrink)

Neurovascular coupling (NVC), the transient regional hyperemia following the evoked neuronal responses, is the basis of blood oxygenation level-dependent techniques and is generally adopted across physiological conditions, including the intrinsic resting state. However, the possibility of neurovascular dissociations across physiological alterations is indicated in the literature. To examine the NVC stability across sleep–wake states, we used electroencephalography (EEG) as the index of neural activity and functional magnetic resonance imaging (fMRI) as the measure of cerebrovascular response. Eight healthy adults were (...) recruited for simultaneous EEG-fMRI recordings in nocturnal sleep. We compared the cross-modality (EEG vs. fMRI) consistency of functional indices (spectral amplitude and functional connectivity) among five states of wakefulness and sleep (state effect). We also segregated the brain into three main partitions (anterior, middle and posterior) for spatial assessments (regional effect). Significant state effects were found on δ, α and fMRI indices and regional effects on the α and fMRI indices. However, the cross-state EEG changes in spectral amplitude and functional connectivity did not consistently match the changes in the fMRI indices across sleep–wake states. In spectral amplitude, the δ band peaked at the N3 stage for all brain regions, while the fMRI fluctuation amplitude peaked at the N2 stage in the central and posterior regions. In regional connectivity, the inter-hemispheric connectivity of the δ band peaked at the N3 stage for all regions, but the bilateral fMRI connectivity showed the state changes in the anterior and central regions. The cross-modality inconsistencies across sleep–wake states provided preliminary evidence that the neurovascular relationship may not change in a linear consistency during NREM sleep. Thus, caution shall be exercised when applying the NVC presumption to investigating sleep/wake transitions, even among healthy young adults. (shrink)

Pride is a fundamental element in Hume's description of human nature. An important part of the secondary literature on Hume is devoted to this passion. However, no one, as far as I am aware, takes seriously the fact that pride often appears in pairs with vanity. In Book 2 of the Treatise, pride is defined as the passion one feels when society recognizes his connection to a ‘cause’, composed by a ‘subject’ and a (positive) ‘quality’. Conversely, no definition of vanity (...) is provided. Despite Hume's fluctuating vocabulary, I hold that a conceptual difference between pride and vanity exists. To support this claim, I analyse the common features of these two passions, showing that both pride and vanity (a) are indirect passions, (b) are self-regarding passions, and (c) have the same structure. Supported by textual evidence, I then claim that vanity is a desire of reputation, a desire to feel pride, when pride is not (yet) in place, because its cause is only imaginary and not real. Nonetheless, I underscore that, at times, ‘vanity’ means simply pride and call for greater attention on this ongoing oscillation. In conclusion, I explore the implications of this account of vanity for social interactions in Hume's philosophy, which illustrates its intrinsic ambivalence. (shrink)

Through statistical analysis of datasets describing single cell shape following systematic gene depletion, we have found that the morphological landscapes explored by cells are composed of a small number of attractor states. We propose that the topology of these landscapes is in large part determined by cell‐intrinsic factors, such as biophysical constraints on cytoskeletal organization, and reflects different stable signaling and/or transcriptional states. Cell‐extrinsic factors act to determine how cells explore these landscapes, and the topology of the landscapes themselves. (...) Informational stimuli primarily drive transitions between stable states by engaging signaling networks, while mechanical stimuli tune, or even radically alter, the topology of these landscapes. As environments fluctuate, the topology of morphological landscapes explored by cells dynamically adapts to these fluctuations. Finally we hypothesize how complex cellular and tissue morphologies can be generated from a limited number of simple cell shapes. (shrink)

ArgumentSociologists and historians of science, such as Richard Whitley and Stephen Hilgartner, identified a culturally dominant discourse of science popularization in the broader society. In this dominant view, a clear distinction is maintained between scientific knowledge and popularized knowledge. Popularization of science is seen as the process of transmitting real science to a lay public. This discourse on science popularization was criticized by Whitley and Hilgartner as an inadequate simplification. Yet, the battered traditional model of popularization remains remarkably resistant to (...) these theoretical attacks. In this paper I will argue, based on research of the output of the Belgian economist Gustave de Molinari, and more specifically, his opinion on the role of government in economic life, that the boundary between science and popularization in political economy is not clear and that the status of scientists fluctuates over time and in different contexts. It is therefore impossible for historians or economists to distinguish science from popularization based on the essential characteristics or intrinsic quality of the work. De Molinari's ideas are followed through the different media of science and journalism. Although de Molinari himself differentiated between his scientific and “popular” work, the boundary between science and popularization proves to be highly permeable, in both directions. (shrink)

Recent evidence indicates that transcriptional bursts are intrinsically amplified by messenger RNA cytoplasmic processing to generate large stochastic fluctuations in protein levels. These fluctuations can be exploited by cells to enable probabilistic bet‐hedging decisions. But large fluctuations in gene expression can also destabilize cell‐fate commitment. Thus, it is unclear if cells temporally switch from high to low noise, and what mechanisms enable this switch. Here, the discovery of a post‐transcriptional mechanism that attenuates noise in HIV is reviewed. (...) Early in its life cycle, HIV amplifies transcriptional fluctuations to probabilistically select alternate fates, whereas at late times, HIV utilizes a post‐transcriptional feedback mechanism to commit to a specific fate. Reanalyzing various reported post‐transcriptional negative feedback architectures reveals that they attenuate noise more efficiently than classic transcriptional autorepression, leading to the derivation of an assay to detect post‐transcriptional motifs. It is hypothesized that coupling transcriptional and post‐transcriptional autoregulation enables efficient temporal noise control to benefit developmental bet‐hedging decisions. (shrink)

The modern concept of science is rooted in a metaphysical option of materialist monism. The religious beliefs are inevitably founded on the pluralist concept of reality. Hence, the conflict is inevitable. Monism blames religion for producing illusions, while religion accuses the sciences of being epistemologically self-mutilated by their intrinsic reductionism. There exists a third realm of cognition, namely the growing bulk of knowledge. It is relatively independent of temporary fluctuations of "scientific standards" and "scientific methodologies". It is also (...) independent of the religious beliefs founded on some extraordinary, miraculous, "supranatural" events. The knowledge (a sufficiently accurate orientation in the real world) is present both in the highly civilized communities and in the so called "primitive" illiterate populations. Technical achievements confirm the essential accuracy of the knowledge and, at the same time, give some support to the foundations of teleological concepts and consequently to many of religious beliefs. (shrink)

ArgumentDuring the interwar period research on turbulence met with interest from different areas: in aeronautical engineering turbulence became a subject of experimental study in wind tunnels; in naval architecture and hydraulic engineering turbulence research was on the agenda because of its role for skin friction; applied mathematicians and theoretical physicists struggled with the problem to determine the onset of turbulence from the fundamental hydrodynamic equations; experimental physicists developed techniques to measure the velocity fluctuations of turbulent flows. In this paper (...) I describe the rise of turbulence in the 1920s and 1930s as a research field under the label of applied mechanics. Although the focus is on Germany, the international development of this research field is illuminated by the role which Ludwig Prandtl played as its acknowledged “chief” (G. I. Taylor). I argue that the multifaceted character of this research field calls for an epistemology and historiography which intrinsically takes the interaction of science and engineering into account. (shrink)

The present study aims at giving factual support to the thesis that the Parmenides is serious in intention, rigorous in logical demonstration, and stylistically meticulous in its original composition. While this consideration may be tedious, still it is useful. Against a past history which has claimed to find the tone hilarious, the logic fallacious, the work inauthentic, the text in need of bracketing by divination, the whole incoherent— against these eccentricities a certain firm sobriety seems called for. I hope that (...) my conclusions find support and persist through fluctuations of philosophic and philological styles.The main difficulty with my thesis is that the text as we now have it (in Burnet's and Dies' editions) shows exceptions to every rule that might apply to style and even to logical structure. Thus it is almost but not quite uniformly true that each theorem opens with a theorem statement; that each is marked by a "questioning" response; that each deduction is valid when formalized in propositional calculus; and so on. Are the exceptions the result of careless composition; are they deliberate warnings not to take the proofs too seriously; or are they the result of errors in transmission? One way to test this is to reconstruct early versions of the text: if these show more logical rigor than the later versions the notion of a wholly valid original is supported; if they do not, the result may point toward the need for a less serious interpretation. A second thing to look for is the possibility that, here and there, parts of a coherent original text are uniquely conserved in sources other than the principal mss, B,T, and W. This assumes, of course, that the "original" text in question is the one with the best logical form, and that assumption seems justified. As a matter of fact, later copyings almost universally show deterioration, not improvement in style and logic.My textual findings are more compatible with some lines of interpretation than with others. Thus I offer some reasons for not accepting treatments of the work as a joke, mystical revelation, or abrupt metaphysical revision. The structure of the dialogue is best explained, I think, by reading it as an indirect proof that some non-Platonic interpretations of the theory of forms are unsatisfactory. In particular, these are the Megarian version (represented in the first part of the dialogue by Zeno, in the second by the First Hypothesis), and the Anaxagorean version put forward by Eudoxus (represented in the first part by Cephalus and his friends from Clazomenae, in the second by the Second Hypothesis). At the same time, the dialogue shows the need for a philosophic method other than the "hypothetical— deductive" way of dianoia; presumably this other method is the "dialectic" discussed in Republic VII. It also follows that any interpretation of the Phaedo which falls into either the Eudoxian or Megarian difficulties was not— at least at the date of the Parmenides—Plato's intended reading.Findings concerning the relations and reliability of the manuscripts of this dialogue also apply to the texts of the other Platonic dialogues which these mss contain.Further, the Parmenides is such an important work both historically and intrinsically that any insight which textual study can bring to its interpretation is a contribution to Western philosophy. (shrink)

SummaryThe meaning of the term “health” is properly the subject of social, rather than natural, investigation. The structure of modern industrial capitalist society appears to materially and unavoidably produce a meaning of “health” intrinsically involving substantially preventable disease. Because in such a society private investment responds to cyclical and geographic fluctuations in rates of return and competitive labor markets, much of the disease structure (heart disease, stroke, kidney failure, and cancer, among others) encompasses diseases which captive citizens cannot afford (...) to do without. To prevent those diseases through environmental and workplace cleanup, full employment and geographic capital stability is to drive away the very private capital on which economic life is based. Consequently, those diseases are as intrinsic to modern capitalist society as the law of supply and demand and are, therefore, a characteristic component of the meaning of “health,” the socially optimum level of organismic condition, in this epoch. A necessary condition for the emancipation of “health” from socially preventable disease would appear to be the social, rather than private, control of production and accumulation. (shrink)

An information-theoretic approach is shown to derive both the classical weak-field equations and the quantum phenomenon of metric fluctuation within the Planck length. A key result is that the weak-field metric $\bar h_{\mu \nu } $ is proportional to a probability amplitude φuv, on quantum fluctuations in four-position. Also derived is the correct form for the Planck quantum length, and the prediction that the cosmological constant is zero. The overall approach utilizes the concept of the Fisher information I acquired (...) in a measurement of the weak-field metric. An associated physical information K is defined as K=I−J, where J is the information that is intrinsic to the physics (stress-energy tensor Tμv) of the measurement scenario. A posited conservation of information change δI=ΔJ implies a variational principle δK=0. The solution is the weak-field equations in the metric $\bar h_{\mu \nu } $ and associated equations in the probability amplitudes φuv. The gauge condition φ v uv =0 (Lorentz condition) and conservation of energy and momentum Tv μv=0 are used. A well-known “bootstrapping” argument allows the weak-field assumption to be lifted, resulting in the usual Einstein field equations. A special solution of these is well known to be the geodesic equations of motion of a particle. Thus, the information approach derives the classical field equations and equations of motion, as well as the quantum nature of the probability amplitudes φuv. (shrink)

Argumentation is a form of communication, rather than an application of(formal) logic, and is used in communicative activity as a means forinquiry, although it is more typically thought of as bringing inquiry toclosure. Thus interpretation is an intrinsic and crucial aspect ofconversational (interactive) argumentation. In order to further thisunderstanding of argumentative activity, I propose a procedure forinterpretation that draws upon hermeneutic phenomenology. In response tocriticisms by argumentation theorists (and others) who understand thistradition as oriented to psychological, perceptual, or textual (...) objects, Iargue that hermeneutic phenomenology supports methods for analysis ofpublic communicative activity. The resulting conception of ’thick argumentation‘ responds to contemporary (postmodern) claims that argumentation valorizes univocity, stasis, and certainty at the expense ofthe pluralism, fluctuation, and range of epistemic results thatcharacterize discourse in the public sphere. (shrink)

In order to resolve the cosmological constant problem, the notion of reference frame is re-examined at the quantum level. By using a quantum non-linear sigma model (Q-NLSM), a theory of quantum spacetime reference frame is proposed. The underlying mathematical structure is a new geometry endowed with intrinsic second central moment (variance) or even higher moments of its coordinates, which generalizes the classical Riemannian geometry based on only first moment (mean) of its coordinates. The second central moment of the coordinates (...) directly modifies the quadratic form distance which is the foundation of the Riemannian geometry. At semi-classical level, the second central moment introduces a flow which continuously deforms the Riemannian geometry driven by its classical Ricci curvature, which is known as the Ricci flow. A generalized equivalence principle of quantum version is also proposed to interpret the new geometry endowed with at least second moment. As a consequence, the spacetime is stabilized against quantum fluctuation, and the cosmological constant problem is resolved within the framework. With an isotropic positive curvature initial condition, the long flow time solution of the Ricci flow exists, the accelerating expansion universe at cosmic scale is an observable effect of the spacetime deformation of the normalized Ricci flow. A deceleration parameter − 0.67 consistent with measurement is obtained by using the reduced volume method introduced by Perelman. Effective theory of gravity within the framework is also discussed. (shrink)

Between-subject variability in cognitive performance has been related to inter-individual differences in functional brain networks. Targeting the dorsal attention network we questioned whether resting-state functional connectivity within the DAN can predict individual performance in spatial attention tasks and whether there is short-term adaptation of DAN-FC in response to task engagement. Twenty-seven participants first underwent resting-state fMRI, they subsequently performed different tasks of spatial attention [including visual search ] and immediately afterwards received another rs-fMRI. Intra- and inter-hemispheric FC between core hubs (...) of the DAN, bilateral intraparietal sulcus and frontal eye field, was analyzed and compared between PRE and POST. Furthermore, we investigated rs-fMRI-behavior correlations between the DAN-FC in PRE/POST and task performance parameters. The absolute DAN-FC did not change from PRE to POST. However, different significant rs-fMRI-behavior correlations were revealed for intra-/inter-hemispheric connections in the PRE and POST run. The stronger the FC between left FEF and IPS before task engagement, the better was the learning effect in VS. And the faster the VS, the stronger was the FC between right FEF and IPS after task engagement. To conclude, DAN-FC relates to the individual performance in spatial attention tasks supporting the view of functional brain networks as priors for cognitive ability. Despite a high inter- and intra-individual stability of DAN-FC, the change of FC-behavior correlations after task performance possibly indicates task-related adaptation of the DAN, underlining that behavioral experiences may shape intrinsic brain activity. However, spontaneous state fluctuations of the DAN-FC over time cannot be fully ruled out as an alternative explanation. (shrink)

By analyzing a gedanken experiment designed to measure the distance l between two spatially separated points, we find that this distance cannot be measured with uncertainty less than (ll 2 P) 1/3 , considerably larger than the Planck scale lP (or the string scale in string theories), the conventional-wisdom uncertainty in distance measurements. This limitation to space-time measurements is interpreted as resulting from quantum fluctuations of space-time itself. Thus, at very short distance scales, space-time is “foamy.” This intrinsic (...) foaminess of space-time provides another source of noise in the interferometers. The LIGO/VIRGO and LISA generations of gravity-wave interferometers, through future refinements, are expected to reach displacement noise levels low enough to test our proposed degree of foaminess in the structure of space-time. (shrink)

In 1974 perfect crystal interferometry has been developed and immediately afterwards the 4π-symmetry of spinor wave-functions has been verified. The new method opened a new access to the observation of intrinsic quantum phenomena. Spin-superposition, quantum state reconstruction and quantum beat effects are examples of such investigations. In this connection efforts have been made to separate and measure various dynamical and geometrical phases. Non-cyclic and non-adiabatic topological phases have been identified and their stability against various fluctuations and dissipative forces (...) has been investigated by means of ultra-cold neutrons. An entanglement between different degrees of freedom of a single neutron system demonstrated the contextuality feature of quantum mechanics. In its continuation this yields to Kochen-Specker theorem like investigations providing a new basis for information processing and for the understanding of quantum physics in general. All investigations show the equivalence of various phase spaces and show how physical phenomena are correlated by quantum laws. Some curiosa occurred during the experiments and some epistemological aspects will be discussed as well. (shrink)

Fluctuation phenomena are the ''tip of the iceberg'' revealing the existence, behind even the most quiescent appearing macroscopic states, of an underlying world of agitated, ever-changing microscopic processes. While the presence of these fluctuations can be ignored in some cases, e.g. if one is satisfied with purely thermostatic description of systems in equilibrium, they are central to the understanding of other phenomena, e.g. the nucleation of a new phase following the quenching of a system into the co-existence region. This (...) volume, originally published several years ago, has stood the test of time well, as interest in fluctuation phenomena continues to grow. It contains a collection of review articles, some of them updated, written by experts in the field, on the subject of fluctuation phenomena. Some of the articles are of a very general nature discussing the modern mathematical formulation of the problems involved, while other articles deal with specific topics such as kinetics of phase transitions and conductivity in solids. The juxtaposition of the variety of physical situations in which fluctuation phenomena play an important role is novel and should give the reader a comprehensive and deeper insight into this fascinating subject. (shrink)

What reasons for action do we have? What explains why we have these reasons? This paper articulates some of the basic structural features of a theory that would provide answers to these questions. According to this theory, reasons for action are all grounded in intrinsic values, but in a way that makes room for a thoroughly non-consequentialist view of the way in which intrinsic values generate reasons for aaction.

Several intrinsic/extrinsic distinctions amongst properties, current in the literature, are discussed and contrasted. The proponents of such distinctions tend to present them as competing, but it is suggested here that at least three of the relevant distinctions (including here that between non-relational and relational properties) arise out of separate perfectly legitimate intuitive considerations: though of course different proposed explications of the informal distinctions involved in any one case may well conflict. Special attention is paid to the question of whether (...) a single notion of property is capable of supporting the various distinctions. (shrink)

The standard counterexamples to David Lewis’s account of intrinsicality involve two sorts of properties: identity properties and necessary properties. Proponents of the account have attempted to deflect these counterexamples in a number of ways. This paper argues that none of these moves are legitimate. Furthermore, this paper argues that no account along the lines of Lewis’s can succeed, for an adequate account of intrinsicality must be sensitive to hyperintensional distinctions among properties.

Fluctuating asymmetry is more a signal of genetic fitness than a marker observable only to the researcher. Hence, it has to be demonstrated that low FA is an honest signal of genetic quality; this has not been demonstrated in Gangestad & Simpson's otherwise useful review.

We have some of our properties purely in virtue of the way we are. (Our mass is an example.) We have other properties in virtue of the way we interact with the world. (Our weight is an example.) The former are the intrinsic properties, the latter are the extrinsic properties. This seems to be an intuitive enough distinction to grasp, and hence the intuitive distinction has made its way into many discussions in philosophy, including discussions in ethics, philosophy of (...) mind, metaphysics, epistemology and philosophy of physics. Unfortunately, when we look more closely at the intuitive distinction, we find reason to suspect that it conflates a few related distinctions, and that each of these distinctions is somewhat resistant to analysis. (shrink)

Erik Wielenberg [2014] and Mark Murphy [2017], [2018] have defended a series of arguments for the conclusion that creatures are not good intrinsically. In response, I take two steps. First, I introduce a conception of intrinsic value that makes created intrinsic value unproblematic. Second, I respond to their arguments in turn. The first argument is from the sovereignty-aseity intuition and an analysis of intrinsicality that makes derivative good extrinsic. I challenge the analysis. The second comes from a conception (...) of perfection where God exhausts all possibilities for goodness. I challenge this conception. The third comes from the contingency of creation and the internal logic of intrinsic value. I challenge the assumption that connects the two. I then present an argument from reference magnetism that the only conception of God, God's perfections, and religious language that makes it plausible that the sentence "God is intrinsically good and creatures are not" is true involves a strongly univocalist position. A view that is either unstatable or places strong demands on our conception of God, God's perfections and religious language thereby loses plausibility. (shrink)

This book provides an introduction to applied statistical mechanics by considering physically realistic models. It provides a simple and accessible introduction to theories of thermal fluctuations and diffusion, and goes on to apply them in a variety of physical contexts. The first part of the book is devoted to processes in thermal equilibrium, and considers linear systems. Ideas central to the subject, such as the fluctuation dissipation theorem, Fokker-Planck equations and the Kramers-Kroenig relations are introduced during the course of (...) the exposition. The scope is then expanded to include non-equilibrium systems and also illustrates simple nonlinear systems. This book will be of interest to final year undergraduate and graduate students studying statistical mechanics, plasma physics, basic electronics, solid state physics and anyone who wants an accessible introduction to the subject. (shrink)

Intrinsic value has traditionally been thought to lie at the heart of ethics. Philosophers use a number of terms to refer to such value. The intrinsic value of something is said to be the value that that thing has “in itself,” or “for its own sake,” or “as such,” or “in its own right.” Extrinsic value is value that is not intrinsic.

The distribution function associated with a classical gas at equilibrium is considered. We prove that apart from a factorisable multiplier, the distribution function is fully determined by the correlations among local momenta fluctuations. Using this result we discuss the conditions which enable idealised local observers, who are immersed in the gas and form a part of it, to determine the distribution 'from within'. This analysis sheds light on two views on thermodynamic equilibrium, the 'ergodic' and the 'thermodynamic limit' schools, (...) and the relations between them. It also provides an outline for a new definition of equilibrium that is weaker than full ergodicity. Finally, we briefly discuss the possibility that the distribution can be determined by external observers. (shrink)

Fluctuations in attentional state and their relation to goal neglect were examined in the current study. Participants performed a variant of the Stroop task in which attentional state ratings were given prior to each trial. It was found that pre-trial attentional state ratings predicted subsequent trial performance, such that when participants rated their current attentional state as highly focused on the current task, performance tended to be high compared to when participants reported their current attentional state as being unfocused (...) on the current task. This effect was larger for incongruent than congruent trials leading to differences in the magnitude of the Stroop effect as a function of pre-trial attentional state. Furthermore, variability in attentional state was correlated with overall levels of performance, and when attentional state was covaried out, the Stroop effect was greatly reduced. These results suggest a link between fluctuations in pre-trial attentional state and goal neglect. (shrink)