Results for 'Gabriel Leprivier'

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  1.  15
    How does oncogene transformation render tumor cells hypersensitive to nutrient deprivation?Gabriel Leprivier & Poul H. Sorensen - 2014 - Bioessays 36 (11):1082-1090.
    Oncogene activation leads to cellular transformation by deregulation of biological processes such as proliferation and metabolism. Paradoxically, this can also sensitize cells to nutrient deprivation, potentially representing an Achilles' heel in early stage tumors. The mechanisms underlying this phenotype include loss of energetic and redox homeostasis as a result of metabolic reprogramming, favoring synthesis of macromolecules. Moreover, an emerging mechanism involving the deregulation of mRNA translation elongation through inhibition of eukaryotic elongation factor 2 kinase (eEF2K) is presented. The potential consequences (...)
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  2. Semantics of Pictorial Space.Gabriel Greenberg - 2021 - Review of Philosophy and Psychology 1 (4):847-887.
    A semantics of pictorial representation should provide an account of how pictorial signs are associated with the contents they express. Unlike the familiar semantics of spoken languages, this problem has a distinctively spatial cast for depiction. Pictures themselves are two-dimensional artifacts, and their contents take the form of pictorial spaces, perspectival arrangements of objects and properties in three dimensions. A basic challenge is to explain how pictures are associated with the particular pictorial spaces they express. Inspiration here comes from recent (...)
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  3. Beyond Resemblance.Gabriel Greenberg - 2013 - Philosophical Review 122 (2):215-287.
    What is it for a picture to depict a scene? The most orthodox philosophical theory of pictorial representation holds that depiction is grounded in resemblance. A picture represents a scene in virtue of being similar to that scene in certain ways. This essay presents evidence against this claim: curvilinear perspective is one common style of depiction in which successful pictorial representation depends as much on a picture's systematic differences with the scene depicted as on the similarities; it cannot be analyzed (...)
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  4. The Iconic-Symbolic Spectrum.Gabriel Greenberg - 2023 - Philosophical Review 132 (4):579-627.
    It is common to distinguish two great families of representation. Symbolic representations include logical and mathematical symbols, words, and complex linguistic expressions. Iconic representations include dials, diagrams, maps, pictures, 3-dimensional models, and depictive gestures. This essay describes and motivates a new way of distinguishing iconic from symbolic representation. It locates the difference not in the signs themselves, nor in the contents they express, but in the semantic rules by which signs are associated with contents. The two kinds of rule have (...)
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  5. Well Founding Grounding Grounding.Gabriel Oak Rabin & Brian Rabern - 2016 - Journal of Philosophical Logic 45 (4):349-379.
    Those who wish to claim that all facts about grounding are themselves grounded (“the meta-grounding thesis”) must defend against the charge that such a claim leads to infinite regress and violates the well-foundedness of ground. In this paper, we defend. First, we explore three distinct but related notions of “well-founded”, which are often conflated, and three corresponding notions of infinite regress. We explore the entailment relations between these notions. We conclude that the meta-grounding thesis need not lead to tension with (...)
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  6. Varieties of Indefinite Extensibility.Gabriel Uzquiano - 2015 - Notre Dame Journal of Formal Logic 56 (1):147-166.
    We look at recent accounts of the indefinite extensibility of the concept set and compare them with a certain linguistic model of indefinite extensibility. We suggest that the linguistic model has much to recommend over alternative accounts of indefinite extensibility, and we defend it against three prima facie objections.
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  7. Grounding Orthodoxy and the Layered Conception.Gabriel Oak Rabin - 2018 - In Ricki Bliss & Graham Priest (eds.), Reality and its Structure: Essays in Fundamentality. Oxford, UK: Oxford University Press. pp. 37-49.
    Ground offers the hope of vindicating and illuminating an classic philosophical idea: the layered conception, according to which reality is structured by relations of dependence, with physical phenomena on the bottom, upon which chemistry, then biology, and psychology reside. However, ground can only make good on this promise if it is appropriately formally behaved. The paradigm of good formal behavior can be found in the currently dominant grounding orthodoxy, which holds that ground is transitive, antisymmetric, irreflexive, and foundational. However, heretics (...)
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  8.  80
    Objections to the teaching of business ethics.Gael M. McDonald & Gabriel D. Donleavy - 1995 - Journal of Business Ethics 14 (10):839 - 853.
    To date the teaching of business ethics has been examined from the descriptive, prescriptive, and analytical perspectives. The descriptive perspective has reviewed the existence of ethics courses (e.g., Schoenfeldtet al., 1991; Bassiry, 1990; Mahoney, 1990; Singh, 1989), their historical development (e.g., Sims and Sims, 1991), and the format and syllabi of ethics courses (e.g., Hoffman and Moore, 1982). Alternatively, the prescriptive literature has centred on the pedagogical issues of teaching ethics (e.g., Hunt and Bullis, 1991; Strong and Hoffman, 1990; Reeves, (...)
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  9. A neglected resolution of Russell’s paradox of propositions.Gabriel Uzquiano - 2015 - Review of Symbolic Logic 8 (2):328-344.
    Bertrand Russell offered an influential paradox of propositions in Appendix B of The Principles of Mathematics, but there is little agreement as to what to conclude from it. We suggest that Russell's paradox is best regarded as a limitative result on propositional granularity. Some propositions are, on pain of contradiction, unable to discriminate between classes with different members: whatever they predicate of one, they predicate of the other. When accepted, this remarkable fact should cast some doubt upon some of the (...)
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  10. The supreme court and the supreme court justices: A metaphysical puzzle.Gabriel Uzquiano - 2004 - Noûs 38 (1):135–153.
  11.  43
    The Semiotic Spectrum.Gabriel Greenberg - 2011 - Dissertation,
    Because humans cannot know one another’s minds directly, every form of communication is a solution to the same basic problem: how can privately held information be made publicly accessible through manipulations of the physical environment? Language is by far the best studied response to this challenge. But there are a diversity of non-linguistic strategies for representation with external signs as well, from facial expressions and fog horns to chronological graphs and architectural renderings. The general thesis of this dissertation is that (...)
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  12. Content and Target in Pictorial Representation.Gabriel Greenberg - 2018 - Ergo: An Open Access Journal of Philosophy 5.
    This essay argues for a model of pictorial representation which aims to explain the relationship between pictorial content and pictorial accuracy. Focusing on cases where pictures are intended to convey accurate information, the model distinguishes between two fundamental representational relations: on one hand, a picture expresses a content; on the other, it aims at a target scene. Such a picture is accurate when the content it expresses fits the target scene it aims at. In addition, the model follows the traditional (...)
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  13. Plurals and Simples.Gabriel Uzquiano - 2004 - The Monist 87 (3):429-451.
    I would like to discuss the claim that the resources of plural reference and plural quantification are sufficient for the purpose of paraphrasing all ordinary statements apparently concerned with composite material objects into plural statements concerned exclusively with simples.
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  14. Counterfactuals and modality.Gabriel Greenberg - 2021 - Linguistics and Philosophy 44 (6):1255-1280.
    This essay calls attention to a set of linguistic interactions between counterfactual conditionals, on one hand, and possibility modals like could have and might have, on the other. These data present a challenge to the popular variably strict semantics for counterfactual conditionals. Instead, they support a version of the strict conditional semantics in which counterfactuals and possibility modals share a unified quantificational domain. I’ll argue that pragmatic explanations of this evidence are not available to the variable analysis. And putative counterexamples (...)
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  15.  47
    DBS and Autonomy: Clarifying the Role of Theoretical Neuroethics.Peter Zuk & Gabriel Lázaro-Muñoz - 2019 - Neuroethics 14 (1):83-93.
    In this article, we sketch how theoretical neuroethics can clarify the concept of autonomy. We hope that this can both serve as a model for the conceptual clarification of other components of PIAAAS and contribute to the development of the empirical measures that Gilbert and colleagues [1] propose.
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  16.  23
    DBS and Autonomy: Clarifying the Role of Theoretical Neuroethics.Peter Zuk & Gabriel Lázaro-Muñoz - 2019 - Neuroethics 14 (1):83-93.
    In this article, we sketch how theoretical neuroethics can clarify the concept of autonomy. We hope that this can both serve as a model for the conceptual clarification of other components of PIAAAS and contribute to the development of the empirical measures that Gilbert and colleagues [1] propose.
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  17. Fundamentality physicalism.Gabriel Oak Rabin - forthcoming - Inquiry: An Interdisciplinary Journal of Philosophy (1):77-116.
    ABSTRACT This essay has three goals. The first is to introduce the notion of fundamentality and to argue that physicalism can usefully be conceived of as a thesis about fundamentality. The second is to argue for the advantages of fundamentality physicalism over modal formulations and that fundamentality physicalism is what many who endorse modal formulations of physicalism had in mind all along. Third, I describe what I take to be the main obstacle for a fundamentality-oriented formulation of physicalism: ‘the problem (...)
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  18. Mereological Harmony.Gabriel Uzquiano - 2008 - In Dean W. Zimmerman (ed.), Oxford Studies in Metaphysics. Oxford University Press.
    This paper takes a close look at the thought that mereological relations on material objects mirror, and are mirrored by, parallel mereological relations on their exact locations. This hypothesis is made more precise by means of a battery of principles from which more substantive consequences are derived. Mereological harmony turns out to entail, for example, that atomistic space is an inhospitable environment for material gunk or that Whiteheadian space is not a hospitable environment for unextended material atoms.
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  19.  97
    Tagging: semantics at the iconic/symbolic interface.Gabriel Greenberg - 2019 - In Julian J. Schlöder, Dean McHugh & Floris Roelofsen (eds.), Proceedings of the 22nd Amsterdam Colloquium. pp. 11-20.
    Tagging is the phenomenon in which regions of a picture, map, or diagram are annotated with words or other symbols, to provide descriptive information about a depicted object. The interpretive principles that govern tagged images are not well understood, due in part to the difficulty of integrating pictorial and linguistic semantic rules. Rather than directly combining these rules, I propose to use the framework of perspectival feature maps as an intermediary representation of content, in which the outputs of pictorial and (...)
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  20. Recombination and Paradox.Gabriel Uzquiano - 2015 - Philosophers' Imprint 15.
    The doctrine that whatever could exist does exist leads to a proliferation of possibly concrete objects given certain principles of recombination. If, for example, there could have been a large infinite number of concrete objects, then there is at least the same number of possibly concrete objects in existence. And further cardinality considerations point to a tension between the preceding doctrine and the Cantorian conception of the absolutely infinite. This paper develops a parallel problem for a variety of possible worlds (...)
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  21.  34
    Ethical perceptions of business students in a New Zealand university: do gender, age and work experience matter?Gabriel Eweje & Margaret Brunton - 2009 - Business Ethics: A European Review 19 (1):95-111.
    Ethical issues at the workplace have once again become topical and important due to considerable adverse publicity surrounding reports of unethical business practices by corporate managers. Accordingly, this paper re‐visits the question of whether gender, age and work experience do have an effect on ethical judgement, using 655 business students as respondents. This is necessary as business students are likely to become managers during their career and will face complex ethical concerns and dilemmas in their daily, routine affairs. The findings (...)
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  22.  40
    Emil du Bois-Reymond: Neuroscience, Self, and Society in Nineteenth-Century Germany.Gabriel Finkelstein - 2013 - The MIT Press.
    This biography of Emil du Bois-Reymond, the most important forgotten intellectual of the nineteenth century, received an Honorable Mention for History of Science, Medicine, and Technology at the 2013 PROSE Awards, was shortlisted for the 2014 John Pickstone Prize (Britain's most prestigious award for the best scholarly book in the history of science), and was named by the American Association for the Advancement of Science as one of the Best Books of 2014. -/- In his own time (1818–1896) du Bois-Reymond (...)
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  23. Ethical perceptions of business students in a new zealand university: Do gender, age and work experience matter?Gabriel Eweje & Margaret Brunton - 2009 - Business Ethics, the Environment and Responsibility 19 (1):95-111.
    Ethical issues at the workplace have once again become topical and important due to considerable adverse publicity surrounding reports of unethical business practices by corporate managers. Accordingly, this paper re-visits the question of whether gender, age and work experience do have an effect on ethical judgement, using 655 business students as respondents. This is necessary as business students are likely to become managers during their career and will face complex ethical concerns and dilemmas in their daily, routine affairs. The findings (...)
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  24.  24
    The Virtuous Manager: A Vision for Leadership in Business.Gabriel Flynn - 2008 - Journal of Business Ethics 78 (3):359-372.
    This article seeks to contribute to a vision for leadership in business based on a recovery of virtue. The vision for leadership articulated here draws principally on the writings of the classical philosopher Aristotle and of the contemporary philosopher Josef Pieper. Without discounting the ever-increasing complexity of modern business, this essay will attempt to reconstruct Aristotle’s emphasis on virtue and moral character, and argues for the philosopher’s relevance to modern management and corporate leadership. The paper concludes that the message of (...)
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  25.  25
    No Man’s Land: Exploring the Space between Gilligan and Kohlberg.Gabriel D. Donleavy - 2008 - Journal of Business Ethics 80 (4):807-822.
    The Kohlberg Gilligan Controversy has received intermittent but inconclusive attention for many years, perhaps reflecting the difficulty of bridging the two positions. This article explores the published evidence for Gilligan's claims of gender difference, gender identity difference, and role of caring in people's ethics. It seems that the evidence for pronounced gender differences in ethical attitudes within business is weak, even if gender identity is used instead of physical gender. The main propositions of Care Theory and recent advances in its (...)
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  26. Mereology and modality.Gabriel Uzquiano - 2014 - In Shieva Kleinschmidt (ed.), Mereology and Location. Oxford: Oxford University Press. pp. 33-56.
    Do mereological fusions have their parts necessarily? None of the axioms of non-modal formulations of classical mereology appear to speak directly to this question. And yet a great many philosophers who take the part-whole relation to be governed by classical mereology seem to assume that they do. In addition to this, many philosophers who make allowance for the part-whole relation to obtain merely contingently between a part and a mereological fusion tend to depart from non-modal formulations of classical mereology at (...)
     
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  27. Unreflective action and the argument from speed.Gabriel Gottlieb - 2011 - Pacific Philosophical Quarterly 92 (3):338-362.
    Hubert Dreyfus has defended a novel view of agency, most notably in his debate with John McDowell. Dreyfus argues that expert actions are primarily unreflective and do not involve conceptual activity. In unreflective action, embodied know-how plays the role reflection and conceptuality play in the actions of novices. Dreyfus employs two arguments to support his conclusion: the argument from speed and the phenomenological argument. I argue that Dreyfus's argumentative strategies are not successful, since he relies on a dubious assumption about (...)
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  28. Toward a Theory of Concept Mastery: The Recognition View.Gabriel Oak Rabin - 2020 - Erkenntnis 85 (3):627-648.
    Agents can think using concepts they do not fully understand. This paper investigates the question “Under what conditions does a thinker fully understand, or have mastery of, a concept?” I lay out a gauntlet of problems and desiderata with which any theory of concept mastery must cope. I use these considerations to argue against three views of concept mastery, according to which mastery is a matter of holding certain beliefs, being disposed to make certain inferences, or having certain intuitions. None (...)
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  29.  48
    Frege als Neukantianer.Gottfried Gabriel - 1986 - Kant Studien 77 (1-4):84-101.
  30.  34
    Mereological Harmony 1.Gabriel Uzquiano - 2011 - Oxford Studies in Metaphysics 6.
    This chapter takes a close look at the thought that mereological relations on material objects mirror, and are mirrored by, parallel mereological relations on their exact locations. This hypothesis is made more precise by means of a battery of principles from which more substantive consequences are derived. Mereological harmony turns out to entail, for example, that atomistic space is an inhospitable environment for material gunk or that Whiteheadian space is not a hospitable environment for unextended material atoms.
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  31. Mereological Harmony.Gabriel Uzquiano - 2011 - In Karen Bennett & Dean W. Zimmerman (eds.), Oxford Studies in Metaphysics Volume 6. Oxford, GB: Oxford University Press.
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  32.  29
    Ethical Analysis of “Mind Reading” or “Neurotechnological Thought Apprehension”: Keeping Potential Limitations in Mind.Peter Zuk & Gabriel Lázaro-Muñoz - 2019 - American Journal of Bioethics Neuroscience 10 (1):32-34.
    We appreciate Meynen’s examination of ethical implications of using neurotechnologies to decode neural data and make inferences about cognitive processes. Here, we address three issues that we beli...
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  33. Creative fidelity.Gabriel Marcel - 1964 - New York: Fordham University Press. Edited by Robert Rosthal.
    This important collection of lectures and essays was regarded by Gabriel Marcel as the best introduction to his thought.
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  34.  37
    The Role of MNEs in Community Development Initiatives in Developing Countries.Gabriel Eweje - 2006 - Business and Society 45 (2):93-129.
    Multinational enterprises (MNEs) have long had a reputation of not doing enough for their host communities in developing countries. This study critically examines the role of MNEs in community development initiatives in developing countries, using the Nigeria oil industry and the South African mining industry as case study. Specifically, the study assessed the usefulness of MNE-supported community development projects as a means of demonstrating corporate social responsibility. The findings suggest that expectations for community development projects are greater in developing countries. (...)
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  35. Elusive Propositions.Gabriel Uzquiano - 2021 - Journal of Philosophical Logic 50 (4):705-725.
    David Kaplan observed in Kaplan that the principle \\) cannot be verified at a world in a standard possible worlds model for a quantified bimodal propositional language. This raises a puzzle for certain interpretations of the operator Q: it seems that some proposition p is such that is not possible to query p, and p alone. On the other hand, Arthur Prior had observed in Prior that on pain of contradiction, ∀p is Q only if one true proposition is Q (...)
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  36.  29
    Functions and Generality of Logic: Reflections on Dedekind's and Frege's Logicisms.Gabriel Sandu, Marco Panza & Hourya Benis-Sinaceur (eds.) - 2015 - Cham, Switzerland: Springer Verlag.
    Part I of Frege’s Grundgesetze is devoted to the “exposition [Darlegung]” of his formal system.
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  37. Conceptual mastery and the knowledge argument.Gabriel Rabin - 2011 - Philosophical Studies 154 (1):125-147.
    According to Frank Jackson’s famous knowledge argument, Mary, a brilliant neuroscientist raised in a black and white room and bestowed with complete physical knowledge, cannot know certain truths about phenomenal experience. This claim about knowledge, in turn, implies that physicalism is false. I argue that the knowledge argument founders on a dilemma. Either (i) Mary cannot know the relevant experiential truths because of trivial obstacles that have no bearing on the truth of physicalism or (ii) once the obstacles have been (...)
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  38.  14
    The ethics of positive thinking in healthcare.Gabriel Andrade - 2019 - Journal of Medical Ethics and History of Medicine 12.
    In continuation with the New Thought movement that arose in the United States in the 19th Century, there is now a massive self-help industry that markets books and seminars. This industry has also extended to healthcare in the form of positive thinking, i.e., the idea that happy thoughts are essential for health. While some of these claims may seem reasonable and commonsensical, they are not free of problems. This article posits that positive thinking has some ethical underpinnings. Extreme positive thinking (...)
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  39. Know-How, procedural knowledge, and choking under pressure.Gabriel Gottlieb - 2015 - Phenomenology and the Cognitive Sciences 14 (2):361-378.
    I examine two explanatory models of choking: the representationalist model and the anti-representationalist model. The representationalist model is based largely on Anderson's ACT model of procedural knowledge and is developed by Masters, Beilock and Carr. The antirepresentationalist model is based on dynamical models of cognition and embodied action and is developed by Dreyfus who employs an antirepresentational view of know-how. I identify the models' similarities and differences. I then suggest that Dreyfus is wrong to believe representational activity requires reflection and (...)
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  40. Ramified structure.Gabriel Uzquiano - 2022 - Philosophical Studies 180 (5-6):1651-1674.
    The Russell–Myhill theorem threatens a familiar structured conception of propositions according to which two sentences express the same proposition only if they share the same syntactic structure and their corresponding syntactic constituents share the same semantic value. Given the role of the principle of universal instantiation in the derivation of the theorem in simple type theory, one may hope to rehabilitate the core of the structured view of propositions in ramified type theory, where the principle is systematically restricted. We suggest (...)
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  41.  26
    The need for “gentle medicine” in a post Covid-19 world.Gabriel Andrade & Maria Campo Redondo - 2021 - Medicine, Health Care and Philosophy 24 (4):475-486.
    As it has historically been the case with many pandemics, the Covid-19 experience will induce many philosophers to reconsider the value of medical practice. This should be a good opportunity to critically scrutinize the way medical research and medical interventions are carried out. For much of its history, medicine has been very inefficient. But, even in its contemporary forms, a review of common protocols in medical research and medical interventions reveal many shortcomings, especially related to methodological flaws, and more importantly, (...)
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  42.  36
    The philosophy of existentialism.Gabriel Marcel - 1956 - New York,: Citadel Press.
    An exposition in five parts of the character of existentialist philosophy, including an analysis of the theories of Jean-Paul Sartre. Author Gabriel Marcel, a famous French dramatist, philosopher, and author of Le Dard, was a leading exponent of Christian existentialism.
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  43.  20
    Fichte's Foundations of Natural Right: A Critical Guide.Gabriel Gottlieb (ed.) - 2016 - Cambridge University Press.
    Fichte's Foundations of Natural Right was one of the most influential books in nineteenth-century philosophy. It was read carefully by Schelling, Hegel, and Marx, and initiated a tradition in German philosophy that considers human subjectivity to be relational and intersubjective, thus requiring relations of recognition between subjects. The essays in this volume highlight this little-understood book's most important ideas and innovations. They offer discussions of Fichte's conception of freedom, self-consciousness, coercion, the summons, the body, and human rights, together with new (...)
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  44. Before Effect Without Zeno Causality.Gabriel Uzquiano - 2012 - Noûs 46 (2):259-264.
    We argue that not all cases of before-effect involve causation and ask how to demarcate cases of before-effect in which the events that follow exert causal influence over the before-effect from cases in which they do not.
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  45.  32
    O contrato racial, de Charles Wade Mills.Gabriel Silveira de Andrade Antunes - 2023 - Cadernos de Ética E Filosofia Política 42 (2):124-128.
    Resenha de "O contrato racial" de Charles W. Mills.
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  46.  18
    Moral Repair: Toward a Two-Level Conceptualization.Jordi Vives-Gabriel, Wim Van Lent & Florian Wettstein - 2023 - Business Ethics Quarterly 33 (4):732-762.
    Moral repair is an important way for firms to heal moral relationships with stakeholders following a transgression. The concept is rooted in recognition theory, which is often used to develop normative perspectives and prescriptions, but the same theory has also propelled a view of moral repair as premised on negotiation between offender and victim(s), which involves the complex social construction of the transgression and the appropriate amends. The tension between normative principles and socioconstructivist implementation begs the question how offending firms (...)
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  47.  77
    Tragic wisdom and beyond.Gabriel Marcel - 1973 - Evanston,: Northwestern University Press. Edited by Paul Ricœur, Stephen Jolin & Peter McCormick.
    This volume presents two works by Gabriel Marcel.
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  48.  13
    Essai de philosophie concrète.Gabriel Marcel - 1967 - [Paris]: Gallimard.
    La singularité de la démarche philosophique de Gabriel Marcel vient de ce qu'elle renoue avec ses origines socratiques ; elle se fonde résolument sur le concret, c'est-à-dire le corps-propre (par oposition au corps-objet ou instrument), la sensation traitée comme manière d'être au monde plutôt que comme message, la mémoire, la volonté.
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  49.  8
    Capitalism & ethics.Gabriel Flynn, Michael Aßländer & Daryl Koehn - 2023 - Business Ethics, the Environment and Responsibility 32 (S1):1-3.
    Business Ethics, the Environment &Responsibility, Volume 32, Issue S1, Page 1-3, April 2023.
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  50.  54
    Mastering Mary.Gabriel Oak Rabin - 2019 - American Philosophical Quarterly 56 (4):361-370.
    I make three claims about the interactions between concept mastery and the knowledge argument. First, I argue that, contra Ball, the concept mastery response to the knowledge argument does not suffer from the heterogeneity of concept mastery. Second, I argue that, when doing metaphysics by relating propositions on the basis of whether a hypothetical agent who knew a base collection could infer a target proposition, it is legitimate to rely on propositions that are not contained in the base, as long (...)
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