How different neural crest derivatives differentiate in distinct embryonic locations in the vertebrate embryo is an intriguing issue. Many attempts have been made to understand the underlying mechanism of specific pathway choices made by migrating neural crest cells. In this speculative review we suggest a new mechanism for the regulation of neural crest cell migration patterns in avian and mammalian embryos, based on recent progress in understanding the expression and activity of receptor tyrosine kinases during embryogenesis. Distinct subpopulations of crest‐derived (...) cells express specific receptor tyrosine kinases while residing in a migration staging area. We postulate that the differential expression of receptor tyrosine kinases by specific subpopulations of neural crest cells allows them to respond to localized growth factor ligand activity in the embryo. Thus, the migration pathway taken by neural crest subpopulations is determined by their receptor tyrosine kinase response to the differential localization of their cognate ligand. (shrink)

Meaningful relationships are centrally important for human functioning. It remains unclear, however, which aspects of meaningful relationships impact wellbeing the most and whether these differ between psychiatric patients and members of the community. Information about relationship attributes and functions were collected in community members and psychiatric patients. Relationship attributes and functions were examined for differences between groups, their impact on wellbeing and symptoms, and the size of network. Community members reported fewer relationships, higher frequency of contact and less desire for (...) change when compared to the psychiatric patients. Nevertheless, both groups reported relatively high levels of fulfilled functions. Quality of the relationship and investment into the relationship was associated with both wellbeing and symptoms for both the community and the patient group. Almost all functions were associated with wellbeing and symptoms for the community group. However, for the patient group, only few functions were associated with wellbeing and no functions were associated with symptoms. Contrary to our hypotheses, the results show that psychiatric patients do not have a deficit in fulfilling relationships. Most people report a well-functioning network of meaningful, high-quality relationships. Patients benefit from meaningful, function-fulfilling relationships just as much as community members. Results are discussed with respect to how targeting relationships can be used clinically. (shrink)

Bd. 1. Abhandlungen zur Psychologie, bearb. von R. Kindinger und R. Haller.--Bd. 2. Abhandlungen zur Erkenntnistheorie und Gegenstandstheorie, bearb. von R. Haller.--Bd. 3. Abhandlungen zur Werttheorie, bearb. von R. Kindinger.--Bd. 4. über Annahmen.--Bd. 5. Über philosophische Wissenschaft und ihre Propädeutik. Über die Stellung der Gegenstandstheorie im System der Wissenschaften. Über die Erfahrungsgrundlagen unseres Wissens. Zum Erweise des allgemeinen Kausalgesetzes, bearb. von R.M. Chisholm.--Bd. 6. Über Möglichkeit und Wahrscheinlichkeit, bearb. von R.M. Chisholm.--7. Selbstdarstellung. Vermischte Schriften, bearb. von R. (...) class='Hi'>Haller. (shrink)

Our article attempts to provide some clarity to the debate about the proper relationship between science and public policy by drawing on the philosophical field of logic. We argue that based on an analysis of the most fundamental ways that empirical and evaluative truth claims can be used together in arguments, the tendency to conceive of this relationship either in dual terms of “pure” vs. “applied” or complex “multi-disciplinary” or “multi-cultural” systems of categorization should be rejected in favor a basic (...) four-part division. A significantly improved understanding of the connection between science and public policy can be based on an examination of the four most basic kinds of logical connection between empirical and evaluative statements. One such improvement is a better understanding of how funding should be divided between state and private interests. (shrink)

Gesamtinhaltverzeichnis: Vorwort (Rudolf Haller). -Einleitung (Rudolf Haller). - Editorische Vorbemerkung (Thomas Binder). - I. Herbert Feigl: Zufall und Gesetz. - II. Marcel Natkin: Einfachheit, Kausalitaet und Induktion. - III. Tscha Hung: Das Kausalproblem in der heutigen Physik.".

Every domain-specific ontology must use as a framework some upper-level ontology which describes the most general domain-independent categories of reality. In the present paper we sketch a new type of upper-level ontology, and we outline an associated knowledge modelling language called GOL – for: General Ontological Language. It turns out that the upper-level ontology underlying well-known standard modelling languages such as KIF, F-Logic and CycL is restricted to the ontology of sets. In a set theory which allows Urelements, however, there (...) will be ontological relations between these Urelements which the set-theoretic machinery cannot capture. In contrast to standard modelling and representation formalisms, GOL provides a machinery for representing and analysing such ontologically basic relations. GOL is thus a genuine extension of KIF and of similar languages. In GOL entities are divided into sets and Urelements, the latter being divided in their turn into individuals and universals. Foremost among the individuals are things or substances, tropes or moments, and situoids: entities containing facts as components. (shrink)

Hypothesis-driven approaches identified important characteristics that differentiate violent from non-violent radicals. However, they produced a mosaic of explanations as they investigated a restricted number of preselected variables. Here we analyzed without a priory assumption all the variables of the “Profiles of Individual Radicalization in the United States” database by a machine learning approach. Out of the 79 variables considered, 19 proved critical, and predicted the emergence of violence with an accuracy of 86.3%. Typically, violent extremists came from criminal but not (...) radical backgrounds and were radicalized in late stages of their life. They were followers in terrorist groups, sought training, and were radicalized by social media. They belonged to low social strata and had problematic social relations. By contrast, non-violent but still criminal extremists were characterized by a family tradition of radicalism without having criminal backgrounds, belonged to higher social strata, were leaders in terrorist organizations, and backed terrorism by supporting activities. Violence was also promoted by anti-gay, Sunni Islam and Far Right, and hindered by Far Left, Anti-abortion, Animal Rights and Environment ideologies. Critical characteristics were used to elaborate a risk-matrix, which may be used to predict violence risk at individual level. (shrink)

Wittgenstein, possibly the most influential philosopher of the twentieth century, is often labelled a Neopositivist, a New-Kantian, even a Sceptic. _Questions on Wittgenstein_, first published in 1988, presents a selection of nine essays investigating a matter of vital philosophical importance: Wittgenstein’s relationship to his Austrian predecessors and peers. The intention throughout is to determine the precise contours of Wittgenstein’s own thought by situating it within its formative context. Although it remains of particular interest to Anglo-Saxon philosophers, special familiarity with Austrian (...) philosophy is required to appreciate the subtle and profound influence which this cultural and philosophical setting had on Wittgenstein’s intellectual development. Professor Haller has spent his career exploring these themes, and is one of the foremost authorities on both Wittgenstein and contemporary Austrian philosophy. Questions on Wittgenstein thus offers a unique insight into the twentieth-century tradition of Austrian philosophy, and its importance for Wittgenstein’s thought. (shrink)

Wittgenstein, possibly the most influential philosopher of the twentieth century, is often labelled a Neopositivist, a New-Kantian, even a Sceptic. Questions on Wittgenstein , first published in 1988, presents a selection of nine essays investigating a matter of vital philosophical importance: Wittgenstein’s relationship to his Austrian predecessors and peers. The intention throughout is to determine the precise contours of Wittgenstein’s own thought by situating it within its formative context. Although it remains of particular interest to Anglo-Saxon philosophers, special familiarity with (...) Austrian philosophy is required to appreciate the subtle and profound influence which this cultural and philosophical setting had on Wittgenstein’s intellectual development. Professor Haller has spent his career exploring these themes, and is one of the foremost authorities on both Wittgenstein and contemporary Austrian philosophy. Questions on Wittgenstein thus offers a unique insight into the twentieth-century tradition of Austrian philosophy, and its importance for Wittgenstein’s thought. (shrink)

Attentional control theory suggests that high cognitive demands impair the flexible deployment of attention control in anxious adults, particularly when paired with external threats. Extending this...

In the judgment of many historians of contemporary philosophy as well as of analytic philosophers of different lines, there is no doubt about the truth of the statement that the philosophy of the Vienna Circle is dead. And since it is dead, some think that the only remaining task could be to find out the cause that led to the downfall of this proud philosophical movement.

This volume, originating from the centennial Second International Conference Graz 1977-2017 on Franz Brentano's philosophy, collects eighteen essays written by nineteen distinguished specialists covering the main areas of Brentano's philosophy: his epistemology, ontology, ethics, and logic, and his contributions to psychology and philosophy of mind. Its goal is to explore the significance and impact of Brentano's thought, to promote a deepening of the ongoing renaissance of interest in Brentano, and to advance the project of understanding Brentano's actual philosophical positions and (...) correcting entrenched misunderstandings. (shrink)

Distributional fairness of corporate distributions is an important social issue linked to accounting for equality. Value added and the information contained in the value added statement can conceptually be regarded as a reflection of how the company is managed for all stakeholders. We investigate value added information published in sustainability reports to determine if the information provided is useful for assessing distributional fairness between stakeholders. We find that the value added information disclosed lack conciseness, comparability and understandability. The divergence is (...) considerable and the explanations of the disclosed information so limited that the usefulness of the value added disclosures must be questioned. Our results suggest several obfuscating techniques in the disclosure of value added information, including disclosing information that is conceptually compromised, resulting in comparability issues and disclosing information that can’t be verified by reconciling back to the financial statements. Our findings have clear ethical and moral implications as they stress the societal issue of distributional fairness. It seems that companies are either reluctant to provide value added information that is useful, or deliberately use value added disclosures to obfuscate. Information reflecting distributional fairness is therefore compromised. (shrink)