BackgroundBoth impairment and sex differences in social cognition and neurocognition have been documented in schizophrenia. However, whether sex differences exist in the association between social cognition and neurocognition are not known. We aimed to investigate the contribution of areas of neurocognition to theory of mind and hostility bias, representing social cognition, according to sex in early course schizophrenia.MethodsIn this cross-sectional study, we assessed neurocognition using the Japanese version of the Brief Assessment of Cognition in Schizophrenia and assessed the ToM and (...) hostility bias subdomains of social cognition using the Social Cognition Screening Questionnaire in 131 participants diagnosed with schizophrenia within 5 years of onset. Sex differences were analyzed using t-tests. The associations of neurocognitive subdomains with ToM and hostility bias according to sex were analyzed using multiple regression analysis. Results were adjusted by age, estimated premorbid intelligence quotient, and symptomatology.ResultsNo sex differences were found in ToM or hostility bias. Higher verbal fluency was significantly associated with higher ToM in females, whereas higher executive function was significantly associated with higher ToM in males. Higher verbal fluency was significantly associated with lower hostility bias in females, whereas neurocognition and hostility bias were not significantly associated in males.ConclusionThe results suggest that neurocognition associated with social cognition differ according to sex. These differences should be considered for more effective treatment of social cognition. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Religion and Science: Nishitani’s View of Nihility and Emptiness–A Pure Land Buddhist CritiqueRyusei TakedaIn general, philosophical critique of Nishida, Tanabe, and Nishitani, the so-called Kyoto school, has been mainly conducted from a Zen Buddhist perspective. One should not, however, overlook the fact that a profound regard for the philosophical aspects of Pure Land Buddhist thought, another major stream of Mahayana Buddhism, is deeply intertwined in the foundation of their (...) philosophies. But the ways in which they interpret it and the position they give it within their philosophical systems are not the same: they have taken different forms, often giving rise to original terminology, in accord with each thinker’s metaphysical speculation.As Alfred N. Whitehead critically argues in his Religion in the Making, the fundamental reason for the decay of both Buddhism and Christianity is that “each religion has unduly sheltered itself from the other. The self-sufficient pedantry of learning and the confidence of ignorant zealots have combined to shut up each religion in its own forms of thought. Instead of looking to each other for deeper meanings, they have remained self-satisfied and unfertilized.” Further, “both have suffered from the rise of the third tradition, which is science, because neither of them had retained the requisite flexibility of adaptation.” 1In this contemporary situation, the philosophies of Nishida, Tanabe, and Nishitani, in which the issue of religion and science has been brought into fundamental question and examined on the dimension of origin of their development, have extremely important implications for the critical interpretation of Pure Land Buddhist doctrines, particularly in the postmodern world. 2There are two points I want to make in this paper. First, the fundamental structure of Pure Land Buddhism, in a way an antipode to Zen, will be examined in light of Nishitani’s metaphysical analysis of the relationship between human experience and the laws of nature, particularly bringing into focus his existential realization of ‘nihility.’And second, I want to challenge Nishitani’s understanding of ‘emptiness’ from my perspective as a Pure Land Buddhist, and also to uncover some fundamental [End Page 155] problems underlying his view of ‘emptiness’ by attempting to relate it to Nagarjuna’s negation of ‘substance’ in his concept of ‘non-self being,’ or ‘nih-svabhava.’ 3What is Religion for Nishida, Tanabe, and Nishitani?Before getting into those two topics, I want to make a rough sketch indicating about where Nishida, Tanabe, and Nishitani see that religious experience is to be truly realized.The starting point of Nishida’s understanding of religion is found in his argument that “it is on the ground of fact that religion ought to be considered.” The fact of religious experience is in his view none other than self-awareness of ‘absolute nothingness,’ which is also the foundation of what we consider as objective knowledge. The self-awareness manifests itself in the midst of such fact and serves to reveal that fact. He argues that the ultimate goal of Mahayana Buddhism is to penetrate into the depth of this fact.In Tanabe’s philosophy, one’s resurrection and return to the world (genso) and self-renunciation through ‘metanoetics’ (zangedo), a philosophy of absolute Other-power, are required and witnessed to in order for one to establish a genuine religious standpoint. Neither/nor, instead of both/and, is the only relationship in which the self negates itself by means of contradiction, so that at the same time as the self is extinguished in the negation, the contradiction of that which opposes the self is also extinguished. Converted into the neither/nor relationship, both self and contradiction cease to be contradictory opposites. 4 This is Tanabe’s criticism directed at Nishida’s notion of the self-identity of absolute contradiction. Nothingness can never be intuited as such self-identity. The self-consciousness of nothingness is only in resurrection and return to the world, which is witnessed to through practice based upon faith and performed in obedience to Other-power. 5For Nishitani the question of the essence of religion must be answered through tracing the process of the genuine pursuit of true reality. He attempts to interpret the religious quest... (shrink)

Après un bref survol de l’esthétique britannique au xxe siècle, les objections de Wollheim à la théorie « idéelle » de l’art, qu’il attribue à Croce et à Collingwood, sont présentées. Dans une deuxième partie, les critiques de Bosanquet à l’endroit de la théorie de Croce sont examinées, pour en conclure qu’on ne peut pas lui attribuer la théorie « idéelle ». Il en va de même pour Collingwood, dont les grandes lignes de son esthétique sont présentées dans la troisième (...) partie, dont le but accessoire est de montrer que sa théorie est par ailleurs plus satisfaisante que celle de Bosanquet ; elle est en réalité très proche de celle de Wollheim, malgré les dires de ce dernier. Dans la conclusion, on revient sur le motif des théories de l’art des idéalistes britanniques, à savoir le rôle social que doit jouer l’oeuvre d’art, pour montrer toute l’actualité de la théorie de Collingwood, pour qui l’oeuvre d’art est le produit non pas de l’artiste seul, mais de l’artiste et de son audience.After a brief survey of British aesthetics in the XXth century, Wollheim’s objections to the ‘ideal’ theory, which he imputes to Croce and Collingwood, are presented. In the second part, Bosanquet’s critique of Croce’s theory is presented in order to show that one cannot attribute to him the ‘ideal’ theory. The same goes for Collingwood, whose aesthetic theory is sketched in the third part, which argues accessorily that it is more satisfactory than Bosanquet’s ; it is in fact, his own claims to the contrary notwithstanding, rather close to Wollheim’s. The conclusion comes back to the central motivation for British Idealist theories of art, namely that the work of art has a social role to play, in order to show the actuality of Collingwood, who viewed the work of art not as the product of the artist alone, but from the artist and the audience alike. (shrink)

The title of Marnie Hughes-Warrington's study, 'How Good an Historian Shall I Be?', is taken from a 1930 pam-phlet by Collingwood, in which, assuming that 'there are as many historians as there are human beings', he inferred that 'the question is not 'Shall I be an historian or not?' but How good an historian shall I be?'' . Hughes-Warrington takes this to be 'probably the most important question we can ask' . Indeed, she believes that 'historical education' is 'a duty (...) that we all must bear for our sake and for the sake of civilisation' . Hughes-Warrington thus situates proper histori-cal education within the wider process of civilization; this leitmotif being taken from Collingwood, for whom educa-tion is the means 'by which a civilisation keeps itself alive from one generation to the next'. (shrink)

In particular, as we shall see, Collingwood is often dismissed as having held an indefensible, outmoded ‘ideal’ theory, according to which the work of art is primarily ‘mental’, while his potential role in current debates is simply ignored. I will argue that this view is largely mistaken.

In this chapter, Kobayashi and Marion first provide reasons to reject the many readings of Collingwood that sought to draft him as a participant in the Hempel-Dray debate about the status of covering laws in history. After all, this debate was not part of Collingwood’s context and, although one can pry from his writings a contribution to it, one may simply, by doing so, misunderstand what he was up to. In the second part, they present the Gabbay-Woods Schema for abductive (...) reasoning, as it occurs in the context of inquiry, as triggered by an ignorance problem, and as being ‘ignorance preserving’. They then argue that this allows us better to see the point of Collingwood’s ‘logic of questions and answers’, as derived from his own practice in archaeology, and his use of the ‘detective model of the historian’, as opposed to merely focussing on understanding what ‘re-enactment’ could mean as a contribution to the Hempel-Dray debate. (shrink)

TOPOLOGIE DES LOGOS UND KANT-INTERPRET A TION § I. Topologie des Logos Die Geschichte der Philosophie ist die Geschichte der Entwicklung des Logos. Jedes System der Philosophie hat seinen Logos. Jedes System der Philosophie, welches seinen Logos hat, ist vom Standpunkte der Entwicklung der Philosophie als Ganzem gesehen eine notwendige Entwicklung des Logos. Die Geschichte der Philosophie ist, wie Hegel sagte, eine Entwicklung des absoluten Geistes. Aber diese Entwicklung des Logos soll man nicht als dialektische Entwicklung, wie Hegel sie sah, (...) bezeichnen. Vielmehr befindet sich das System der Hegelschen Philosophie selber an einer besonderen Stelle der Entwicklung des Logos. Die Entwicklung des Logos ist nicht immer dialektisch-formelle Entwicklung und wird nicht in Dialektik bis zum Äußersten getrieben. Wir müssen uns davor hüten, die Entwicklung des Logos formell dialek tisch zu sehen. Vielmehr müssen wir die Entwicklung des Logos - in der Phase der notwendigen Entwicklung, in der er sich befinde- positiv betrachten. Dialektische Konstruktion der Geschichte der Philosophie auf Kosten der Tatsachen, wie Hegel sie trieb, ist dogma tisch-idealitisches Verhalten, und unser Verhalten soll nicht solches sein. Betrachten wir positiv die Entwicklung des Logos in der Geschich te der Philosophie, so entsteht nicht dialektische Geschichtsauffassung, sondern Topologie der Entwicklung des Logos: kurz, die Topologie des Logo::. Nach der Topologie des Logos wird jedem System der Philoso phie sein Topos in der Entwicklung des Logos als Ganzem gegeben. (shrink)

Replication forks inevitably stall at damaged DNA in every cell cycle. The ability to overcome DNA lesions is an essential feature of the replication machinery. A variety of specialized polymerases have recently been discovered, which enable cells to replicate past various forms of damage by a process termed translesion synthesis. Alternatively, homologous recombination can be used to restart DNA replication across the lesion. Genetic and biochemical studies have shed light on the impact of these two post‐replication repair pathways in bacteria (...) and yeast. In vertebrates, however, a genetic approach to study post‐replication repair has been compromised because many of the genes involved appear to be essential for embryonic development. We have taken advantage of the chicken cell line DT40 to perform a genetic analysis of translesion synthesis and homologous recombination and to characterize genetic interactions between these two pathways in vertebrates. In this article, we aim to summarize our current understanding of post‐replication repair in DT40 in the perspective of bacterial, yeast and mammalian genetics. BioEssays 26:151–158, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

This book constitutes the thoroughly refereed joint post-proceedings of three international workshops organized by the Japanese Society for Artificial Intelligence, held in Tokyo, Japan in June 2006 during the 20th Annual Conference JSAI 2006. The volume starts with eight award winning papers of the JSAI 2006 main conference that are presented along with the 21 revised full workshop papers, carefully reviewed and selected for inclusion in the volume.

The aim of this paper is to propose an antithesis to the overreliance on scientific facts and objectivity to counter mis- and disinformation in media literacy education. Through conceptual examination of meaning, care, and facts, I demonstrate the ontological priority of meaning and values in the life-world. I then discuss conspiracy theories as a textual genre in which the crisis of meaning manifests as a prominent factor. Given the centrality of meaning, I claim that literacy education needs to go beyond (...) the matters of fact and address matters of concern in this supposedly post-truth world. (shrink)