Most growth models for complex networks consider networks comprising a single connected block or island, which contains all the nodes in the network. However, it has been demonstrated that some large complex networks have more than one island, with an island size distribution obeying a power-law function Is~s-α. This paper introduces a growth model that considers the emergence of islands as the network grows. The proposed model addresses the following two features: the probability that a new island is generated decreases (...) as the network grows and new islands are created with a constant probability at any stage of the growth. In the first case, the model produces an island size distribution that decays as a power-law Is~s-α with a fixed exponent α=1 and in-degree distribution that decays as a power-law Qi~i-γ with γ=2. When the second case is considered, the model describes island size and in-degree distributions that decay as a power-law with 2<α<∞ and 2<γ<∞, respectively. (shrink)

La presente investigación pretende analizar someramente el derecho a la verdad haciendo hincapié en su acepción extrajudicial y, en particular, en la memoria histórica que ha sido abordada mediante la sentencia T - 281 del 2021, en la que en consecuencia al proceso instaurado por el general Marcos Evangelista Pinto Lizarazo en contra del mural urbano ¿Quién dio la orden? Se evidencia la protección constitucional del derecho a la memoria histórica en virtud del pronunciamiento de la Corte Constitucional.

La relación entre seres humanos y otros anymales (anymals) (Kemmerer, 2006) es, por definición, asimétrica. A lo largo de la historia se han esgrimido múltiples argumentos para justificar un supuesto excepcionalismo humano (excepcionalism), desde la atribución de derechos divinos a una mayor inteligencia, legitimando así un sistema de explotación denominado dominación (domination) (Manfredo et al. 2019). Las relaciones entre especies y cómo se conciben son un tema difícil. Hay muchos modos de enfocar las relaciones entre el humano y los anymales, (...) desde la adoración religiosa (vacas en la India) a la explotación (investigación biomédica). Además en Occidente surgen formas alternativas de ver y entender estas relaciones (por ejemplo, la relación con animales domésticos). La pertenencia a una u otra especie es un factor fundamental que influye en la posición que cada animal tiene en estas jerarquías asimétricas. Sin embargo, se deben considerar otros elementos relevantes, como los vínculos entre individuos, de la misma manera que el afecto por otras personas depende en líneas generales del tipo de vínculo que tengamos con ellas (por ejemplo, la relaciones familiares o de amistad). (shrink)

El artículo procura mostrar las razones por las cuales no puede considerarse que la ética aristotélica sea determinista. De este modo, critica los argumentos de tres intérpretes que defienden el determinismo aristotélico: Alfredo Gómez-Muller, Theodor Gomperz y D.J. Furley, con el fi n de mostrar que la ética del Estagirita no está fundamentada en la necesidad sino en la convención, que el carácter no está totalmente determinado por naturaleza y que una vez éste se ha formado Aristóteles sí concibe la (...) posibilidad de cambio, si bien para ello se necesita mucho más que la mera intención. Con este análisis se pretende mostrar, entonces, más allá de la polémica particular con los intérpretes, que la ética aristotélica trata de explicar el mundo humano en su complejidad y riqueza y, por tanto, no puede considerarse determinista. (shrink)

Mirativity is a grammatical category or a linguistic strategy that makes explicit the surprising aspect of a piece of information. Different mirativity strategies appear in different languages. Evidentiality is a grammatical category that explicitly expresses the source of information, i.e. if something has been seen, heard or inferred. Whether mirativity forms part of evidentiality is an open question. An agent makes use of a mirativity marker when she or he expresses something about a surprising fact with respect to her or (...) his background knowledge. But there are different kinds of mirativity markers. Some of them are simple and direct and others, more complex, involve inferential processes. Here, we focus on complex mirativity and we compare it with inferred evidentials and deferred realizations. Our proposal goes beyond the purely linguistic analysis, since we try to interpret mirativity, and its role in interaction, as forming part of or involving a particular kind of inference, namely abduction. Mirativity can be used to express the surprising state that triggers an abductive reasoning but it can also encapsulate its result in such a way that it can be understood in relation to evidentiality. Thus, at least in some cases of complex mirativity, mirativity may convey indication about the source of information. Interesting for studies on dialogue is that they also indicate the degree of commitment of the speakers with the content of their own utterances. (shrink)

ISSN:1909-9711 (En línea) Misión La Revista Acta Colombiana de Psicología publica hallazgos originales de las investigaciones en Psicología y de esta disciplina en diálogo con otras, con el propósito de divulgarlas a la comunidad universitaria y a todas las personas interesadas en conocer sus nuevos avances y aplicaciones a distintos campos y necesidades de la sociedad contemporánea.

RESUMEN Cuando se mira la masacre de El Salado, es difícil no preguntarse por los factores que llevaron a esta comunidad de los Montes de María, en el contexto de la guerra rural que vivía Colombia a finales del siglo XX, a volverse un objetivo militar por parte de las A.U.C. (Autodefensas Unidas de Colombia), es decir, a recibir la marca o estigma de 'pueblo guerrillero'; en otras palabras, a convertirse en un pueblo masacrable. El presente artículo intenta abordar esta (...) cuestión y para ello analiza las consecuencias de la ocupación de las FARC desde su ingreso a la región en los noventa. Los modos como este poder fareano dispuso de lógicas guerreristas y dejó poco margen de maniobra y libertad para los pobladores de El Salado; los saladeros no tuvieron opción ni libertad, y la cohabitación se confundió con la colaboración, la pasividad con la pertenencia. En una segunda parte, revisa los efectos de la arremetida brutal de las FARC contra cierto grupo de pobladores (en especial, ganaderos y fuerza pública); de algún modo, la masacre del 2000, ejecutada por las AUC, fue una respuesta impulsada por un odio desmedido frente a una violencia también excesiva por parte de las FARC en los años anteriores a la masacre. En este apartado, se habla acerca del odio y la venganza que se constituyen en afectos que contribuyeron decisivamente -entre otros más- a la masacre del año 2000. Las elaboraciones sobre la economía del odio de Sara Ahmed (2015) y las de Laura Quintana sobre los afectos (2020 y 2021) serán fundamentales. ABSTRACT When looking at the El Salado massacre, we wonder about the factors that led this town of los Montes de María, in the context of the rural war in Colombia at the end of the 20th century, to become a military objective by the A.U.C (Autodefensas Unidas de Colombia), that is, to receive the brand or stigma of 'guerrilla people'; that is, to become a massacrable town. This article tries to address this issue, thus analyzing the consequences of the FARC occupation since its entry into the region in the nineties. Ways like this Farean power had warmer logic and left little room for maneuver and freedom for the residents of El Salado; The saladeros had no choice or freedom, and cohabitation was confused with collaboration, passivity with belonging. in a second part, it reviews the effects of the brutal attack by the FARC against a certain group of residents (especially, ranchers and the military); in a way, the 2000 massacre, carried out by the AUC, was an inordinately hateful response to excessive violence by the FARC in the years before the massacre. In this section, we talk about the hatred and revenge that constitute elements that contributed decisively -among others- to the 2000 massacre. The elaborations on the economy of hate by Sara Ahmed (2015) and the elaborations of Laura Quintana on affects (2020 and 2021) will be fundamental. (shrink)

Ciencias sociales : saberes coloniales y eurocéntricos / Edgardo Lander / - Europa modernidad y eurocentrismo / Enrique Dussel / - La colonialidad a lo largo y a lo ancho : el hemisferio occidental en el horizonte colonial de la modernidad / Walter D. Mignolo / - Naturaleza del poscolonialismo : del eurocentrismo al globocentrismo / Fernando Coronil / - El lugar de la naturaleza y la naturaleza del lugar : ¿globalización o postdesarrollo? / Arturo Escobar / - Ciencias sociales, (...) violencia epistémica y el problema de la invención del otro / Santiago Castro-Gómez / - Superar la exclusión, conquistar la equidad : reformas, políticas y capacidades en el ámbito social / Alejandro Moreno / - Abrir, impensar, y redimesionar las ciencias sociales en América Latina y el Caribe. ¿Es posible una ciencia social no eurocéntrica en nuestra región? / Francisco López Segrera / - Colonialidad del poder, eurocentrismo y América Latina / Aníbal Quijano. (shrink)

We extend the languages of both basic and graded modal logic with the infinity diamond, a modality that expresses the existence of infinitely many successors having a certain property. In both cases we define a natural notion of bisimilarity for the resulting formalisms, that we dub $\mathtt {ML}^{\infty }$ and $\mathtt {GML}^{\infty }$, respectively. We then characterise these logics as the bisimulation-invariant fragments of the naturally corresponding predicate logic, viz., the extension of first-order logic with the infinity quantifier. Furthermore, for (...) both $\mathtt {ML}^{\infty }$ and $\mathtt {GML}^{\infty }$ we provide a sound and complete axiomatisation for the set of formulas that are valid in every Kripke frame, we prove a small model property with respect to a widened class of weighted models, and we establish decidability of the satisfiability problem. (shrink)

Quadruple Helix Collaborations (QHCs) is a cooperation model in which industry, government, academia, and the public interact to innovate. This paper analyses the impact of a training intervention to provide specific knowledge, skills, and attitudes to deal with barriers commonly found in the progress of QHCs. We designed, implemented, and evaluated three training programs in Austrian, Colombian, Danish, and Spanish institutions. We analysed trainees’ (n = 66) and trainers’ (n = 9) perceptions to identify the competencies acquired with the intervention (...) and the approach’s limitations. We used online questionnaires (35 trainees; 9 trainers), semi-structured interviews (10 trainees), and a focus group (6 trainers). Trainees answered positively regarding their self-perception about the impact of the course and highlighted the acquisition of inspiration for their practice (score 4.1 out of 5.0) and knowledge (3.7). In contrast, they perceived that a deeper interaction with other participants (2.7) was challenging. After the courses, 74% of respondents indicated that they know more about how QHCs work in practice, and 86% about collaboration or engagement methods. Moreover, participants plan to be more sensitive towards setting common goals (71%) and power imbalances (63%). Trainers’ perceptions align with those expressed by participants, except that they considered that the interaction amongst participants during the course was higher. Qualitative analysis of interviews with participants and the focus group with trainers provides more detail about the strengths and weaknesses of the intervention. Our study shows that the collaborative design and implementation of training impact the participant’s learning competencies, with potential implications in their medium- to long-term practice. (shrink)

The present study focuses on a grammatical category called evidentiality. The primary meaning of evidentiality is concerned with information source. That is, it expresses whether something has been seen, heard or inferred. The aim here is to conduct a conceptual study of evidentiality in which use is made of formal tools. The fundamental intuition is that the distinction between ‘evidence’as ‘proof’and ‘evidentiality’as ‘to do with proof’is a crucial one. Evidentiality is a dynamic notion to be analysed through the use of (...) knowledge by the agents, a knowledge in action, which involves an in-coming state and an out-coming state that is typical of the transmission of information. We propose our own approach in which the dynamics of knowledge in action is grasped in the context of a dynamic epistemic logic. (shrink)

El presente artículo describe un proyecto de innovación educativa de aprendizaje de competencias, realizado en el Curso Propio de Liderazgo de la Universidad San Pablo CEU, transversal a toda su oferta educativa. Se trata de nuevo proyecto basa- do en una docencia híbrida, donde las masterclass más teóricas se han complemen- tado con un aprendizaje basado en retos vinculados a materias de comunicación y sostenibilidad, aplicando la metodología Design Sprint. De esta forma, se consigue formar al alumno en las llamadas (...) habilidades blandas, cada vez más demandadas por el entorno laboral. (shrink)

Frost's article advocates for universal models of reading and critiques recent models that concentrate in what has been described as “cracking the orthographic code.” Although the challenge to develop models that can account for word recognition beyond Indo-European languages is welcomed, we argue that reading models should also be constrained by general principles of visual processing and object recognition.

BackgroundThis article aims to contribute to a better conceptualization of pain and suffering by providing non-essential and non-naturalistic definitions of both phenomena. Contributions of classical evidence-based medicine, the humanistic turn in medicine, as well as the phenomenology and narrative theories of suffering and pain, together with certain conceptions of the person beyond them are critically discussed with such purpose.MethodsA philosophical methodology is used, based on the review of existent literature on the topic and the argumentation in favor of what are (...) found as better definitions of suffering and pain.ResultsPain can be described in neurological terms but cognitive awareness, interpretation, behavioral dispositions, as well as cultural and educational factors have a decisive influence on pain perception. Suffering is proposed to be defined as an unpleasant or even anguishing experience, severely affecting a person at a psychophysical and existential level. Pain and suffering are considered unpleasant. However, the provided definitions neither include the idea that pain and suffering can attack and even destroy the self nor the idea that they can constructively expand the self; both perspectives can b e equally useful for managing pain and suffering, but they are not defining features of the same. Including the existential dimension in the definition of suffering highlights the relevance of suffering in life and its effect on one’s own attachment to the world. An understanding of pain and suffering life experiences is proposed, meaning that they are considered aspects of a person’s life, and the self is the ever-changing sum of these experiences.ConclusionsThe provided definitions will be useful to the identification of pain and suffering, to the discussion of how to relieve them, and to a better understanding of how they are expressed and experienced. They lay the groundwork for further research in all these areas, with the twofold aim of a) avoiding epistemological mistakes and moral injustices, and b) highlighting the limitations of medicine in the treatment of suffering and pain. (shrink)

Diseases of complex origin have a component of quantitative genetics that contributes to their susceptibility and phenotypic variability. However, after several studies, a major part of the genetic component of complex phenotypes has still not been found, a situation known as “missing heritability.” Although there have been many hypotheses put forward to explain the reasons for the missing heritability, its definitive causes remain unknown. Complex diseases are caused by multiple intermediate phenotypes involved in their pathogenesis and, very often, each one (...) of these intermediate phenotypes also has a component of quantitative inheritance. Here we propose that at least part of the missing heritability can be explained by the genetic component of intermediate phenotypes that is not detectable at the level of the main complex trait. At the same time, the identification of the genetic component of intermediate phenotypes provides an opportunity to identify part of the missing heritability of complex diseases. (shrink)

Este artículo analiza la potencia desestabilizadora de la gramática política de la Educación Sexual Integral y su posibilidad de gestar en las escuelas espacios incluyentes en un contexto socio-cultural conservador. Se describe la puesta en acto de la ESI en una provincia del Noroeste Argentino a través de datos relevados en la consulta a estudiantes efectuadas por el Operativo Aprender en 2019 y registros cualitativos de trabajo de campo en escuelas que acogen sujetos de la diversidad sexo-genérica.

The aesthetic tools proposed in this article pursue the intention of articulating and reflecting on dance as a phenomenon and artistic practice both from its generative and reflective ability. For that purpose I establish analogies between the complexities that aesthetic theory and dance share, from the modal interrelationships proposed in Estética modal, which give us the access to think in terms of transitivity, movement and interrelation. Especially in this article, I intend to focus on the intermediate playing field of tension (...) and conflict of the aesthetic experience from the attractive Diamond Theory. (shrink)

¿Cómo objetivar la subjetividad sin caer en subjetivismos inmanentistas ni en objetivismos ajenos a la existencia personal? Desde el realismo filosófico la clave parece encontrarse en la adecuada articulación entre conciencia y subjetividad. Estudiaremos las teorías de la conciencia de Antonio Millán-Puelles y Karol Wojtyła desde la onto-fenomenología para hallar el modo de superar esta aporía. -/- How to objectify subjectivity without falling into either immanent subjectivisms or objectivisms foreign to personal existence? From the perspective of realist philosophy the key (...) seems to be found in an appropriate articulation between consciousness and subjectivity. We are going to study the theories of consciousness in Antonio Millán-Puelles and Karol Wojtyła from onto-phenomenology in order to find the way to overcome this aporia. (shrink)

In the summer of 1995, Santiago Castro-Gómez wrote a convincing text entitled Critique of Latin American Reason, and continued Roberto Salazar-Ramos’ work‒who also took part in The Group of Bogotá, responsible for institutionalizing the project of Latin American Philosophy in Colombia‒in order to show how the creation of “The Latin American” was possible through the operation of a series of discourses. Rather than an a priori, the category of “The Latin American” is defined by Castro-Gómez as the effect of a (...) series of discourses to which a specific cultural identity was provided. Consequently, the author uses the tradition of historicism to rethink the history of ideas, so that, instead of studying the reception of European ideas and measuring how close to that scaffolding was Latin American thought, its study should begin from the philosophical and scientific practices themselves as a “part of the critical exercise in Colombia”. It is precisely within this horizon opened by Castro-Gómez’s writings in which this essay is inserted. (shrink)

An important milestone of 20th Century philosophy was the rise of personalism. After the crimes and atrocities against millions of human beings in two World Wars, especially the Second, some philosophers and other thinkers began to seek arguments showing the value of each human being, to expose and denounce the folly of political structures that violate the inalienable rights of the individual person. -/- Karol Wojtyla appeals to the ancient concept of 'person' to emphasize the particular value of each human (...) being. The person is unique because of their subjectivity by which they possesses an unrepeatable interior world in the history of humanity. Their rational nature grants them a special character among living beings, among which is the transcendence to the infinite. Wojtyla magisterially shows how each human being's personhood is rooted in a conscious and free subjectivity, which is marked also by personal and social responsibility. Wojtyla's original philosophical analysis takes for its starting point the human act, in which consciousness and experience consolidate voluntary choices, which are objectively efficacious. By their acts, the person determines their own personhood. This self-dominion manifests the person and enables them to live together in a community in which one's neighbor can be a companion on the voyage of life. -/- This work provides a clear guide to Karol Wojtyla's principal philosophical work, Person and Act, rigorously analyzing the meaning that the author intended in his exposition. An important feature of the work is that the authors rely on the original Polish text, Osoba i czyn, as well as the best translations into Italian and Spanish, rather than on a flawed and sometimes misleading English edition of the work. -/- Besides the analysis of Wojtyla's masterwork, this volume offers three chapters examining the impact of Wojtyla's anthropology on the relationship between faith and reason. (shrink)

This is a comparative study of the concept of nature in Kant and Fichte’s proposals for perpetual peace. I will argue that Kant and Fichte’s ideas of perpetual peace present two very different ways of dealing with nature: whereas Kant’s proposal consists of administrating the natural unsociable inclinations of human beings, departing from the assumption that the unsociable sociability of men is not only inherent to human nature but also the motor of the historical progress of humanity, Fichte, on the (...) contrary, advocates for a total repression of these inclinations, departing from the postulate that the historical progress of humanity concerns exclusively the spiritual or intelligible dimension of human existence. (shrink)

La Neuroteología surge como una nueva forma de explicar las relaciones entre el ser humano y Dios, las religiones y la espiritualidad en general a partir de la neurología (estudio del sistema nervioso, especialmente del encéfalo). Pero en algunos casos pretende incluso demostrar la existencia o no existencia de Dios. En este trabajo deseo exponer de qué manera algunas formas de Neuroteología manifiestan un rasgo sintomático de la cultura actual donde la ciencia actúa como un saber omnímodo que aspira explicar (...) todos los aspectos de la realidad pasando por alto sus propios límites metodológicos. Algunos investigadores transgreden los principios del método científico-experimental para extrapolarlos a cuestiones filosóficas y teológicas. De esta forma violentan las fronteras epistemológicas de los saberes para convertirse en un único tipo de conocimiento. La ciencia lleva a cabo, cuando menos, un reduccionismo naturalista. -/- Neurotheology appears as a new way to explain the relations between the human being and God, religions, and spirituality in general starting from Neurology (the study of the nervous system, especially the brain). But in certain cases it also pretends to demonstrate the existence or nonexistence of God. In this paper I would like to demonstrate how some forms of Neurotheology offer a symptomatic characteristic of our current culture, where Science acts as an all-embracing knowledge —it aspires to explain the entire aspect of reality— ignoring the limits of its method. Actually, some researchers transgress the principles of the scientific-experimental method and extrapolate to philosophical and theological issues. In this way, they overlap the epistemological limits of the different kinds of knowledge to become one only. Thus, science carries out, to say the least, a naturalist reductionism. (shrink)

El presente trabajo discute el relato de la “normalidad filosófica”, tal como se decantó en algunas versiones posteriores a 1980, con varios elementos de la producción textual de la filosofía en Colombia, entre 1940-1950. A partir de la exposición de distintos enfoques textuales en la escritura de 1940-1950, se dará cuenta del programa o las aspiraciones que algunos escritores depositaron en la filosofía, para poner esto como trasfondo de la revista Ideas y Valores y proponer así una mirada más completa (...) a los textos de los primeros años. (shrink)

El género del evan- gelio de Marcos sigue siendo un problema abierto con varias solu- ciones propuestas, pero está lejos de encontrar un consenso. Este artículo presenta la importancia de tener en cuenta el estudio sobre los géneros literarios realizados por la lingüística en la actualidad, después del estancamiento de los estudios literarios sobre los mis - mos. Estas perspectivas lingüísti- cas sobre el género se aplican al evangelio de Marcos para destacar la importancia de la intención del mismo, la (...) comunidad discursiva, su cosmovisión, etc., como elementos privilegiados para comprender su género. Marcos encuentra en los libros de la LXX su referente más cercano en relación a su dialecto, registro, vocabulario, intención y cosmovisión. (shrink)

Los sótanos del universo plantea la necesidad de cambiar la epistemología del conocimiento apodíctico científico-filosófico basado en la certidumbre por la “epistemología del riesgo”. Asimismo, sugiere un mayor acercamiento entre ciencia y filosofía para superar la actual confusión y estancamiento que afectan a estos saberes. Este artículo analiza ambos temas. -/- Los Sótanos del Universo proposes the necessity of changing the epistemology of apodictic scientific-philosophical knowledge, based on certainty, for the “epistemology of risk”. Furthermore, it suggests a better approach between (...) philosophy and science in order to surpass the confusion and standstill that affect these disciplines today. This paper analyses both matters. (shrink)

La teoría de la intentio hoy conocida como “intencionalidad” había pasado desapercibida en la filosofía moderna y fue recuperada por Brentano, pero sobre todo fue puesta de relieve por Husserl, quien se apoyó en ella como uno de los elementos básicos de su fenomenología. Sin embargo, en esta corriente la intencionalidad perdió su sentido clásico. Así lo pone de manifiesto Jacques Maritain en su gnoseología. ¿Por qué Husserl cambia el sentido del concepto?, ¿cuál es la crítica principal de Maritain a (...) este hecho? Parece pertinente esclarecer ambas visiones a fin de comprender el sentido que ha prevalecido en la Filosofía de la Mente contemporánea y las Neurociencias. Lo que se halla en juego es nuevamente la antigua confrontación entre inmanentismo y realismo gnoseológico: admitir en qué consiste la intencionalidad es el punto de inflexión entre estas posiciones. En este trabajo pongo de manifiesto que la forma de asumir un legítimo realismo es mediante una metafísica del ser que reclama una intencionalidad radicada no solamente en el sujeto cognoscente sino además en su relación con la cosa conocida y no sólo con los meros objetos mentales. -/- El propósito de esta publicación es mostrar el punto de quiebre que se lleva a cabo en la teoría del conocimiento y en la psicología racional con respecto al concepto “intencionalidad” del realismo metafísico. La teoría de la intentio en F. Brentano recoge la idea original de los medievales pero sin ser muy explícito en los términos gnoseológicos ya que su objetivo primario consistió sobre todo en superar el psicologismo de su época. En cambio, esa teoría heredada por Husserl se ve alterada completamente con respecto a su sentido primigenio cuando aplica su método trascendental. Esto se puede apreciar en varias partes de su obra "Ideas relativas a una fenomenología pura y una filosofía fenomenológica" (1913). (shrink)

Hannah Arendt connects the end of Modernity with a historical specific event: the ascent of Totalitarianisms. According to Arendt, that event would have supposed a cut in History and Tradition, a gap between a suddenly foreign past and an unforseeable future. In this article I restate Arendt’s solutions to the problem of how can be reminded and told what, after the break in History and Philosophical Tradition, it is not possible to understand trought the traditional categories of significance. This solution (...) consist on: a phenomenological philosophical method, a «History of events» instead of a History of process and a defense of free thinking, capable of facing the reality his own resources.  . (shrink)

In recent years, the concept of reifcation has sparked new interest among scholars, particularly in the domain of contemporary critical theory. Authors discussing reifcation usually mention Heidegger, but this is often limited to his major work, Being and Time. In this paper, though, I focus on machination, a fundamental concept that appears in Heidegger’s posthumous texts of the 1930s. Using this concept, Heidegger tries to elucidate how modernity has emptied the meaning of Being of its efective reality. I frst show (...) how the notion of Machenschaft ofers a new perspective on reifcation and how it opens up a historical-metaphysical approach to Heidegger’s other key concepts. To complete this analysis, the second section uses Adorno’s critique in Negative Dialectics to interpret the concept of Machenschaft-reifcation, clarifying its limits and the fruitful possibilities it ofers. (shrink)

IntroductionCerebral visual impairment results from damage to cerebral visual processing structures. It is the most common cause of pediatric visual impairment in developed countries and rising in prevalence in developing nations. There is currently limited understanding on how neurologic, developmental, and ophthalmic factors predict outcome for pediatric CVI.MethodA retrospective manual chart review of pediatric CVI patients seen at the tertiary pediatric hospital neurology and neuro-ophthalmology service between 2010 and 2019 was conducted. Patients were stratified into severity groups, and followed over (...) time to identify outcome predictors. Collected baseline characteristics included perinatal, genetic, developmental, and neurologic history, along with neuroimaging and fundoscopic findings on examination. Longitudinal data collected included age, seizure control, and type of therapy received. Linear mixed-effect models were used for longitudinal CVI grade outcome analysis.ResultsA total of 249 individuals spanning 779 patient visits were identified. Mean age at diagnosis was 18.8 ± 16.8 months. About 64.3% were born at term age. Perinatal history revealed hypoxic ischemic encephalopathy in 16.5%, intraventricular hemorrhage in 11.6%, and seizures in 21.7%. At presentation, 60.3% had a diagnosis of cerebral palsy and 84.7% had developmental delay. Among all subjects, 78.6% had epilepsy; 33.8% had an epileptic encephalopathy, with spasms/hypsarrhythmia being most common. Abnormal neuroimaging was present in 93.8%. Genetic anomalies were present in 26.9%. Baseline visual examination revealed no blink-to-light in 24.5%; only BTL in 34.5%, fixation/tracking in 26.5%, and optokinetic drum follow in 14.4%. Longitudinal data analysis showed that perinatal history of HIE, a positive epilepsy history, using multiple epilepsy medications, cerebral palsy, and abnormal fundoscopic findings were all negatively associated with CVI grade change over time. After controlling for significant confounders, receiving any type of therapy [early childhood intervention, physical and occupational therapy, refractive error correction or glasses] was significantly associated with longitudinal improvement in CVI grade compared to patients who did not receive any therapy, with glasses yielding the largest benefit.ConclusionThis study offers extensive insights into neurologic, developmental and ophthalmologic features in patients with moderate to severe CVI. In concordance with previous findings, aspects of perinatal history and epilepsy/seizure control may help inform severity and prognosis in the general neurology or ophthalmology clinic. Conversely, these aspects, as well as genetic and specific epilepsy traits may alert vision health care providers in the clinic to pursue visual evaluation in at-risk individuals. Longitudinal follow-up of CVI patients showed that interventional therapies demonstrated vision function improvement greater than no therapy and maturational development. (shrink)

Integrated approaches in the ethical decision-making (EDM) and practically wise decision-making literature are emerging as alternative perspectives to management theories that conceptualize decision-making in a rationalist and value-free manner. However, more dialogue between both perspectives and qualitative research that applies them is required. In addition, there is a need for empirical analysis on business engagement in the face of grand challenges in developing countries. This paper proposes an integrated practically wise EDM framework to study how Colombian councilors who, in 2013, (...) voted for or against the merger between the Colombian state-owned company UNE and the Swedish multinational Millicom interpret this decision and its public impact. Qualitative semi-structured interviews were conducted with a voluntary sample of 18 of 21 councilors. Supporters of the UNE-Millicom merger expressed open-mindedness, seeing the merger as a means to achieve justice. On the contrary, the merger’s opponents expressed circumspection, doubting that Millicom’s intentions really leaned toward justice. We conclude that practical wisdom—embodied by both supporters and detractors—fosters an understanding of EDM beyond what leaders should not do. It also includes a democratic and balanced deliberation on what leaders think they should do to promote the common good. (shrink)

Journal of Political Philosophy, EarlyView.