The Reign of Quantity gives a concise but comprehensive view of the present state of affairs in the world, as it appears from the point of view of the 'ancient wisdom', formerly common both to the East and to the West, but now almost entirely lost sight of. The author indicates with his fabled clarity and directness the precise nature of the modern deviation, and devotes special attention to the development of modern philosophy and science, and to the part played (...) by them, with their accompanying notions of progress and evolution, in the formation of the industrial and democratic society which we now regard as 'normal'. Guénon sees history as a descent from Form (or Quality) toward Matter (or Quantity); but after the Reign of Quantity-modern materialism and the 'rise of the masses'-Guénon predicts a reign of 'inverted quality' just before the end of the age: the triumph of the 'counter-initiation', the kingdom of Antichrist. This text is considered the magnum opus among Guénon's texts of civilizational criticism, as is Symbols of Sacred Science among his studies on symbols and cosmology, and Man and His Becoming according to the Vedanta among his more purely metaphysical works. (shrink)

Description: Contents: Preface 1. General Remarks on the Vedanta 2. Fundamental Distinction Between The Self and the Ego 3. The Vital Centre of the Human Being, Seat of Brahma 4. Purusha and Prakriti 5. Purusha Unaffected by Individual Modifications 6. The Degrees of Individual Manifestation 7. Buddhi or the Higher Intellect 8. Manas or the Inward Sense : The Ten External Faculties of Sensation and Action 9. The Envelopes of the Self ; The Five Vayus or Vital Functions 10. The (...) Essential Unity and Identity of the Self in all the States of the Being 11. The Different Conditions of Atma in the Human Being 12. The Waking State or the Condition of Vaishwanara 13. The Dream State or the Condition of Taijasa 14. The State of Deep Sleep or the Condition of Prajna 15. The Unconditioned State of Atma 16. The Symbolical Representation of Atma and its Conditions by the Sacred Monosyllable Om 17. The Posthumous Evolution of the Human Being 18. The Reabsorption of the Individual Faculties 19. Differences in the Posthumous Conditions According to the Degrees of Knowledge 20. The Coronal Artery and the Solar Ray 21. The Divine Journey of the Being on the Path of Liberation 22. Final Deliverance 23. Videha-mukti and Jivana-mukti 24. The Spiritual State of the Yogi : The Supreme Identity. (shrink)

Written for non-experts, this volume introduces the mechanisms that underlie reticulate evolution. Chapters are either accompanied with glossaries that explain new terminology or timelines that position pioneering scholars and their major discoveries in their historical contexts. The contributing authors outline the history and original context of discovery of symbiosis, symbiogenesis, lateral gene transfer, hybridization or divergence with gene flow, and infectious heredity. By applying key insights from the areas of molecular (phylo)genetics, microbiology, virology, ecology, systematics, immunology, epidemiology and computational (...) science, they demonstrate how reticulate evolution impacts successful survival, fitness and speciation. Reticulate evolution brings forth a challenge to the standard Neo-Darwinian framework, which defines life as the outcome of bifurcation and ramification patterns brought forth by the vertical mechanism of natural selection. Reticulate evolution puts forward a pattern in the tree of life that is characterized by horizontal mergings and lineage crossings induced by symbiosis, symbiogenesis, lateral gene transfer, hybridization or divergence with gene flow, and infective heredity, making the “tree of life” look more like a “web of life.” On an epistemological level, the various means by which hereditary material can be transferred horizontally challenges our classic notions of units and levels of evolution, fitness, modes of transmission, linearity, communities, and biological individuality. The case studies presented examine topics including the origin of the eukaryotic cell and its organelles through symbiogenesis; the origin of algae through primary and secondary symbiosis and dinoflagellates through tertiary symbiosis; the superorganism and holobiont as units of evolution; how endosymbiosis induces speciation in multicellular life forms; transferrable and non-transferrable plasmids and how they symbiotically interact with their host; the means by which pro- and eukaryotic organisms transfer genes laterally (bacterial transformation, transduction and conjugation as well as transposons and other mobile genetic elements); hybridization and divergence with gene flow in sexually-reproducing individuals; current (human) microbiome and viriome studies that impact our knowledge concerning the evolution of organismal health and acquired immunity; and how symbiosis and symbiogenesis can be modelled in computational evolution. (shrink)

A theorem is derived that enables a systematic enumeration of all the linear superoperators ℒ (associated with a two-level quantum system) that generate, via the law of motion ℒρ= $\dot \rho$ , mappings ρ(0) → ρ(t) restricted to the domain of statistical operators. Such dynamical evolutions include the usual Hamiltonian motion as a special case, but they also encompass more general motions, which are noncyclic and feature a destination state ρ(t → ∞) that is in some cases independent of (...) ρ(0). (shrink)

In a series of papers, Forber and Smead :151–166, 2014, Biol Philos 30:405–421, 2015) and Smead and Forber :698–707, 2013) make a valuable contribution to the study of cooperation in finite populations by analyzing an understudied model: the prisoner’s delight. It always pays to cooperate in the one-shot prisoner’s delight, so this model presents a best-case scenario for the evolution of cooperation. Yet, what Forber and Smead find is highly counterintuitive. In finite populations playing the prisoner’s delight, increasing the (...) benefit of cooperation causes selection to favor defection. Here, I extend their model by considering the effects of non-linear payoffs. In particular, I show that interesting subtleties arise when payoffs are synergistic. Indeed, analysis reveals that increasing the benefit of cooperation does not always favor the spread of defection if payoffs are synergistic. I conclude by drawing some general considerations about robustness analysis in evolutionary models. (shrink)

Experimental tests about cross-cultural differentiation of cognitive style conclude that East Asian and Western cognition differ. Tendencies described as East Asian include holism, non-linearity, expectation of change, relationalism, field dependence, causal pluralism, dialecticism, and a tolerance of contradiction. Cross-cultural psychologists generally refrain from discussing the intellectual history or cultural evolution of these differences, preferring to explain results on cognitive scales in terms of results on social scales assessed using present-day participants. The present article attempts to partially close this explanatory (...) gap through detailed discussion of tendencies of East Asian cognitive style as represented in what is probably the most influential book in the history of East Asia, The Book of Changes. This study purports to show that the content of the Yijing 易經 and its commentaries is best described in terms of the cognitive tendencies just mentioned, that reading the Yijing activated those cognitive tendencies, and that the Yijing attained prodigious influence on subsequent Chinese and East Asian cultures through four known mechanisms of cultural transmission. Informed by this case study, researchers of cross-cultural cognition may be positioned to develop a richer appreciation of the cultural representation and evolution of East Asian cognitive style in historical context. (shrink)

Cross-linguistic evidence from widespread modes of language variation and change demonstrate that language evolution proceeds (at least in part, perhaps in whole) by breaking and renewing symmetrical patterns. Since this activity is identified with semiosis (Nöth 1994, 1998), these patterns-in-process establish further grounds for insisting that the science of language be more adequately situated within semiotic understanding as “an ideoscopic science and sub-discipline under the general doctrine of signs” (Deely 2012: 334). After summarizing the theoretical context of my thesis, (...) including relationships between analogy, symmetry, and linguistic diagrammatization, I present supporting comparative data in successive stages of complexity, ranging from simple reversals of linguistic diagrams through time to the emergence of more involved linguistic mirror patterns, to the emergence of intertwining diagrams and linguistic fractal symmetries. I then point back to the embodied and psychological sources of these patterns in the primary modeling system of the human Umwelt. The essay ends with gestures toward further unexplored sources of evidence and a summary proposal for understanding language evolution as non-linear process, qua semiosis. (shrink)

The meaning of the wave function and its evolution are investigated. First, we argue that the wave function in quantum mechanics is a description of random discontinuous motion of particles, and the modulus square of the wave function gives the probability density of the particles being in certain locations in space. Next, we show that the linear non-relativistic evolution of the wave function of an isolated system obeys the free Schrödinger equation due to the requirements of spacetime (...) translation invariance and relativistic invariance. Thirdly, we argue that the random discontinuous motion of particles may lead to a stochastic, nonlinear collapse evolution of the wave function. A discrete model of energy-conserved wavefunction collapse is proposed and shown consistent with existing experiments and our macroscopic experience. Besides, we also give a critical analysis of the de Broglie-Bohm theory, the many-worlds interpretation and other dynamical collapse theories, and briefly discuss the issues of unifying quantum mechanics and relativity. (shrink)

Humankind is currently confronted with a critical challenge that determines its very existence, not only on an individual, racial, or national level but as a whole species: the fight against climate change and environmental degradation. To win this battle, humanity needs innovations and non-linear thinking. Nature has long been a substantial information source for unthinkable discoveries that save human lives. The paper suggests that by understanding the nature, emergence, and mechanism of serendipity, the survival skill of humans, humanity can (...) capitalize on it to learn from nature and generate nature-based innovations that can address the climate and environmental degradation crises. In the era of Artificial Intelligence (AI) proliferation, AI will be a vital tool providing navigational and useful information to leverage the power of serendipity in climate and sustainability science. However, an eco-surplus culture that incorporates core values pertaining to nature and sees environmental sustainability as the conscience of the times needs to be built to direct and control the immense power of AI-leveraged serendipity. Insights applied in this paper are drawn from the book titled “A New Theory of Serendipity: Nature, Emergence and Mechanism”. (shrink)

Humankind is currently confronted with a critical challenge that determines its very existence, not only on an individual, racial, or national level but as a whole species: the fight against climate change and environmental degradation. To win this battle, humanity needs innovations and non-linear thinking. Nature has long been a substantial information source for unthinkable discoveries that save human lives. The paper suggests that by understanding the nature, emergence, and mechanism of serendipity, the survival skill of humans, humanity can (...) capitalize on it to learn from nature and generate nature-based innovations that can address the climate and environmental degradation crises. In the era of Artificial Intelligence (AI) proliferation, AI will be a vital tool providing navigational and useful information to leverage the power of serendipity in climate and sustainability science. However, an eco-surplus culture that incorporates core values pertaining to nature and sees environmental sustainability as the conscience of the times needs to be built to direct and control the immense power of AI-leveraged serendipity. Insights applied in this paper are drawn from the book titled “A New Theory of Serendipity: Nature, Emergence and Mechanism”. (shrink)

We have demonstrated, using the Cantor dust method, that the statistical distribution of appearance and disappearance of rodents species (Arvicolid rodent radiation in Europe) follows power laws strengthening the evidence for a fractal structure set. Self-similar laws have been used as model for the description of a huge number of biological systems. With Nottale we have shown that log-periodic behaviors of acceleration or deceleration can be applied to branching macroevolution, to the time sequences of major evolutionary leaps (global life tree, (...) sauropod and theropod dinosaurs postural structures, North American fossil equids, rodents, primates and echinoderms clades and human ontogeny). The Scale-Relativity Theory has others biological applications from linear with fractal behavior to non-linear and from classical mechanics to quantum mechanics. (shrink)

This article investigates the relationship between political revolutions and the evolution of politics. It discusses the circularity within the concept of revolution through Jacques Derrida’s theory of sovereignty as particularly per Rogues – Two Essays on Reason and The Beast and the Sovereign. Derrida’s notions of wheel and ipseity display ontological prerogatives and evolutionary limits of political revolutions possibly coinciding with reversals hard to turn into linear evolutions, excluding rather than reaffirming circularity. Political revolutions show such incapacity to (...) become evolutionary for politics when lacking ontological substance and resting upon formal contingencies such as new techniques. An ‘alturnative’ notion of sovereignty is proposed as a heuristic criterion to gauge political events’ ‘revolutionary’ quality. This undermines the (r)evolutionary nature of political turns, like those associated with the contemporary digitalisation of politics. The Italian Five Stars Movement’s parable is a case in point of digital political turns whose effect is non-evolutionary for politics. (shrink)

This article investigates the relationship between political revolutions and the evolution of politics. It discusses the circularity within the concept of revolution through Jacques Derrida’s theory of sovereignty as particularly per Rogues – Two Essays on Reason and The Beast and the Sovereign. Derrida’s notions of wheel and ipseity display ontological prerogatives and evolutionary limits of political revolutions possibly coinciding with reversals hard to turn into linear evolutions, excluding rather than reaffirming circularity. Political revolutions show such incapacity to (...) become evolutionary for politics when lacking ontological substance and resting upon formal contingencies such as new techniques. An ‘alturnative’ notion of sovereignty is proposed as a heuristic criterion to gauge political events’ ‘revolutionary’ quality. This undermines the (r)evolutionary nature of political turns, like those associated with the contemporary digitalisation of politics. The Italian Five Stars Movement’s parable is a case in point of digital political turns whose effect is non-evolutionary for politics. (shrink)

This article investigates the relationship between political revolutions and the evolution of politics. It discusses the circularity within the concept of revolution through Jacques Derrida’s theory of sovereignty as particularly per Rogues – Two Essays on Reason and The Beast and the Sovereign. Derrida’s notions of wheel and ipseity display ontological prerogatives and evolutionary limits of political revolutions possibly coinciding with reversals hard to turn into linear evolutions, excluding rather than reaffirming circularity. Political revolutions show such incapacity to (...) become evolutionary for politics when lacking ontological substance and resting upon formal contingencies such as new techniques. An ‘alturnative’ notion of sovereignty is proposed as a heuristic criterion to gauge political events’ ‘revolutionary’ quality. This undermines the (r)evolutionary nature of political turns, like those associated with the contemporary digitalisation of politics. The Italian Five Stars Movement’s parable is a case in point of digital political turns whose effect is non-evolutionary for politics. (shrink)

This article investigates the relationship between political revolutions and the evolution of politics. It discusses the circularity within the concept of revolution through Jacques Derrida’s theory of sovereignty as particularly per Rogues – Two Essays on Reason and The Beast and the Sovereign. Derrida’s notions of wheel and ipseity display ontological prerogatives and evolutionary limits of political revolutions possibly coinciding with reversals hard to turn into linear evolutions, excluding rather than reaffirming circularity. Political revolutions show such incapacity to (...) become evolutionary for politics when lacking ontological substance and resting upon formal contingencies such as new techniques. An ‘alturnative’ notion of sovereignty is proposed as a heuristic criterion to gauge political events’ ‘revolutionary’ quality. This undermines the (r)evolutionary nature of political turns, like those associated with the contemporary digitalisation of politics. The Italian Five Stars Movement’s parable is a case in point of digital political turns whose effect is non-evolutionary for politics. (shrink)

Early 20th century philosopher Henri Bergson posited an initial push that propelled the diversity of life forward into a varied, novel future: The élan vital, a necessary force or impulse that animated life’s progress and development. His idea had largely been abandoned by mid-century. Even so, much of the conceptual and explanatory work this impulse targeted is yet in want of an explanation. In particular, Bergson’s derelict ideas on evolution addressed three areas that have once again become relevant in (...) the effort to unite evolutionary genetics, biological development, and ecological context : the purposeful nature of individual organisms and their parts; the integrative, holistic, non-linear emergent dynamics seen in evolutionary processes; and how genuine novelty emerges into the universe :422, 2016; Simondon et al. in On the mode of existence of technical objects. Univocal series, Univocal Publishing LLC, Minneapolis, 2017; Bang, in: Winther-Lindqvist, Bang, Valsiner Nothingness: philosophical insights into psychology, Transaction Publishers, Somerset, 2016; Moreno and Mossio in Biological autonomy: a philosophical and theoretical enquiry. History, philosophy and theory of the life sciences, Springer, Dordrecht, 2015). In this paper I argue that Bergson’s ideas may yet be relevant to these questions, and his work warrants a reexamination in light of current problems in evolutionary biology. This is not a call to ‘return’ to Bergson, nevertheless his notions about complexity suggest ways of looking at current biological problems in ways that offer a heuristic insight worth entertaining. Bergson’s Nobel Prize-winning book, Creative Evolution, provided a strikingly prescient early 20th century framework for understanding how Darwinian evolution acts as an engine for generating new forms, University Press of America, Lanham, Bergson 1911). (shrink)

A categorical, higher dimensional algebra and generalized topos framework for Łukasiewicz–Moisil Algebraic–Logic models of non-linear dynamics in complex functional genomes and cell interactomes is proposed. Łukasiewicz–Moisil Algebraic–Logic models of neural, genetic and neoplastic cell networks, as well as signaling pathways in cells are formulated in terms of non-linear dynamic systems with n-state components that allow for the generalization of previous logical models of both genetic activities and neural networks. An algebraic formulation of variable ‘next-state functions’ is extended to (...) a Łukasiewicz–Moisil Topos with an n-valued Łukasiewicz–Moisil Algebraic Logic subobject classifier description that represents non-random and non-linear network activities as well as their transformations in developmental processes and carcinogenesis. The unification of the theories of organismic sets, molecular sets and Robert Rosen’s (M,R)-systems is also considered here in terms of natural transformations of organismal structures which generate higher dimensional algebras based on consistent axioms, thus avoiding well known logical paradoxes occurring with sets. Quantum bionetworks, such as quantum neural nets and quantum genetic networks, are also discussed and their underlying, non-commutative quantum logics are considered in the context of an emerging Quantum Relational Biology. (shrink)

A categorical, higher dimensional algebra and generalized topos framework for Łukasiewicz–Moisil Algebraic–Logic models of non-linear dynamics in complex functional genomes and cell interactomes is proposed. Łukasiewicz–Moisil Algebraic–Logic models of neural, genetic and neoplastic cell networks, as well as signaling pathways in cells are formulated in terms of non-linear dynamic systems with n-state components that allow for the generalization of previous logical models of both genetic activities and neural networks. An algebraic formulation of variable ‘next-state functions’ is extended to (...) a Łukasiewicz–Moisil Topos with an n-valued Łukasiewicz–Moisil Algebraic Logic subobject classifier description that represents non-random and non-linear network activities as well as their transformations in developmental processes and carcinogenesis. The unification of the theories of organismic sets, molecular sets and Robert Rosen’s (M,R)-systems is also considered here in terms of natural transformations of organismal structures which generate higher dimensional algebras based on consistent axioms, thus avoiding well known logical paradoxes occurring with sets. Quantum bionetworks, such as quantum neural nets and quantum genetic networks, are also discussed and their underlying, non-commutative quantum logics are considered in the context of an emerging Quantum Relational Biology. (shrink)

We present a formal derivation of the Mino–Sasaki–Tanaka–Quinn–Wald (MSTQW) equation describing the self-force on a (semi-) classical relativistic point mass moving under the influence of quantized linear metric perturbations on a curved background space–time. The curvature of the space–time implies that the dynamics of the particle and the field is history-dependent and as such requires a non-equilibrium formalism to ensure the consistent evolution of both particle and field, viz., the worldline influence functional and the closed- time-path (CTP) coarse-grained (...) effective action. In the spirit of effective field theory, we regularize the formally divergent self-force by smearing the local part of the retarded Green’s function and employing a quasi-local expansion. We derive the MSTQW–Langevin equations describing the perturbations of the particle’s worldline about its semi-classical trajectory resulting from interactions with the quantum fluctuations of the linear metric perturbations. Finally, we demonstrate that the quantum fluctuations of the field could, in principle, leave imprints on gravitational waveforms expected to be observed by gravitational interferometers, thereby encoding information about tree-level perturbative quantum gravity. (shrink)

We present a technique for the analysis of pattern formation by a class of models for the formation of ocular dominance stripes in the striate cortex of some mammals. The method, which employs the adiabatic approximation to derive a set of ordinary differential equations for patterning modes, has been successfully applied to reaction-diffusion models for striped patterns [1]. Models of ocular dominance stripes have been studied [2,3] by computation, or by linearization of the model equations. These techniques do not provide (...) a rationale for the origin of the stripes. We show here that stripe formation is a non-linear property of the models. Our analysis indicates that stripe selection is closely linked to a property in the dynamics of the models which arises from a symmetry between ipsilateral and contralateral synapses to the visual cortex of a given hemisphere. (shrink)

The aim of this work is to consider individual symptoms and areas of alienation in the history of mankind and in the modern information society, and the disclosure of its logic and patterns. Methodologically, the study is based on the historical, information and cybernetic approaches. The paper points to a positive feedback between the amount of knowledge in alienated form and figures of society, the development of its comprehensive intelligence. New forms of exclusion, which exist in the form of artificial (...) intelligence, robotics, and global computer networks, are analysed. The findings suggest a communicative model of the interaction of mankind with man-made external memory, which describes a non-linear process of communicating to it all human knowledge and intellectual abilities. It is emphasized that the contradiction between man and the material world created by him is the main contradiction of modernity. (shrink)

Introduction The article is focused on theoretical and methodological analysis of a number of social dynamics models that appeared on the basis of non-classical science. They are “challenge — response”, self-organization, a cycle of phase transitions “birth — life — death”, and “zone model”. The author reveals heuristic potential of each model, its strengths and weaknesses in the methodological aspect. The aim of the study is to consider the models of social dynamics that appeared on the basis of non-classical science (...) in social cognition, identify their methodological foundations; compare these theoretical constructs with each other, and to improve these structures in theoretical and methodological aspects. Methods The following general scientific methods were used in the study: modeling, structural-functional, systemic and comparative analysis. The scientific novelty of the study. The author traces evolution of how the models under consideration have been forming in the framework of social cognition, and points out the epistemological foundations of their occurrence. In the “challenge-response” model, the author identifies its basic ideas and classifies the sources that generate historical “challenges” and the entities that form “answers” to them. The author specifies that the model of self-organization appeared long before the 20th century, but only thanks to the systematic approach and synergetics it acquires the necessary theoretical level. The author also points out positive aspects and limitations of the self-organization model in relation to social cognition. The author specifies the full structure of the “zone model” in social cognition, which includes the following elements: the center, the middle part, the intermediate space, and the periphery. Modifications of this model are shown in the framework of the world-system approach and other social theories. Results. The study demonstrates that in relation to each model, empirical material was first accumulated, and only then it was theoretically generalized on the basis of non-classical science. It is shown that the main merit of the world-system analysis is creating a “zone” model of social dynamics. The author recognizes that the zone model to the maximum extent includes other theoretical constructions: “challenge - answer”, self-organization, the cycle of phase transitions “birth - life - death”. It is assumed that in the future, theoretical approaches in the humanities are more likely to include new methodological tools. Conclusions. The author reveals continuity of intellectual instruments among various non-classical models of social dynamics, shows separate stages of the models evolution. It is stated that in the framework of the non-classical methodology of social cognition, there is a place for the approaches generated by classical science (for example, the assumption of linearity as a way of developing society). (shrink)

We develop an extension of the familiar linear mixed logit model to allow for the direct estimation of parametric non-linear functions defined over structural parameters. Classic applications include the estimation of coefficients of utility functions to characterize risk attitudes and discounting functions to characterize impatience. There are several unexpected benefits of this extension, apart from the ability to directly estimate structural parameters of theoretical interest.

The rise of the sitar from a limited accompaniment instrument used in the regional courts of Northern India to an internationally recognized cultural icon underscores its importance both as an instrument and a cultural symbol—the sitar mirrors India’s social complexity. This story encapsulates the social, political and economic trauma resulting from the dismantling of Mughal empire to the partition of Pakistan, reflecting contesting social narratives and Hindu/Muslim cultural heritages through the distinctive musical styles modern India. A musical instrument and material (...) object of contested origins, the sitar extends from wood, gourd, wire, and ivory into complex social and cultural networks. I argue that the sitar, as object, cannot be reduced to either an empirical or phenomenological entity; it is a space of potentiality, the actualization of a virtual object. I examine the sitar as both byproduct and narrative, demonstrating how it defies attempts to limit its constantly rupturing borders with imposed cognitive frames, and how materiality and philosophical systems can inform ethnographic practice. (shrink)

In this work we present a dynamical approach to quantum logics. By changing the standard formalism of quantum mechanics to allow non-Hermitian operators as generators of time evolution, we address the question of how can logics evolve in time. In this way, we describe formally how a non-Boolean algebra may become a Boolean one under certain conditions. We present some simple models which illustrate this transition and develop a new quantum logical formalism based in complex spectral resolutions, a notion (...) that we introduce in order to cope with the temporal aspect of the logical structure of quantum theory. (shrink)

In 1997, the Japanese Diet revised the Bank of Japan law thereby granting the central bank greater independence in monetary policy making. The revision was an attempt by Japan's political class to weaken the authority of the powerful Ministry of Finance over the central bank and augment its own influence. The Bank of Japan, however, gained more autonomy than politicians ever intended, leading to frequent confrontations between the government and the central bank over monetary policy. This paper explores the new (...) strategic relationship that emerged between the Bank of Japan and government and the nature of monetary policy implemented in the post-reform period. We demonstrate that several factors contributed to the Bank's unexpected ability to enhance its independence: the astute leadership of the first post-reform governor Hayami Masaru; the Bank's ability to turn politicization of monetary policy to its advantage; and its pursuit of a strategy achieved by augmenting its own research capacity. On a theoretical level, our findings show that the passage of a new legal framework only marks the completion of one stage of institutional change and the start of the next; post-enactment politics have as much importance as pre-enactment politics in shaping outcomes. In the post-enactment phase, various factors, including the state of the economy and informal institutions or processes, matter greatly and may shift the direction of institutional change away from the intended path. (shrink)

BackgroundThe literature shows the negative psychological impact of the coronavirus disease 2019 outbreak on frontline healthcare workers. However, few are known about the mental health of physicians and nurses working in general hospitals during the outbreak, caring for patients with COVID-19 or not.ObjectivesThis survey assessed differences in mental health in physicians and nurses working in COVID-19 or non-COVID-19 medical care units.DesignA cross-sectional mixed-mode survey was used to assess burnout, insomnia, depression, anxiety, and stress.SettingA total of 1,244 physicians and nurses from (...) five general hospitals in Belgium, working in COVID-19 care units, non-COVID-19 care units, or both were informed of the study.ParticipantsSix hundred forty-seven healthcare workers participated in the survey.MeasurementsValidated instruments were used to assess the outcomes: the PFI, the ISI, and the DASS-21.ResultsResults showed high prevalence of burnout, insomnia, depression, and anxiety among participants. After adjusting for confounders, multivariate analysis of variance showed no differences between CCU, NCCU, and CCU + NCCU workers. Univariate general linear models showed higher level of burnout, insomnia, and anxiety among nurses in comparison to physicians. Being a nurse, young, isolated, with an increased workload were risk factors for worse mental health outcomes.LimitationsThe mental health of the tested sample, before the outbreak, is unknown. Moreover, this cross-sectional design provides no information on the evolution of the mental health outcomes over time.ConclusionDirectly caring for patients with COVID-19 is not associated with worse mental health outcomes among healthcare workers in general hospitals. High prevalence of burnout, insomnia, depression, and anxiety among physicians and nurses requires special attention, and specific interventions need to be implemented.Protocol RegistrationClinicalTrials.gov, identifier NCT04344145. (shrink)

Genome complexity is correlated with biological complexity. A recent paper by Michael Lynch proposes that evolution of complex genomic architecture was driven primarily by non‐adaptive stochastic forces, rather than by adaptive evolution.1 A general negative relationship between selection efficiency and genome complexity provides a strong support for this hypothesis. The broad capacity of this theory is both its appeal and source for criticism. BioEssays 28: 979–982, 2006. © 2006 Wiley Periodicals, Inc.

Most of the descriptions of interval time structures in the first order predicate calculus are based on linear time. However, in the case of intervals, abandoning the condition oflinearity (e.g.LIN in van Benthem's systems) is not sufficient. In this paper, some properties of non-linear time structures are discussed. The most important one is the characterization of location of intervals in a fork of branches. This is connected with the fact that an interval can contain non-collinear subintervals. As a (...) result of non-linearity, some basic properties of interval structures must be formulated in a weaker form. Moreover, time must be filled by intervals to indicate that time cannot pass without events occurring in it. Finally, it is shown that when intervals cannot contain non-collinear subintervals, most of the conditions described in the paper are satisfied. (shrink)