In addition to monocentric eukaryotes, which have a single localized centromere on each chromosome, there are holocentric species, with extended repeat‐based or repeat‐less centromeres distributed over the entire chromosome length. At least two types of repeat‐based holocentromeres exist, one composed of many small repeat‐based centromere units (small unit‐type), and another one characterized by a few large centromere units (large unit‐type). We hypothesize that the transposable element‐mediated dispersal of hundreds of short satellite arrays formed the small centromere unit‐type holocentromere in Rhynchospora (...) pubera. The large centromere unit‐type of the plant Chionographis japonica is likely a product of simultaneous DNA double‐strand breaks (DSBs), which initiated the de novo formation of repeat‐based holocentromeres via insertion of satellite DNA, derived from extra‐chromosomal circular DNAs (eccDNAs). The number of initial DSBs along the chromosomes must be higher than the number of centromere units since only a portion of the breaks will have incorporated eccDNA at an appropriate position to serve as future centromere unit sites. Subsequently, preferential incorporation of the centromeric histone H3 variant at these positions is assumed. The identification of repeat‐based holocentromeres across lineages will unveil the centromere plasticity and elucidate the mechanisms underlying the diverse formation of holocentromeres. (shrink)

Loneliness and solitude have similar attributes to individuals, but there is a critical variance between the two regarding the impact on the individual. Loneliness is an unpleasant feeling in a broad sense, while according to some philosophers, solitude is regarded as a joyful necessity when one establishes a deep relationship with the outside world. This article aims to develop a sensible account of the difference between solitude and loneliness by looking at some insightful philosophical viewpoints. Importantly, this article aims to (...) explain the dimensions in which solitude is a positive phenomenon. I will analyze the role of solitude in eliminating loneliness from two aspects: self-consciousness and self-knowledge construction. (shrink)

Beyond protein synthesis and autophagy, emerging evidence has implicated mTORC1 in regulating protein folding and proteasomal degradation as well, highlighting its prominent role in cellular proteome homeostasis or proteostasis. In addition to growth signals, mTORC1 senses and responds to a wide array of stresses, including energetic/metabolic stress, genotoxic stress, oxidative stress, osmotic stress, ER stress, proteotoxic stress, and psychological stress. Whereas growth signals unanimously stimulate mTORC1, stresses exert complex impacts on mTORC1, most of which are repressive. mTORC1 suppression, as a (...) generic adaptive strategy, empowers cell survival under various stressful conditions. In this essay, we provide an overview of the emerging role of mTORC1 in proteostasis, the distinct molecular mechanisms through which mTORC1 reacts to diverse stresses, and the schemes exploited by cancer cells to circumvent stress‐induced mTORC1 suppression. Hence, acting as a stress sensor, mTORC1 intimately couples stresses to cellular proteostasis. (shrink)

In previous decades, the well-being of teachers has been at the center of the attention of researchers in several practical investigations on various subjects such as language learning. The objective of this review is to clarify this construct and add new information on the predominance of the well-being of teachers and organize factors impacting it. Nevertheless, among factors influencing the levels of well-being, the focus of this review is on two constructs, namely, optimism “as a new concept in positive psychology,” (...) societal theory, and collective school assets in education, and efficacy of teachers as an individual source in teachers. This review tries to focus on the eminent role of teacher efficacy and optimism in the process of education and also clarify their consequences on the well-being of teachers. In a nutshell, this review can provide implications for language teaching participants in the academic context. (shrink)

Concerns with improper collection and usage of personal information by businesses or governments have been seen as critical to the success of the emerging electronic commerce. In this regard, computer professionals have the oversight responsibility for information privacy because they have the most extensive knowledge of their organization's systems and programs, as well as an intimate understanding of the data. Thus, the competence of these professionals in ensuring sound practice of information privacy is of great importance to both researchers and (...) practitioners. This research addresses the question of whether male computer professionals differ from their female counterparts in their self-regulatory efficacy to protect personal information privacy. A total of 103 male and 65 female subjects surveyed in Taiwan responded to a 10-item questionnaire that includes three measures: protection, non-distribution, and non-acquisition. The findings show significant gender differences exist in the subjects' overall self-regulatory efficacy for information privacy, and, in particular, that female subjects in this study exhibited a higher level of self-regulatory efficacy than males for the protection and non-acquisition of personal privacy information. The identification of the factorial structure of the self-regulatory efficacy concerning information privacy may contribute to future research directed to examining the links between privacy efficacy and psychological variables, such as ethical attitude, ethical intention, and self-esteem. Studies can also be extended to investigate how different cultural practices of morality and computer use in men and women may shape the different development patterns of privacy self-efficacy. Understanding the different cultural practices may then shed light on the social sources of privacy competence and the appropriate remedies that can be provided to improve the situation. (shrink)

The meshed control theory assumes that cognitive control and automatic processes work together in the natural attention of experts for superior performance. However, the methods adopted by previous studies limit their capacity to provide in-depth information on the neuromotor processes. This experiment tested the theory with an alternative approach. Twelve skilled golfers were recruited to perform a putting task under three conditions: (1) normal condition, with no focus instruction (NC), (2) external focus of attention condition (EC), and (3) internal focus (...) of attention condition (IC). Four blocks of 10 putts each were performed under each condition. The putting success rate and accuracy were measured and electroencephalographies (EEGs) were recorded. The behavioral results showed that the NC produced a higher putting success rate and accuracy than the EC and IC. The EEG data showed that the skilled golfers’ attentional processes in the NC initially resembled those in the EC and then moved toward those in the IC just before putting. This indicates a switch from more automatic processes to cognitive control processes while preparing to putt. The findings offer support for the meshed control theory and indicate the dynamic nature of neuromotor processes for the superior performance of athletes in challenging situations. (shrink)

Evidence supports predictive roles of non-social smartphone use for smartphone addiction, but the relationship of social smartphone use and smartphone addiction is unclear. This study explored whether social smartphone use has a double-edged impact on smartphone addiction. Using data from a sample of 909 Chinese undergraduates, we tested a parallel mediation model that considered online social support and realistic social support as mediators. As predicted, social smartphone use weakened smartphone addiction through realistic social support and contributed to smartphone addiction through (...) online social support. Moreover, we tested the moderating role of agreeableness in the mediation path of online social support. Agreeableness only moderated the indirect effects. Specifically, the predictive effects of online social support on smartphone addiction was greater for lower rather than higher agreeableness. The results suggest that social needs play an important role in the formation of smartphone addiction. Several limitations and implications are also discussed herein. (shrink)

Do experiences with nature –– from wilderness backpacking to plants in a preschool to a wetland lesson on frogs, promote learning? Until recently, claims outstripped evidence on this question. But the field has matured, not only substantiating previously unwarranted claims but deepening our understanding of the cause-and-effect relationship between nature and learning. Hundreds of studies now bear on this question, and converging evidence strongly suggests that experiences of nature boost academic learning, personal development, and environmental stewardship. This brief integrative review (...) summarizes recent advances and the current state of our understanding. The research on personal development and environmental stewardship is compelling although not quantitative. Report after report –– from independent observers as well as participants themselves –– indicate shifts in perseverance, problem-solving, critical thinking, leadership, teamwork, and resilience. Similarly, over fifty studies point to nature playing a key role in the development of pro-environmental behavior, particularly by fostering an emotional connection to nature. In academic contexts, nature-based instruction outperforms traditional instruction. The evidence here is particularly strong, including experimental evidence; evidence across a wide range of samples and instructional approaches; outcomes such as standardized test scores and graduation rates; and evidence for specific explanatory mechanisms and active ingredients. Nature may promote learning by improving learners’ attention, levels of stress, self-discipline, interest, and enjoyment in learning, and physical activity and fitness. Nature also appears to provide a calmer, quieter, safer context for learning; a warmer, more cooperative context for learning; and a combination of “loose parts” and autonomy that fosters developmentally beneficial forms of play. It is time to take nature seriously as a resource for learning — particularly for students not effectively reached by traditional instruction. (shrink)

Genetic cancer predisposition testing in the paediatric population poses unique ethical dilemmas. Using the hypothetical example of a teenager with cancer with a high probability of having an underlying cancer predisposition syndrome, we discuss the ethical considerations that affect the decision-making process. Because legally these decisions are made by parents, genetic testing in paediatrics can remove a child’s autonomy to preserve his or her own ‘open future’. However, knowledge of results confirming a predisposition syndrome can potentially be beneficial in modifying (...) treatment and surveillance plans and enabling at-risk family members to obtain cascade testing for themselves. Considering virtue ethics to envision the best characters of the patient, parents and healthcare providers can guide them to the better choice to test or not to test, with the ultimate goal of achieving the best outcome for survival andeudaimonia, human flourishing reliably sought out. (shrink)

While widely acknowledged as the world's oldest profession, and often glamorized or demonized in the media, prostitution is a critical part of American culture and its economy, as well as a social problem in need of an updated public policy. In Prostitution Policy, Lenore Kuo combines feminist social research and legal studies to tackle issues raised by heterosexual prostitution in the U.S. Through the lens of feminist theory, Kuo examines the milieu of prostitutes and the role of prostitution in contemporary (...) society, and how the interplay of those two works itself out in practice. Moving beyond theoretical analysis of prostitution, Prostitution Policy turns to the complicated problem of formulating a reasonable legal policy that minimizes harm. Kuo discusss criminalization, legalization, and decriminalization as possible approaches, ultimately arguing for a unique form of decriminalization including detailed legal oversight and mandatory social services. (shrink)

An institutional auditing program typically consists of the following steps: a sample audit, the decision to move to the full audit, a settlement offer, and the full audit. Statistical sampling techniques are often used to estimate the overbilling percentage and amount. This paper discusses the optimal settlement offer, the net recovery through auditing, the condition for the auditors to move to the full audit, and how an auditing program can be truly cost-effective. This paper provides an evaluation for the statistical (...) sampling techniques to an auditing program. The economic incentives of a contractor to overbill are also identified. Finally, it presents the key metrics and the managerial implications for auditing managers to design or enhance their auditing programs. (shrink)

Reflecting on the tension of which he was aware between the imperial West and the still-mysterious East, Victorian writer Rudyard Kipling penned the above phrase to express the incommensurable situation wherein the Westerner never understands the Asian, as the latter’s culture differs too greatly from his own. However, aware that East and West nevertheless cannot remain separated forever, the author ends the poem with an eventual encounter between the two.Over 100 years have passed since this poem was written, yet the (...) ambivalent encounter between East and West that it depicts still exists and is currently playing out within the field of pharmaceuticals. On one side of the divide are the many people in the industry who want to standardize global acceptance of drugs; on the other are the local authorities who want to maintain the overruling legal need not to compromise on health care at a national level. In this sense, the divergence and unity that Kipling captures is what this paper aims to discuss as it addresses how race is debated at the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use. (shrink)

Concerns with improper collection and usage of personal information by businesses or governments have been seen as critical to the success of the emerging electronic commerce. In this regard, computer professionals have the oversight responsibility for information privacy because they have the most extensive knowledge of their organization's systems and programs, as well as an intimate understanding of the data. Thus, the competence of these professionals in ensuring sound practice of information privacy is of great importance to both researchers and (...) practitioners. This research addresses the question of whether male computer professionals differ from their female counterparts in their self-regulatory efficacy to protect personal information privacy. A total of 103 male and 65 female subjects surveyed in Taiwan responded to a 10-item questionnaire that includes three measures: protection (protecting privacy information), non-distribution (not distributing privacy information to others), and non-acquisition (not acquiring privacy information). The findings show (1) significant gender differences exist in the subjects' overall self-regulatory efficacy for information privacy, and, in particular, (2) that female subjects in this study exhibited a higher level of self-regulatory efficacy than males for the protection and non-acquisition of personal privacy information. The identification of the factorial structure of the self-regulatory efficacy concerning information privacy may contribute to future research directed to examining the links between privacy efficacy and psychological variables, such as ethical attitude, ethical intention, and self-esteem. Studies can also be extended to investigate how different cultural practices of morality and computer use in men and women may shape the different development patterns of privacy self-efficacy. Understanding the different cultural practices may then shed light on the social sources of privacy competence and the appropriate remedies that can be provided to improve the situation. (shrink)

Looking closely into how the differences among populations are debated at the ICH, this paper aims to provide a comprehensive account on what actually occurs when states with different cultural backgrounds encounter one another at the frontier of pharmaceutical regulation, where neither West nor East shall exist.

Jeremy sustained bilateral complete brachial plexus injuries in an auto collision on an icy road a month before his third birthday. The accident rendered both upper extremities completely flail and insensate: he has no motor or sensory function of his shoulders, elbows, wrists, or digits. Jeremy does, however, have normal function of the lower extremities. Physical therapists have worked with the child for over a year with no noted improvement in arm function. Jeremy falls frequently, causing injury to his face (...) and head, and occasionally, his arms get twisted or caught in his crib and his fingers turn blue. Jeremy's mother, who carries the main responsibility for his daily care, believes that his insensate arms are too heavy and “get in his way,” causing the falls. She and Jeremy's father present to the orthopedic clinic at the children's hospital with the request of having both arms amputated. The primary orthopedic surgeon and the orthopedic team disagree with the parents that bilateral upper-extremity amputation offers any medical benefit, but Jeremy's mother tells the surgeon that, if he will not perform the surgery, her family will find a doctor who will. The surgeon, who feels ethically distressed by the parental insistence on this amputation in such a young child, requests an ethics consultation. (shrink)

Reformed catholicity suffers from a fragility that causes it to easily fragment over comparatively small differences. This study wagers that an important resource that can be useful for addressing this problem is the Chinese philosophy of tianxia. The article introduces the idea of a ‘Reformed catholicity under Heaven’ by placing a more liberal interpretation of tianxia in conversation with the problems in Reformed approaches to the church’s catholicity. In doing so, the article demonstrates tianxia’s ecclesiological usefulness while articulating two dimensions (...) of ‘Reformed catholicity under Heaven’ that can deepen how Reformed churches inhabit catholicity in ways that promote unity. (shrink)

In this article, we discuss the ethical dimensions for the prescribing behaviours of opioids for a chronic pain patient, a scenario commonly witnessed by many physicians. The opioid epidemic in the USA and Canada is well known, existing since the late 1990s, and individuals are suffering and dying as a result of the easy availability of prescription opioids. More recently, this problem has been seen outside of North America affecting individuals at similar rates in Australia and Europe. We argue that (...) physicians are also confronted with an ethical crisis where a capitalist-consumerist society is contributing to this opioid crisis in which societal, legal and business interests push physicians to overprescribe opioids. Individual physicians often find themselves unequipped and unsupported in attempts to curb the prescribing of opioid medications and balance competing goals of alleviating pain against the judicious use of pain medications. Physicians, individually and as a community, must reclaim the ethical mantle of our profession, through a more nuanced understanding of autonomy and beneficence. Furthermore, physicians and the medical community at large have a fiduciary duty to patients and society to play a more active role in curbing the widespread distribution of opioids in our communities. (shrink)

This study constitutes an ethical analysis through the lens of distributive justice in the case of the Troubled Asset Relief Program (TARP), which was enacted in the midst of the Great Recession of 2007–2009. It begins by engaging with the visions of justice constructed by John Rawls and Robert Nozick, using their insights to locate the injustices of TARP according to their moral imaginations. However, this study argues that Rawls’ and Nozick’s theories of justice primarily envision the nature of law (...) as being restrictive of vice, not as instructors of virtue. Thus, it resources the legal philosophy of St. Thomas Aquinas to demonstrate how the positive pedagogy of law can enable a more just construction of economic rescue legislation, one that not only prevents future repetitions of economic vices and injustice, but is also formative for a society that prizes economic justice and virtues. In doing so, the study proposes two criteria for a more just consideration of economic rescue legislation that embraces law’s positive pedagogy. (shrink)

Acetylation of internal lysine residues of core histone N-terminal domains has been found correlatively associated with transcriptional activation in eukaryotes for more than three decades. Recent discoveries showing that several transcriptional regulators possess intrinsic histone acetyltransferase (HAT) and deacetylase (HDAC) activities strongly suggest that histone acetylation and deacetylation each plays a causative role in regulating transcription. Intriguingly, several HATs have been shown an ability to acetylate nonhistone protein substrates (e.g., transcription factors) in vitro as well, suggesting the possibility that internal (...) lysine acetylation of multiple proteins exists as a rapid and reversible regulatory mechanism much like protein phosphorylation. This article reviews recent developments in histone acetylation and transcriptional regulation. We also discuss several important, yet unanswered, questions. BioEssays 20:615–626, 1998. © 1998 John Wiley & Sons Inc. (shrink)

Drawing upon Hannah Arendt's and Carl Schmitt's theories on the relationship between nomos and boundary, this paper revisits how constitutionalism and political power are reconciled as constitutional ordering. It first analyzes constitutionalism in the light of political modernity. Indicating that political power grounded by constitutions is omnipotent, complementing and completing constitutionalism, the paper contends that an omnipotent constitutional ordering is anything but an unleashed Leviathan. It is argued that constitutional omnipotence is framed and thus constrained by a constitutional nomos, the (...) matrix of which is a dual delimitation of boundaries, generational, and jurisdictional. (shrink)

Reformed ecclesiology suffers from a lack of a concrete sense of catholicity, a lack that easily shatters unity in the church. This article broadly sketches a way in which Reformed confessions and the practice of confessing can help fill that lack, drawing from Robert Schreiter's The New Catholicity. By understanding confessing in terms of remembering dangerous memories, Reformed catholicity has the potential for enabling the church to be a unifying witness in an age where globalizing forces have fragmented societies and (...) inflamed troubling sentiments. (shrink)

The purpose of this dissertation is to present and defend a view regarding the freedom of human action which I call "Causationism," a view which incorporates some of the more fundamental commitments of traditional Determinism while allowing for the possibility of statistically regular actions or components of actions. Premise I of Causationism essentially maintains that all human actions are caused either by statistical regularities or deterministically. The inclusion of statistically regular events or components of actions in a causal account is (...) based on an appeal to the Dretske-Snyder thesis of "Causal Irregularity." Premise II of Causationism is essentially identical to the Incompatibility Thesis of traditional Determinism. My theory then proceeds along traditional Deterministic lines, concluding with the claim that "No one is morally responsible for his or her actions." ;Premise I is defended by appeal to empirical evidence. It is then demonstrated that traditional Libertarian arguments intended to weaken the force of this evidence fail. ;In Chapter III, I consider objections to the Incompatibility Thesis. I argue that a hypothetical reading of "he could have done otherwise" not only fails to capture what we mean when we speak of an individual's "acting freely," but also that a hypothetical reading of this phrase fails to provide a sufficient condition for a morally relevant sense of "freedom." ;In Chapter IV, I argue, by appeal to the concept of "novelty" and to Davidson's Mind/Body Theory, that, contrary to the opinion of some philosophers, an event's being caused does not require that it be predictable or subsumable under statements of probability expectations. ;Chapter V addresses the claim that if all actions are caused, then no action can be rational. A variety of arguments are formulated to demonstrate that various versions of the "Determinist Dilemma" fail. ;Finally, in Chapter VI, I argue that adoption of Causationism does not destroy morality although the denial of moral responsibility significantly alters traditional morality and requires a reanalysis of certain basic ethical terms. I offer the required reanalyses and consider the ramifications of their adoption to ethical theory. (shrink)

This paper first argues that a state can justifiably fight a hopeless war of self-defense when its enemy determines to massacre its people after it surrenders or is defeated. The main reason is that, in this situation, even if the victim state surrenders, it still has to suffer from harms that are similar to or worse than the harms involved in fighting a hopeless war. This paper then discusses some complicated issues raised by applying this argument to various situations in (...) which the victims of war and the victims of massacre are not identical. I argue that, when the victims of massacre are randomly chosen, the victim state can justifiably fight such a war. When the victims of massacre belong to a specific group of people, the victim state should not fight such a war, even though the victims of massacre can defend themselves. This paper finally comments on an alternative approach to addressing the same issue. (shrink)

Confucius is conventionally regarded as the founder of secular humanism and as a philosopher concerned about humans and culture. I would add to this that Confucius should also be read as an environmental philosopher. One reason is the pedagogical dimension in Confucianism, which points to Confucius as an environmental educator ? not the least of which since much of environmental education relies on common sense and an enlightened collective self-interest. Another reason is an aspect I call ?ecological intelligence?, which is (...) a key feature of ancient Confucianism and a signpost for the civil evolution that the mitigation of climate change demands from global civilization today. (shrink)

The defeat of the Constitutional Treaty by French and Dutch voters in 2005 and the following stalemate of the Lisbon Treaty have sparked a soul-searching process for European constitutional scholarship. Among the numerous academic efforts devoted to contemplating the future of European constitution, Michelle Everson and Julia Eisner's The Making of a European Constitution: Judges and Law Beyond Constitutive Power deserves a close look. Everson and Eisner argue for a postconstituent view of European constitutionalization, which they call ‘Rechtsverfassungsrecht’. Departing from (...) the myth of the constituent power, they interpret the development of a European constitution as a self-creating process by which the ordinary legal system gives itself a set of core values and thereby remakes itself into a constitutional order. Moreover, against the criticisms of juridification, they defend this lawyer-centred process of European constitutionalization as incorporating politics into the daily operation of the legal system. Engaging with Everson and Eisner's argumentation, I argue that their account of European constitutional development does not so much put out a realist theory of the EU constitutionalization as sets out a realist academic lawyering for the next round of European constitutional politics, which is shared among European constitutional scholars. Contrasting this community-based legal profession in Europe with the situation of epistemic pluralism in American jurisprudence, in this article I observe that a lawyer-centred European constitutional theory as Everson and Eisner's book illustrates is premised on an inherited consensus that has held a European legal profession together. However, this lawyer-centred account of European constitutionalization presumes either the projection of a professional community onto a Europe-wide civic culture or the self-appointment of legal professionals as the fiduciary of the citizenry. Each is a fiction, however. This fictional character of the legalist-constructivist strategy to European constitutional politics is the underlying cause of the dilemma facing European constitutional ordering. (shrink)

Based on 24 hours of videotaped data, this study investigates, both qualitatively and quantitatively, gender differences in the use of person pronouns in televised sports in Taiwan. This analysis has found that, regardless of their speaker role, male sports reporters use the second-person singular pronoun nimuch more frequently than their female counterparts. In addition, there is a significant difference in the distribution ofpragmatic functions of nibetween men’s and women’s reporting. While male sports reporters use niin a more varied way, i.e. (...) to refer to the TV audience, a specific athlete or team, an indefinite or non-specific athlete, or to include this pronoun in direct speech to dramatize their reporting, female reporters use this pronoun predominately to referto a non-specific athlete. In other words, male sports reporters tend to employ impersonal niand dramatic nito signal their strong self-involvement, their interpersonal involvement with the athlete and the TV audience, and their involvement with the reported sports event. Finally, malesports reporters’ more frequent use of the second-person pronoun niin the data also marks their informal and conversational speech style.This result contradicts those previous studies which claim that formality and detachment characterize men’s information-oriented public discourse. (shrink)

Based on video-taped data from five televised 1998 Taipei mayoral debates, this article examines the use of reported speech in Chinese political discourse, with a particular focus on direct quotation. The findings are that direct quotation or constructed dialogue not only creates the rhetorical effect of vividness and immediacy but also establishes interpersonal involvement. More importantly, the three debaters in this study use direct quotation as an indirect strategy for self-promotion and for denigration. Citing someone else's words objectifies debaters' praise (...) of themselves and vilification of their opponents, thereby heightening the reliability of their claims: these claims are presented as shared knowledge and reference is made to an external source. However, direct quotation is also a strategy of evasion: the speakers disclaim responsibility and distance themselves from the source of knowledge. Finally, the different use of citations made by the three debaters also marks their different communicative styles. While the two politicians who speak more formally generally tend to cite figures from newspapers or magazines, the one who speaks most casually frequently employs direct quotations. (shrink)

Adopting Fairclough's multidimensional approach, this corpus-based study explores discursive changes in current Taiwanese society, with a particular focus on conversationalization in printed media. Data were collected from three major newspapers catering to different readerships during three time periods. The analyzed linguistic features include noun phrases, Chinese four-character set expressions, mixing of local dialect, and slang. My analysis shows that over the past two decades there has been an increase of conversational features in all three newspapers. In addition, a cross-sectional comparison (...) has revealed that soft news texts include more conversational features than hard news texts. It is also found that the newspaper which stresses local values and advocates an independent Taiwan identity tends to adopt more conversational features, particularly the mixing of Taiwanese in Mandarin news texts. Finally, I suggest that this trend of conversationalization in the Taiwanese press can be linked to substantive democratization and marketization of the Taiwanese society as well as the change and development of modern written Chinese. (shrink)

This study applies identity and social identity theories to develop and test a framework in which retail brand personality influences consumer outcomes [i.e., positive word-of-mouth about and patronage intention toward the retailer] through public and/or private self-congruity, strengthened by shopping conspicuousness situation, and retail brand identification. This is the first study to include social shopping situations to study brand personality and self-congruity. A questionnaire with a 2 × 2 between-subjects design was conducted on a sample of US consumers. Structural equation (...) modeling was used to test the hypotheses. The findings suggest a framework in which Genuine, the most influential dimension of retail brand personality, predicted outcome behaviors both directly and indirectly through self-congruities and RBI. The high shopping conspicuousness situation strengthened the relationship between public self-congruity and the overall RBI. The concept of RBI provides an additional theoretical perspective for guiding future research on shopper–brand relationships. In addition, this framework provides practical implications for retail environment design and customer-brand relationship management. (shrink)

The concept of self-efficacy is concerned with people''s beliefs in their ability to produce given attainment. It has been widely applied to study human conduct in various settings. This study, based on Albert Bandura''s social cognitive theory, proposes the employment of self-efficacy for investigating people''s ethical conduct related to computer use. Specifically, an ethical computer self-efficacy (ECSE) construct concerning software piracy is developed and validated. The measurement model of the construct was rigorously tested and validated through confirmatory factor analysis. The (...) results suggest that ECSE can be operationalized as a second-order factor model. The first order constructs are termed use&keep (do not use), distribution (do not distribute), and persuasion (persuade others not to commit piracy). These factors are governed by a second-order construct of ECSE. This construct could be useful to research a wide range of information ethics in the future. (shrink)

New types of artificial intelligence products are gradually transferring to voice interaction modes with the demand for intelligent products expanding from communication to recognizing users' emotions and instantaneous feedback. At present, affective acoustic models are constructed through deep learning and abstracted into a mathematical model, making computers learn from data and equipping them with prediction abilities. Although this method can result in accurate predictions, it has a limitation in that it lacks explanatory capability; there is an urgent need for an (...) empirical study of the connection between acoustic features and psychology as the theoretical basis for the adjustment of model parameters. Accordingly, this study focuses on exploring the differences between seven major “acoustic features” and their physical characteristics during voice interaction with the recognition and expression of “gender” and “emotional states of the pleasure-arousal-dominance (PAD) model.” In this study, 31 females and 31 males aged between 21 and 60 were invited using the stratified random sampling method for the audio recording of different emotions. Subsequently, parameter values of acoustic features were extracted using Praat voice software. Finally, parameter values were analyzed using a Two-way ANOVA, mixed-design analysis in SPSS software. Results show that gender and emotional states of the PAD model vary among seven major acoustic features. Moreover, their difference values and rankings also vary. The research conclusions lay a theoretical foundation for AI emotional voice interaction and solve deep learning's current dilemma in emotional recognition and parameter optimization of the emotional synthesis model due to the lack of explanatory power. (shrink)

Online reading is developing at an increasingly rapid rate, but the debate concerning whether learning is more effective when using hypertexts than when using traditional linear texts is still persistent. In addition, several researchers stated that online reading comprehension always starts with a question, but little empirical evidence has been gathered to investigate this claim. This study used eye-tracking technology and retrospective think aloud technique to examine online reading behaviors of fifth-graders ( N = 50). The participants were asked to (...) read four texts on the website. The present study employed a three-way mixed design: 2 (reading ability: high vs. low) × 2 (reading goals: with vs. without) × 2 (text types: hypertext vs. linear text). The dependent variables were eye-movement indices and the frequencies of using online reading strategy. The results show that fifth-graders, irrespective of their reading ability, found it difficult to navigate the non-linear structure of hypertexts when searching for and integrating information. When they read with goals, they adjusted their reading speed and the focus of their attention. Their offline reading ability also influenced their online reading performance. These results suggest that online reading skills and strategies have to be taught in order to enhance the online reading abilities of elementary-school students. (shrink)

This commentary reflects on recent instances of anti-Asian violence and state responses to redress violence through data-driven strategies. Data collection often presents itself as an appealing strategy, due to impacted communities’ desires for evidence and metrics to substantiate political claims. Yet, data collection can bolster the carceral state. This commentary takes an antagonistic approach to policing, including the ongoing creation of data infrastructures by—and for—law enforcement through hate crimes legislation. We critically discuss the challenges and possibilities in building towards anti-carceral (...) responses amidst ongoing racial violence and crisis. (shrink)

From the popularity of flipped teaching in United States primary and high schools, it is thought that students have more learning control to adjust to the learning progress and are assisted in problem solving and learning guidance during class period. It is believed that flipped teaching could prompt underachieving learners’ active learning and thereby enhance learning effectiveness. A total of 386 high school students in Chungli, Taiwan, were part of an experimental study and the research results are summarized below: Students (...) who participated in the flipped teaching models demonstrated better comprehension levels with the teaching content due to this change in learning style and attitude, which in turn, enhanced learning effectiveness. To eliminate poor language performance of underachieving students, it is necessary to lay solid foundations to gradually enhance language learning effectiveness regarding this particular group of students. Films suitable for students’ individual ability could be combined with new language learned in the unit to genuinely assist underachieving learners’ language learning effectiveness. For students who care about their performance, a “system of play” style grouping should be determined in order to enable the tracking of group performance and term performance. According to the results, further developments regarding active learning ability, boosts in learning interests, enhanced learning effectiveness, and the prompting of creativity resulting in a shift from passive learner to active learner have been proposed. (shrink)

The goal of this article is attempting to establish a research tradition of Chinese relationalism on the methodological grounds of constructive realism. Two of Ho’s key concepts, person-in-relations and persons-in-relation, are carefully examined and reinterpreted. Three of my theoretical models, namely, my Face and Favor model , Confucian ethics for ordinary people , and a conflict resolution model , are conceived of as microworlds for illustrating an account of person-in relations in Chinese culture. The manifestation of Confucian ethics for ordinary (...) people in one’s lifeworld results in the phenomenology of persons-in-relations as depicted by Fei’s differential order or Hsu’s psychosociogram. Applying constructive realism to my models and using the result as a framework for studying Chinese social behavior constitutes Chinese relationalism. (shrink)

The author proposes an epistemological strategy to resolve controversial issues in the indigenous psychology movement. These include the nature of IPs, scientific standards, cultural concepts, philosophy of science, mainstream psychology, generalization of findings, and the isolation and independence of IPs. The approach includes a two-step strategy for construction of culture-inclusive theories, based on a Mandala model of self and a Face and Favor model for social interaction, and the use of these models to develop culture-inclusive theories for Confucian morphostasis. The (...) author has successfully used this strategy, and encourages others to use it to construct their own culture-inclusive theories. (shrink)

© Ginn et al. 2016.The indexing methods currently used for serial femtosecond crystallography were originally developed for experiments in which crystals are rotated in the X-ray beam, providing significant three-dimensional information. On the other hand, shots from both X-ray free-electron lasers and serial synchrotron crystallography experiments are still images, in which the few three-dimensional data available arise only from the curvature of the Ewald sphere. Traditional synchrotron crystallography methods are thus less well suited to still image data processing. Here, a (...) new indexing method is presented with the aim of maximizing information use from a still image given the known unit-cell dimensions and space group. Efficacy for cubic, hexagonal and orthorhombic space groups is shown, and for those showing some evidence of diffraction the indexing rate ranged from 90% to 151%. Here, the indexing rate refers to the number of lattices indexed per image. (shrink)

The advent of intelligent technologies, notably Brain–Computer Interfaces (BCIs), has introduced novel privacy dilemmas. Ensuring judicious privacy transfer is imperative for the application of BCI technology and pivotal for fostering economic and technological progress. This study adopts privacy transfer as the research perspective and employs an ethical matrix as the research method. It establishes BCI users as the central core interests, with marketers, developers, and medical personnel as stakeholders. Departing from the binary opposition of public and private in traditional privacy (...) theory, this article proposes ethical principles such as maximizing benefits, minimizing harm, and respecting independent decision-making power. It constructs a judgment matrix for the privacy transfer of BCIs, utilizing this matrix to identify ethical risks like privacy disclosure and hijacking. This study analyzes the reasons for risks, aiming to overcome dilemmas and construct an ethical matrix to explore privacy transfer boundary division methods suitable for BCI technology and tailored to different stakeholders. (shrink)

BackgroundImplementation of recommendations from clinical practice guidelines is essential for evidence based clinical practice. However, the most effective methods of implementation are unclear. We conducted a national, cluster-randomised, blinded implementation trial to determine if midwife or doctor local implementation leaders are more effective in implementing a guideline for use of oral dextrose gel to treat hypoglycaemic babies on postnatal wards. To prevent any conscious or unconscious performance bias both the doctor and midwife local implementation leaders were kept unaware of the (...) trial. This paper reports the ethical dilemmas and practical challenges of ensuring clinicians remained unaware of their involvement in an implementation trial.MethodsWe sought approval from the National Health and Disability Ethics committee to keep clinicians unaware of the trial by waiving the standard requirement for locality approval usually required for each district health board. The ethics committee did not approve a waiver of consent but advised that we approach the chief executive of each district health board to ask for provisional locality approval. Ultimately it was necessary to seek ethics approval for three separate study designs to keep clinicians unaware of the trial.ResultsThe median time for chief executive approval was 16 days and for locality approval was 57 days. We completed 21 different locality approval forms for 27 hospitals.ConclusionsKeeping clinicians unaware of their involvement in a national implementation cluster-randomised trial is feasible. However, despite a national ethics committee, significant logistical challenges were time consuming and delayed trial completion. Co-ordination of the locality approval process would help facilitate multi-centre trials. (shrink)

The three approaches for conducting psychological research across cultures proposed by Berry , namely, the imported etic, emic and derived etic approach are critically examined for developing culture-inclusive theories in psychology, in order to deal with the enigma left by Wilhelm Wundt. Those three approaches have been restricted to a certain extent by the pan-cultural dimensional approach which may result in the Orientalism of psychology in understanding people of non-Western cultures. This article is designated to provide the philosophical ground for (...) an alternative cultural system approach to construct culture-inclusive theories in psychology. Following the principle of cultural psychology: “one mind, many mentalities” , the alternative strategy contains two steps: First, based on Bhaskar's critical realism, all universal mechanisms should seek to represent the operation of the human mind. Second, based on Archer's analytical dualism, the mechanisms of the universal mind may be used as frameworks for analyzing any cultural tradition. The culture-inclusive theories thus obtained represent the synchronic morphostasis of a cultural system, which may be used as theoretical frameworks for conducting either qualitative or quantitative empirical research in studying the diachronic morphogenesis of socio-cultural interaction in a particular culture. (shrink)

In the paper, several data reduction techniques for machine learning from big datasets are discussed and evaluated. The discussed approach focuses on combining several techniques including stacking, rotation, and data reduction aimed at improving the performance of the machine classification. Stacking is seen as the technique allowing to take advantage of the multiple classification models. The rotation-based techniques are used to increase the heterogeneity of the stacking ensembles. Data reduction makes it possible to classify instances belonging to big datasets. We (...) propose to use an agent-based population learning algorithm for data reduction in the feature and instance dimensions. For diversification of the classifier ensembles within the rotation also, alternatively, principal component analysis and independent component analysis are used. The research question addressed in the paper is formulated as follows: does the performance of a classifier using the reduced dataset be improved by integrating the data reduction mechanism with the rotation-based technique and the stacking? (shrink)

Virtual reality has developed rapidly, drawing more businesses to such development. Based on the diffusion of innovations theory, the study combines the flow theory and the satisfaction perspective to explore purchase intention influencing customers’ adoption of the VR shopping platform system. This study found that satisfaction and flow experience enhance their purchase intention. In technological characteristics, relative advantage, service compatibility, spatial presence, and complexity are important in satisfaction. Among them, both relative advantage and spatial presence impact flow experience. Additionally, a (...) cluster analysis based on gender was conducted, and the study found a significant difference between relative advantages, service compatibility, and complexity in women and men users. The flow experience is an important factor affecting women users’ shopping intention, while insignificant for male users. The implications of these findings are discussed. (shrink)