In the perceptual learning of lexical tones, an automatic and robust attention-to-phonology system enables native tonal listeners to adapt to acoustically non-optimal speech, such as phonetic conflicts in daily communications. Previous tone research reveals that non-native listeners who do not linguistically employ lexical tones in their mother tongue may find it challenging to attend to the tonal dimension or integrate it with the segmental features. However, it is unknown whether the attentional interference initially caused by a maternal attentional system would (...) continue influencing the non-optimal tone perception for simultaneous bilingual teenagers. From an endpoint in the age of language acquisition, we investigate whether the tone-specific attention mechanism developed by the Urdu-Cantonese simultaneous bilinguals is automatic enough to assist them in adapting to a phonetically-conflicting environment. Three groups of teenagers engaged in a four-condition ABX task: Urdu-Cantonese simultaneous bilinguals, Cantonese native listeners, and Urdu-speaking, late learners of Cantonese. The results showed that although the simultaneous bilinguals could phonologically process Cantonese tones in a Cantonese-like way under a conflict-free listening condition, they still failed in adapting to the phonetic conflicts, especially the segment-induced ones. It thus demonstrated that the simultaneous exposure and years of regular education in Hong Kong local schools still could not automatically guarantee simultaneous bilingual processing of Cantonese tones. In interpreting the findings, it hypothesized that, except for simultaneous exposure, the development of a tone-specific attention mechanism is also likely to be L1-inhibitory, tone experience-driven, and language-specific for simultaneous bilinguals. (shrink)

ObjectivePrevious studies have demonstrated altered brain activity in strabismic amblyopia. In this study, low-frequency repetitive transcranial magnetic stimulation was applied in children with strabismic amblyopia after they had undergone strabismus surgery. The effect of rTMS was investigated by measuring the changes of brain features using the amplitude of low-frequency fluctuation.Materials and MethodsIn this study, 21 SA patients were recruited based on their age, weight, and sex. They all had SA in their left eyes and they received rTMS treatment one month (...) after strabismus surgery. Their vision before and after surgery were categorized as pre-rTMS and post-rTMS. All participants received rTMS treatment, underwent magnetic resonance imaging, and their data were analyzed using the repeated measures t-test. The team used correlation analysis to explore the relationship between logMAR visual acuity and ALFF.ResultsPre- versus post-rTMS values of ALFF were significantly different within individuals. In the POT group, ALFF values were significantly decreased in the Angular_R, Parietal_Inf_L, and Cingulum_Mid_R while ALFF values were significantly increased in the Fusiform_R and Frontal_Inf_Orb_L compared to the PRT stage.ConclusionOur data showed that ALFF recorded from some brain regions was changed significantly after rTMS in strabismic amblyopes. The results may infer the pathological basis of SA and demonstrate that visual function may be improved using rTMS in strabismic amblyopic patients. (shrink)

The Zhoushu 《周書》 section of the Shangshu 《尚書》, reflecting on the dynastic changes from Xia to Shang and from Shang to Zhou, understands “heavenly mandate” as the common element that brings about all changes within a historical continuum. For Zhoushu, it is “heavenly mandate” that makes historical continuity possible. Furthermore, “heavenly mandate” is understood to manifest itself with the hopes of the common people and to be realized by the freewill of the king. Thus historical changes can be accommodated. The (...) Chinese idea of historical identity continued to be enriched after the Chun Qiu 春秋 Period. But in terms of its characteristic understandings of history, it remained much the same as in the Zhoushu: Interpreting history with a common element recognized therein, with the stress always on continuity though historical changes are accommodated from a humanist perspective. (shrink)

Understanding the neural basis of schizophrenia (SZ) is important for shedding light on the neurobiological mechanisms underlying this mental disorder. Structural and functional alterations in the anterior cingulate cortex (ACC), dorsolateral prefrontal cortex (DLPFC), hippocampus, and medial prefrontal cortex (MPFC) have been implicated in the neurobiology of SZ. However, the effective connectivity among them in SZ remains unclear. The current study investigated how neuronal pathways involving these regions were affected in first-episode SZ using functional magnetic resonance imaging (fMRI). Forty-nine patients (...) with a first-episode of psychosis and diagnosis of SZ—according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision—were studied. Fifty healthy controls (HCs) were included for comparison. All subjects underwent resting state fMRI. We used spectral dynamic causal modeling (DCM) to estimate directed connections among the bilateral ACC, DLPFC, hippocampus, and MPFC. We characterized the differences using Bayesian parameter averaging (BPA) in addition to classical inference (t-test). In addition to common effective connectivity in these two groups, HCs displayed widespread significant connections predominantly involved in ACC not detected in SZ patients, but SZ showed few connections. Based on BPA results, SZ patients exhibited anterior cingulate cortico-prefrontal-hippocampal hyperconnectivity, as well as ACC-related and hippocampal-dorsolateral prefrontal-medial prefrontal hypoconnectivity. In summary, spectral DCM revealed the pattern of effective connectivity involving ACC in patients with first-episode SZ. This study provides a potential link between SZ and dysfunction of ACC, creating an ideal situation to associate mechanisms behind SZ with aberrant connectivity among these cognition and emotion-related regions. (shrink)

BackgroundAt present, adherence to antipsychotic treatment is often poor, leading to the recurrence of symptoms. This increases the likelihood of the patient experiencing disability and thus increases the disease burden for the patient, their family, and society as a whole. However, to date, there is no clear evidence regarding the effect of medication adherence interventions on outcomes for patients with schizophrenia. Moreover, the traditional intervention methods are limited by manpower and resources in low- and middle-income countries. Recent studies have demonstrated (...) that increasing a patient’s level of self-compassion may improve their treatment adherence. Online mental health care interventions have advantages in terms of feasibility and acceptability for patients with schizophrenia. In this regard, a WeChat-based self-compassion training protocol to improve patient treatment adherence was designed in this study and will be evaluated in the future to determine its impact on patients with schizophrenia.MethodsThe protocol for the randomized controlled trial is based on the SPIRIT 2013 statement. This parallel RCT will aim to recruit 392 patients with schizophrenia who will be randomized at a 1:1 ratio into a 3-week intervention or control group. Both groups will receive routine care. The intervention group will also receive WeChat-based self-compassion training, which requires participants to complete three tasks every day, including a reading task, a meditation task, and a self-compassion journal task. The control group will receive WeChat-based psychological health education, which will only require participants to read positive articles about psychological health every day. Medication adherence, self-compassion, stigma, and social support will be measured at baseline, immediately after the intervention, and 3 weeks after the intervention. Program feasibility will be evaluated throughout the course of the study, and acceptability will be measured immediately after the intervention.Expected results:The intervention described here will address the barriers to accessing mental health care for people with schizophrenia, including patients’ desire for independent management, difficulty accessing providers, and concerns about privacy and stigma. The current study provides guidance for clinical nurses to carry out psychological intervention, with the ultimate aim of addressing the problems associated with a shortage of psychological professionals in low- and middle-income countries. (shrink)

The generation of isometric force at the hand can be mediated by activating a few motor modules. Stroke induces alterations in motor modules underlying steady-state isometric force generation in the human upper extremity. However, how the altered motor modules impact task performance remains unclear as stroke survivors develop and converge to the three-dimensional target force. Thus, we tested whether stroke-specific motor modules would be activated from the onset of force generation and also examined how alterations in motor modules would induce (...) changes in force representation. During 3D isometric force development, electromyographic signals were recorded from eight major elbow and shoulder muscles in the paretic arm of 10 chronic hemispheric stroke survivors and both arms of six age-matched control participants. A non-negative matrix factorization algorithm identified motor modules in four different time windows: three “exploratory” force ramping phases and the stable force match phase. Motor module similarity and between-force coupling were examined by calculating the scalar product and Pearson correlation across the phases. To investigate the association between the end-point force representation and the activation of the motor modules, principal component analysis and multivariate multiple linear regression analyses were applied. In addition, the force components regressed on the activation profiles of motor modules were utilized to model the feasible force direction. Both stroke and control groups developed exploratory isometric forces with a non-linear relationship between EMG and force. During the force matching, only the stroke group showed abnormal between-force coupling in medial-lateral and backward-forward and medial-lateral and downward-upward directions. In each group, the same motor modules, including the abnormal deltoid module in stroke survivors, were expressed from the beginning of force development instead of emerging during the force exploration. The PCA and the multivariate multiple linear regression analyses showed that alterations in motor modules were associated with abnormal between-force coupling and limited feasible force direction after stroke. Overall, these results suggest that alterations in intermuscular coordination contribute to the abnormal end-point force control under isometric conditions in the UE after stroke. (shrink)

BackgroundThe Basal ganglia (BG) played a crucial role in the brain-level mechanisms of chronic pain disorders. However, the functional changes of BG in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) are still poorly understood. This study investigated the BG subregions’ resting-state functional connectivity (rs-FC) in CP/CPPS patients compared with healthy controls.MethodsTwenty eight patients with CP/CPPS and 28 age- and education-matched healthy males underwent clinical measurements and 3T brain MR imaging, including T1-weighted structural images and resting-state functional imaging. The data were analyzed (...) by the seeded-based rs-FC analysis. Then, a machine learning method was applied to assess the feasibility of detecting CP/CPPS patients through the changed rs-FC.ResultsCompared with healthy males, patients presented decreased rs-FC between the BG subregions and right middle cingulate cortex, and correlated with pain (r = 0.51, p-uncorrected = 0.005) and urinary symptoms (r = –0.4, p-uncorrected = 0.034). The left superior temporal gyrus and right supramarginal gyrus showed decreased rs-FC with the BG subregions as well. The area under the receiver operating characteristic curve of 0.943 (accuracy = 80%, F1-score = 80.6%) was achieved for the classification of CP/CPPS patients and healthy males with support vector machine (SVM) based on the changed rs-FC.ConclusionThese findings provide evidence of altered BG subregions’ rs-FC in CP/CPPS, which may contribute to our understanding of the BG’s role in CP/CPPS. (shrink)

本书系作者一系列关于后现代理论衰落后新出现的批评流派的论文集。其内容和体例分为五编。第一编的两章分别对九十年代以来国际学术界关于后现代主义问题的讨论作出总结性的评述;第二编“后殖民主义”应当说是本书的 重点,在首先对后殖民理论的源起以及后殖民地文学的概况作一“鸟瞰式”的评价。.

本书从回忆母亲中医治病开始,一路写来,有中医的神奇、有中医的道理、有中医与西医的区别、有人生的智慧、有豁达的胸襟、有现代人常常忽略的东西、有不少值得深思的问题.

Yi Hwang is Korean giant Bo of Neo-Confucianism, Zhu Xi as their study to cases. He was the author severely criticized Wang Yangming. Lee Hwang and odd peak on the "four-terminal impassioned" debate, both sides quoted Zhu's literature as an argument, and from that perspective loyal to Zhu. However, in essence is, Yi Hwang on Mencius' four-terminal, "said Zhu interpretation presupposes a set of different teachings of Confucianism system architecture, though Mencius in line with the text, but out of Zhu (...) Xi's basic position. This is one of the most crucial question is: "truth" can activities? In Zhu's of Science, the reason why is gas, there are not only activities. Based on the literature that: Yi Hwang in the interpretation of Zhu Xi's theory of qi, intentionally or unintentionally give reasons when an activity, while escaping the structure of Zhu Xi of Science. As a leading representative of Korean Confucianism, Yi T'oegye generally adhered to Zhu Xi's philosophical viewpoint, also writing several essays criticizing Wang Yang-ming's differences with Zhu Xi. In the debate between Yi T'oegye and his contemporary, Ki Kobong on the "Four Buddings" and the "Seven Emotions," both sides appealed to Zhu Xi's texts in the belief that they were being faithful to Zhu Xi's standpoint. But in fact, Yi's interpretation of "Four Buddings" presupposes a philosophical framework that differs from that of Zhu Xi. In this Yi deviates from Zhu Xi's standpoint, although he remains faithful to Mencius' texts. The key point of this debate lies in the question of whether "li" can be active. In Zhu Xi's philosophical framework, "li" as the ontological ground for "qi" has mere being but not activity. In this paper I demonstrate that in his interpretation of Zhu Xi's doctrine of "li" and "qi," Yi unconsciously ascribes a kind of activity to "li "and hence deviates from Zhu Xi's original philosophical position. (shrink)

With the rise of the “humanitarian drone” in recent years, drones have become one of the most controversial public interest technologies that have gained increasing media attention. It is worth noting that, although there is a perception in the aid sector that drones hold the promise to reinvent the health supply logistics, to date, routine drone delivery is still relatively new and largely unproven. This paper presents a recent field study conducted in 2019, where drones were deployed in Malawi to (...) help address the last mile challenge in medical supply delivery, and where a noticeable mentality of “killing two birds with one stone” around the attempt of using drones in resource-poor settings is observed. The objective of the paper is to shed light, through a real-world case study and from the ethical perspective, on the impacts of implementing such a systemic change in the existing health supply chain systems. As conclusion, a call for more reflexive approaches for the critical examination, as well as more structured guidance for the responsible evaluation, of medical cargo drones is raised. (shrink)

Increasingly, humanitarian organizations across the globe have been implementing innovative technologies in their practice as they respond to the needs of communities affected by conflicts, disasters, and public health emergencies. However, technological innovation may intersect with moral values, norms, and commitments, and may challenge humanitarian imperatives. Through the examination of an empirical case study on drone mapping, this paper aims to explore three questions: (1) What are the dynamics between aid delivery and technological innovation in the humanitarian enterprise? (2) How (...) are structural problems addressed in an environment in which technology is being portrayed as a force for change? (3) What moral responsibilities towards vulnerable populations should humanitarian stakeholders bear when introducing innovative technologies in humanitarian action. Discussion revolves around the ideology of “technological utopia”, and the normative role of technology in the aid sector - to make substantive impacts, or to produce “success stories”. In conclusion, a call for rigorous ethical analysis to help foster value sensitive humanitarian innovation (VSHI) is made. (shrink)

Friedrich Nietzsche has emerged as one of the most important and influential modern philosophers. For several decades, the book series Monographien und Texte zur Nietzsche-Forschung (MTNF) has set the agenda in a rapidly growing and changing field of Nietzsche scholarship. The scope of the series is interdisciplinary and international in orientation reflects the entire spectrum of research on Nietzsche, from philosophy to literary studies and political theory. The series publishes monographs and edited volumes that undergo a strict peer-review process. The (...) book series is led by an international team of editors, whose work represents the full range of current Nietzsche scholarship. (shrink)

Mencius, who often spoke of ming in different senses among which only one can be taken as fate, upheld two doctrines of fate--moral determinism and blind, unalterable fate--but he was prone to apply the former to collective entities, and the latter to individual persons. This bi-level distinction, which is at variance with the non-distinction in both Moism and Taoism, exercised a profound influence upon the minds of later Confucians.

本书分为五大部分,首先简介鬼谷子的有关情况,然后以古今中外的有关事例为佐证,分别阐发鬼谷子关于成名立身的道理;应事处世的方法;测心知人的手段;交涉游说的艺术。.

This study presents a semantic analysis of how emotions and emotional experiences are described in Chinese. It focuses on conventionalized expressions in Chinese, namely compounds and idioms, which contain body-part terms. The body-part terms are divided into two classes: those denoting external body parts and those denoting internal body parts or organs. It is found that, with a few exceptions, the expressions involving external body parts are originally metonymic, describing emotions in terms of their externally observable bodily events and processes. (...) However, once conventionalized, these expressions are also used metaphorically regardless of emotional symptoms or gestures. The expressions involving internal organs evoke imaginary bodily images that are primarily metaphorical. It is found that the metaphors, though imaginary in nature, are not really all arbitrary. They seem to have a bodily or psychological basis, although they are inevitably influenced by cultural models. (shrink)

In Philosophical Investigations §244, Wittgenstein suggests that we understand avowals (first-person psychological utterances) as manifestations or expressions of the speaker's mental states. An interesting philosophical theory, called expressivism, then develops from this Wittgensteinian idea. However, neo-expressivists disagree with simple expressivists on whether avowals are at the same time assertions, which are truth-evaluable. In this paper, I pursue the expressivist debate about whether avowals must also be viewed as assertions. I consider and reject three neo-expressivist objections against simple expressivism. Then, I (...) offer my own account of why we should understand avowals as assertions. (shrink)

Epicurus famously argued that death cannot be bad for a person because only painful experiences or something that brings about them can be bad for people, but when a person dies, she cannot experience anything at all, let alone pain. If, as Epicurus argued, death is not something bad for us, then presumably, we have no reason to fear it. In contrast with Epicurus, however, contemporary philosophers of death generally subscribe to the deprivation account of the badness of death, which (...) allows that death can be comparatively bad for the one who dies. Still, many deprivation theorists believe that death, as merely comparatively bad, is not a fitting object of fear. Some of them argue that our attitudes would be unfitting if they respond to comparative value; while others contend that fear is not the kind of attitude that tracks comparative value. In this paper, I critically assess these arguments by deprivation theorists, and argue that, contrary to what these theorists claim, their arguments do not entail that death does not merit fear. (shrink)

Journal Name: Semiotica Issue: Ahead of print.

This book introduces the notions and methods of formal logic from a computer science standpoint, covering propositional logic, predicate logic, and foundations ...

国家社会科学基金项目获“高等学校优秀青年教师教学科研奖励计划资助”(TRAPOYT).

In Authority and Estrangement, Richard Moran provides a fascinating account of how we know what we believe that he calls the “transparency account.” This account relies on the transparency relation between the question of whether we believe that p and the question of whether p is true. That is, we can consider the former by considering the grounds for the latter. But Moran’s account has been criticized by David Finkelstein, who argues that it fails to explain how we know our (...) attitudes and emotions more generally. The aim of this paper is to show how Moran’s transparency account can be extended to meet this criticism by modifying it, using insights from Davidson’s view on attitudes and emotions. (shrink)

This study focuses on user experience from the perspective of big data to complete the aggregation, clustering, and visual presentation of knowledge. Using a combination of sample literature review, visualization technologies, knowledge map analysis, Carrot2 clustering, and other methodologies, this study intends to examine user experience from three perspectives: research state, hotspots, and trends. First, based on the double-map overlay, core institutions, core countries, core authors, core journals, and core references distribution research, the knowledge flow, research power, and research subjects (...) of user experience are analyzed. Secondly, through keyword clustering analysis, this research intuitively presents the research topics of user experience and reveals the research hotspots and the evolution path of research methods. Finally, with the help of the subject clustering algorithm, the emerging trends of user experience research are predicted: the immersive experience upgrade of multi-scenario integration, the innovative design of multi-role collaboration, and the cross-disciplinary interactive exploration of multi-discipline. Following this, the user experience knowledge map is constructed, providing a global view and macro-cognition for subsequent research. (shrink)