Since the Nuremberg trials (1947–1949), informed consent has become central for ethical practice in patient care and biomedical research. Codes of ethics emanating from the Nuremberg Code (1947) recognize the importance of protecting patients and research subjects from abuses, manipulation and deception. Informed consent empowers individuals to autonomously and voluntarily accept or reject participation in either clinical treatment or research. In some cases, however, the underlying mental or physical condition of the individual may alter his or her cognitive abilities and (...) compromise the informed consent process. This is particularly true in chronic psychiatric conditions such as Treatment-Resistant Depression (TRD), where individuals may fail to respond to traditional antidepressant treatments (e.g., psychotherapy, pharmacotherapy). Moreover, it may raise further concerns for an individual’s motivation to consent and the level of understanding of the treatment or research procedure. This paper focuses on the informed consent process for Vagus Nerve Stimulation (VNS) in the treatment of individuals diagnosed with TRD. Specifically, the paper addresses how depression may affect the decision-making capacity of an individual and the potential ethical and legal impact of failure to appreciate the seven elements of the consenting process (competence, voluntariness, disclosure, recommendation, understanding, decision, and authorization). To ensure the protection of vulnerable individuals with psychiatric disorders such as TRD and promote ethical behavior in biomedical research and patient care while avoiding potential legal pitfalls, we propose a paradigm that requires a stringent evaluation process of decision-making capacity for informed consent. (shrink)

L’éthique de la vertu d’Annas est confrontée à l’objection de la circularité. Annas affirme qu’une âme juste est disposée à poser des actes justes. On contourne l’objection de la circularité si l’on ne définit l’âme juste ni en termes d’actes bons, ni en termes de règles. En m’appuyant sur les récents travaux de Korsgaard, je démontre que l’argument d’Annas se heurte de nouveau à l’objection de la circularité. Ensuite, j’examine de quelle façon Annas tente une fois de plus d’éviter l’objection (...) de la circularité en faisant appel à la communauté des vertueux. Je soutiens que cette démarche ne préserve sa théorie ni du relativisme, ni de l’objection de la circularité. (shrink)

Cet article est fondé sur deux principes : le principe de partialité et le principe d’impartialité. M’appuyant sur un argument relativement peu connu de Kant, j’énonce et je défends le second principe. Je démontre ensuite que le premier principe est lié à la thèse présentée par Annas dans sa théorie sur l’éthique de la vertu, selon laquelle aucun adulte mûr ne souhaite qu’on lui dise quoi faire, ainsi qu’à son récit sur l’enseignement et l’apprentissage de la vertu. Je soutiens que (...) la théorie d’Annas sur l’éthique de la vertu est susceptible, contrairement à celle de Kant, de donner prise soit à l’objection de la circularité, soit à l’objection du relativisme. (shrink)

In the paper I examine (Section I) the best defense for the claim that methodologies shouldnot function heuristically (thesis-LW) as it appears in John Worrall. I then evaluate (Section II) his proposal of a criterion* M which is offered as a criterion for evaluating competing methodologies such as falsificationism, conventionalism, methodology of research programmes. etc. Finally, I consider (Section III) the consequences of arguments presented earlier (Section I and II) as they bear on the problem of selecting a historiographical model.I (...) argue, among other things, (I) that thesis-LW is defended on some very dubious assumptions; (II) that Worrall's criterion* M falters under three clear cases two of which at least*M should accomodate, and that part of* M's failure can be linked to its being hooked to thesis-LW. By arguments analogous to the ones which serve* M, I show thatcontra John Worrall and John Watkins, thesis-LW is testable; finally, (III) if we accept arguments for thesis-LW and* M we are left with a skeptical conclusion with respect to the choice of a historiographical model which Worrall by parity of reasoning should accept, but does not. (shrink)

Philosophy of history; the idea of the not-being and the history, by K. M. Jamil.--Philosophy of history, by Khwaja Ashkar Husain.--Philosophy of history, by A. H. Kamali.--Philosophy of history, by B. H. Siddiqi.--Philosophy of history: explanation in history, by Kazi A. Kadir.

Few modern artists so consistently embodied a fuzzy logic of their own as did the Indian painter Maqbool Fida Husain (1915 – 2011). His critics tried to define him as a reckless defamer of Hindu values, but another way to define him is as a dutiful devotee of a vision that was inclusive, rather than exclusive, and that understood all boundaries and identities as fluid or blurry, rather than as fixed and immutable. Or one might say that Husain (...) strove to project what Ashis Nandy has called “Indian-style secularism,” celebrating creation, humanity, and beauty in the multiple religious forms of the subcontinent. Having lived and painted in India all his life, he was forced into exile in his nineties by right-wing Hindu politicians. In London, he continued to work on a new interpretation of Indian civilization as universally relevant, in a sequence of paintings with themes from the Mahabharata, while, in Doha, a royal patron commissioned him to paint a series relating Islamic and Christian civilization. The two series are shown, in this essay, to best exhibit Husain's view of “all distinctions” as “political, artificial.”. (shrink)

This study described the relationships between academic class and student moral sensitivity and reasoning and between curriculum design components for ethics education and student moral sensitivity and reasoning. The data were collected from freshman (n = 506) and senior students (n = 440) in eight baccalaureate nursing programs in South Korea by survey; the survey consisted of the Korean Moral Sensitivity Questionnaire and the Korean Defining Issues Test. The results showed that moral sensitivity scores in patient-oriented care and conflict were (...) higher in senior students than in freshman students. Furthermore, more hours of ethics content were associated with higher principled thinking scores of senior students. Nursing education in South Korea may have an impact on developing student moral sensitivity. Planned ethics content in nursing curricula is necessary to improve moral sensitivity and moral reasoning of students. (shrink)

This paper aims at presenting the critique of both the quantitative and the qualitative research methodologies for social sciences in general and organizational sciences in particular. Quantitative and qualitative research models have been dominant over the second half of the twentieth century. Meanwhile, it has become a growing concern that a dichotomy between them should be overcome by combining them into a methodological pluralism. Positivism is the epistemological ground of quantitative methodology whereas phenomenology is the same with qualitative. It will (...) be argued that for methodological pluralism, neither positivism nor phenomenology can suffice alone. This paper presents a comparison and analysis of both positivism and phenomenology with the intention of working out their fundamental presuppositions. The purpose of this investigation is to look for the possibility of outlining a theoretic paradigm for the practice of methodological pluralism. (shrink)

Misconduct in medical science research is an unfortunate reality. Science, for the most part, operates on the basis of trust. Researchers are expected to carry out their work and report their findings honestly. But, sadly, that is not how science always gets done. Reports keep surfacing from various countries about work being plagiarised, results which were doctored and data fabricated. Scientific misconduct is scourge afflicting the field of science, unfortunately with little impact in developing countries like India especially in health (...) care services. A recent survey and a meta-analysis suggest that the few cases that do float up represents only tip of a large iceberg. This paper therefore highlights reasons for misconduct with steps that can be taken to reduce misconduct. Also the paper throws light on Indian scenario in relation to misconduct. (shrink)

This work focuses on the revival of Aristotlian thought in Europe. Dr Kassim discusses the influence of Aristotle in Muslim speculative thought, the emergence of a Neo-Aristotlian school in Cordoba, and the transmission of philosophic ideas via Jewish and Christian translators.

This paper is an update of the documents we have concerning the Acts of the Christian martyrs, focused on three main aspects: 1) the kind of acts we know of and their classification from the point of view of their historic value; 2) the versions or editions of the texts that are most accepted by scholars; 3) the relevance of the different parts that make up these documents in order to discern the original text from passages that were rewritten or (...) underwent later variations. In this way, the article offers an exhaustive list of the documents for use in researching Christian martyrs in the Roman period. (shrink)

Under what conditions is a group of scientists rational? How would rational scientists collectively agree to make their group more effective? What sorts of negotiations would occur among them and under what conditions? What effect would their final agreement have on science and society? These questions have been central to the philosophy of science for the last two decades. In this 2007 book, Husain Sarkar proposes answers to them by building on classical solutions - the skeptical view, two versions (...) of the subjectivist view, the objectivist view, and the view of Hilary Putnam. Although he finds these solutions not completely adequate, Sarkar retrieves what is of value from them and also expropriates the arguments of John Rawls and Amartya Sen, in order to weave a richer, deeper, and more developed theory of group rationality. (shrink)

Current views of the parietal cortex have difficulty accommodating the human inferior parietal lobe (IPL) within a simple dorsal versus ventral stream dichotomy. In humans, lesions of the right IPL often lead to syndromes such as hemispatial neglect that are seemingly in accord with the proposal that this region has a crucial role in spatial processing. However, recent imaging and lesion studies have revealed that inferior parietal regions have non-spatial functions, such as in sustaining attention, detecting salient events embedded in (...) a sequence of events and controlling attention over time. Here, we review these findings and show that spatial processes and the visual guidance of action are only part of the repertoire of parietal functions. Although sub-regions in the human superior parietal lobe and intraparietal sulcus contribute to vision-for-action and spatial functions, more inferior parietal regions have distinctly non-spatial attributes that are neither conventionally 'dorsal' nor conventionally 'ventral' in nature. (shrink)

This is a welcome reprint of a book that continues to grow in importance.

Scaffolds are fundamental to many cellular signaling pathways. In this essay, a novel class of scaffolds are proposed, whose action bears striking resemblance to kinetic proofreading. Commonly, scaffold proteins are thought to work as tethers, bringing different components of a pathway together to improve the likelihood of their interaction. However, recent studies show that the cytoskeletal scaffold, anillin, supports contractile signaling by a novel, non‐tethering mechanism that controls the membrane dissociation kinetics of RhoA. More generally, such proof‐reading‐like scaffolds are distinguished (...) from tethers by a rare type of cooperativity, manifest as a super‐linear relationship between scaffold concentration and signaling efficiency. The evidence for this hypothesis is reviewed, its conceptual ramifications are considered, and research questions for the future are discussed. (shrink)

Perhaps the most famous proposition in the history of philosophy is Descartes' cogito 'I think, therefore I am'. Husain Sarkar claims in this provocative interpretation of Descartes that the ancient tradition of reading the cogito as an argument is mistaken. It should, he says, be read as an intuition. Through this interpretative lens, the author reconsiders key Cartesian topics: the ideal inquirer, the role of clear and distinct ideas, the relation of these to the will, memory, the nature of (...) intuition and deduction, the nature, content and elusiveness of 'I', and the tenability of the doctrine of the creation of eternal truths. Finally, the book demonstrates how Descartes' attempt to prove the existence of God is foiled by a new Cartesian Circle. (shrink)

Gandhi was a political and social activist rather than a philosopher or thinker. However, the level of morality and purity in his politics was so high that it took politics to the spiritual and philosophical level. The same thing can be said for his social and economic thoughts. Therefore, Gandhi's Swaraj is cultural, political and spiritual because politics was a spiritual ( religious) work for him. The question of Swaraj was not just a political question for him, nor did Swaraj (...) mean for him only the expulsion of the British from India but freedom from slavery mentality as well . Thus, Gandhian Swaraj goes beyond the concept of political sef rule and freedom. Swaraj is one's self rule over body and soul, a comprehensive self control. Swaraj is an equally important question in post independent India too. Swaraj is a vigilance for civil rights, public welfare, constitutionalism and good governance in a politically independent country. It empowers civil society. Hence Swaraj is continuous effort of independence and insistence on truth against arbitrary power of state and thus Swaraj creates and empowers civil society. From this point of view, Locke, Mill, and Rousseau are seen together in his Swarajist thoughts. Therefore, for Gandhi, Swaraj is a continuous process . (shrink)

In recent literature, panpsychism has been defended by appeal to two main arguments: first, an argument from philosophy of mind, according to which panpsychism is the only view which successfully integrates consciousness into the physical world (Strawson 2006; Chalmers 2013); second, an argument from categorical properties, according to which panpsychism offers the only positive account of the categorical or intrinsic nature of physical reality (Seager 2006; Adams 2007; Alter and Nagasawa 2012). Historically, however, panpsychism has also been defended by appeal (...) to a third argument based on considerations about the nature and observability of causation. This argument has not been much discussed in recent times. Here is a concise version from William James: "… the concrete perceptual flux, taken just as it comes, offers in our own activity-situations perfectly comprehensible instances of causal agency … If we took these experiences as the type of what actual causation is, we should have to ascribe to cases of causation outside of our life, to physical cases also, an inwardly experiential nature. In other words, we should have to espouse a so-called “pan-psychic” philosophy" (James 1911: 218). James here suggests that we have direct experience of causation in our own agency. He thereby directly contradicts David Hume, who famously denied that we have any experience of causation. James goes on to claim that if this experience is representative of causation in general, it follows that all causation is mental, and that panpsychism is true. This kind of argument for panpsychism can be called the argument from (experience of) causation. This chapter offers, first, a history of this argument and arguments closely related to it, and second, an analysis of the argument – is it valid, are its premises in any way defensible, and how does it relate to the other, more popular arguments for panpsychism from philosophy of mind and categorical properties? (shrink)

'ā no bhadrāḥ kratavo yantu viśvato ' Let good thoughts come from all around; inspired by this timeless epic of Rigveda. India has presented an excellent model of Multiculturalism to the world. The multiculturalist model of the West, as established by contemporary thinkers like Wilkymalika, is based on the separate political existence of different cultural classes. been made for thousands of years. India has maintained Multiculturalism not only at the socio-cultural level but also at the political level. Through federal structure, (...) universal suffrage, constitutionally guaranteed civil rights, with other constitutional institutions and provisions, multiculturalism is being addressed at the political level for a population of 13 million people .Thus in India , multiculturalism is not only is not only a political tool for diversity but also a socio-political concept. Therefore, Indian multiculturalism presents a comprehensive, effective, and more sustainable model which have to be discussed. (shrink)

This commentary focuses on the importance of auditory object processing for producing and comprehending human language, the relative lack of development of this capability in nonhuman primates, and the consequent need for hominid neurobiological evolution to enhance this capability in making the transition from protosign to protospeech to language.

Multiculturalism is not new concept Multiple cultures existed in Europe and Asia during the mediaeval period. The multicultural societies of Baghdad, Florence, and Venice played an essential role in the spread of knowledge and science. The knowledge transmitted from the House of Wisdom in Baghdad reached the multicultural societies of Venice and Florence. The Multiculturalism of Venice and Florence played an essential role in the emergence of the Renaissance in Europe. Multiculturalism became a crucial political concept in the 20th century (...) with the spread of democracy. In the post-World War II world, when the democratic system of governance spread as a universally accepted system of governance, the question of demand for political rights of multiculturalist groups and adjustment with the existing system arose. There was a massive increase in migration for various reasons, which also gave rise to many other political problems. Multiculturalism and migration got adequate space in Modood's political literature. He presented its socio-political analysis. In discussing the interrelationships between Multiculturalism and liberalism, the question of adjustment of many cultures in relatively less liberal systems provides an alternative perspective to understanding Multiculturalism through migration. -/- . (shrink)

ā no bhadrāḥ kratavo yantu viśvato ' Let good thoughts come from all around; inspired by this timeless epic of Rigveda. India has presented an excellent model of Multiculturalism to the world. The multiculturalist model of the West, as established by contemporary thinkers like Will kymlicka, is based on the separate political existence of different cultural classes. However, India's cultural nationalism has shown how diverse cultures can co-exist with a common socio-political thought over the centuries. Sakas, Huns, Kushans, Turks, Afghan, (...) Iranians, and Mughals all got absorbed in sanatan Indian culture. Not only this , it also gave place to the different cultures to come, and made the model, of coexistence alive. In the name of nationalities like French, Spanish, Portuguese, Polish, and German, Europe got divided into many nation states, but in India Gujarati, Marathi,, Telugu Oriya, Bengali, Punjabi, Assamese, Tamil, Kannada, Malayalam nationalities were not divided into nation states. Instead coexistence has been made for thousands of years. India has maintained multiculturalism not only at the socio-cultural level but also at the political level. Through federal structure, universal suffrage, constitutionally guaranteed civil rights, with other constitutional, institutions and provisions, multiculturalism is being addressed at the political level for population of 13 million people. Thus, in India, multiculturalism is not only a political tool for diversity but also a socio-political concept. Therefore, Indian multiculturalism presents a comprehensive, effective and more sustainable model which have to be discussed. (shrink)