T. Kuhn’s theory of scientific revolutions has repeatedly been the subject of criticism. It is important to note that Kuhn pays very limited attention to the phenomenon of the scientific revolution itself, comparing the revolution either with a religious conversion or with a gestalt switch. Such comparisons, however, are very superficial. This paper outlines a new understanding of the scientific revolution as a result of the resonance of the intellectual trends of the early modern period. It was the quasi-simultaneous action (...) of various factors that led to revolutionary changes in natural philosophy, which, in turn, gave rise to the actual scientific revolution. In addition, the article shows that the Copernican Revolution cannot be described within the model of scientific revolution developed by T. Kuhn. Ptolemy’s theory was mathematically constructed so that it could not make inaccurate predictions of planetary motion, because – as we are now clear – the function characterizing the trajectory of planetary motion was actually represented as a Fourier series. The Copernican revolution was not a Kuhn-type scientific revolution, nor was it caused by the empirical failures of Ptolemaic astronomy. Events unfolded according to a different scheme. Copernicus set out to carry out the principle of the uniform circular motion of the planets more consistently than had been done in Ptolemy’s theory, at the same time presenting to this theory those requirements of an aesthetic and methodological order, which the cognitively fragmented system of Ptolemy, for all its flexibility, could not satisfy and, by the conditions of its creation, could not satisfy. In addition, the article shows that Copernicus, in constructing his heliocentric theory, was essentially seeking answers to the challenges that Alberti’s artificial perspective and Nicholas of Cusa’s theological speculation posed to the visual experience in the sixteenth century. (shrink)

The article is the study of some aspects of the methodology of scientific knowledge that F. Bacon addressed in his treatise “New Organon” (1620) and in other works in one way or another related to his work on the project of the Instauratio Magna Scientiarum. The article focuses on the following three questions: Bacon’s attitude to Aristotle’s legacy, the context of Bacon’s doctrine of idols and the reasons for the English philosopher to choose a fragmented (aphoristic) form of presentation of (...) his ideas in the “New Organon” and in some other works. Based on an analysis of Bacon’s works related to the above project, it was shown that his statements about Aristotle and his philosophy were differentiated depending on whether the corresponding text was intended for printing or served as a working draft. In the latter case, the estimates of Aristotle by Bacon were more stringent. Baconian criticism of Aristotelianism was formed in the context of the development by the English philosopher of the doctrine of the idols of knowledge. The article shows that developing this doctrine, Bacon proceeded from the idea of mass insanity of the human race (insania publica), which has ancient roots and was shared by a number of contemporaries of F. Bacon. At the same time, the latter considered Aristotle as the creator of “a kind of art of insanity (artemque quondam insaniae componere)”. As a cure for “insania universalis”, Bacon proposed a new method (the “new organon”) of cognition, and the presentation of his ideas in the form of separate, but conceptually related aphorisms, as a way of activating the reader’s thought process. (shrink)

The article formulates some aspects concerning the nature and structure of scientific revolutions. As a reference example, the scientific (more precisely, natural-philosophical) revolution of the 16th-17th centuries (SR1) was taken, which in turn became part of the intellectual revolution of the Early Modern period. It is shown that SR1 is not at all monodirectional and not predetermined in its milestones process, when the break with the Aristotelian tradition automatically cleared the way to the new science and philosophy. In reality, there (...) was an intellectual war, the outcome of which was by no means known to any of the opposing sides in advance. In the article eight factors are noted that contributed to the SR1: 1) weakening ideological control on the part of the Church; 2) chaotization and fragmentation of intellectual space; 3) the redundancy of the intellectual resource for the emergence of innovative theories and practices; 4) the presence of intellectual reserve (the legacy of classical Antiquity and the Hellenistic era, as well as the scholastic method); 5) the flow of new information not embedded in traditional world picture and practices; 6) weakening the requirements for the validity of the hypotheses put forward and the rigor of reasoning, declining (delution) the rationality of cognitive activity and behavior; 7) local breakthrough (as seed impulse) in one of the areas of knowledge (heliocentric theory); 8) the possibility of developments a nd tendencies of the proper natural-philosophical revolution to develop in the tideway (in a shell) of innovative concepts, methodologies and practices that have arisen in unscientific spheres (culture, politics, economics, theology, etc.). (shrink)

Although Bastin et al. propose a useful model for thinking about the structure of memory and memory deficits, their distinction between entities and relational encoding is incompatible with data showing that even individual objects – prototypical “entities” – are made up of distinct features which require binding. Thus, “entity” and “relational” brain regions may need to solve fundamentally the same problems.

The relevance of the article is due to the fact that in the modern world, various utopian concepts do not lose their ideological strength, which for more than two centuries have significantly influenced public consciousness and have caused significant transformations in the socio-cultural life of mankind. The connection among social utopias and Christian eschatology has been noticed for a long time, and the thoughts expressed on this occasion by Protopresbyter Alexander Schmemann in articles and diary entries can contribute to a (...) better understanding of deep cognitive processes that largely determine modern social realities. The purpose of the study was based on the analysis of the works of this worthy representative of the philosophy of the Russian diaspora, comparing the traditional religious eschatological "prototype" and later views on the "end of history". These views contributed to the development of utopianism and ideologism in the public mind. The authors focus attention on the antinomical nature of Christian eschatology, in contrast to the various socio-utopian modifications that define social ideals in a field transcendental to everyday human activities. The striving of religious thinking towards the "non-worldly" ideal, as Protopresbyter Alexander Schmemann believed, made it possible to form a Christian's attitude to earthly life, which inevitably required a qualitative transformation corresponding to the notion of the ultimate goal. However, over time, the Christian faith paid less and less attention to the eschatological dimension of human life, which contributed to the formation of new eschatologies seeking their social ideals in the immediate givenness of earthly life and affirming the belief in the possibility of their empirical achievement. The authors of the article come to the conclusion that the most important factor in the formation and development of the "ideological faith" in the public consciousness, the concept of which is defined in the most general terms in the works of Protopresbyter Alexander Schmemann, was the isolation of the dominant ideological structures based on social utopian ideas, from traditional faith grounds. Thus, ideologies ceased to be functional aspects of concrete historical religions, lost their official character and themselves became the foundation for pseudo-religious creativity. (shrink)

I reconstruct Aristotle’s analytical procedure in Prior Analytics I.45 and its metalogical implications. Aristotle’s analysis unfolds three groups of syllogisms: symmetrically analysable, asymmetrically analysable, and non-analysable syllogisms. From the first and the third group could be extracted 27 combinations of the two mutually non-derivable deductive rules. Aristotle’s reduced deductive system in APr. I.7 with the two moods in the first figure (traditionally called Barbara and Celarent) follows this pattern. I demonstrate that the deductive system with Barbara and Celarent is just (...) one of 27 possible complete deductive systems with the two mutually non-derivable syllogistic rules. On top of that, given the fact that there are two combinations of mutually non-derivable conversion rules, I conclude that Prior Analytics hides in itself 54 complete deductive systems with a minimal number of mutually non-derivable rules. Finally, it is commented what might be the role of analysis; to what extent Aristotle could be aware of possibilities presented here; why he still prefers only one deductive system to many others with the same deductive power. (shrink)

David Earl Over is a leading cognitive scientist and, with his firm grounding in philosophical logic, he also exerts a powerful influence on the psychology of reasoning. He is responsible for not only a large body of empirical work and accompanying theory, but for advancing a major shift in thinking about reasoning, commonly known as the 'new paradigm' in the psychology of human reasoning. Over's signature mix of philosophical logic and experimental psychology has inspired generations of researchers, psychologists, and philosophers (...) alike over more than a quarter of a century. The chapters in this volume, written by a leading group of contributors including a number who helped shape the psychology of reasoning as we know it today, each take their starting point from the key themes of Over's ground-breaking work. The essays in this collection explore a wide range of central topics--such as rationality, bias, dual processes, and dual systems--as well as contemporary psychological and philosophical theories of conditionals. It concludes with an engaging new chapter, authored by David Over himself, which details and analyses the new paradigm psychology of reasoning. This book is therefore important reading for scholars, researchers, and advanced students in psychology, philosophy, and the cognitive sciences, including those who are not familiar with Over's thought already. (shrink)

The most enigmatic feature of polytene chromosomes is their banding pattern, the genetic organization of which has been a very attractive puzzle for many years. Recent genome‐wide protein mapping efforts have produced a wealth of data for the chromosome proteins of Drosophila cells. Based on their specific protein composition, the chromosomes comprise two types of bands, as well as interbands. These differ in terms of time of replication and specific types of proteins. The interbands are characterized by their association with (...) “active” chromatin proteins, nucleosome remodeling, and origin recognition complexes, and so they have three functions: acting as binding sites for RNA pol II, initiation of replication and nucleosome remodeling of short fragments of DNA. The borders and organization of the same band and interband regions are largely identical, irrespective of the cell type studied. This demonstrates that the banding pattern is a universal principle of the organization of interphase polytene and non‐polytene chromosomes.Editor's suggested further reading in BioEssaysCaught in the act: Rapid, symbiont‐driven evolution AbstractFunction and evolution of sex determination mechanisms, genes and pathways in insects Abstract. (shrink)

We focus here on the intercalary heterochromatin (IH) of Drosophila melanogaster and, in particular, its molecular properties. In the polytene chromosomes of Drosophila, IH is represented by a reproducible set of dense bands scattered along the euchromatic arms. IH contains mainly unique DNA sequences, and shares certain features with other heterochromatin types such as pericentric, telomeric, and PEV‐induced heterochromatin, the inactive mammalian X‐chromosome and the heterochromatized male chromosome set in coccids. These features are transcriptional silencing, chromatin compactness, late DNA replication, (...) underrreplication or elimination in somatic cells, and formation of the heterochromatin state in early embryogenesis. Post‐translational modification of histones and the specific nonhistone protein complexes are shown to participate in the establishment and maintenance of silencing for all heterochromatin types. Many IH regions contain binding sites for HP1 and/or Pc‐G proteins and all the regions are sites of heterochromatin‐associated SuUR protein. Some IH regions are known to contain homeotic genes. Summarizing these data, we suggest that IH regions comprise stable inactivated genes, whose silencing is developmentally programmed. BioEssays 25:1040–1051, 2003. © 2003 Wiley Periodicals, Inc. (shrink)

This paper reports a study of the main key components of influence on the stability of transportation enterprises in the market. A model for evaluating the effectiveness of innovation activity in the transport industry, which takes into account indicators of expenditures on innovations, has been built. It makes it possible to determine the effectiveness of introduced innovations, which indicates the appropriate level of innovation potential and the ways that the enterprise must take to increase it. The main directions of innovative (...) development of transportation enterprises were investigated. The assessment of the economic stability of transportation enterprises in the market has established that the current state of development of enterprises is characterized by a weak level of their innovative activity. A systematic approach to the introduction of innovative technologies by a transportation enterprise in the market has been devised. This approach makes it possible to determine the required level of enterprise stability and to form a relationship between the level of innovative technologies and their stages of implementation under conditions of environmental variability. This makes it possible to increase competitive advantages, improve the efficiency of production and economic activity of enterprises. The practical implementation of the proposed model for evaluating the effectiveness of innovation activity in the transport industry has been carried out, which made it possible to allocate the most important indicators of innovation activity for the enterprise. These include specific efficiency of innovation; unit costs of innovation; innovative potential of the enterprise (defined as the proportion of own innovative developments). According to the study results, it is determined that the specific efficiency of innovations (SEI) exerts the greatest influence, which, with an increase by 1 %, provides an increase in financial stability by 1.48 %. (shrink)

This study aimed to understand the expressions of fear in the journeys of health professionals who worked in the confrontation of coronavirus disease 2019 (COVID‐19), in the city of Manaus, in the Brazilian Western Amazon. This is an exploratory qualitative study that adopts interpretive description as a method to generate informed knowledge responsive to the needs of the practice. We included 56 participants, comprising 23 health managers and 33 health workers (middle and higher level) of different professional categories. The results (...) revealed three circles of experience: (1) knowledge and professional experience in dealing with the disease (unknown–known–experienced); (2) the growing proximity to death and loss (predicted–witnessed–suffered); and (3) the involvement and proximity to whatever affects the individual, their emotions, and personal transformations in the face of the threat (the collective, the neighbor, and oneself). Our results suggest that health professionals who worked during the COVID‐19 pandemic in Manaus experienced insecurity, dread, and fear, illustrating the complexity of developing their activities in the front line of care and management during the different phases of the pandemic. A contribution of the study is precisely that of capturing this complexity, which suggests the impossibility of analyzing fear only in its simple manifestation, or in each circle of experience. (shrink)

Species, or ‘the Species Problem’, is a topic in science, in the philosophy of science, and in general philosophy. There is not one, but many, species problems, and these are dealt with in this volume. Species are often thought of as units of biology, to be used in ecology, conservation, classification, and theory. The chapters in this book present opposing views on the current philosophical and conceptual issues of the Species Problem in biology. -/- Divided into four sections Theories and (...) Concepts, Practice and Methods, Ranks, Trees and Names, and Metaphysics and Epistemologies, the book is authored by systematists, philosophers, historians and working biologists, many leaders in their fields. Topics include Essentialism and individuals, speciation modes, theory and the species rank, nomenclature and diagnosis, scale of species, and ecology, conservation, and species. -/- Species Problems and Beyond aims to clarify the contemporary issues of the Species Problem. It is ideal for use in upper-level seminars and courses in Evolutionary Biology, Philosophy of Science, Philosophy of Biology, Systematics and Taxonomy, and Phylogenetics/Cladistics, and for any scholar in these fields. (shrink)

Stress is one of the most powerful experiences to influence health and disease. Through epigenetic mechanisms, stress may generate a footprint that propagates to subsequent generations. Programming by prenatal stress or adverse experience in parents, grandparents, or earlier generations may thus be a critical determinant of lifetime health trajectories. Changes in regulation of microRNAs (miRNAs) by stress may enhance the vulnerability to certain pathogenic factors. This review explores the hypothesis that miRNAs represent stress‐responsive elements in epigenetic regulation that are potentially (...) heritable. Recent findings suggest that miRNAs are key players linking adverse early environments or ancestral stress with disease risk, thus they represent useful predictive disease biomarkers. Since miRNA signatures of disease are potentially heritable, big data management platforms will be vital to harness multi‐generational information and capture succinct yet potent biomarkers capable of directing preventative treatments. This feature would offer a unique window of opportunity to advance personalized medicine. (shrink)

Putnam's model theoretic argument against metaphysical realism can be reconstructed as valid, with premises acceptable to the realist. There is no illegitimate assumption that the causal theory of reference is false.

While some argue that the only way to make a place for Philosophy for Children in today's strict, standardised classroom is to measure its efficacy in promoting reasoning, we believe that this must be avoided in order to safeguard what is truly unique in P4C dialogue. When P4C acquiesces to the very same quantitative measures that define the rest of learning, then the philosophical dimension drops out and P4C becomes yet another progressive curriculum and pedagogy for enhancing argumentation skills that (...) can easily be appropriated by any content area. What we want to offer in this article is a reevaluation of P4C that remains faithful to a radical kernel that we find when we do philosophy with children and young adults. To theorise the potential for P4C, we draw heavily on Agamben's work, and in particular his reflections on speech and infancy. We propose that the redemption of P4C necessitates a shift from a community of inquiry to a community of infancy. Such a community is not a community that operates according to predefined rules or standardised assessment protocols but rather is an inoperative community that is defined by letting ends idle. On our account, a community of infancy is an example of dialogic studious play that is neither ritual nor just play, thus avoiding the extreme polarities of the ritualised classrooms of high-stakes testing and the ‘ludic’ postmodern classroom of free play. What is at stake here is to preserve the last vestige of freedom within the school. (shrink)

Bradley has argued that a truth-conditional semantics for conditionals is incompatible with an allegedly very weak and intuitively compelling constraint on the interpretation of conditionals. I argue that the example Bradley offers to motivate this constraint can be explained along pragmatic lines that are compatible with the correctness of at least one popular truth-conditional semantics for conditionals.

The article refutes the widespread view that Dostoevsky's Christian beliefs were strictly Orthodox. It is proved that Dostoevsky's religious and philosophical searches' central tendency is the criticism of historical, ecclesiastical Christianity as a false, distorted form of the teaching of Jesus Christ and the desire to restore this teaching in its original purity. Modern researchers of the history of early Christianity find more and more arguments in favor of the fact that the actual teaching of Jesus Christ is contained in (...) that religious movement, which the church called the Gnostic heresy. The exact philosophical expression of the teaching of Christ was received in the later works of J.G. Fichte, whose ideas had a strong influence on the Russian writer. Like Fichte, Dostoevsky understands Christ as the first person who showed the possibility of revealing God in himself and gaining divine omnipotence and eternal life directly in earthly reality. In this sense, every person can become like Christ. Dostoevsky's main characters walk the path of Christ and show how difficult this path is. The article shows that Dostoevsky used in his work not only the philosophical version of true Christianity developed by German philosophy, but also the key motives of the Gnostic myth, primarily the idea that our world, filled with evil and suffering, is created not by the supreme, good God-Father, but by the evil Demiurge, the Devil. (shrink)

The analysis of the play "The Seagull" undertaken in the article is based on an unusual assumption. Chekhov's phrase is known that "after writing a story, you should cross out its beginning and end." What if we apply this "formula" to the dramatic works of Anton Pavlovich and assume that when finishing the plays, Chekhov "left out some part of the text"? The analysis of the "Seagull" is performed directly by the classic tool of directors – the method of effective (...) analysis. The work involved a wide range of facts about the social and everyday realities of the Russian Empire of the late XIX - early XX century. The choice of the play "The Seagull" is due to two reasons. Firstly, it is one of Chekhov's most famous and popular dramas. Interest in it has not waned for many decades, neither the audience nor the directors. Secondly, it is believed that the "Seagull" is read inside and out, and working with it is a challenge for the researcher. The analysis of "The Seagull" allows us to state that Chekhov's formula about "crossing out the beginning and the end" of the story is also applicable to his plays. Moreover, this "crossing out" is made taking into account the principles of classical drama. As a result, the reader is faced with the fact that the "Seagull" can be read in at least two – almost opposite in meaning – ways. The results obtained during the analysis, firstly, give grounds to assume that the case of the "Seagull" is not an isolated one, and Chekhov resorted to similar techniques in his other dramas. Secondly, to conclude that the "dramatic mechanism" of The Seagull is not just an attribute of the author's voice, but actually the path of evolution of classical drama proposed by Chekhov. (shrink)

Bradley has argued that a truth-conditional semantics for conditionals is incompatible with an allegedly very weak and intuitively compelling constraint on the interpretation of conditionals. I argue that the example Bradley offers to motivate this constraint can be explained along pragmatic lines that are compatible with the correctness of at least one popular truth-conditional semantics for conditionals.

As early as 1962, Jürgen Habermas was convinced that Karl Marx’s theoretical attempt to ‘turn Hegel the right side up’ had resulted in a one-sided embrace of revolution and a perilous rejection of legality and rights. Habermas would restate these remarks thirty years later in Between Facts and Norms, noting that the collapse of state socialism, with its characteristic disdain for legality and rights, culminated in the discrediting of revolutionary Marxism. This article revisits Habermas’s theoretical dichotomy between revolution and legality (...) in view of his ambivalent relationship to ‘Marx’s spectre’ and shows its significance for Habermas’s ongoing debate with Wolfgang Streeck concerning the tension between democracy and capitalism. Using textual evidence from Marx’s neglected journalistic writings before, during, and after the 1848 revolutions, the article offers a competing perspective of Marx’s views on legality and rights at a time when their respective fates were critically at stake. A careful reconsideration of Marx’s reflections and a confrontation with his spectre offers Habermas fruitful resources for responding to Streeck’s critique and for reviving the project of ‘radical reformism’ at a time when the liberal constitutional order finds itself under attack. (shrink)