The author?s approach is based on three premises: 1. that Gajo Petrovic?s Praxis was an outstanding phenomenon in Croatian, Yugoslav and European culture, a challenge of freedom in a repressive society; 2. that there has never been such a thing as "Praxis group", "philosophers of practice" or "Praxis philosophers" with a unified philosophical and socio-theoretical orientation; and 3. that political and ideological attacks on Praxis were part of the repressive system that targeted every instance of cultural and scientific dissent. The (...) political leadership of Tito?s regime, its ideological and propaganda apparatus systematically disseminated allegations, denunciations and accusations against Praxis and Gajo Petrovic. The same style has survived through radical historical changes from the appearance of Praxis until today. The attackers have often been the same persons, with the difference that in earlier times they denounced Praxis and Gajo Petrovic as enemies of "socialism" and the "socialist self-management system", and in the changed political fashion as "servants" of Tito?s authoritarian rule. The fate of Praxis in the former regime has been triumphantly interpreted as a "family quarrel". This paper attempts a sociological analysis of the political destiny of Praxis. The analysis is essentially determined not by old and new political and ideological questionings of Praxis, but by Gajo Petrovic?s fundamental belief that there is no freedom without the human or humanity without freedom.. Osnovu autorovog pristupa cine tri stava: 1. da je Praxis Gaje Petrovica bio izuzetna pojava u hrvatskoj, jugoslovenskoj i evropskoj kulturi, izazov slobode u drustvu represije; 2. da ne postoji tako nesto kao "praxis-grupa", "filozofi prakse" ili "praxis filozofi" koji bi imali jedinstvenu filozofsku ili drustveno-teorijsku orijentaciju; 3. da su politicka i ideoloska osporavanja Praxisa bila deo represivnog sistema kojem je bilo podvrgnuto svako neistomisljenistvo u kulturi i nauci. Politicki vrh Titovog rezima, njegov ideoloski i propagandni aparat sistematski su sirili insinuacije, denuncijacije i optuzbe o Praxisu i Gaji Petrovicu, da bi taj manir u bitno promenjenim istorijskim okolnostima, trajao od pojave Praxisa do danasnjeg dana. Cesto su i akteri napada bile iste osobe, samo sto su nekada osporavali Praxis i Gaju Petrovica kao neprijatelje "socijalizma" i "sistema socijalistickog samoupravljanja", a u promenjenoj politickoj modi kao "sluge" Titove autoritarne vladavine. Sudbinu Praxisa u prethodnom rezimu slavodobitno su tumacili kao "obracun u obitelji". Rad je pokusaj socioloske analize politicke sudbine Praxisa, koju ce bitno odrediti temeljno uverenje Gaje Petrovica da nema slobode bez coveka ni ljudskosti bez slobode, a ne stara i nova politicka i ideoloska osporavanja Praxisa.. (shrink)

En tant que communaut? ethnique et groupe social d?favoris?, les Roms se heurtent quotidiennement aux probl?mes relatifs r l?obtention de papiers d?identit? ou autres documents, difficult? qui les prive de leur?galit? devant l?ensemble des citoyens, et les rend m?me inexistants. L?objet de cet te recherche porte sur les d?marches et probl?mes rencontr?s par les demandeurs en vue d?obtenir les documents suivants: a) num?ro d?immatriculation; b) extrait d?acte de naissance, dedans, de mariage; c) certificat de nationalit?; d) d?claration de s?jour et (...) de lieu de r?sidence; e) carte d?identit? et carte de travail, alors que les groupes vis?s par la recherche sont: employ?s et responsables d?offices d??tat civil; demandeurs, interm?diaires avec autorisations, militants roms et leurs associations, commissaires pour les r?fugi?s et personnes d?plac?es, fonctionnaires de certaines communes et secr?taires des communes, repr?sentants de MUP. Nous avons analys? le travail et les difficult?s de travail de certains organismes, ainsi que les probl?mes rencontr?s par les demandeurs et les interm?diaires avec autorisations en vue de se voir d? livrer des documents personnels ou lors des proc?dures d?obtention de documents personnels. En dernier lieu, nos recommandations concernent l?organisation et la coordination des organismes d??tat civil, une meilleure information s?adressant aux demandeurs, et contiennent le concept d?une am?lioration syst?matique de cet?tat de choses visant r ce que les roms de viennent des citoyens?gaux.. Kao deprivirana etnicka zajednica i socijalna grupa Romi se suocavaju u svakodnevnom zivotu sa problemima pribavljanja osnovnih licnih dokumenata, bez kojih su ne samo neravnopravni, nego cesto i neegzistentni gradjani. Predmet istrazivanja su bili postupci i problemi u sticanju sledecih dokumenata: a) jedinstveni maticni broj gradjana; b) izvodi iz maticnih knjiga rodjenih, umrlih, vencanih; c) uverenja o drzavljanstvu; d) prijava boravka i prebivalista e) licne karte i rad ne knjizice, a osnovne ciljne grupe istrazivanja bili su: sluzbenici i rukovodioci izmestenih maticnih ureda; neposredni podnosioci zahteva za izdavanje dokumenata; posrednici sa ovlastenjima ; romski aktivisti i udruzenja, javni zastupnici, poverenici za izbegli ce i raseljena lica; nacelnici pojedinih opstinskih sluzbi i sekretari opstina, predstavnici MUP-a. Analiziran je rad i poteskoce u radu maticnih i drugih sluzbi, problemi neposrednih podnosilaca zahteva za izdavanje nekog od licnih dokumenata i, posrednici sa ovlascenjima. Na kraju je u preporukama o organizaciji i koordinaciji rada maticnih sluzbi, preporukama za bolje informisanje Roma, podnosilaca zahteva i preporukama u korist podnosilaca zahteva sadrzan koncept sistematskog poboljsanja stanja, cime bi se Romima omogucilo da budu istinski ravnopravni gradjani Srbije. (shrink)

Autor analizira stavove intelektualaca s podrucja bivse Jugoslavije, okupljenih oko casopisa Praxis, prema nacionalizmu, kao i kritike koje su im upucivali nacionalisti, pre svega iz Hrvatske i Srbije. Analiza obuhvata period od pojave Praxisa do prve decenije dvadeset prvog veka.

On the basis of his own previous research the author examines views of Europe held by the Serbian political and cultural elite in the late 20th and early 21st century. Unable to meet the challenges of the historical moment, this elite has brought Serbia into open conflict with its closest neighbors and exposed its citizens to international sanctions. War-mongering propaganda of the major state-controlled media was developing feelings of xenophobia and frustration among citizens. The collusion between authoritarian government and war (...) profiteers was systematically destroying the lives of Serbian citizens, bringing them to the brink of material impoverishment and spiritual misery. The process of dissolution of the common Yugoslav state is coming to its end in the first decade of this century. Just as it lacked wisdom political will or strength to prevent armed conflicts and crimes, the Serbian elite today is unable to condemn war crimes, to face disastrous consequences of its own policies, and to help Serbian citizens find their way to prosperity. (shrink)

BackgroundInnovations in technology have contributed to rapid changes in the way that modern biomedical research is carried out. Researchers are increasingly required to endorse adaptive and flexible approaches to accommodate these innovations and comply with ethical, legal and regulatory requirements. This paper explores how Dynamic Consent may provide solutions to address challenges encountered when researchers invite individuals to participate in research and follow them up over time in a continuously changing environment.MethodsAn interdisciplinary workshop jointly organised by the University of Oxford (...) and the COST Action CHIP ME gathered clinicians, researchers, ethicists, lawyers, research participants and patient representatives to discuss experiences of using Dynamic Consent, and how such use may facilitate the conduct of specific research tasks. The data collected during the workshop were analysed using a content analysis approach.ResultsDynamic Consent can provide practical, sustainable and future-proof solutions to challenges related to participant recruitment, the attainment of informed consent, participant retention and consent management, and may bring economic efficiencies.ConclusionsDynamic Consent offers opportunities for ongoing communication between researchers and research participants that can positively impact research. Dynamic Consent supports inter-sector, cross-border approaches and large scale data-sharing. Whilst it is relatively easy to set up and maintain, its implementation will require that researchers re-consider their relationship with research participants and adopt new procedures. (shrink)

An increasing body of evidence indicates that the response to genotoxic agents such as radiation or drugs is a group phenomenon, rather than the summed response of individual independent cells to injury. Thus, a complex contagion-like response may spread beyond the initial impact of an agent to enlarge its effect. This indirect effect, termed “Bystander Effect,” is multifaceted and may play a significant role in the therapy of tumors and in carcinogenesis. A better understanding of this phenomenon is needed in (...) order to modulate treatment protocols to therapeutic advantage and to provide more rational guidelines for the evaluation of environmental hazards. BioEssays 22:286–290, 2000. © 2000 John Wiley & Sons, Inc. (shrink)

Personalized medicine aims to tailor disease prevention, diagnosis, and treatment to individuals on the basis of their genes, lifestyle and environments. Patient and interest organizations may potentially play an important role in the realization of PM. This paper investigates the views and perspectives on PM of a variety of PIOs. Semi-structured telephone interviews were conducted among leading representatives of 13 PIOs located in Europe and North-America. The data collected were analysed using a conventional content analysis approach. The PIO representatives supported (...) the realization of PM but feared that many financial, structural and organizational challenges may delay its realization. They encouraged strategies to modernize drug licencing mechanisms, develop research and data sharing infrastructures, and educate patients and health care professionals in PM. Notably, they emphasized the importance of developing PM in an equitable way and taking into consideration the patients’ needs, values and personal situation. Despite varying levels of awareness regarding PM, the PIO representatives expressed willingness to engage in the PM agenda and recommended that PIOs work closely with policy-makers to design PM in a way that truly addresses the needs and concerns of patients. PIOs have the potential to become central drivers of the PM agenda. Collaborations should be further developed between PIOs, researchers, drug developers and health care authorities. (shrink)

Rad ukazuje na kljucne momente razvoja teorije aktera-mreze kroz nekoliko najznacajnih dela Bruna Latura. Uocavaju se promene pocetne pozicije autora u odnosu na dela kasnijeg datuma nastanka. Teorija aktera-mreze je prikazana kroz niz?neuralgicnih? tacaka koje se u njoj mogu uociti. Na samom kraju rada su razmatrana resenja koje teorija aktera-mreze nudi za odredjeni broj fundamentalnih problema sociologije, koje je definisao Latur.

There is an emerging awareness of the possibility of conflicts of interest in the practice of medicine in Croatia. The paper examines areas within the medical profession where conflicts of interest can and have occurred, probably not only in Croatia. Particularly addressed are situations when a doctor may have dual obligations and how independent ethics committees can help in decreasing the influence of a conflict of interest. The paper also presents extracts from the Croatian Code of Ethics for the medical (...) profession that address problems of conflict of interest. (shrink)

The Helsinki Declaration is the ‘gold standard’ — a directive, not a law, on how to conduct controlled studies in humans in conformity with ethical principles. In spite of many discussions about their unsuitability some articles have remained unchanged in the most recent (sixth) revision of the Declaration. The demand to use “the best treatment” excludes use of placebo in the control group and presents an obstacle to the scientific evaluation of a number of drugs and treatments in general. The (...) use of placebo is justified whenever its use does not cause irreversible damage or considerable suffering to the well informed patient. It must be, is, and will be used in the controlled clinical trials of treatments of a great number of diseases especially those which have a tendency to spontaneous improvement, even healing, or have a pronounced psychological component. (shrink)

The philosopher Jorge J. E. Gracia engages fifteen prominent scholars on race, ethnicity, nationality, and Hispanic/Latino identity in the United States. Their discussion joins two distinct traditions: the philosophy of race begun by African Americans in the nineteenth century, and the search for an understanding of identity initiated by Latin American philosophers in the sixteenth century. Participants include Linda M. Alcoff, K. Anthony Appiah, Richard J. Bernstein, Lawrence Blum, Robert Gooding-Williams, Eduardo Mendieta, and Lucius T. Outlaw Jr., and their dialogue (...) reflects the analytic, Aristotelian, Continental, literary, Marxist, and pragmatic schools of thought. These intellectuals start with the philosophy of Hispanics/Latinos in the United States and then move to the philosophy of African Americans and Anglo Americans in the United States and the philosophy of Latin Americans in Latin America. Gracia and his interlocutors debate the nature of race and ethnicity and their relation to nationality, linguistic rights, matters of identity, and Affirmative Action, binding the concepts of race and ethnicity together in ways that open new paths of inquiry. Gracia's Familial-Historical View of ethnic and Hispanic/Latino identity operates at the center of each of these discussions, providing vivid access to the philosopher's provocative arguments while adding unique depth to issues that each of us struggles to understand. (shrink)

El historiador William Hickling Prescott (Salem, 1796-Boston, 1859) publicó la famosa History of the Conquest of México en tres gruesos tomos en 1843. La obra tuvo un impacto inmediato, en parte por la reputación de Prescott como un historiador serio, y en parte por una prosa que resultaba atractiva para un público ya acostumbrado a la lectura, especialmente de novelas. Además, entre 1819, la fecha del acuerdo Adams-Onis que fijaba los límites entre Estados Unidos y México, y la guerra entre (...) ambos países en 1846-1848, surgió con fuerza el interés por los asuntos hispanoamericanos. La obra de Prescott apareció en ese contexto, y además proporcionó un modelo de estudios históricos basados en fuentes documentales. No existía un estudio equivalente en extensión y profundidad, publicado en inglés, de modo que se instaló rápidamente como una obra fundamental de historiografía, que impacta hasta el día de hoy. (shrink)