Whole eye transplantation (WET) remains experimental. Long presumed impossible, recent scientific advances regarding WET suggest that it may become a clinical reality. However, the ethical implications of WET as an experimental therapeutic strategy remain largely unexplored. This article evaluates the ethical considerations surrounding WET as an emerging experimental treatment for vision loss. A thorough review of published literature pertaining to WET was performed; ethical issues were identified during review of the articles.

Evidence suggests that humans might have neurological specializations for music processing, but a compelling adaptationist account of music and dance is lacking. The sexual selection hypothesis cannot easily account for the widespread performance of music and dance in groups (especially synchronized performances), and the social bonding hypothesis has severe theoretical difficulties. Humans are unique among the primates in their ability to form cooperative alliances between groups in the absence of consanguineal ties. We propose that this unique form of social organization (...) is predicated on music and dance. Music and dance may have evolved as a coalition signaling system that could, among other things, credibly communicate coalition quality, thus permitting meaningful cooperative relationships between groups. This capability may have evolved from coordinated territorial defense signals that are common in many social species, including chimpanzees. We present a study in which manipulation of music synchrony significantly altered subjects’ perceptions of music quality, and in which subjects’ perceptions of music quality were correlated with their perceptions of coalition quality, supporting our hypothesis. Our hypothesis also has implications for the evolution of psychological mechanisms underlying cultural production in other domains such as food preparation, clothing and body decoration, storytelling and ritual, and tools and other artifacts. (shrink)

His authority is always grounded in the very authority he deposes, with the result that his voice is little more than a theatrical performance that unwittingly re-enacts the rhetorical maneuvers of deposed father figures.

What do we learn about language from reading Wittgenstein'sPhilosophical Investigations? This question gains urgency from Wittgenstein's alleged animus against philosophical theorizing and his indirectness. Section 1 argues that Wittgenstein's goal is to prevent philosophical questioning about the foundations of language from the beginning. This conception of his aim is not in tension with Wittgenstein's use of the notion of community; community interpretations of his views betray a misguided commitment to the coherence of the idea that language might need grounding. Wittgenstein's (...) goal is not to enjoin us not to step outside of language-games, but to show that we have insufficiently clear grasp of the terms we try to use to express the limits of intelligibility. Section 2 suggests that appreciating Wittgenstein's moral concerning the relation between language and philosophizing about it involves allowing him to teach us how to read his book. What makes readingPhilosophical Investigations possible is openness to learning how not to forget our lives in language. (shrink)

To begin with, there is a conceptual necessity implied in the very concept of cause itself, and in all concepts that have a causal element; and this definitional "must," far from being conventional or arbitrary, reflects the natural necessity of those physical systems which in fact constitute the nature of our universe. The conceptual necessity of the concept of cause can be pointed up in the following way. Assume that we have good reason for saying at to that f, g, (...) h, and i are jointly sufficient to E and hence C of E. What would we say at t1 if f, g, h, and i occurred but not E? We would clearly not say then, or ever, that while ordinarily these conditions are jointly sufficient for E, this time they were not; rather we would say that somehow we were mistaken in thinking that f, g, h, and i at t1 were identical with f, g, h, and i at t0. We might have been mistaken in either of two ways. We might have mis-identified one of the conditions at t1, erroneously thinking, say, that p was an f; or one or more of the conditions might have had its nature altered, losing some capacity or power it once had. In either case, we would withdraw the claim at t1 that C was the cause of E. Since we would withdraw the use of C at t1 and would never admit that f, g, h, and i at any t, if genuine instances of f, g, h, and i, would not produce E, we are clearly using C in such a way that actually producing E is part of its meaning. On the assumption that the conditions are genuinely the same, it follows, so to speak, from the principle of identity that they must produce the same effect. (shrink)

In my field, animal developmental biology, and in what could be regarded as its “deep time derivative,” the evolutionary biology of the animal body plan, there exist two kinds of experimentally supported causal explanation. These can be described as “rooted” and “unrooted.” Rooted causal explanation provides logical links to and from the genomic regulatory code, extending right into the genomic sequences that control regulatory gene expression. The genomic regulatory code ultimately determines the developmental process in a direct way, since subsequent (...) developmental events all depend directly and specifically on what regulatory genes are being expressed and where in the developing organism they are being expressed.. (shrink)

Implicit in the scottish tradition is a metaphilosophy of commonsense which deserves as much attention as that recently given to scottish presentative realism and agent causality. The author articulates this metaphilosophy by (a) sketching a systematic metaphilosophy of commonsense, (b) considering to what extent thomas reid fits this pattern, And (c) deciding to what extent asa mahan, One of the ablest of the american realists, Fits it. The result is a characterization of a coherent scottish metaphilosophy still worthy of consideration. (...) He also explores the question whether the metaphilosophy that emerges from (b) and (c) is part of an ongoing tradition. It has been suggested that there are important similarities between the scottish view and g e moore's concept of analysis. While he agrees that there are analogies he stresses the disanalogies as more enlightening about the nature of both. (shrink)

There are a standard number of replies to the riddle of induction, none of which has gained ascendency. It seems that a new approach is needed that concedes less to the Humean dialectic. Humeans, both traditional and contemporary, unwittingly play on the ambiguity of the phrase "change in the course of nature," and that is why `C· ∼ E' appears to be self-consistent, though in fact it is not. I provide an analysis of 'cause' and 'natural necessity' which gives inductive (...) inference that internal warrant we assume it to have in ordinary and scientific thinking and rebut in advance contemporary Humean objections based on the erroneous assumption that 'x is necessary' and 'x is a priori' are materially equivalent. (shrink)

HAMILTON WORRIED THAT THERE WERE REPRESENTATIVE ELEMENTS\nIN REID'S EPISTEMOLOGY, WHILE J S MILL FLATLY CHARACTERIZED\nTHE SCOT AS A REPRESENTATIVE REALIST. I ARGUE THAT HAMILTON\nAND MILL WERE MISTAKEN AND THAT THEIR MISTAKES AROSE FROM\nAN INSUFFICIENT UNDERSTANDING AND APPRECIATION OF THE\nNATIVISTIC ELEMENTS OF THE UNDERSTANDING INTRODUCED BY\nREID; AND TO INSUFFICIENT AWARENESS OF REID'S\nCHARACTERIZATION OF PERCEPTION AS ACTIVE IN CONTRAST TO\nBRITISH EMPIRICIST RELIANCE ON A PASSIVELY GIVEN EPISTEMIC\nBASE. REID REJECTED EVERY VARIETY OF THE "MESSENGER"\nTHEORY.

Using a general model of corruption that explains and accounts for corruption across different corporate and professional activities, the paper will examine how certain practices in the media, especially in areas where journalism, advertising and public relations regularly intersect and converge, can be construed as instances of corruption. By applying this general model of corruption the paper will then offer a taxonomy of media corruption by identifying most if not all the major types of media corruption. It will be argued (...) that such corruption is regular and systematic. (shrink)

The use of negative probabilities is discussed for certain problems in which a stochastic process approach is indicated. An extension of probability theory to include signed (negative and positive) probabilities is outlined and both philosophical and axiomatic examinations of negative probabilities are presented. Finally, a class of applications illustrates the use and implications of signed probability theory.

IN the recent past there has been a resurgence of interest in the work of Thomas Reid; several new editions of his work have appeared as well as a series of articles concerning various aspects of his systematic philosophy. Interest has generalized to the whole Scottish tradition, including numerous figures in the history of American philosophy who were deeply influenced by Reid and Dugald Stewart. In addition, several recent and contemporary philosophers have used Reid's epistemic views as a point of (...) departure in developing their own adverbial theories of sensing and appearing. Others have used Reid's theory of agency in formulating their own views on freedom and responsibility. (shrink)

At Epistles 2.2.87–9 Horace introduces an argument against writing poetry based on the unpleasant mutual admiration required in poetic society with an anecdote about an orator and a jurisconsult: †frater erat Romae† consulti rhetor, ut alter alterius sermone meros audiret honores, Gracchus ut hic illi, foret huic ut Mucius ille.

At Epistles 2.2.87–9 Horace introduces an argument against writing poetry based on the unpleasant mutual admiration required in poetic society with an anecdote about an orator and a jurisconsult: †frater erat Romae† consulti rhetor, ut alter alterius sermone meros audiret honores, Gracchus ut hic illi, foret huic ut Mucius ille.