This manuscript reports on a landmark symposium on the ethical, legal and technical challenges of xenotransplantation in the UK. King’s College London, with endorsement from the British Transplantation Society (BTS), and the European Society of Organ Transplantation (ESOT), brought together a group of experts in xenotransplantation science, ethics and law to discuss the ethical, regulatory and technical challenges surrounding translating xenotransplantation into the clinical setting. The symposium was the first of its kind in the UK for 20 years. This (...) paper summarises the content of the expert lectures showcasing the progress which has been made in xenotransplantation including—the history of xenotransplantation, advances in gene edited animals and progress towards clinical xenotransplantation. We then set out the ethical and legal issues still to be resolved. Finally, we report the themes of the roundtable discussion highlighting areas of consensus and controversy. While the detail of the legal discussion was directed towards the UK, the principles and summary reported here are intended to be applicable to any jurisdiction seeking to implement clinical xenotransplantation. (shrink)

A recent issue of Time magazine (March 29, 1999) was devoted to the twenty greatest "thinkers" of the twentieth century -- scientists, inventors, and engineers. There is one interesting omission: there are no cognitive psychologists or cognitive scientists. (Cognitive science is an amalgam of cognitive, neuro, and developmental psychology, artificial intelligence, philosophy, linguistics, biology, and anthropology.) Freud is there, to be sure. But, while he was very influential, it is not even clear that he was a scientist, let alone (...) a cognitive scientist. There are those who regard Freud as somewhere between incompetent and a charlatan (see Glymour, 1988). In any case, though Freud's positive proposal for the mind's architecture -- namely, that it contains the unconscious -- seems correct as far as it goes, it does appear that all the details are wrong. For example: (1) there is a lot more to the mind than the mere unconscious; (2) it is doubtful that there is an id, ego, and superego; (3) most dreams may very likely be meaningless; and (4) human motivation, even unconscious motivation, is about a lot more than sex. In the end, because he was most interested in certain kinds of human mental malfunctioning, Freud is probably best thought of as a physician, a proponent and early explorer of human mental health; he was not an experimental cognitive psychologist. (shrink)

Under the Superstition Mountains in central Arizona toil those who would rob humankind of its humanity. These gray, soulless monsters methodically tear away at our meaning, our subjectivity, our essence as transcendent beings. With each advance, they steal our freedom and dignity. Who are these denizens of darkness, these usurpers of all that is good and holy? None other than humanity’s arch-foe: The Cognitive Scientists -- AI researchers, fallen philosophers, psychologists, and other benighted lovers of computers. Unless they are (...) stopped, humanity -- you and I -- will soon be nothing but numbers and algorithms locked away on magnetic tape. (shrink)

Name der Zeitschrift: Jahrbuch für Wissenschaft und Ethik Jahrgang: 20 Heft: 1 Seiten: 293-302.

Name der Zeitschrift: Jahrbuch für Wissenschaft und Ethik Jahrgang: 20 Heft: 1 Seiten: 237-240.

In this book, Robert Caper provides the reader with an introduction to psychoanalysis focusing explicitly on whether psychoanalysis is part of the sciences, and if not, where it belongs. Many psychoanalysts, beginning with Freud, have considered their discipline a science. In this book, Caper examines this claim and investigates the relationship of theory to observation in both philosophy and the experimental sciences and explores how these observations differ from those made in psychoanalytic interpretation. _Building Out into the Dark_ also (...) explores topics including: the origins of psychoanalysis in the art of medicine the therapeutic effect of psychoanalysis the archaic superego psychoanalysis with the individual and groups what makes psychoanalytic work unique. _Building Out into the Dark_ offers a thoughtful consideration of the nature of psychoanalytic knowledge and how it is gained. The book's accessible and concise style makes it a useful introductory resource for students studying psychoanalysis, for psychotherapists who are curious about the distinction between psychoanalysis and other forms of therapy as well as those interested in placing psychoanalysis in the context of current cultural and intellectual developments. (shrink)

Current cosmological observations place little constraints on the nature of dark matter, allowing the development of a large number of models and various methods for probing their properties, which seem to provide ideal grounds for the employment of robustness arguments. In this article, the extent to which such arguments can be used to overcome various methodological and theoretical challenges is examined. The conclusion is that while robustness arguments have a limited scope in the context of dark matter research, they can (...) still be used for increasing the scientists’ confidence about the properties of specific models. (shrink)

Many studies in big data focus on the uses of data available to researchers, leaving without treatment data that is on the servers but of which researchers are unaware. We call this dark data, and in this article, we present and discuss it in the context of high-performance computing facilities. To this end, we provide statistics of a major HPC facility in Europe, the High-Performance Computing Center Stuttgart. We also propose a new position tailor-made for coping with dark data and (...) general data management. We call it the scientific data officer and we distinguish it from other standard positions in HPC facilities such as chief data officers, system administrators, and security officers. In order to understand the role of the SDO in HPC facilities, we discuss two kinds of responsibilities, namely, technical responsibilities and ethical responsibilities. While the former are intended to characterize the position, the latter raise concerns—and proposes solutions—to the control and authority that the SDO would acquire. (shrink)

Many studies in big data focus on the uses of data available to researchers, leaving without treatment data that is on the servers but of which researchers are unaware. We call this dark data, and in this article, we present and discuss it in the context of high-performance computing facilities. To this end, we provide statistics of a major HPC facility in Europe, the High-Performance Computing Center Stuttgart. We also propose a new position tailor-made for coping with dark data and (...) general data management. We call it the scientific data officer and we distinguish it from other standard positions in HPC facilities such as chief data officers, system administrators, and security officers. In order to understand the role of the SDO in HPC facilities, we discuss two kinds of responsibilities, namely, technical responsibilities and ethical responsibilities. While the former are intended to characterize the position, the latter raise concerns—and proposes solutions—to the control and authority that the SDO would acquire. (shrink)

Studies have shown that performance‐dependent monetary rewards facilitate visual perception. However, no study has examined whether such a positive effect is limited to the rewarded task or may be generalized to other tasks. In the current study, two groups of people were asked to perform two visual perception tasks, one being a reward‐relevant task and the other being a reward‐irrelevant task. For the reward‐relevant task, the experimental group received performance‐dependent monetary rewards, whereas the control group did not. For the reward‐irrelevant (...) task, both groups were not rewarded. The two tasks were randomly intermixed trial by trial (Experiment 1) or presented block by block (Experiment 2) or session by session (Experiments 3a, 3b, and 3c). Results showed that performance‐dependent monetary rewards improved participants' performance on the relevant task in all experiments and impaired their performance on the irrelevant task in Experiments 2, 3a, 3b, and 3c. These results suggested that monetary rewards might incur a cost on reward‐irrelevant tasks. Finally, the benefit of monetary rewards disappeared when they were no longer provided during the final session. This is the first study that reveals both the bright and dark sides of the performance‐dependent monetary rewards in visual perception. (shrink)

Democracy has been a flawed hegemony since the fall of communism. Its flexibility, its commitment to equality of representation, and its recognition of the legitimacy of opposition politics are all positive features for political institutions. But democracy has many deficiencies: it is all too easily held hostage by powerful interests; it often fails to advance social justice; and it does not cope well with a number of features of the political landscape, such as political identities, boundary disputes, and environmental crises. (...) Although democracy is valuable it fits uneasily with other political values and is in many respects less than equal to the demands it confronts. In this volume prominent political theorists and social scientists present original discussions of such central issues. Democracy's Values deals with the nature and value of democracy, particularly the tensions between it and such goods as justice, equality, efficiency, and freedom. (shrink)

Baker argues that quantitative parsimony—the principle that hypotheses requiring fewer entities are to be preferred over their empirically equivalent rivals—is a rational methodological criterion because it maximizes explanatory power. Baker lends plausibility to his account by confronting it with the example of postulating of the neutrino in order to resolve a discrepancy in Beta decay experiments. Baker’s account is initially attractive, but I argue that its details are problematic and that it yields undesirable consequences when applied to the case of (...) astrophysical dark matter. Baker has not succeeded in showing why quantitative parsimony is a theoretical virtue. (shrink)

No final statement can be made regarding the relations between science and policy-making. Knowledge, values, and techniques are interrelated, cumulative, and constantly changing. They are derived from man's responses to the complicated interactions between physical, biological, and cultural phenomena. Final answers are impossible because the answers themselves are part of the world and therefore are factors in changing it. We see through a glass darkly, whether it be the giant glass of Palomar or the eye-piece of the electron microscope.

To a packed audience in Clark Hall, Sheila Jasanoff, a distinguished scholar and former president of the Society for Social Studies of Science, gave the plenary address for “Where has STS Traveled,” a commemorative gathering of the fortieth anniversary of the inaugural meeting of the 4S. Not only was this meeting located in the very same room as the first gathering, but also many of the original members had traveled from far and wide to Cornell University to reminisce and (...) reflect on the academic field they had established, as well as imagine the possibilities of the next forty years. In response to a question about the direction of STS, Professor Jasanoff suggested that the 4S had not turned its reflective gaze inward to examine the politics of its own society, nor had it spent much effort interrogating the society’s contribution to social policy or enduring social problems. As I heard Jasanoff speak about our collective need for reflection and reflexivity, I had to wonder whether, and to what extent, we were ready to reflect on the subject matter of race and racism in this mostly color-blind field of inquiry. (shrink)

Newtonian physics is based on Newtonian calculus applied to Newtonian dynamics. New paradigms such as ‘modified Newtonian dynamics’ change the dynamics, but do not alter the calculus. However, calculus is dependent on arithmetic, that is the ways we add and multiply numbers. For example, in special relativity we add and subtract velocities by means of addition β1⊕β2=tanh+tanh-1)\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\beta _1\oplus \beta _2=\tanh \big +\tanh ^{-1}\big )$$\end{document}, although multiplication β1⊙β2=tanh·tanh-1)\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} (...) \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\beta _1\odot \beta _2=\tanh \big \cdot \tanh ^{-1}\big )$$\end{document}, and division β1⊘β2=tanh/tanh-1)\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\beta _1\oslash \beta _2=\tanh \big /\tanh ^{-1}\big )$$\end{document} do not seem to appear in the literature. The map fX=tanh-1\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$f_{\mathbb{X}}=\tanh ^{-1}$$\end{document} defines an isomorphism of the arithmetic in X=\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\mathbb{X}}=$$\end{document} with the standard one in R\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\mathbb{R}}$$\end{document}. The new arithmetic is projective and non-Diophantine in the sense of Burgin, 1977), while ultrarelativistic velocities are super-large in the sense of Kolmogorov, 1961). Velocity of light plays a role of non-Diophantine infinity. The new arithmetic allows us to define the corresponding derivative and integral, and thus a new calculus which is non-Newtonian in the sense of Grossman and Katz. Treating the above example as a paradigm, we ask what can be said about the set X\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\mathbb{X}}$$\end{document} of ‘real numbers’, and the isomorphism fX:X→R\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$f_{{\mathbb{X}}}:{\mathbb{X}}\rightarrow {\mathbb{R}}$$\end{document}, if we assume the standard form of Newtonian mechanics and general relativity but demand agreement with astrophysical observations. It turns out that the observable accelerated expansion of the Universe can be reconstructed with zero cosmological constant if fX≈0.8sinh/\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$f_{\mathbb{X}}\approx 0.8\sinh /$$\end{document}. The resulting non-Newtonian model is exactly equivalent to the standard Newtonian one with ΩΛ=0.7\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\Omega _\Lambda =0.7$$\end{document}, ΩM=0.3\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\Omega _M=0.3$$\end{document}. Asymptotically flat rotation curves are obtained if ‘zero’, the neutral element 0X\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$0_{{\mathbb{X}}}$$\end{document} of addition, is nonzero from the point of view of the standard arithmetic of R\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\mathbb{R}}$$\end{document}. This implies fX-1=0X>0\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$f^{-1}_{{\mathbb{X}}}=0_{{\mathbb{X}}}>0$$\end{document}. The opposition Diophantine versus non-Diophantine, or Newtonian versus non-Newtonian, is an arithmetic analogue of Euclidean versus non-Euclidean in geometry. We do not yet know if the proposed generalization ultimately removes any need of dark matter, but it will certainly change estimates of its parameters. Physics of the dark universe seems to be both geometry and arithmetic. (shrink)

Rarely does research in the history and philosophy of science lead to new empirical results, but that is exactly what has happened in one of the essays of this special issue: Rang and Grebe-Ellis have developed new experimental techniques to perform measurements Goethe proposed 217 years ago. These measurements fit neatly with Goethe’s idea of polarity—his complementary spectrum is not only an optical, but also a thermodynamical counterpart of Newton’s spectrum. I use the new measurements, firstly, to argue against (...) the asymmetries between light and darkness posited by Lyre and Schreiber; and, secondly, to explicate the alternative theory that Goethe had introduced to urge scientific pluralism. In my replies to exegetical criticism by Böhler, Hampe and Zemplén, I show that the main goal of Goethe’s Farbenlehre was indeed to expose symmetries between light and darkness. Furthermore, I argue that it is worthwhile to focus on the experiments, arguments and hypotheses of the Farbenlehre, and not merely on rhetorical, narrative or stylistical aspects, as Böhler and Hampe would have it. Goethe’s criticism of Newton is often dismissed, but it is in fact surprisingly relevant today. (shrink)

This two-volume collection of cutting edge thinking about science and religion shows how scientific and religious practices of inquiry can be viewed as logically compatible, complementary, and mutually supportive. Features submissions by world-leading scientists and philosophers Discusses a wide range of hotly debated issues, including Big Bang cosmology, evolution, intelligent design, dinosaurs and creation, general and special theories of relativity, dark energy, the Multiverse Hypothesis, and Super String Theory Includes articles on stem cell research and Bioethics by William Hurlbut, (...) who served on President Bush's Bioethics Committee. (shrink)

This two-volume collection of cutting edge thinking about science and religion shows how scientific and religious practices of inquiry can be viewed as logically compatible, complementary, and mutually supportive. Features submissions by world-leading scientists and philosophers Discusses a wide range of hotly debated issues, including Big Bang cosmology, evolution, intelligent design, dinosaurs and creation, general and special theories of relativity, dark energy, the Multiverse Hypothesis, and Super String Theory Includes articles on stem cell research and Bioethics by William Hurlbut, (...) who served on President Bush's Bioethics Committee. (shrink)

This paper challenges the first Gettier counterexample to the tripartite account of knowledge. Noting that 'the man who will get the job' is a description and invoking Donnellan's distinction between their 'referential' and 'attributive' uses, I argue that Smith does not actually believe that the man who will get the job has ten coins in his pocket. Smith's ignorance about who will get the job shows that the belief cannot be understood referentially, his ignorance of the coins in his pocket (...) shows that it cannot be understood attributively. An explanation for why Smith appeared to have justified true belief is given by distinguishing between 'belief' and 'belief in truth'. Smith believes the sentence 'the man who will get the job has ten coins in his pocket' to be true (he mistakenly believes that Jones will get the job, of whom he knows that he has ten coins in his pocket) (hence his 'belief'), the sentence is true (hence 'truth'), and he has sufficient reason to assent to it (hence his 'justification'). But he does not believe the proposition expressed. Hence he does not know it either. (shrink)

Explores some steps toward non-assimilative encounters in the "global village.".

Religion happens -- Crackers and grape juice -- Attention collection -- Choose your ancestors carefully -- I learned it by watching you -- Hurry up and matter! -- The web, the net, and the verse -- The chother -- Policy is liturgy writ large -- Strange negotiations.

Comparative political theory is at best an embryonic and marginalized endeavor. As practiced in most Western universities, the study of political theory generally involves a rehearsal of the canon of Western political thought from Plato to Marx. Only rarely are practitioners of political thought willing (and professionally encouraged) to transgress the canon and thereby the cultural boundaries of North America and Europe in the direction of genuine comparative investigation. Border Crossings presents an effort to remedy this situation, fully launching a (...) new era in political theory. Thirteen scholars from around the world examine the various political traditions of West, South, and East Asia and engage in a reflective cross-cultural discussion that belies the assumptions of an Asian "essence" and of an unbridgeable gulf between West and non-West. The denial of essential differences does not, however, amount to an endorsement of essential sameness. As viewed and as practiced by contributors to this ground-breaking volume, comparative political theorizing must steer a course between uniformity and radical separation--this is the path of "border crossings.". (shrink)

The unreduced many-body interaction problem solution, absent in usual science framework, reveals a new quality of emerging multiple, equally real but mutually incompatible system configurations, or “realisations”, giving rise to the universal concept of dynamic complexity and chaoticity. Their imitation by a single, “average” realisation or trajectory in usual theory (corresponding to postulated “exact” or perturbative problem solutions) is a rough simplification of reality underlying all stagnating and emerging problems of conventional (unitary) science, often in the form of (...) missing, or “dark”, entities and “hidden variables”. We show how the application of unreduced interaction problem solution and the ensuing concept of dynamic complexity provides the desired causally complete and intrinsically unified solutions to respective unitary science problems in the entire range of complexity levels, from elementary particles and cosmology to emergent consciousness and modern development crisis, implying real, essential and urgently needed progress. (shrink)

There is an ongoing concern about workplace ethics. Many voices say that our educational system ought to do something about it, but they do not agree about how to do this. By the time students reach post‐secondary education, they will have already developed a general moral sense. The concern is whether their moral sense is sufficient for ethical situations in the workplace. If not, post‐secondary education is expected to close the gap. In order to do this, educators need information about (...) what is missing. Educators can set clear, work‐related objectives and use classroom activities to reach those objectives based on an identification of these gaps. (shrink)

What darkness was the ‘Enlightenment’ supposed to have removed? The answer is irrational forms of religion. Most of the ‘enlightened’ took the view that revealed religion was irrational and that natural religion could be rational; but some were sceptical about natural religion too. Hume was the most honest and the most penetrating thinker of the latter group. His biographer, Professor E. C. Mossner, is not alone in believing that the Dialogues concerning Natural Religion is ‘his philosophical testament’.

What darkness was the ‘Enlightenment’ supposed to have removed? The answer is irrational forms of religion. Most of the ‘enlightened’ took the view that revealed religion was irrational and that natural religion could be rational; but some were sceptical about natural religion too. Hume was the most honest and the most penetrating thinker of the latter group. His biographer, Professor E. C. Mossner, is not alone in believing that the Dialogues concerning Natural Religion is ‘his philosophical testament’.

This is a short story about vision, thought, and contradiction and the role they play in the first half of Hegel's Science of Logic. The Logic begins with a descent, in this case, the fall from Being into Nothingness. Later, at nearly the exact middle of each text, there is a certain paradox in which everything is at stake, the category of contradiction. At this exact moment, thinking both fails and is birthed anew in a speculative guise. In this (...) section, we engage some of Analytic philosophy's influential interpretations of Hegel's strange use of contradiction. In order to get there, we turn to a curious art work, James Turrell's Pleiades, as an aesthetic example of that first fall. We will then progress through the text, with thought and vision as our dual guide, at quite a quick pace, not slowing down until we enter Hegel's story of contradiction, where I will show the explosive nature of contradiction. This will allow us to see how Hegel harnesses the power of contradiction in order to generate the second half of the story of the Science of Logic. I begin with the descent of being into nothingness, the moment when darkness. (shrink)

From respected thinker and public intellectual David Dark comes We Become What We Normalize, both a cultural critique and a robust summons to resist complicity when it comes to conversations on politics, religion, and media. Dark offers a spirited call to witness to ethics, community, and change for ourselves and the worlds we inhabit.

Proceedings of the First Conference of the International Society for Hermeneutics and Science.