Elucidating distinct morphological atrophy patterns of Alzheimer’s disease and its prodromal stage, namely, mild cognitive impairment helps to improve early diagnosis and medical intervention of AD. On that account, we aimed to obtain distinct patterns of voxel-wise morphological atrophy and its further perturbation on structural covariance network in AD and MCI compared with healthy controls. T1-weighted anatomical images of matched AD, MCI, and HCs were included in this study. Gray matter volume was obtained using voxel-based morphometry and compared among three (...) groups. In addition, structural covariance network of identified brain regions exhibiting morphological difference was constructed and compared between pairs of three groups. Thus, patients with AD have a reduced hippocampal volume and an increased rate of atrophy compared with MCI and HCs. MCI exhibited a decreased trend in bilateral hippocampal volume compared with HCs and the accelerated right hippocampal atrophy rate than HCs. In AD, the hippocampus further exhibited increased structural covariance connected to reward related brain regions, including the anterior cingulate cortex, the putamen, the caudate, and the insula compared with HCs. In addition, the patients with AD exhibited increased structural covariance of left hippocampus with the bilateral insula, the inferior frontal gyrus, the superior temporal gyrus, and the cerebellum than MCI. These results reveal distinct patterns of morphological atrophy in AD and MCI, providing new insights into pathology of AD. (shrink)

Perceptual attention is essential to both thought and agency, for there is arguably no demonstrative thought or bodily action without it. Psychologists and philosophers since William James have taken attention to be a ubiquitous and distinctive form of consciousness, one that leaves a characteristic mark on perceptual experience. As a process of selecting specific perceptual inputs, attention influences the way things perceptually appear. It may then seem that it is a specific feature of perceptual representation that constitutes what it is (...) like to consciously attend to an object. In fact conscious attention is more complicated. In what follows, I argue that the phenomenology of conscious attention to what is perceived involves not just a way of perceptually locking on to a specific object. It necessarily involves a way of cognitively locking on to it as well. (shrink)

This article provides a detailed overview of the neuroscience of consciousness.

本书包括:进化论革命者颉德之学说、尼采氏之教育观、德国文化大改革家尼采传、叔本华与尼采、德国大哲学者尼采之略专及学说等内容。.

To study whether Tai Chi practice can improve the brain connectivity of the prefrontal lobe of college students, the positive psychological capital questionnaires and resting EEG signals were acquired from 50 college students including 25 TC practitioners and 25 demographically matched TC healthy controls. The results showed that the score of the positive psychological capital questionnaire of the TC group was significantly higher than that of the control group, and the node degree of the frontal lobe and temporal lobe of (...) both groups was positively correlated with the score of the positive psychological capital questionnaire. In addition, the response time of the TC group under auditory stimulation was significantly shorter than that of the control group, and there was a significant positive correlation between response time and its characteristic path length, and a significant negative correlation with global efficiency. Meanwhile, during the selected range of sparsity, the difference in global network parameters between two groups is significant in the alpha band. Under all single sparsity, the clustering coefficient, global efficiency, and local efficiency of the TC group have a higher trend, while the characteristic path length tended to be shorter. In the analysis of the local characteristics of the resting brain functional network, it was found that the node degree of the frontal lobe and temporal lobe of the TC group was higher, and the difference was significant in some nodes. These results all point to the fact that TC practice has a certain impact on specific brain areas of the brain. (shrink)

Why Lazarus Laughed explicates the essential doctrine shared by the traditions of Zen Buddhism, Advaita, and Tantra. Wei Wu Wei has become an underground spiritual favorite whose fans anxiously await each reissued book.

The effect of environmental, social, and governance (ESG) activities on corporate financial performance (CFP) could be linear or nonlinear. However, inconsistent results remain a research gap and thus need to be re-examined. By drawing on stakeholder theory and the neoclassical economics perspective while using the panel data of 155 Chinese listed firms from 2010 to 2020, system generalized method of moments (GMM) estimation results revealed an inverted U-shaped relationship between ESG and CFP. Moreover, by drawing on the institutional-based view, it (...) was determined that government subsidies moderate the inverted U-shaped relationship between ESG and CFP. Specifically, we found that the inverted U-shaped effect of ESG on CFP is weakened when government subsidies are high. This study contributes to the literature by confirming the presence of a curvilinear relationship between ESG and CFP. This study also generates meaningful implications suggesting that the governmental role in ESG is salient in mitigating associated financial costs for firms, thereby ultimately affecting CFP. (shrink)

本书介绍的内容包括:全球化与后现代性、后现代思潮与全球化生态、后现代性与全球文化、全球化时代的后现代主义。.

本书分为7篇共18章,大致分三部分,包括论人性的属性、特征,以及欲求自我实现的机制和形态;论欲求的各种法则以及欲望变化的无穷趋势;论恶欲的产生和对立给个人及国家带来的灾难等内容。.

abstract Mou Zongsan used to say that in Western philosophy there exist three different traditions. The first is the tradition of Plato and Aristoteles, the second is the tradition of Kant and Hegel, and the last is the tradition of Leibniz and Russell. I am afraid, however, that this kind of interpretation is already outdated and incapable of encompassing the rich variegations of Western philosophy as a whole. In my view, the various options would have been exhausted by supplementing the (...) preceding list with the tradition founded by Husserl and Heidegger and the one set up by Whitehead. All of these traditions together encapsulate the most important domains of philosophy, such as ontology, epistemology, and axiology. In this article I closely investigate the epistemological thought of Bertrand Russell in order to find out whether it contains any aspects from which we can borrow and learn. (shrink)

本书庋集吴氏法学著述二十五篇,概分为三大部分。吴氏与霍姆斯大法官的部分通信和著名的《吴氏宪草》,作为附录,一并收刊。.

本文集收入“传统道德文化的继承与批判”、“中国传统文化的现代化意义”、“关于中国传统道德和文化的几个问题”等文章61篇。.

Ever since Charles Goodwin’s seminal works on gaze, there has been a long-standing interest in Conversation Analysis in the interrelationship between talk and bodily conduct in the accomplishment of social action. Recently, a small but emerging body of research has explored the ways in which embodied conduct figures in the organization and operations of repair. In this article, I take up a similar theme and investigate the interaction between talk and iconic gestures in same-turn self-initiated repair in Mandarin conversation. The (...) phenomenon I examine concerns the use of what I call “gestural repair.” The analysis focuses on how such repair can intertwine with talk in multi-stage operations in the progressivity and resolution of repair. The data are drawn from 50 hours of naturally-occurring conversations collected in China. Some unique features of such gestural repair observed in the Mandarin data are also discussed. (shrink)

Does context influence our appreciation of beauty? To answer this question, two experiments were conducted to determine the effect of contextual aesthetics on the recognition of moral behavior. Experiment 1 demonstrated that individuals in a high-aesthetic context had a quicker recognition time for moral behavior than those in a low-aesthetic context. In a low-aesthetic context, individuals recognize immoral behavior more quickly than in a high aesthetic context. Individuals showed greater recognition rates for moral behavior in a high aesthetic context and (...) higher recognition for immoral behaviors in a low aesthetic context for behavior with unclear information. Experiment 2 revealed that individual fixation counts were smaller under the conditions of high aesthetic context and moral behavior than under the conditions of low aesthetic context and moral behavior, indicating a correlation between low aesthetic context and immoral behavior. This study shows that high aesthetic context facilitates the recognition of moral behavior, which has implications for moral education. (shrink)

EDITOR’S ABSTRACTThis article argues that Shang Yang’s philosophy of law was not only a means to enrich the state and strengthen its army, but also envisioned the orderly rule of all All-under-Heaven. Through a fair, universal, and reliable use of rewards, punishments, and also teaching, this vision of laws could ultimately lead to the promotion of moral values, popular consensus, and people’s self-governance. While the authors admit that in Shang Yang’s own historical context, law was no more than a tool (...) used by the ruler to suppress his people, potentially his ideas could contribute to a future Chinese society fully ruled by law and morality, and inspired by the rule of law. (shrink)

In The Pragmatics of Text Messaging: Making Meaning in Messages Michelle A. McSweeney seeks to explore the meaning to be found in the labyrinth of text messaging language, and offers explanations b...

Both the doctor and the patient have rights to terminate an implantable cardioverter-defibrillator device for reasons of futility or autonomyImplantable devices have a long history in medicine with artificial hips being implanted since 1925, pacemakers since 1957, Starr-Edwards heart valve since 1961, artificial hearts since 1982 and ventricular assist devices since 1991. The ethics of deactivation or removal of these devices were not an issue until the use of implantable cardioverter defibrillator device, as the ICD can produce considerable distress from (...) defibrillation shocks in end-of-life patients. However, development of a clear ethics for ICD is critical as the massive technological advances in implantable heart failure devices will soon produce an epidemic of patients with implanted devices and end-of-life diseases. Should one turn off a biventricular pacer at the request of a patient who is having recurrent disabling heart failure? Should one turn off an AbioCor artificial heart in a patient who developed a severe disabling stroke from the device? Who has the right to turn off the device? Does the doctor have the right to turn it off, against the patient’s wishes, for reasons of futility? Does the patient have the right to turn it off, against the doctor’s wishes, and if so, for what reasons?In this issue of the Journal of Medical Ethics, England et al1 argue that the classification of an implantable device determines the rights of device deactivation. At the one end of the spectrum, there are semi-implanted devices like an intra-aortic balloon pump or a ventilator, where the doctor has the right to turn off the supportive therapy by commission on grounds …. (shrink)

Attention has been studied in cognitive psychology for more than half a century, but until recently it was largely neglected in philosophy. Now, however, attention has been recognized by philosophers of mind as having an important role to play in our theories of consciousness and of cognition. At the same time, several recent developments in psychology have led psychologists to foundational questions about the nature of attention and its implementation in the brain. As a result there has been a convergence (...) of interest in fundamental questions about attention. This volume presents the latest thinking from the philosophers and psychologists who are working at the interface between these two disciplines. Its fourteen chapters contain detailed philosophical and scientific arguments about the nature and mechanisms of attention; the relationship between attention and consciousness; the role of attention in explaining reference, rational thought, and the control of action; the fundamental metaphysical status of attention, and the details of its implementation in the brain. These contributions combine ideas from phenomenology, neuroscience, cognitive psychology, and philosophy of mind to further our understanding of this centrally important mental phenomenon, and to bring to light the foundational questions that any satisfactory theory of attention will need to address. (from OUP website). (shrink)

The present study examined gender differences in the distribution of creative abilities through the lens of the greater male variability hypothesis, which postulated that men showed greater interindividual variability than women in both physical and psychological attributes. Two hundred and six undergraduate students in Hong Kong completed two creativity measures that evaluated different aspects of creativity, including: a divergent thinking test that aimed to assess idea generation and a creative problem-solving test that aimed to assess restructuring ability. The present findings (...) extended the research of greater male variability in creativity by showing that men generally exhibited greater variance than women in the overall distribution of the creativity scores in both divergent thinking and creative problem solving, despite trivial gender differences in mean scores. The findings further enriched the discourse of the greater male variability hypothesis by showing interesting domain-specific gendered patterns: greater male variability was more likely to occur in figural forms of creativity, with larger effect sizes, when compared to the variability in verbal forms of creativity; and mixed gendered patterns were found in the upper tails of the creativity score distribution with respect to the verbal domain but not the figural one, despite greater male representation being consistently observed in the lower tail of the distribution. Possible underlying mechanisms and implications were discussed. (shrink)

Ample manpower and material were mobilized for research on Liuhsia Chih in 1974. A thorough investigation of the life of a very famous leader of the working people's uprising and a clarification of erroneous historical legends about him are important for studies of history. Undoubtedly, a correct understanding of this historical character's features and propaganda about his revolutionary deeds will be conducive to the cause of socialism in our country. It is regrettable that some widely publicized works in 1974 were (...) rather inferior in quality and had unfavorable effects because their authors accepted the guidance of erroneous political thought and because the academic atmosphere was somewhat foul. As a result, people became confused. All this was caused by the control, interference and destruction of the "gang of four.". (shrink)

本书主要论述了如何看待当代西方社会的文化批判理论、与西方现代化理论研究的意义、社会经济学的基本内涵、生态经济学理论及方法论的近期发展、如何看待颇有争议的“文明冲突论”等问题。.

本书论及的是当代西方社会科学和人文科学的现状及发展趋势。作者为国内众多著名学者,如刘放桐、黄长著等,他们从当代社会科学和人文科学发展的各个角度全面论述了这个问题。.

The author proposes to add another dichotomy to the list of essential tensions proposed by Professor Duda, namely beauty and ugliness. Physicists believe that only beautiful theories describe the world correctly, and that General Relativity is one of the most beautiful physical theories. The author explains why physicists regard this theory as beautiful.

With the recent rise of the philosophy of scientific practices, SSK (Sociology of Scientific Knowledge), and feminist approaches to the philosophy of science, a new perspective is gradually coming into being, holding that the starting point for scientific research is opportunity. Opportunistic features in solar neutrino experiments, Opportunistic features of complexity studies emerging from economics, and the measurement of insects' flight can prove the above perspective from different angels. It is important and significant to determine whether the starting point for (...) scientific research is opportunity, a problem, or an observation. /// 近年来由于科学实践哲学的兴起，以及 SSK 和女性主义科学哲学研究的兴起， 科学研究始于机会的观点正在悄然形成之中。太阳中微子实验、复杂性研究和昆虫 飞行测量等案例都从不同角度证明了 "科学研究始于机会" 的观点。区别科学研究 "始于机会"、"始于问题" 和 "始于观察" 这三种观点，是重要而且有意义的。. (shrink)