Modern insan eleştiriyi, neredeyse hava kadar, su kadar yaşamsal saymaktadır. Daha iyi bir dünyada yaşama isteği, verili olanlarla yetinmemeyi, gelenekleri, yerleşik değerleri sorgulamayı beraberinde getirmektedir. Felsefi eleştiri, sadece belli bir görüşe itiraz etmekle sınırlı bir tutum değildir; o aynı zamanda kendi dayanaklarının sağlamlığı ile de ilgilidir. Bilimlerde sıklıkla karşılaşılan yapıcı ya da olumlu eleştiri, başta felsefe olmak üzere sosyal bilimlerde yıkıcı bir niteliğe bürünmektedir. Felsefi eleştirinin yıkıcılığının nihilizmle sonuçlanmaması için bu eleştiri türünün de yapıcı bir nitelikle donatılması gerekir. Bu çalışmada (...) felsefi eleştirinin normları olabileceği öne sürülmektedir. Bu normlardan en bilinen ve kabul gören üç ilke tespit edilerek bu ilkelerin felsefi eleştirinin temellendirilmesinde oynadıkları rolün gösterilmesi amaçlanmaktadır. Böylelikle felsefenin de tıpkı bilimler gibi siyasal iktidarların hizmetinde olmak yerine, gerçeğin peşinden gidebileceğinin olası olduğu gösterilecektir. (shrink)

One of the most dynamic areas of plant molecular biology is the investigation of the actions of three classes of herbicides: s‐triazines (atrazine, simazine), glyphosate, and sulfonylureas (chlorsulfuron, sulfometuron methyl) (Figure 1). The results of this work are expected to provide the first significant applications of plant biotechnology: directly, in the genetic engineering of crop plants resistant to specific herbicides and, indirectly, in providing a molecular basis for the rational design of new herbicides for specific biological targets.s‐Triazines affect photosynthesis by (...) inhibiting the binding of quinones to the chloroplast membrane QB protein. An s‐triazine resistant QB protein isolated from weeds in fields consistently treated with the herbicide has a serine in place of a glycine in this highly conserved protein. Glyphosate inhibits 5‐enolpyruvyl‐shikimate‐3‐phosphate synthase (EPSP synthase), an enzyme in the aromatic amino acid biosynthetic pathway. Mutagenized bacteria produce a resistant EPSP synthase with a substitution of serine for proline. Sulfonylureas inhibit the acetolactate synthase (ALS) of bacteria, yeast, and higher plants; this enzyme catalyzes the first step in the synthesis of branched chain amino acids. Resistant ALS has been found in bacteria, yeast and tobacco with a proline substituted by serine in yeast ALS. These findings provide a strong basis for developing projected plant biotechnology applications. (shrink)

This article describes the development of a computerized version of a measure of ethical sensitivity to racial and gender intolerance, the Racial Ethical Sensitivity Test. The REST was based on James Rest's 4-component model of moral development and the professional codes of ethics from school-based professions. The new version, Racial and Ethical Sensitivity Test-Compact Disk, consists of 5 videotaped scenarios followed by an interactive "interview" presented on compact discs. Data from a study with 58 students provides initial validation of the (...) REST-CD. Ethical sensitivity to racial and gender intolerance in schools, as measured by the REST-CD, was moderately related to attitudes toward racial and gender equity issues in society as measured by the Quick Discrimination Index. The results provide evidence for both interrater and internal reliability of the REST-CD scores. This study also tests the hypothesized relationship between REST-CD scores and previous multicultural and ethics course work. Students with multicultural and ethics course experience have scored significantly higher on the REST-CD than students without course work. The paper-and-pencil tests are not significantly related to previous ethics/multicultural course work. In this article, we discuss the implications of the results and directions for future research. (shrink)

On considère souvent, non sans raison d’ailleurs, que la tolérance est un des paradigmes de la modernité occidentale. En effet, il y a un « concept spécifiquement moderne » de tolérance qui s’élabore progressivement dans le contexte particulier de la Réforme et de l’éclatement confessionnel du xvie siècle : la « coexistence civile » est le modus vivendi qui a été trouvé après moults débats pour mettre fin aux terribles guerres de religion entre catholiques et protestants. Tolerantia subit un...

We present computational modeling results based on a self‐paced reading study investigating number attraction effects in Eastern Armenian. We implement three novel computational models of agreement attraction in a Bayesian framework and compare their predictive fit to the data using k‐fold cross‐validation. We find that our data are better accounted for by an encoding‐based model of agreement attraction, compared to a retrieval‐based model. A novel methodological contribution of our study is the use of comprehension questions with open‐ended responses, so that (...) both misinterpretation of the number feature of the subject phrase and misassignment of the thematic subject role of the verb can be investigated at the same time. We find evidence for both types of misinterpretation in our study, sometimes in the same trial. However, the specific error patterns in our data are not fully consistent with any previously proposed model. (shrink)

Bu çalışmada, bir yandan bilgiye yol açması bağlamında deneyimin inanca kaynak oluşturması, öte yandan insan edimlerine yol açması bağlamında inancın deneyimlenmesine olanak oluşturması nedeniyle inanç-deneyim ilişkisi irdelenecektir. İnanç-deneyim ilişkisinin olanaklılığı ve bu ilişkinin kuşkulu doğası, Davidson ve Wittgenstein gibi iki önde gelen çözümleyici filozofun konuyla ilgili açıklamaları dikkate alınarak araştırılmaktadır.Yazının ana savını şu temel fikir oluşturmaktadır: Sanılanın aksine, ne deneyimler inanç için sağlam ve kesin bir temel oluştururlar ne de deneyimler bilinmek için inançlara gereksinim duyarlar. In this paper, the relationship (...) between belief and experience will be investigated because on the one hand, experience creates a source for beliefs which leads knowledge and on the other hand it makes the experience possible, which leads human actions. Considering the analysis of two prominent analytic philosophers Davidson and Wittgenstein, the relationship of belief and experience, and the questionable nature of this relationship will be studied. The basic claim of this paper consists of the following primary idea: Contrary to what is believed, neither experiences form a firm and certain basis for beliefs, nor experiences are in need of beliefs to be known. (shrink)

At first glance, what scientific progress means seems to be a quickly answered question. It is not easy to think of the sciences without progress; sciences and the notion of progress seem identical in general. Describing the nature of scientific progress is an important task that will have practical and theoretical consequences. The approach, which argues that the background on which sciences are based does not have a historical or cultural character following the positivist interpretation, accepts sciences as testing the (...) validity of observation and experiment data to a large extent. On the other hand, the tendency that emphasizes that the complex functioning of the history of science has an indelible mark on scientific theories prefers to build sciences on a historical and social basis. How both major approaches ground the idea of scientific progress profoundly affects both our understanding of the nature of scientific knowledge and the way we do science. This paper aims to evaluate scientific progress based on the views of prominent philosophers of science in the twentieth century. (shrink)

Various approaches have been made for understanding the nature of science and scientific knowledge. The social factors that played some role during the choice of scientific theories in the nineteenth century popularised the opinion that the scientific knowledge is the subject of a sociological research. During the ongoing discussions, one of the explanation or the justification models that was proposed is known as “the Strong Programme.” The main claim of “the Strong Programme” is that the social factors have a determining (...) role for the choice of scientific theories, rather than the rational and universal criteria one may expect. Hence, those who were behind this view rejected all of the rational analyses made for the sciences and the scientific methods. In this paper, we try to investigate the validity of the claims of “the Strong Programme,” and to clarify whether it is possible to understand the real nature of science without any rational approach. It is argued that it would be insufficient to determine the content of the science merely by the social factors, the natural facts might be meaningful by themselves as well. -/- Bilimin ve bilimsel bilginin doğasını açıklamak için farklı pek çok yaklaşım geliştirilmiştir. Özellikle ondokuzuncu yüzyıldaki bazı bilimsel kuramların tercihinde toplumsal etmenlerin rolünün gözlemlenmesi, bilimsel bilginin toplumbilimsel bir araştırma konusu olduğu kanısını yaygınlaştırmıştır. Bu süreçte ortaya konan açıklama ve gerekçelendirme modellerinden biri de “Strong Programme” olarak anılandır. “Strong Programme” ın temel savı, bilimsel kuramların tercihinde sanıldığı gibi ussal ve evrensel ölçütlerin değil, toplumsal etmenlerin belirleyici olduğu yönündeydi. Dolayısıyla bu görüşü savunanlar, bilim ve bilimsel yöntem için ortaya konan tüm ussalcı çözümlemeleri reddettiler. Bu çalışmada, “Strong Programme”ın ileri sürdüğü savların haklılığı ve sanıldığı gibi usçu bir yaklaşım olmaksızın bilimin gerçek doğasını anlamanın olanaklı olup olmadığı soruşturulmaktadır. Bilimin içeriğinin bütünüyle ve sadece toplumsal etmenlerce belirlenemeyeceği, doğa olaylarının da kendi başlarına anlamlı olabileceği ileri sürülmektedir. (shrink)

This study examined possible ways to ensure that participants provide fully informed consent for online surveys. Participants were randomly assigned to read either a traditional informed consent or one of three modified versions: enhanced, consent for each key element, or a combination of these two. Those who read the combination version scored higher on a comprehension quiz, guessed at fewer questions, and were more likely to read all of the informed consent than those who received the traditional version. These findings (...) suggest that comprehension can be improved by adopting alternatives to the traditional informed consent. (shrink)

This qualitative study analysed the agency of eight non-abusing mothers in the Turkish Cypriot Community after disclosure that their child had been sexually abused by someone outside the family. The aim was to discover how, after disclosure, such mothers act to protect their children in the contexts of their family and community. The data were gathered via semi-structured in-depth interviews and analysed using Interpretative Phenomenological Analysis. In the nuclear family context, maternal agency emerged in the form of motherhood skills, including (...) emotionally supporting the abused child, double-checking the child’s safety or limiting the child’s mobility, and controlling the actions of adult sons. In the community context, maternal agency was manifested in efforts to prevent men in the extended family or the abuser’s family from concealing the abuse and to obtain informal support from others such as birth or extended family members. The women were usually successful in hiding their reactions or making decisions in their children’s best interest despite frequently having to cope with the reality of living in a restrictive and patriarchal culture. The results emphasise the need for working with the general public and professionals to change the culture of silence and to improve the social support network for sexually abused children and non-abusing family members, especially mothers. (shrink)

Crisis management is a complex problem raised by the scientific community currently. Decision support systems are a suitable solution for such issues, they are indeed able to help emergency managers to prevent and to manage crisis in emergency situations. However, they should be enough flexible and adaptive in order to be efficient to solve complex problems that are plunged in dynamic and unpredictable environments. The approach we propose in this paper addresses this challenge. First, we expose a modelling of information (...) for an emergency environment. Then, we describe an architecture of a multiagent DSS that deals with these information in order to prevent and to manage crisis situations. We focus here on the first level of the system mechanism which intends to perceive and to reflect the evolution of the current situation. Finally, we provide an implementation and an experimentation of the approach using the RoboCupRescue Simulation System. (shrink)

Highly committed teachers spend more effort helping their schools achieve the academic goals. The Covid-19 pandemic had a dire effect on education worldwide. However, just after a few semesters, teachers were asked to return back to schools to teach in person. This study aims to analyze the organizational commitment levels of school teachers before and after the implementation of the Covid-19 pandemic measures that resulted in a two semester break in face-to-face teaching. In this study, a quantitative research method was (...) utilized. A total of 300 teachers’ commitment levels were assessed in a longitudinal test by using a popular tool in order to see the relative change as result of Covid-19 pandemic in Cyprus. The study mainly focuses on gender, marital status, education levels, job experience, and duration of work in the organizations in which the information from responses were statistically analyzed. According to the results of the quantitative analysis, the organizational commitment sampling average were determined to be at medium-high levels. The commitment levels of teachers were observed to decrease after the Covid-19 pandemic measures came to be implemented in schools. A detailed investigation of the school teachers’ commitment levels corresponding to the different demographic characteristics before Covid-19 and after the implementation of normalization measures is presented herein. (shrink)

Activation of resting T lymphocytes through the T cell antigen receptor complex is initiated by critical phosphorylation and dephosphorylation events that regulate the function and interaction of a number of signaling molecules. Key elements in these reactions are members of the Src, Syk and Csk families of protein tyrosine kinases (PTKs) and the phosphotyrosine phosphatases (PTPases) that regulate and/or counteract them, such as CD45. The PTKs can autophosphorylate and phosphorylate each other at multiple sites and, as the result of these (...) interactions, they are induced to phosphorylate other cellular proteins. These phosphorylation events lead to modulation of enzymatic activities and/or serve as binding sites for other signaling molecules having phosphotyrosine‐binding Src homology 2 (SH2) domains. As a result, these proteins translocate to the receptor complexes and are juxtaposed to the kinases that phosphorylate them. Some of the SH2‐domain‐containing polypeptides lack enzymatic activities and, instead, serve as adapter molecules that couple the signal to downstream effectors, such as regulators of the Ras proteins, and further into serine/threonine‐specific protein kinase cascades. Through largely unknown steps these reactions lead to the transcription of previously silent genes, activation of lymphocyte effector functions, progression through the cell cycle and cell proliferation. (shrink)

Study of Non-self (Anātman) in Buddhist philosophy.

Can an ugly experiment be a good experiment? Philosophers have identified many beautiful experiments and explored ways in which their beauty might be connected to their epistemic value. In contrast, the present chapter seeks out (and celebrates) ugly experiments. Among the ugliest are those being designed by AI algorithms. Interestingly, in the contexts where such experiments tend to be deployed, low aesthetic value correlates with high epistemic value. In other words, ugly experiments can be good. Given this, we should conclude (...) that beauty is not generally necessary or sufficient for epistemic value, and increasing beauty will not generally tend to increase epistemic value. (shrink)

Logic; Islamic philosophy; Islam--doctrines.

This book includes critical editions, Turkish translations and short studies of two treatises by Taşköprüzade, one of the most important Ottoman philosophers of the sixteenth century.

This book includes a critical edition and a Turkish translation and a study of an Arabic treatise by Taşköprüzade, one of the most important Ottoman philosophers of the sixteenth century.

Modernism; influence; social and economic aspects; Arab countries; 21st century.

Thinking about Animals in the Age of the Anthropocene makes connections between the Anthropocene discourse and human-animal studies, thus facilitating further interdisciplinary work on the topic of animals in the Anthropocene.