Platforms for sharing genomic and phenotype data have been developed to promote genomic research, while maximizing the utility of existing datasets and minimizing the burden on participants. The value of genomic analysis of trios or family members has increased, especially in rare diseases and cancers. This article aims to argue the necessity of protection when sharing data from both patients and family members. Sharing patients’ and family members’ data collectively raises an ethical tension between the value of datasets and the (...) rights of participants, and increases the risk of re-identification. However, current data-sharing policies have no specific safeguards or provisions for familial data sharing. A quantitative survey conducted on 10,881 general adults in Japan indicated that they expected stronger protection mechanisms when their family members’ clinical and/or genomic data were shared together, as compared to when only their data were shared. A framework that respects decision-making and the right of withdrawal of participants, including family members, along with ensuring usefulness and security of data is needed. To enable this, we propose recommendations on ancillary safeguards for familial data sharing according to the stakeholders, namely, initial researchers, genomic researchers, data submitters, database operators, institutional review boards, and the public and participants. Families have played significant roles in genetic research, and its value is re-illuminated in the era of genomic medicine. It is important to make progress in data sharing while simultaneously protecting the privacy and interests of patients and families, and return its benefits to them. (shrink)

This article is the second translation of the preface and first chapter of Hatano Seiichi's Time and Eternity. A full translation of the text, published by Suzuki Ichiro 鈴木一郎 in 1963, is not easily accessible to most readers, while an excellent partial translation by Joseph O'Leary has recently been made accessible to a wider audience through the monumental work, Japanese Philosophy: A Sourcebook. By providing a short historical introduction to both Hatano's life and works as a great thinker and (...) teacher, this article intends to supplement O'Leary's contribution and therefore enable more readers to gain access to the opening sections of Hatano's Time and Eternity. (shrink)

In lowland South America, breath animates human and non-human bodies, pulsating through the materialities of organisms. Humans, however, should manage their bodies to recast and reconfigure breath in its most life-enhancing manifestations: singing and smoking. These are the specialized domains of those able to manage their vitalities in such a way as to produce potent effects in themselves and in the world around them, including influencing atmospheric conditions, the lives of animals and plants and the harming and healing of others. (...) In these relational onto-epistemologies, intersubjectivity, intercorporality and states of non-cognitive interaffection find new depths. Breath, properly managed, can make and unmake worldly forms, including bodies and the societies they come together in. Focusing on two Amerindian communities, the Warekena of northwestern Rio Negro, Brazil and the Shipibo-Konibo of the Ucayali valley in Eastern Peru, this article examines the interface between human and non-human subjectivities, and how resonant interaffective atmospheric conditions are induced to promote health. (shrink)

Martin Heidegger’s understanding of art and Paul Ricoeur’s reading of the poetics of existence, developed through his hermeneutics of symbols, metaphor and narrative, open an immense vista to a theological thinking that desires to place primacy on the hearing of the symbolic language of poetry and literature. Beginning a few decades ago, various theologians have ventured along this trajectory, but theology still remains under the dominion of “theoria” and “praxis” and is not very open to “poiesis”. The study presented here (...) revisits the book of J.-P. Manigne on the Poetics of Faith from the 1970s, and the doctoral thesis of A. Thomasset on the Poetics of Morality, from the 1990s, showing how poetic reason provoked theological discourse in the second half of the 20th century. It is part of a research still in progress, devoted to other contributions of the beginning of the 21st century. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Bayle, Saint-Evremond, and Fideism:A Reply to Thomas M. LennonGianluca MoriIn a recent article published in this journal Thomas M. Lennon returns to the controversial question of Bayle's attitude towards religion. The point he debates is the particular use that, in expounding his conception of the relationship between faith and reason, Bayle makes of a passage from Saint-Evremond. In Lennon's view the correct interpretation of this point would show that (...) Bayle's fideism is to be "taken at face value" without any hint of irony and with no suspicion of dissimulation or insincerity.1 This would cast doubt on and greatly weaken the interpretation I proposed in my Bayle philosophe.2 My aim here is to respond briefly to Lennon's arguments and to clarify even more briefly what in my opinion is the right perspective in which to consider Bayle's position on this topic.The context in which Bayle quotes Saint-Evremond is to be found in the Eclaircissements he added to the second edition of his Dictionnaire historique et critique (1702) to counter the Dutch religious authorities' harsh criticism of the first edition. In particular the Walloon Consistory accused Bayle of taking a skeptical position that undermined the most important dogmas of Christian faith. In response Bayle wrote the Eclaircissement sur les Pyrrhoniens, a clumsy mosaic of quotations from the Scriptures and from patristic and profane texts, with which he sought to show that his skeptical fideism was not in the least heterodox but indeed the position that most closely reflected true Christianity. The quotation from Saint-Evremond, almost at the end of this text, is taken [End Page 323] from the Conversation du Maréchal d'Hocquincourt et du Père Canaye (written in about 1654).3 The final passage gives a clear idea of the general tone: after having disputed with a churchman the need to subject one's intellect to the yoke of faith, the marshal concludes by saying that he is ready to be crucified "without knowing why." Father Canaye replies: "No reason! That is the true religion. No reason! God has granted you a fine grace, mylord." So, and here Lennon obviously agrees (229), Saint-Evremond's is a text with no shadow of mystical inspiration, indeed strongly tending in the libertine direction, as is clear from the blatant way it pours scorn on the fideist approach.In my interpretation Bayle's use of this quotation does not at all demonstrate his atheism or unbelief, for in my view that question is undecidable. However, the quotation from Saint-Evremond is sufficient—and this is the onlyreason I mentioned it4 —to show that Bayle's approach to fideism is in no way innocent and naive as is sometimes claimed. On the contrary, his texts on this subject contain what amounts to provocations aimed at orthodox readers (to which they immediately reacted). This, together with other more important reasons, leads me to believe that Bayle's professions of Christian faith, though frequent, are generally far from being above suspicion: indeed, almost every line of them raises questions about their actual significance.The provocation contained in the quotation from Saint-Evremond appears in all its rhetorical weight if we associate this text with three other passages from Bayle's works. The first is from the Nouvelles de la république des lettres of December 1686, in which Bayle stresses the unedifying nature of the religious maxims contained in Saint-Evremond's Conversation (which, incidentally, he himself had just had printed in the collection Le Retour des pièces choisies).5 The second is taken from a letter by Jean d'Oulès to Bayle, written in 1696, in which the author deals with exactly the same passage from the Conversation that was later to be reproduced in the Eclaircissement. In this letter d'Oulès quotes the full passage which he considers to be a "naughty text" deliberately written to throw ridicule on the fanatical fideism of Pierre Jurieu.6 The third passage is from Bayle's Continuation des pensées diverses of 1704 in which, shortly after the death of Saint-Evremond, he publicly reveals the poet... (shrink)

Les stratégies de Bayle et de Hume devant la question de l’athéisme sont bien plus proches qu'on ne le croit généralement. Cet accord découle de l’influence constante que Bayle exerça sur Hume. Pour Bayle et pour Hume, l’athéisme et le scepticisme sont très étroitement liés – celui-là n’est qu’une forme du celui-ci. La force des Dialogues sur la religion naturelle de Hume ressort précisément de cette alliance entre athéisme et scepticisme qui, puisant la plupart de ses arguments chez Bayle, aboutit (...) à une critique de la théologie fondée sur une analyse sans concession des fondements épistémologiques de la croyance, tout en se gardant, comme le Straton de Bayle, de réduire l’athéisme à un dogmatisme métaphysique abstrait. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Buddhist-Christian Studies 21.1 (2001) 95-99 [Access article in PDF] The Distinction between ego (e) and ego-Self (e/S): Notes on Religious Practice Based upon Buddhist-Christian Dialogue Yagi Seiichi Toin University The Goal of Religious Practice We cannot see the transcendent as an object. Nor is it the case that the transcendent and the human are two separated realities that are united afterwards. When the Self (Christ in me--Gal. 2:19-20) (...) reveals itself to and in the ego (Gal. 1:16), the ego becomes aware of the Self, which is divine--human or transcendent--immanent. This is called enlightenment.In enlightenment, the ego (hereafter: e) does not vanish.When the Self (hereafter: S) appears to and in the ego, the ego (now a relatively independent part of S) becomes the function of S. The ego, understanding itself as the knot of inner and outer reality, plays the role of the reason of the whole body, the center of which is S. In this case we represent such a person as e/S. e/S is the subjectivity of the religious life. D.T.Suzuki and one of his disciples, Ryomin Akizuki called e/S the "individual qua trans-individual." 1 In enlightenment, e/S as the authentic subject, which remains potential before enlightenment, is actualized or realized so that it understands itself as e/S, no more as the mere ego. In order for e/S to be realized and understand itself as e/S, egocentricity, egoism and the confusion of the verbalized reality with "reality as it is" must be overcome. This is the goal of religious practice. e/S From the point of view of interreligious dialogue,"Christ who lives in me" corresponds to "actualized Buddha-nature" or "the Formless Self" in Buddhist language, that is, the Self as we call it. 2 In the case of Paul,"Christ who lives in me" is the ultimate subject of him on the one hand, and "Christ the Son of God" is the object of his faith on the other (Gal. 2:19-20). That means: the ego of Paul that believes in the Son of God is borne by "Christ in me"; as Paul says, "Christ was revealed to and [End Page 95] in me" (Gal. 1:16). In this way, the subjectivity of Paul consists of e/S. Of S, namely, Paul is aware as e/S--neither as e, which is ignorant of S, nor as S. It is impossible for S to exist alone. Egocentricity and Egoism The distinction between e and e/S is of fundamental importance to our theme. e means in this essay the mere ego that is ignorant of S.When it becomes aware of S we represent it as the ego of e/S. e is egocentric and egoistic. It goes without saying that the ego-centered "I" driven by desires produces immorality and social anomies. The biblical word for this is sin, the transgression of the Law.But there is another problematic concerning e, namely egoism, which can be at work even in the effort to attain a high level of morality. We understand the egoistic ego as follows: the ego is to itself the only reality that concerns and moves it. It posits itself solely on itself apart from the relation to others and to S. By itself it projects itself and strives to realize itself. It can, among others, set up its own ideals and pursue their realization. It can, for example, conceive the moralistic ideal that seems to be the reverse of immorality and social anomie. Indeed, it can succeed in controlling egocentricity so that it seems to have attained perfect morality. In reality, it is interested only in its own moral perfection, not in the person encountered (moralistic egoism). Such e is illustrated in Luke 18:9-14 and described in Romans 7:7-24. Egoistic ego must die to itself and must be freed from egoism. (In Romans 6, for example, Paul does... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:A Short ReplyGianluca MoriWhile thanking Thomas Lennon for the interest he has shown in my work—and without going into details of interpretation which cannot bear discussion in this context—I would like to make a few remarks on factual questions raised by his response.1) Lennon's text (p. 338): "The text that Bayle and Mori erroneously take to be Saint-Evremond's is in fact from Jean-François Sarasin."While it is not certain (...) that Bayle and I "erroneously" take this text to be Saint-Evremond's, it is certain that Lennon erroneously takes it to be Sarasin's. In fact, the text quoted by Bayle is not taken from Sarasin's Discours sur Epicure, but, as Bayle explicitly points out ("Xénophanes," K, note 124), from a "Discours des ennuis et des déplaisirs." This "Discours" is chapter 5 of De l'usage de la vie, a text published in many editions of Saint-Evremond's works (see the Barbin 1692 in-4° ed., Seconde Partie, p. 326). The paternity of De l'usage de la vie is doubtful and controversial, but it possibly contains some passages taken from Saint-Evremond's unpublished manuscripts, especially in chapters 3-6, as reported by an important source quoted by Ternois in Saint-Evremond, Œuvres en prose, IV, 3-4, note 1.2) Lennon's text (pp. 338-39): "The significance of two of the other texts advanced by Mori is fully vitiated, for in them Bayle makes the same mistake."In my article, I did not fail to state that these texts (OD I, 158 and Dict., "Epicure," M) are taken from an apocryphal source. On page 329 I wrote: "[Bayle] mistakenly attributes to [Saint-Evremond] a text on Epicurus's morals [i.e., Sarasin's Discours] included in that volume." However, it was absolutely impossible, for seventeenth-century readers, to distinguish between Saint-Evremond's original and apocryphal texts: the author himself—as is widely known—did not want to clarify this point (with a few exceptions, including the Saint-Evremoniana, which, as we have seen, Bayle never attributed to Saint-Evremond). [End Page 343] And this is true for all editions: there is no significant difference between genuine and pirated editions, since no official edition, authorized and revised by the author, existed before Des Maizeaux's posthumous one. From this point of view, virtually nobody (before 1705) could "study" Saint-Evremond's texts. (On this connection it should be added that I never claimed that Bayle "studied" Saint-Evremond, but only that he read his available works and made up his mind on them, and particularly on the Conversation du Maréchal d'Hocquincourt—which should be at the core of the present debate—long before reading Cotolendi).3) Lennon's text (p. 336): "As Mori acknowledges elsewhere, Labrousse thinks Le Vassor was a left-wing Anglican who failed to understand Bayle's calvinist perspective."Concerning Le Vassor, I "acknowledge" Labrousse's opinion only to reject it with a detailed argument (Bayle philosophe, 262, note 341).Gianluca MoriUniversità del Piemonte OrientaleCopyright © 2004 The Journal of the History of Ideas, Inc.... (shrink)

São muitas as abordagens do fenômeno religioso surgidas nos últimos dois séculos. Algumas recorrem aos métodos elaborados pelas ciências humanas, sobretudo a historiografia, a sociologia, a etnologia/antropologia, a psicologia e a fenomenologia. Outras tratam a religião numa perspectiva filosófica, como se pode ver nos grandes autores que, sobretudo a partir do século XIX, se consagraram à elaboração de uma filosofia da religião. Nas últimas décadas, com a renovação da filosofia hermenêutica, novas leituras da religião têm surgido, renovando profundamente esse campo (...) do saber. O texto aqui proposto apresenta alguns elementos da grande síntese do filósofo luxemburguês Jean Greisch, pouco conhecido no Brasil, mas cuja contribuição ao estudo da religião é original, privilegiando uma hermenêutica da passagem. Após uma breve apresentação de sua obra consagrada à filosofia da religião, serão apresentados os cinco “paradigmas” dos estudos da religião segundo ele: o especulativo, o crítico, o fenomenológico, o analítico e o hermenêutico, o último seguido pelo próprio autor. (shrink)

L'impianto didattico di questa 'Storia' consente di: conciliare l'esposizione piana dei concetti con il rigore del linguaggio filosofico; favorire la percezione delle strutture concettuali, con il duplice scopo di illustrare adeguatamente sia l'impianto filosofico dei singoli autori sia lo sviluppo storico dei diversi problemi; presentare la storia del pensiero moderno in una chiave di categorie filosofiche, oltre che storico-evolutiva; delineare i contesti storici in cui nascono le diverse espressioni del pensiero moderno; rimarcare la diversità dei generi letterari utilizzati dagli autori, (...) mostrandone la connessione con il loro modo di filosofare. (shrink)

The fruit of a lifetime of study and contemplation, Seiichi Hatano's final work, Time and Eternity, develops most fully his tripartite scheme of temporality. For Hatano, one of the first Japanese philosophers to study the works of Western thinkers, human experience could be analyzed with reference to natural, cultural, and religious temporalities. Each temporal stage is further characterized by the type of love that rules at that level of life. In Time and Eternity, Hatano explores the stages of temporality (...) in depth and attempts to locate the kind of love which governs in each phase. (shrink)

H. Putnam has been considered the most Peircean philosopher among the neopragmatists. This note sugests that Putnam pays great atention to the problems Peirce tackled, but he does not share Peirce's thesis on the relation between "practical interests" and science. Therefore, Putnam's realism is more Deweyan and Jamesian than Peircean.