The study of the autonomic nervous system (ANS) function has shown to provide useful indicators for risk stratification and early detection on a variety of cardiovascular pathologies. However, data gathered during different tests of the ANS are difficult to analyse, mainly due to the complex mechanisms involved in the autonomic regulation of the cardiovascular system (CVS). Although model-based analysis of ANS data has been already proposed as a way to cope with this complexity, only a few models coupling the main (...) elements involved have been presented in the literature. In this paper, a new model of the CVS, representing the ventricles, the circulatory system and the regulation of the CVS activity by the ANS, is presented. The models of the vascular system and the ventricular activity have been developed using the Bond Graph formalism, as it proposes a unified representation for all energetic domains, facilitating the integration of mechanic and hydraulic phenomena. In order to take into account the electro-mechanical behaviour of both ventricles, an electrophysiologic model of the cardiac action potential, represented by a set of ordinary differential equations, has been integrated. The short-term ANS regulation of heart rate, cardiac contractility and peripheral vasoconstriction is represented by means of continuous transfer functions. These models, represented in different continuous formalisms, are coupled by using a multi-formalism simulation library. Results are presented for two different autonomic tests, namely the Tilt Test and the Valsalva Manoeuvre, by comparing real and simulated signals. (shrink)

The ventricular pressure profile is characteristic of the cardiac contraction progress and is useful to evaluate the cardiac performance. In this contribution, a tissue-level electromechanical model of the left ventricle is proposed, to assist the interpretation of left ventricular pressure waveforms. The left ventricle has been modeled as an ellipsoid composed of twelve mechano-hydraulic sub-systems. The asynchronous contraction of these twelve myocardial segments has been represented in order to reproduce a realistic pressure profiles. To take into account the different energy (...) domains involved, the tissue-level scale and to facilitate the building of a modular model, multiple formalisms have been used: Bond Graph formalism for the mechano-hydraulic aspects and cellular automata for the electrical activation. An experimental protocol has been defined to acquire ventricular pressure signals from three pigs, with different afterload conditions. Evolutionary Algorithms have been used to identify the model parameters in order to minimize the error between experimental and simulated ventricular pressure signals. Simulation results show that the model is able to reproduce experimental ventricular pressure. In addition, electro-mechanical activation times have been determined in the identification process. For example, the maximum electrical activation time is reached, respectively, 96.5, 139.3 and 131.5 ms for the first, second, and third pigs. These preliminary results are encouraging for the application of the model on non-invasive data like ECG, arterial pressure or myocardial strain. (shrink)

The study of the autonomic nervous system (ANS) function has shown to provide useful indicators for risk stratification and early detection on a variety of cardiovascular pathologies. However, data gathered during different tests of the ANS are difficult to analyse, mainly due to the complex mechanisms involved in the autonomic regulation of the cardiovascular system (CVS). Although model-based analysis of ANS data has been already proposed as a way to cope with this complexity, only a few models coupling the main (...) elements involved have been presented in the literature. In this paper, a new model of the CVS, representing the ventricles, the circulatory system and the regulation of the CVS activity by the ANS, is presented. The models of the vascular system and the ventricular activity have been developed using the Bond Graph formalism, as it proposes a unified representation for all energetic domains, facilitating the integration of mechanic and hydraulic phenomena. In order to take into account the electro-mechanical behaviour of both ventricles, an electrophysiologic model of the cardiac action potential, represented by a set of ordinary differential equations, has been integrated. The short-term ANS regulation of heart rate, cardiac contractility and peripheral vasoconstriction is represented by means of continuous transfer functions. These models, represented in different continuous formalisms, are coupled by using a multi-formalism simulation library. Results are presented for two different autonomic tests, namely the Tilt Test and the Valsalva Manoeuvre, by comparing real and simulated signals. (shrink)

The study of the autonomic nervous system (ANS) function has shown to provide useful indicators for risk stratification and early detection on a variety of cardiovascular pathologies. However, data gathered during different tests of the ANS are difficult to analyse, mainly due to the complex mechanisms involved in the autonomic regulation of the cardiovascular system (CVS). Although model-based analysis of ANS data has been already proposed as a way to cope with this complexity, only a few models coupling the main (...) elements involved have been presented in the literature. In this paper, a new model of the CVS, representing the ventricles, the circulatory system and the regulation of the CVS activity by the ANS, is presented. The models of the vascular system and the ventricular activity have been developed using the Bond Graph formalism, as it proposes a unified representation for all energetic domains, facilitating the integration of mechanic and hydraulic phenomena. In order to take into account the electro-mechanical behaviour of both ventricles, an electrophysiologic model of the cardiac action potential, represented by a set of ordinary differential equations, has been integrated. The short-term ANS regulation of heart rate, cardiac contractility and peripheral vasoconstriction is represented by means of continuous transfer functions. These models, represented in different continuous formalisms, are coupled by using a multi-formalism simulation library. Results are presented for two different autonomic tests, namely the Tilt Test and the Valsalva Manoeuvre, by comparing real and simulated signals. (shrink)

The ventricular pressure profile is characteristic of the cardiac contraction progress and is useful to evaluate the cardiac performance. In this contribution, a tissue-level electromechanical model of the left ventricle is proposed, to assist the interpretation of left ventricular pressure waveforms. The left ventricle has been modeled as an ellipsoid composed of twelve mechano-hydraulic sub-systems. The asynchronous contraction of these twelve myocardial segments has been represented in order to reproduce a realistic pressure profiles. To take into account the different energy (...) domains involved, the tissue-level scale and to facilitate the building of a modular model, multiple formalisms have been used: Bond Graph formalism for the mechano-hydraulic aspects and cellular automata for the electrical activation. An experimental protocol has been defined to acquire ventricular pressure signals from three pigs, with different afterload conditions. Evolutionary Algorithms have been used to identify the model parameters in order to minimize the error between experimental and simulated ventricular pressure signals. Simulation results show that the model is able to reproduce experimental ventricular pressure. In addition, electro-mechanical activation times have been determined in the identification process. For example, the maximum electrical activation time is reached, respectively, 96.5, 139.3 and 131.5 ms for the first, second, and third pigs. These preliminary results are encouraging for the application of the model on non-invasive data like ECG, arterial pressure or myocardial strain. (shrink)

Zudem kommen neben Uninteressierten (Descartes, Kant) auch Kritiker der Tradition (Nietzsche, Heidegger) zu Wort. Die Rolle der Wahrheit in Politik, Recht und Theologie wird im Blick gehalten.

B. Readings (University in Ruins. Cambridge: Harvard University Press, 1996) argued that universities have abandoned their original project of promoting a national culture and have tried to substitute by embracing globalization, but the vagueness and incoherence of the concept has failed to return purpose to the University. The academic treatment of corporate social responsibility illustrates this dilemma. For a generation after H.R. Bowen (Social Responsibilities of the Businessman. New York: Harper & Row, 1953) founded the field, scholars struggled to fit (...) the concept within a national system of pluralistic power-sharing among a variety of institutions that would define and enforce standards of responsibility necessary for the general good of American society. That understanding changed in the nineteen eighties, shortly after corporate executives had united to an unprecedented degree to direct the power of government in their interests, influence the public agenda, and roll back the power of unions. In response, business ethicists began to reformulate corporate social responsibility as a voluntary practice on the part of these same executives. Since the Kantian and Lockean principles upon which this approach was based were themselves problematic, it is not surprising that the experience gained over the last generation casts doubt on the efficacy of this reliance on voluntary restraint and personal initiative. However, circumstances that include the failure of globalization to deliver on its promises may have changed sufficiently in recent years to revive interest in approaches that acknowledge the importance of countervailing power for encouraging greater corporate social responsibility. (shrink)

Music is fundamental to human existence, a cultural universal among all humans for all times. It is embedded in our evolution, encoded in our DNA, which is to say, essential to our survival. Academics in a variety of disciplines have considered this idea to devise explanations that Richard Manning, a lifelong journalist, finds hollow, arcane, incomplete, ivory-towered, and just plain wrong. He approaches the question from a wholly different angle, using his own guitar and banjo as instruments of discovery. (...) In the process, he finds himself dancing in celebration of music rough and rowdy. American roots music is not a product of an elite leisure class, as some academics contend, but of explosive creativity among slaves, hillbillies, fieldhands, drunks, slackers, and hucksters. Yet these people-poor, working people-built the foundations of jazz, gospel, blues, bluegrass, rock 'n' roll, and country music, an unparalleled burst of invention. This is the counterfactual to the academics' story. This is what tells us music is essential, but by pulling this thread, Manning takes us down a long, strange path, following music to deeper understandings of racism, slavery, inequality, meditation, addiction, the science of our brains, and ultimately to an enticing glimpse of pure religion. Use this book to follow where his guitar leads. Ultimately it sings the American body, electric. (shrink)

ZusammenfassungObwohl Edward Saids Einfluss auf die Nahoststudien, und darüber hinaus auf die Sozial-, Geistes- und Kulturwissenschaften, aus vielen Perspektiven als glänzender Triumph oder als Tragödie betrachtet worden ist, stellen nur wenige die erstaunliche Reichweite und Durschlagskraft seines Werks Orientalismus in der akademischen Welt in Frage. Ich möchte hier die Rolle Saids sowie die durch seine Arbeiten beförderte postkoloniale Lehrmeinung untersuchen, mithin auch die Art und Weise, wie der Westen bisher mit dem geistigen Krieg umgeht, den triumphalistische MuslimeEine Bemerkung zum (...) Triumphalismus. Das ist eine ungebräuchliche Bezeichnung derjenigen, die glauben, ihre Gruppe sei allen anderen überlegen und solle zum Beweis ihrer Überlegenheit über diese herrschen: „Wir haben recht, unser Glaube ist wahr, weil wir über euch triumphieren werden.“ In Bezug auf den Islam ist damit eine Form der Religiosität gemeint, die glaubt, es sei ihre Bestimmung, die ganze Welt Allahs Willen zu unterwerfen; die Welt sei geteilt in den Dar al-Harb und den Dar al-Islam und dieser solle jenen ersetzen; im Idealfall stellten die Muslime die Ungläubigen vor die Wahl zwischen Konversion, Tod und Unterordnung. Moderne Demokratien, die auf der Trennung von Kirche und Staat beruhen, erfordern eine offizielle Absage an triumphalistische Religiosität. mit dem erklärten Ziel führen, demokratischen Verfassungen den Dar al-Islam zu oktroyieren. (shrink)

Richard McCormick examines the concepts of postmodernity and postmodernism as they apply to West Germany, discussing them against the background of cultural and political upheaval in that country since the 1960s, rather than exclusively in the more familiar setting of intellectual history. Considering six literary and cinematic texts that are marked by a preoccupation with the self and subjectivity, he underscores the crucial influence of feminism on writers and filmmakers--and on the "postmodern." In a broad international context he describes (...) the conflicting forces that affected the West German student movementthe rationalistic tradition of the Weimar Left and more "irrational" influences such as French existentialism and surrealism (as well as the American "Beat" movement and rock & roll)--and shows how these forces played themselves out so that dogmatic Marxist Leninism was repudiated in favor of a "New Subjectivity.". At the center of the discussion are the novels Lenz by Peter Schneider, Class Love (Klassenliebe) by Karin Struck, and Devotion by Botho Strauss, and the films Wrong Move written by Peter Handke and directed by Wim Wenders, Germany, Pale Mother by Helma Sanders-Brahms, and The Subjective Factor by Helke Sander. The author shows how ongoing attempts to attack the separation of emotion from reason, life from art, the private from the public, and the personal from the political brought about changes in outlook, from the 1960s to the early 1980s, that are related to the rise of new political movements--ecology, nuclear disarmament, and feminism. Originally published in 1991. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905. (shrink)

Mit diesem Buch führt Richard Egger in das komplexe Thema Ethik ein: in die Theorie der Menschlichkeit. Er richtet sich damit an Menschen, die Verantwortung für andere tragen – sei es als Vorgesetzte, als Ärztin oder Wissenschaftler, Mutter oder Vater, Lehrer oder in vielen anderen Rollen. Anhand von Beispielen aus unterschiedlichen Lebensbereichen zeigt Egger auf, welche Rolle Vernunft und Gefühl, aber auch unsere Gerechtigkeitsvorstellung für ethisches Handeln spielen. Sein Fazit: Menschlich handeln kann nur, wer einen Sinn für Fairness (...) und Gleichwertigkeit, persönliche Verpflichtung und moralische Integrität entwickelt. Eine solche Haltung durchdringt den ganzen Menschen und macht Verantwortungsträger erst zu wirklichen Leadern.Egger stützt sich dabei auf die Fragen und Argumente, Regeln und Instrumente aus der Geschichte der Ethik, aber auch auf seine langjährige Erfahrung als Berater von Menschen. Der Autor schreibt philosophisch fundiert und gleichzeitig fesselnd und verständlich. Der Inhalt Die Welt: Warum wir Ethik brauchen Regeln: Wie Ethik funktioniert Sie: Was Ethik aus Ihnen macht Natur: Wie Ethik sich ins Ganze fügt. (shrink)

In this paper, we endeavour to give a historically accurate presentation of how Leibniz understood his infinitesimals, and how he justified their use. Some authors claim that when Leibniz called them “fictions” in response to the criticisms of the calculus by Rolle and others at the turn of the century, he had in mind a different meaning of “fiction” than in his earlier work, involving a commitment to their existence as non-Archimedean elements of the continuum. Against this, we show (...) that by 1676 Leibniz had already developed an interpretation from which he never wavered, according to which infinitesimals, like infinite wholes, cannot be regarded as existing because their concepts entail contradictions, even though they may be used as if they exist under certain specified conditions—a conception he later characterized as “syncategorematic”. Thus, one cannot infer the existence of infinitesimals from their successful use. By a detailed analysis of Leibniz’s arguments in his De quadratura of 1675–1676, we show that Leibniz had already presented there two strategies for presenting infinitesimalist methods, one in which one uses finite quantities that can be made as small as necessary in order for the error to be smaller than can be assigned, and thus zero; and another “direct” method in which the infinite and infinitely small are introduced by a fiction analogous to imaginary roots in algebra, and to points at infinity in projective geometry. We then show how in his mature papers the latter strategy, now articulated as based on the Law of Continuity, is presented to critics of the calculus as being equally constitutive for the foundations of algebra and geometry and also as being provably rigorous according to the accepted standards in keeping with the Archimedean axiom. (shrink)

This infamous book has enjoyed a lively underground reputation since its first publication in 1970. Richard Meltzer (a.k.a. R. Meltzer) took his training as a young philosopher and applied it with unalloyed enthusiasm to the lyrics, sound, and culture of rock and roll. Never before had anyone noticed the relationship between the philosophy of Heidegger and a tune by Little Anthony and the Imperials, heard the cries of agony in the Shangri Las' “Remember (Walkin' in the Sand)”, or transcribed (...) every "papa-ooma-mow-mow" in the Trashmen's “Surfin' Bird.”From Dionne Warwick to Plato, Jim Morrison to Bert Brecht, Conway Twitty to Miguel de Unamuno, Meltzer subverts high and low culture in his search for meaning, emotion, and codes in popular music. At once an earnest investigation and a crypto put-on, the book can be read for its nuggets of information and insights or for its humor. Here with Greil Marcus's new introduction, yet another generation of readers can be outraged and inspired. (shrink)

Although caution ought to be exercised when it comes to his retrospective assessment of his past works, Nietzsche’s EH accurately describes D as a significant beginning, and a preparatory work. The preparation in question is for a broad critical reappraisal of the function of morality. More specifically, the object of Nietzsche’s critique is that which he titles “customary morality.” It is D that got the ball rolling on this project, as well as on many familiar Nietzschean themes that find arguably (...) maturer exposition in later works, those more systematically studied on university syllabi. In this respect and others, Keith Ansell-Pearson and Rebecca Bamford are justified in their claim that D itself is a significant... (shrink)

ZusammenfassungEs werden zwei Begriffe, «Prozess» und «Funktion», besprochen, welche in der heutigen Philosophie zu Grundbegriffen zweier, miteinander unvereinbarer philosophischer Systeme geworden sind, die sich beide auf die Wissenschaft stützen. In dieser hingegen werden die beiden genannten Begriffe nicht als einander ausschliessend angesehen, sondern funktionieren als Leitbegriffe zweier nebeneinder stehenden Hypothesen, welche zu verschiedenen Methoden der Forschung führen. Im ersten Teil des vorliegenden Aufsatzes wird der Begriff «Prozess» im Hinblick auf die gegenwärtige Physik untersucht und vier Grundstellungen unterschieden, die sich in (...) der Relativitätstheorie Whiteheads, in der Einsteinschen einheitlichen Feldtheorie, in der mit dieser unvereinbaren Auffassung der führenden Quantenphysiker und dem Bridgmanschen Operationismus ausprägen. Im zweiten Teil wird der Begriff «Funktion» im Hinblick auf die heutige Biologie erörtert. Die beiden oben erwähnten philosophischen Systeme zeigen aber, dass philosophisch Funktionen als Prozesse und umgekehrt Prozesse als Funktionen aufgefasst werden können. Andererseits beeinflusst jeder Begriff von «Prozess», der in der Physik entwickelt wird, die Biologie und jeder Begriff von «Funktion», der in der Biologie auftritt, hat Bedeutung für die Physik. Im Grunde genommen, sind die beiden genannten Begriffe die Grenzpunkte des Weges, den die Entwicklung der, aus der antiken Philosophie stammenden Begriffe «Sein» und «Substanz» genommen hat. Beide haben ihre berechtigte methodische Verwendung in der Wissenschaft. Vielleicht könnte die Philosophie, deren Grundfragen in den Wissenschaften eine fundamentale Rolle spielen, aus diesem Vorgehen der Wissenschaften lernen, ihre Begriffe genauer zu präzisieren, indem sie, statt ihre Thesen zu verabsolutieren, diese als Forschungshypothesen auffasst, deren Folgen zu untersuchen sind. Auch könnte man auf diese Weise dazu kommen, die philosophischen Thesen nicht als absolute, ausschliessende Gegensätze, sondern als «komplementär» aufzufassen und diese «komplementären» Gesichtspunkte für die wissenschaftliche Forschung auszuwerten. (shrink)

Dieser Band ist eine Sammlung von Vortragen, die auf einer Tagung mit dem Titel "Aktuelle Probleme der Philosophie der Wahrnehmung" gehalten wurden, die im Sommer 2007 an der Universitat Siegen stattfand. Der Band verfolgt das Ziel, den Reichtum und die Lebendigkeit von wichtigen gegenwartigen Debatten in der Philosophie der Wahrnehmung zu dokumentieren. Die Philosophie der Wahrnehmung spielt in verschiedenen philosophischen Kerndisziplinen-in der Metaphysik, in der Erkenntnistheorie, in der Philosophie des Geistes-eine ganz wesentliche Rolle. Die in diesem Band versammelten Aufsatze (...) beschaftigen sich mit zentralen Aspekten grundlegender philosophischer Fragestellungen dieser Kerndisziplinen.". (shrink)

In a recent issue of Journal of Medical Ethics, we discussed the ethical review of evaluations of interventions that would occur whether or not the evaluation was taking place. We concluded that standard research ethics frameworks including the Ottawa Statement, which requires justification for all aspects of an intervention and its roll-out, were a poor guide in this area. We proposed that a consideration of researcher responsibility, based on the consequences of the research taking place, would be a more appropriate (...) way delineate the scope of research ethics review. Weijer and Taljaard present a counterargument to our proposal, which we address in this reply. They claim that a focus on researcher responsibility will weaken the protection of research participants and link it to ‘unethical research’ and a ‘government experimenting on its own people’. However, the moral responsibility of researchers is defined in terms of the consequences of the research on human welfare and harm, not in opposition to it. Weijer and Taljaard argue that researchers must justify what they are studying whether or not they have any control over it and that governments must justify their programmes, including by demonstrating equipoise, to a research ethics committee if they implement them in a randomised way. We strongly disagree that this is a defensible way to define the scope of research ethics review and argue that this provides no further protections to research participants beyond what we propose, but places a potential barrier to learning from government programmes. (shrink)

Rolling Stones guitarist Keith Richards has argued that rock and roll happens from the neck down. In this contribution to The Rolling Stones and Philosophy, edited by Luke Dick and George Reisch, I draw on neuroscience to argue that, in the parlance of John Stuart Mill, rock and roll is both a higher and a lower pleasure.

From their commanding role in the so-called British Invasion of the early 1960s to their status as the elder statesmen of rock and roll, the Stones have become more than an evanescent phenomenon in pop culture. They have become a touchstone not only for the history of our times?their performance at the Altamont Raceway marked the "end of the sixties," while their 1990 concert in Prague helped Czechoslovakia and other eastern bloc nations celebrate their newfound freedom out from under Moscow's (...) thumb. Because of their longevity, the music and career of the Stones?much more than The Beatles?stand as touchstones in the personal lives of even casual Stones fans. Everyone of a certain age remembers the Stones on Ed Sullivan, the death of founder Brian Jones, their favorite songs, concerts, or videos, and their stance in the classic?Beatles versus Stones” debates. In the wake of Keith Richards's bestselling autobiography, Life, many are now reliving these events and decades from the viewpoint of the band's endearing and seemingly death-defying guitarist. The chapters in The Rolling Stones and Philosophy celebrate the Stones' place in our lives by digging into the controversies, the symbols, and meanings the band and its songs have for so many. What might you mean by?sympathy for the Devil”? Did the Stones share any of the blame for the deaths at Altamont, as critic Lester Bangs charged they did in Rolling Stone magazine? What theories of ethics and personality lay behind the good-boy image of the Beatles and the bad-boy reputation the Stones acquired? If Keith Richards really had his blood replaced four separate times, does that make him a zombie? How do the Glimmer Twins help us refine our understanding of friendship? Written by a dozen philosophers and scholars who adore the Rolling Stones not only for their music, this book will become required reading for anyone seeking maximum satisfaction from "the world's greatest rock and roll band.". (shrink)

Bei der Renaissance der philosophischen Auseinandersetzung mit Fragen über Gott spielte der Oxforder Philosoph Richard Swinburne eine wesentliche Rolle. Er kann als der bedeutendste zeitgenössische Vertreter der natürlichen Theologie gelten. Natürliche Theologie ist das Unternehmen, philosophisch zu untersuchen, ob es einen Gott gibt und wie er beschaffen ist. Dies ›philosophisch‹ und nicht theologisch zu untersuchen, heißt, direkte Offenbarung dabei nicht als Erkenntnisquelle zu verwenden.

A selection of speeches and essays from the author's second decade as president of Yale University.

Das Hauptziel des Aufsatzes ist es, die Polemik Richard Shustermans gegen Richard Rorty über die nicht-diskursive Erfahrung und ihre Rolle in der Philosophie John Deweys sowohl kritisch zu interpretieren als auch darzustellen, auf welche Weise diese Debatte Shusterman zur Begründung einer neuen philosophischen Disziplin, die er „Somästhetik“ nennt, führt. Im ersten Teil wird Folgendes analysiert: Shustermans Kritik an dem „globalen Textualismus“ Rortys; Shustermans Auffassung von Deweys Theorie der Erfahrung. Im weiteren Teil wird die Somästhetik synthetisch dargelegt.

The discussion of good and evil must not be confined to the sterile lecture halls of academics but related instead to ordinary human feelings, needs, and desires, says noted philosopher Richard Taylor. Efforts to understand morality by exploring human reason will always fail because we are creatures of desire as well. All morality arises from our intense and inescapable longing. The distinction between good and evil is always clouded by rationalists who convert the real problems of ethics into complex (...) philosophical puzzles. In the first part of Good and Evil, Taylor looks for a more meaningful conception by reexamining and rejecting the whole rationalistic tradition that dominates philosophical ethics. The second part provides an empirical explanation of good and evil, noting that one does not have to look too far to find prime examples of the failure of fixed moral rules. Including important commentary on Joseph Fletcher's groundbreaking situation ethics, and Aristotle's virtues (e.g., magnanimity and pride), Taylor rounds out the book by developing a philosophy of aspiration--personal worth as an ethical ideal--to replace the morality of duty. He offers a modified form of situation ethics to fit the contemporary problems we face. (shrink)

Orientalism and Religion offers us a timely discussion of the implications of contemporary post-colonial theory for the study of religion. Drawing on a variety of post-structuralist and post-colonial thinkers, including Foucault, Gadamer, Said, and Spivak, Richard King examines the way in which notions such as mysticism, religion, Hinduism and Buddhism are taken for granted, and shows us how religion needs to be redescribed along the lines of cultural studies.

This is the third edition of a classic book first published in 1960, which has sold thousands of copies in two paperback edition and has been translated into several foreign languages. Popkin's work ha generated innumerable citations, and remains a valuable stimulus to current historical research. In this updated version, he has revised and expanded throughout, and has added three new chapters, one on Savonarola, one on Henry More and Ralph Cudworth, and one on Pascal. This authoritative treatment of the (...) theme of scepticism and its historical impact will appeal to scholars and students of early modern history now as much as ever. (shrink)