In Dependent Rational Animals, Alasdair MacIntyre attempts to ground the virtues in a biological account of humans. Drawing from this attempt, he also tries to answer the question of why we should care for the severely disabled. MacIntyre’s difficulty in answering this question begins with the fact that his communities of practices do not naturally include the severely disabled within their membership and care. In response to this difficulty, he provides four reasons for why we should care for the severely (...) disabled. I argue that three of these reasons are inadequate, and that the fourth is incomplete although it does point in a promising direction. I conclude that a more satisfactory answer requires a further extension of the central development from After Virtue to Dependent Rational Animals, and I draw from Wendell Berry, whose work MacIntyre admires, to provide an illuminating illustration of what such an answer might look like. (shrink)

On the standard simple foundationalist interpretation of Thomas Reid’s epistemology, his epistemic appeals to God seem problematic. These appeals are generally dismissed as dogmatic, viciously circular, or mere irrelevant pieties. This chapter responds first that, even on the standard foundationalist interpretation, theism can sometimes boost the epistemic justification of first principles. It then argues that Reid’s epistemology is plausibly interpreted as containing coherentist strands. While not generally necessary for knowledge, coherence can boost the justification of our basic beliefs, and this (...) boost in justification can be valuable in certain contexts. Because many of Reid’s epistemic appeals to God—including those that are viciously circular on the standard interpretation—are coherence-generating, this interpretation provides a plausible explanation for how theism can boost the justification of various first principles, including first principles about the reliability of our faculties. (shrink)

Quarterly publication discussing various topics in environmental ethics, including features, discussion papers, book reviews, editorial commentaries, and other text related to environmental philosophies. Some issues also include announcements and other news related to the environmental studies community.

The role of theism in Thomas Reid’s epistemology remains an unresolved question. Opinions range from outright denials that theism has any relevance to Reid’s epistemology to claims that Reid’s epistemology depends upon theism in a dogmatic or a viciously circular manner. This dissertation attempts to bring some order to this interpretive fray by answering the following question: What role or roles does theism play in Reid’s epistemology, particularly in relation to the epistemic justification of first principles? Chapters 2-4 lay the (...) foundation for answering this question and clarify some terminology. Chapter 2 distinguishes key senses in which Reid uses the terms “principle” and “first principle.” Chapter 3 argues for a novel interpretation of common sense and the principles of common sense. This interpretation avoids a number of objections to Reid’s principles of common sense. Chapter 4 considers the initial externalist justification of Reid’s first principles. It shows Reid has a surprisingly well-developed proper-functionalism and brings to light several overlooked elements of his epistemology. Chapters 5-8 argue theism can and does play various important and philosophically respectable roles in Reid’s epistemology, particularly in relation to the justification of first principles. Chapter 5 argues that even on the standard foundationalist interpretation of Reid’s epistemology, theism can and does boost the justification of first principles. Chapter 6 shows Reid’s epistemology is not a form of simple foundationalism but contains coherentist elements. This enables theism further to boost the justification of first principles. Chapter 7 reveals that Reid’s epistemology contains different kinds or levels of knowledge, and shows that theism enables the highest form of knowledge, which I call scientia. Chapter 8 argues that within Reid’s epistemology theism helps protect and preserve the justification of first principles. (shrink)

Rosłanowski and Shelah [Small-large subgroups of the reals, Math. Slov. 68 473–484] asked whether every locally compact non-discrete group has a null but non-meager subgroup, and converse...

The presence and role of microbes in human cancers has come full circle in the last century. Tumors are no longer considered aseptic, but implications for cancer biology and oncology remain underappreciated. Opportunities to identify and build translational diagnostics, prognostics, and therapeutics that exploit cancer's second genome—the metagenome—are manifold, but require careful consideration of microbial experimental idiosyncrasies that are distinct from host‐centric methods. Furthermore, the discoveries of intracellular and intra‐metastatic cancer bacteria necessitate fundamental changes in describing clonal evolution and selection, (...) reflecting bidirectional interactions with non‐human residents. Reconsidering cancer clonality as a multispecies process similarly holds key implications for understanding metastasis and prognosing therapeutic resistance while providing rational guidance for the next generation of bacterial cancer therapies. Guided by these new findings and challenges, this Review describes opportunities to exploit cancer's metagenome in oncology and proposes an evolutionary framework as a first step towards modeling multispecies cancer clonality. Also see the video abstract here: https://youtu.be/-WDtIRJYZSs. (shrink)

Rosłanowski and Shelah [Small-large subgroups of the reals, Math. Slov. 68(3) (2018) 473–484] asked whether every locally compact non-discrete group has a null but non-meager subgroup, and conversely, whether it is consistent with [Formula: see text] that in every locally compact group a meager subgroup is always null. They gave affirmative answers for both questions in the case of the Cantor group and the reals. In this paper, we give affirmative answers for the general case.

Reading and reflecting on real cases helps ethics come alive for students. Good cases grip our attention, engage our imagination, and show the real-life implications of abstract ethical theories, ideals, commitments, and policies. Finding good case studies is both difficult and time-consuming for instructors, so I was excited to learn about Glenn McGee’s book Bioethics for Beginners: 60 Cases and Cautions from the Moral Frontier of Healthcare. According to the publisher, its target audiences are “courses in bioethics, medical ethics, and (...) applied ethics.” The book sounded promising.McGee’s book contains ten chapters, or “cautions,” plus a conclusion. Each chapter consists of anywhere from three to nine loosely associated “cases.” The cases average about one and a half pages each, but they vary significantly in length. The shortest cases are less than a page while the longest is twelve pages .All sixty cases, as well as the two sections that compose the conclus .. (shrink)

The quality of the educational experience for students may be at risk if they are not taught in ways that are effective and pertinent. While educational institutions (administrators, faculty senates or a combination) may try to compel faculty members to gain knowledge of and utilize up-to-date learning and instructional design strategies, these faculty members may baulk at this mandate, citing academic freedom as their right to design their courses in any way they see fit. Following is a discussion exploring the (...) issue, suggesting that regardless of how academic freedom is interpreted, faculty members have an ethical obligation to deliver instruction in ways that do not violate students' rights to learn. Consequently, institutions have a right as well as a duty to compel their faculty members to follow through with this obligation. (shrink)

We are interested in the possible sets of cardinalities of branches of Kurepa trees in models of ZFC \ CH. In this paper we present a sufficient condition to be consistently the set of cardinalities of branches of Kurepa trees.

The unexpected roles of the microbiota in cancer challenge explanations of carcinogenesis that focus on tumor-intrinsic properties. Most tumors contain bacteria and viruses, and the host’s proximal and distal microbiota influence both cancer incidence and therapeutic responsiveness. Continuing the history of cancer–microbe research, these findings raise a key question: to what extent is the microbiota relevant for clinical oncology? We approach this by critically evaluating three issues: how the microbiota provides a predictive biomarker of cancer growth and therapeutic responsiveness, the (...) microbiota’s causal role(s) in cancer development, and how therapeutic manipulations of the microbiota improve patient outcomes in cancer. Clarifying the conceptual and empirical aspects of the cancer-associated microbiota can orient future research and guide its implementation in clinical oncology. (shrink)

We provide self-contained proof of a theorem relating probabilistic coherence of forecasts to their non-domination by rival forecasts with respect to any proper scoring rule. The theorem recapitulates insights achieved by other investigators, and clarifi es the connection of coherence and proper scoring rules to Bregman divergence.

Cancers rely on multiple, heterogeneous processes at different scales, pertaining to many biomedical fields. Therefore, understanding cancer is necessarily an interdisciplinary task that requires placing specialised experimental and clinical research into a broader conceptual, theoretical, and methodological framework. Without such a framework, oncology will collect piecemeal results, with scant dialogue between the different scientific communities studying cancer. We argue that one important way forward in service of a more successful dialogue is through greater integration of applied sciences (experimental and clinical) (...) with conceptual and theoretical approaches, informed by philosophical methods. By way of illustration, we explore six central themes: (i) the role of mutations in cancer; (ii) the clonal evolution of cancer cells; (iii) the relationship between cancer and multicellularity; (iv) the tumour microenvironment; (v) the immune system; and (vi) stem cells. In each case, we examine open questions in the scientific literature through a philosophical methodology and show the benefit of such a synergy for the scientific and medical understanding of cancer. (shrink)

We consider a real-valued function f defined on the set of infinite branches X of a countably branching pruned tree T. The function f is said to be a limsup function if there is a function $u \colon T \to \mathbb {R}$ such that $f(x) = \limsup _{t \to \infty } u(x_{0},\dots,x_{t})$ for each $x \in X$. We study a game characterization of limsup functions, as well as a novel game characterization of functions of Baire class 1.

An absolute decline in US life expectancy in low education whites has alarmed policy makers and attracted media attention. Depending on which studies are correct, low education white women have lost between 3 and 5 years of lifespan; men, between 6 months and 3 years. Although absolute declines in life expectancy are relatively rare, some commentators see the public alarm as reflecting a racist concern for white lives over black ones. How ought we ethically to evaluate this lifespan contraction in (...) low education whites? Should we care, or is it racist to care? Does it constitute an injustice or reflect justice being done? I argue that the lifespan contraction in low education whites violates key normative criteria used to make determinations of health justice, and that these judgments do not vitiate concerns about racism. I conclude with reflections on US population health policy and building an inclusive health equity movement. (shrink)

The rise of neuroplasticity has led to new fields of study about the relation between social inequalities and neurobiology, including investigations into the “neuroscience of poverty.” The neural phenotype of poverty proposed in recent neuroscientific research emerges out of classed, gendered, and racialized inequalities that not only affect bodies in material ways but also shape scientific understandings of difference. An intersectional, sociomaterial approach is needed to grasp the implications of neuroscientific research that aims to both produce and repair neurobiological difference. (...) Following Benjamin’s critique of the “carceral imagination” of technoscience, this article considers how such research may fix in terms of helping, or in contrast, fix by classifying and reifying, vulnerable subjects. I address the potential for biosocial determinism in linking neural phenotypes and social problems. I use an intersectional approach to consider the presence and absence of race in this body of research and explore how some methodological and conceptual framings of the “brain on poverty” mark poor and minority children for intervention in concert with neoliberal approaches to poverty. (shrink)

Political philosophers’ prescriptions for poverty alleviation have overlooked the importance of social movements led by, and for, the poor in the global South. I argue that these movements are normatively and politically significant for poverty reduction strategies and global justice generally. While often excluded from formal political processes, organized poor communities nonetheless lay the groundwork for more radical, pro-poor forms of change through their grassroots resistance and organizing. Poor-led social movements politicize poverty by insisting that, fundamentally, it is caused by (...) social relations of power that exploit and subordinate poor populations. These movements and their organizations also develop the collective capabilities of poor communities in ways that help them to contest the structures and processes that perpetuate their needs deprivation. I illustrate these contributions through a discussion of the Landless Rural Worker’s Movement in Brazil, a poor mobilization organization in Bangladesh, and the slum and pavement dweller movement in India. Global justice theorizing about poverty cannot just “add on” the contributions of such struggles to existing analyses of, and remedies for, poverty, however; rather, we will need to shift to a relational approach to poverty in order to see the vital importance of organized poor communities to transformative, poor-centered poverty reduction. (shrink)

ABSTRACT:We extend the Base of the Pyramid (BoP) poverty-alleviation approach by recognizing the poor as valuable suppliers—specifically of intellectual property. Although the poor possess huge reserves of intellectual property, they are unable to participate in global knowledge networks owing to their illiteracy and poverty. This is a crippling form of social exclusion in today’s growing knowledge economy because it adversely affects their capabilities for advancement at several levels. Providing the poor access to global knowledge networks as rightful participants—as suppliers of (...) intellectual property—leads to poverty alleviation as a result of their increased social inclusion, not only through economic benefits, but also through the poor’s improved well-being as a result of their increased self-esteem and dignity. Using concepts from social network theory, we develop a poverty-alleviation approach to harness and integrate the intellectual property of the poor into global knowledge networks through trust-based partnerships among the poor, non-governmental organizations, and multinational corporations. (shrink)

Schooling Poor Minority Children: New Segregation in the Post-Brown Era explores the "redesign of school segregation" and explains why resegregation of schools in the post-Brown era is so destructive for poor minority students.

I hope to show that supervenience and determination, as I have here intuitively characterized them, are really different expressions of the same core idea which one may make more precise in a great number of different ways, depending on the interpretation one puts on the catchall parameters “cases”, “truth of kind P”and “truth of kind S”.

This book, now open-access from OUP, develops a normative theory of political responsibility for solidarity with poor populations by engaging closely with empirical studies of poor-led social movements in the Global South. Monique Deveaux rejects familiar ethical framings of problems of poverty and inequality by arguing that normative thinking about antipoverty remedies needs to engage closely with the aims, insights, and actions of “pro-poor,” poor-led social movements. Defending the idea of a political responsibility for solidarity, nonpoor outsiders—individuals, institutions, and states—can (...) help to advance a transformative anti-poverty agenda only by supporting the efforts of these movements. (shrink)

In their paper, ‘When are thought experiments poor ones?’ (Peijnenburg and Atkinson 2003), Jeanne Peijnenburg and David Atkinson argue that most, if not all, philosophical thought experiments are “poor” ones with “disastrous consequences” and that they share the property of being poor with some (but not all) scientific thought experiments. Noting that unlike philosophy, the sciences have the resources to avoid the disastrous consequences, Peijnenburg and Atkinson come to the conclusion that the use of thought experiments in science is in (...) general more successful than in philosophy and that instead of concocting more “recherché” thought experiments, philosophy should try to be more empirical. (shrink)

The creation of algebraic topology required “all the energy and the temperament of Emmy Noether” according to topologists Paul Alexandroff and Heinz Hopf. Alexandroff stressed Noether's radical pro-Russian politics, which her colleagues found in “poor taste”; yet he found “a bright trait of character.” She joined the Independent Social Democrats in 1919. They were tiny in Göttingen until that year when their vote soared as they called for a dictatorship of the proletariat. The Minister of the Army and many Göttingen (...) students called them Bolshevist terrorists. Noether's colleague Richard Courant criticized USPD radicalism. Her colleague Hermann Weyl downplayed her radicalism and that view remains influential but the evidence favors Alexandroff. Weyl was ambivalent in parallel ways about her mathematics and her politics. He deeply admired her yet he found her abstractness and her politics excessive and even dangerous. (shrink)

Incentive schemes, which offer recipients benefits if they meet particular requirements, are being used across the world to encourage healthier behaviours. From the perspective of equality, an important concern about such schemes is that since people often do not have equal opportunity to fulfil the stipulated conditions, incentives create opportunity for further unfair advantage. Are incentive schemes that are available only to disadvantaged groups less susceptible to such egalitarian concerns? While targeted schemes may at first glance seem well placed to (...) help improve outcomes among disadvantaged groups and thus reduce inequalities, I argue in this paper that they are susceptible to significant problems. At the same time, incentive schemes may be less problematic when they operate in ways that differ from the ‘standard’ incentive mechanism; I discuss three such mechanisms. (shrink)

In order to operate effectively, modern capitalism depends on agents who evince a rather morally undemanding type of moral character; one that is acquisitive, pecuniary, recognition-seeking and merely prudent. Adam Smith is considered to have been the key legitimiser of this archetype. In this paper I respond to the view that Smith is actually sceptical about the value of material acquisition and explore whether he really believed that the pursuit of tranquillity and virtue—especially beneficence—offers a superior route to happiness than (...) the commercial world of materialist acquisition. I approach these issues partly by considering the roles of beneficence and sympathy in Smith's system and partly by analysing the story of ‘The Poor Man's Son’ related in Book IV of The Theory of Moral Sentiments. As he narrates this story, Smith seems highly critical of the unrelenting drive for worldly success. But what is the real moral of the story? Should people contain their ambition for recognition and material succe... (shrink)

In their paper, 'When are thought experiments poor ones?' (Peijnenburg and Atkinson, 2003, Journal of General Philosophy of Science 34, 305-322), Jeanne Peijnenburg and David Atkinson argue that most, if not all, philosophical thought experiments are "poor" ones with "disastrous consequences" and that they share the property of being poor with some (but not all) scientific thought experiments. Noting that unlike philosophy, the sciences have the resources to avoid the disastrous consequences, Peijnenburg and Atkinson come to the conclusion that the (...) use of thought experiments in science is in general more successful than in philosophy and that instead of concocting more "recherché" thought experiments, philosophy should try to be more empirical. In this comment I will argue that Peijnenburg's and Atkinson's view on thought experiments is based on a misleading characterization of both, the dialectical situation in philosophy as well as the history of physics. By giving an adequate account of what the Discussion in contemporary philosophy is about, we will arrive at a considerably different evaluation of philosophical thought experiments. (shrink)

In their paper, ‘When are thought experiments poor ones?’ (Peijnenburg and David Atkinson, 2003, Journal of General Philosophy of Science 34, 305-322.), Jeanne Peijnenburg and David Atkinson argue that most, if not all, philosophical thought experiments are “poor” ones with “disastrous consequences” and that they share the property of being poor with some (but not all) scientific thought experiments. Noting that unlike philosophy, the sciences have the resources to avoid the disastrous consequences, Peijnenburg and Atkinson come to the conclusion that (...) the use of thought experiments in science is in general more successful than in philosophy and that instead of concocting more “recherché” thought experiments, philosophy should try to be more empirical. In this comment I will argue that Peijnenburg’s and Atkinson’s view on thought experiments is based on a misleading characterization of both, the dialectical situation in philosophy as well as the history of physics. By giving an adequate account of what the discussion in contemporary philosophy is about, we will arrive at a considerably different evaluation of philosophical thought experiments. For I am convinced that we now find ourselves at an altogether decisive turning point in philosophy, and that we are objectively justified in considering that an end has come to the fruitless conflict of systems. We are already at the present time, in my opinion, in possession of methods which make any such conflict in principle unnecessary. What is now required is their resolute application. (Schlick, ‘The Turning Point in Philosophy’, 1930/1959, p. 54). (shrink)

In this study, we sought a better understanding of how poor women made meaning of their poverty and health. Twenty research participants used varied, multiple, and at times contradictory discourses that shaped their identities as both legitimate and powerful and illegitimate and powerless. We identified four discourses in the women's talk—illegitimate dependencies, legitimate dependencies, overwhelming odds, and critique and collectivism. These four discourses revealed complexes of meanings and networks of interpretation that subverted, accommodated, and reinterpreted dominant discourses of poverty and (...) health. This examination is relevant for feminist researchers attempting to understand the impact of dominant discourses in the lives of socially marginalized women who continually struggle to establish and strengthen claims to legitimacy and moral worth. (shrink)

Over the past year, technology companies have made headlines claiming that their artificially intelligent (AI) products can outperform clinicians at diagnosing breast cancer, brain tumours, and diabetic retinopathy. Claims such as these have influenced policy makers, and AI now forms a key component of the national health strategies in England, the United States, and China. While it is positive to see healthcare systems embracing data analytics and machine learning, concerns remain about the efficacy, ethics, and safety of some commercial, AI (...) health solutions. This paper argues that improved regulation and guidance is urgently required to mitigate risks, ensure transparency and best practice, Without this, patients, clinicians, and other stakeholders cannot be assured of an app’s efficacy, and safety. (shrink)

Through personal testimony, the author details the experience of fathering a baby with a poor prenatal diagnosis. The author invites the reader to follow his journey, from learning his wife is pregnant, through their experiences as a family with their unborn daughter’s poor prenatal diagnosis, welcoming their baby girl at her birth, and ultimately finding peace in her early passing. Perinatal peer support is discussed and encouraged, drawing attention to the needs and concerns of the babies, women, and families who (...) may not know to seek help in a similar situation. Great honor is given to the beauty and sanctity of life from the perspective of a father with a sick unborn child. National Catholic Bioethics Quarterly 14.1 : 31–37. (shrink)

Evidence suggests a limited contribution to the total research output in leading obstetrics and gynaecology journals by researchers from the developing world. Editorial bias, quality of scientific research produced and language barriers have been attributed as possible causes for this phenomenon. The aim of this study was to understand the prevalence of editorial board members based out of low and lower-middle income countries in leading journals in the field of obstetrics and gynaecology. The top 21 journals in the field of (...) obstetrics and gynaecology were selected based on their impact factor, SCImago ranking and literature search. The composition of the editorial boards of these journals was studied based on World Bank Income Criteria to understand the representation status of researchers from low and lower-middle income countries. A total of 1315 board members make up the editorial composition of leading obstetrics and gynaecology journals. The majority of these editors belong to high-income countries (n = 1148; 87.3%). Low (n = 6; 0.45%) and lower-middle income (n = 55; 4.18%) countries make up for a very minuscule proportion of editorial board members. Only a meagre 9 out of 21 journals have editorial board members from these countries (42.85%). Low and low-middle countries have poor representation in the editorial boards of leading obstetrics and gynaecology journals. Poor representation in research from these countries has grave consequences for a large proportion of the global population and multidisciplinary collaborative efforts must be taken to rapidly change this statistic with immediate effect. (shrink)

What has philosophy to do with the poor? If, as has often been supposed, the poor have no time for philosophy, then why have philosophers always made time for them? Why is the history of philosophy—from Plato to Karl Marx to Jean-Paul Sartre to Pierre Bourdieu—the history of so many figures of the poor: plebes, men of iron, the demos, artisans, common people, proletarians, the masses? Why have philosophers made the shoemaker, in particular, a remarkably ubiquitous presence in this history? (...) Does philosophy itself depend on this thinking about the poor? If so, can it ever refrain from thinking for them? Jacques Rancière’s The Philosopher and His Poor meditates on these questions in close readings of major texts of Western thought in which the poor have played a leading role—sometimes as the objects of philosophical analysis, sometimes as illustrations of philosophical argument. Published in France in 1983 and made available here for the first time in English, this consummate study assesses the consequences for Marx, Sartre, and Bourdieu of Plato’s admonition that workers should do “nothing else” than their own work. It offers innovative readings of these thinkers’ struggles to elaborate a philosophy of the poor. Presenting a left critique of Bourdieu, the terms of which are largely unknown to an English-language readership, The Philosopher and His Poor remains remarkably timely twenty years after its initial publication. (shrink)

This article addresses Hannah Arendt’s controversial engagement with European imperial ventures in Africa. For many of her critics, Arendt’s description of imperialism either duplicates the ideologically inflected accounts and justifications of mass-murder, or conveys her own personal views of Africans and peoples of African descent. I argue that Arendt’s account in the “Imperialism” chapter of the Origins of Totalitarianism must be read parallel to her discussion of the conflict in Palestine between Jewish settlers and native Arabs. Rather than provide us (...) with an anthropological account of Africans, Arendt provides a political account of the necessity for cooperation in order to blunt imperial power-politics. In a second move, I develop a normative critique from Arendt’s remarks by relying on Heideggerian aspects of “World.” I argue that Arendt’s criticisms are really directed at Europeans who were unable to take the Africans’ point of view. (shrink)