Over the past three decades, philosophy of science has grown increasingly “local.” Concerns have switched from general features of scientific practice to concepts, issues, and puzzles specific to particular disciplines. Philosophy of neuroscience is a natural result. This emerging area was also spurred by remarkable recent growth in the neurosciences. Cognitive and computational neuroscience continues to encroach upon issues traditionally addressed within the humanities, including the nature of consciousness, action, knowledge, and normativity. Empirical discoveries about brain (...) structure and function suggest ways that “naturalistic” programs might develop in detail, beyond the abstract philosophical considerations in their favor. -/- The literature distinguishes “philosophy of neuroscience” and “neurophilosophy.” The former concerns foundational issues within the neurosciences. The latter concerns application of neuroscientific concepts to traditional philosophical questions. Exploring various concepts of representation employed in neuroscientific theories is an example of the former. Examining implications of neurological syndromes for the concept of a unified self is an example of the latter. In this entry, we will assume this distinction and discuss examples of both. (shrink)

This Element provides a comprehensive introduction to philosophy of neuroscience. It covers such topics as how neuroscientists procure knowledge, including not just research techniques but the use of various model organisms. It presents examples of knowledge acquired in neuroscience that are then employed to discuss more philosophical topics such as the nature of explanations developed in neuroscience, the different conception of levels employed in discussions of neuroscience, and the invocation of representations in neuroscience explanations. (...) The text emphasizes the importance of brain processes beyond those in the neocortex and then explores what makes processing in neocortex different. It consider the view that the nervous system consists of control mechanisms and considers arguments for hierarchical vs. heterarchical organization of control mechanisms. It concludes by considering implications of findings in neuroscience for how humans conceive of themselves and practices such as embracing norms. (shrink)

神經科學哲學 (philosophy of neuroscience) 是科學哲學下的一個新興子領域，主要在探討神經科學研究活動中所牽涉的哲學問題。這裡指的研究活動包含設計實驗、使用特定研究技術、工具或方法、建構模型、推理模式、與科學說明等。本條目首先將簡述神經科學哲學興 起的背景，而後詳述二十一世紀神經科學哲學的發展重點。.

How do cognitive neuroscientists explain phenomena like memory or language processing? This book examines the different kinds of experiments and manipulative research strategies involved in understanding and eventually explaining such phenomena. Against this background, it evaluates contemporary accounts of scientific explanation, specifically the mechanistic and interventionist accounts, and finds them to be crucially incomplete. Besides, mechanisms and interventions cannot actually be combined in the way usually done in the literature. This book offers solutions to both these problems based on insights (...) from experimental practice. It defends a new reading of the interventionist account, highlights the importance of non-interventionist studies for scientific inquiry, and supplies a taxonomy of experiments that makes it easy to see how the gaps in contemporary accounts of scientific explanation can be filled. The book concludes that a truly empirically adequate philosophy of science must take into account a much wider range of experimental research than has been done to date. With the taxonomy provided, this book serves a stepping-stone leading into a new era of philosophy of science—for cognitive neuroscience and beyond. (shrink)

This volume brings together new papers advancing contemporary debates in foundational, conceptual, and methodological issues in cognitive neuroscience. The different perspectives presented in each chapter have previously been discussed between the authors, as the volume builds on the experience of Neural Mechanisms Online – webinar series on the philosophy of neuroscience organized by the editors of this volume. The contributed chapters pertain to five core areas in current philosophy of neuroscience. It surveys the novel forms (...) of explanation developed in cognitive neuroscience, and looks at new concepts, methods and techniques used in the field. The book also highlights the metaphysical challenges raised by recent neuroscience and demonstrates the relation between neuroscience and mechanistic philosophy. Finally, the book dives into the issue of neural computations and representations. Assembling contributions from leading philosophers of neuroscience, this work draws upon the expertise of both established scholars and promising early career researchers. (shrink)

Philosophy and Neuroscience: A Ruthlessly Reductive Account is the first book-length treatment of philosophical issues and implications in current cellular and molecular neuroscience. John Bickle articulates a philosophical justification for investigating "lower level" neuroscientific research and describes a set of experimental details that have recently yielded the reduction of memory consolidation to the molecular mechanisms of long-term potentiation (LTP). These empirical details suggest answers to recent philosophical disputes over the nature and possibility of psycho-neural scientific reduction, including (...) the multiple realization challenge, mental causation, and relations across explanatory levels. Bickle concludes by examining recent work in cellular neuroscience pertaining to features of conscious experience, including the cellular basis of working memory, the effects of explicit selective attention on single-cell activity in visual cortex, and sensory experiences induced by cortical microstimulation. (shrink)

This article, the first of a two-part essay, presents an account of Aristotelian hylomorphic animalism that engages with recent work on neuroscience and philosophy of mind. I show that Aristotelian hylomorphic animalism is compatible with the new mechanist approach to neuroscience and psychology, but that it is incompatible with strong emergentism in the philosophy of mind. I begin with the basic claims of Aristotelian hylomorphic animalism and focus on its understanding of psychological powers embodied in the (...) nervous system. Next, I introduce the new mechanist approach to neuroscience and psychology and illustrate how it can enrich the more abstract ontological framework of Aristotelian hylomorphic animalism. In the third section of this article I establish in detail the many ways Aristotelian hylomorphic animalism is incompatible with strong emergentism in the philosophy of mind. Based on these fundamental differences I show why a criticism leveled against emergentism by the new mechanist philosophy does not hamper my proposed rapprochement between hylomorphism and the new mechanist philosophy. This conclusion, however, leaves untouched the problem I address in the second article, namely, is the new mechanist philosophy compatible with Aristotelian philosophical anthropology’s contention that intellectual operations are immaterial and interact with the psychosomatic operations of the rational animal? (shrink)

An opinionated history of neuroscience, which argues that--due to the brain's complexity--neuroscientific theories have only captured partial truths, and therefore "neurophilosophy" is unlikely to be achieved.

It is widely held that a successful theory of the mind will be neuroscientific. In this paper we ask, first, what this claim means, and, secondly, whether it is true. In answer to the first question, we argue that the claim is ambiguous between two views--one plausible but unsubstantive, and one substantive but highly controversial. In answer to the second question, we argue that neither the evidence from neuroscience itself nor from other scientific and philosophical considerations supports the controversial (...) view. (shrink)

This chapter contains sections titled: Real Reduction in Real Neuroscience Neurofunctions? Consciousness and Cellular Neuroscience Reductionist Neuroscience and “Hard Problems” Toward Genuinely Interdisciplinary Philosophy and Neuroscience.

Philosophy, in its traditional guise, addresses questions where experimental science has not yet nailed down plausible explanatory theories. Thus, the ancient Greeks pondered the nature of life, the sun, and tides, but also how we learn and make decisions. The history of science can be seen as a gradual process whereby speculative philosophy cedes intellectual space to increasingly wellgrounded experimental disciplines—first astronomy, but followed by physics, chemistry, geology, biology, archaeology, and more recently, ethology, psychology, and neuroscience. Science (...) now encompasses plausible theories in many domains, including large-scale theories about the cosmos, life, matter, and energy. The mind’s turn has now come. The classical ‘‘mind’’ questions center on free will, the self, consciousness, how thoughts can have meaning and ‘‘aboutness,’’ and how we learn and use knowledge. All these matters interlace with questions about morality: where values come from, the roles of reason and emotion in choice, and the wherefore of responsibility and punishment. The vintage mind/body problem is a legacy of Descartes: if the mind is a completely nonphysical substance, as he thought, how can it interact causally with the physical brain? Since the weight of evidence indicates that mental processes actually are processes of the brain, Descartes’ problem has disappeared. The classical mind/ body problem has been replaced with a range of questions: what brain mechanisms explain learning, decision making, self-deception, and so on. The replacement for ‘‘the mind-body problem’’ is not a single problem; it is the vast research program of cognitive neuroscience. The dominant methodology of philosophy of mind and morals in the twentieth.. (shrink)

This paper presents current trends in philosophy of mind and philosophy of neuroscience, with a special focus on neuroscientists dealing with some topics usually discussed by philosophers of mind. The aim is to detect the philosophical views of those scientists, such as Eccles, Gazzaniga, Damasio, Changeux, and others, which are not easy to classify according to the standard divisions of dualism, functionalism, emergentism, and others. As the variety of opinions in these fields is sometimes a source of (...) confusion, it is worth the effort to obtain an overall panorama of the topic. A general conclusion on epistemological and ontological issues, concerning the relationship between neurobiology and philosophy and the multi-level account of the embodied mind, is proposed. (shrink)

I propose a cautionary assessment of the recent debate concerning the impact of the dynamical approach on philosophical accounts of scientific explanation in the cognitive sciences and, particularly, the cognitive neurosciences. I criticize the dominant mechanistic philosophy of explanation, pointing out a number of its negative consequences: In particular, that it doesn’t do justice to the field’s diversity and stage of development, and that it fosters misguided interpretations of dynamical models’ contribution. In order to support these arguments, I analyze (...) a case study in computational neuroethology and show why it should not be understood through a mechanistic lens; I specially focus on Zednik’s mechanistic interpretation of the case study. In addition, I argue for a greater appreciation of the relation between explanation and other epistemic goals in the field, as well as an increased sensitivity towards the associated contextual factors. (shrink)

The biological sciences have become increasingly reliant on so-called ‘model organisms’. I argue that in this domain, the concept of a descriptive model is essential for understanding scientific practice. Using a case study, I show how such a model was formulated in a preexplanatory context for subsequent use as a prototype from which explanations ultimately may be generated both within the immediate domain of the original model and in additional, related domains. To develop this concept of a descriptive model, I (...) focus on use of the nematode worm Caenorhabditis elegans and the wiring diagrams that were developed as models of its neural structure. In addition, implications of the concept of a descriptive model, particularly its relevance for the data-phenomena distinction as well as its relation to long-standing debates on realism, are briefly examined. (shrink)

Most contemporary chemists consider quantum mechanics to be the foundational theory of their discipline, although few of the calculations that a strict reduction would seem to require have ever been produced. In this essay I discuss contemporary algebraic and diagrammatic representations of molecular systems derived from quantum mechanical models, specifically configuration interaction wavefunctions for ab initio calculations and molecular orbital energy diagrams. My aim is to suggest that recent dissatisfaction with reductive accounts of chemical theory may stem from both the (...) inability of standard accounts of reduction to incorporate the diverse forms of representation found in chemical practice and our philosophical predilection to analyze all connections between theories in terms of logical reduction. (shrink)

This new monograph _Philosophy of Neuroscience_ is a novel contribution to the relevant literatures. In this book review, I first summarise its contents, and then provide several critical points for the authors to consider. Even with these critical suggestions, the book is still highly recommended to those who work in philosophy of neuroscience, philosophy in neuroscience, neurophilosophy, philosophy of psychology, and cognitive sciences.

Some central ideas associated with developmental systems theory are outlined for non-specialists. These ideas concern the nature of biological development, the alleged distinction between “genetic” and “environmental” traits, the relations between organism and environment, and evolutionary processes. I also discuss some criticisms of the DST approach.

Biology lacks a central organism concept that unambiguously marks the distinction between organism and non-organism because the most important questions about organisms do not depend on this concept. I argue that the two main ways to discover useful biological generalizations about multicellular organization—the study of homology within multicellular lineages and of convergent evolution across lineages in which multicellularity has been independently established—do not require what would have to be a stipulative sharpening of an organism concept.

Some central ideas associated with developmental systems theory are outlined for non-specialists. These ideas concern the nature of biological development, the alleged distinction between “genetic” and “environmental” traits, the relations between organism and environment, and evolutionary processes. I also discuss some criticisms of the DST approach.

Some central ideas associated with developmental systems theory are outlined for non-specialists. These ideas concern the nature of biological development, the alleged distinction between “genetic” and “environmental” traits, the relations between organism and environment, and evolutionary processes. I also discuss some criticisms of the DST approach.

Some central ideas associated with developmental systems theory are outlined for non-specialists. These ideas concern the nature of biological development, the alleged distinction between “genetic” and “environmental” traits, the relations between organism and environment, and evolutionary processes. I also discuss some criticisms of the DST approach.

In this paper we argue that an operational organism concept can help to overcome the structural deficiency of mathematical models in biology. In our opinion, the structural deficiency of mathematical models lies mainly in our inability to identify functionally relevant biological characters in biological systems, and not so much in a lack of adequate mathematical representations of biological processes. We argue that the problem of character identification in biological systems is linked to the question of a properly formulated organism concept. (...) Lastly, we demonstrate how a decomposition of an organism into independent characters in the context of a specific biological process—such as adaptation by means of natural selection—depends on the dynamical properties and invariance conditions of the equations that describe this process. (shrink)

This paper presents two interpretations of the fiber bundle fonnalism that is applicable to all gauge field theories. The constructionist interpretation yields a substantival spacetime. The analytic interpretation yields a structural spacetime, a third option besides the familiar substantivalism and relationalism. That the same mathematical fonnalism can be derived in two different ways leading to two different ontological interpretations reveals the inadequacy of pure fonnal arguments.

The bridge between psychiatry and neuroscience is not the only one we have to build; it is also necessary to narrow the gap between neuroscience and philosophy. This does not imply reducing the latter to the former or vice versa, but rather linking each other without eliminating their own characteristics. Taking that into account, Dan Zahavi’s phenomenology of mind can make a great contribution by presenting itself like a different option within philosophy of mind, which up (...) until the last few years was dominated by the analytic tradition. In this chapter I present Zahavi’s proposal in four steps. Firstly, I clarify the term phenomenology. This question is not accidental because nowadays this concept is used by diverse traditions and with different meanings. Secondly, I make the fundamental distinction between first-person-perspective—which corresponds to Phenomenology—and third-person-perspective—compatible with neuroscience. Thirdly, I explain the methodological stages assumed by Zahavi from the Husserlian tradition. These stages enable him to study from the first-person-perspective rigorously: epoché, phenomenological reduction, eidetic variation, and intersubjective verification. Finally, I develop the issue of naturalization of Phenomenology in order to establish a dialogue between science and philosophy. For Zahavi that naturalization does not necessarily imply reductionism, but can be understood as something necessary for a fruitful exchange between those disciplines. (shrink)

The Reeh-Schlieder theorem asserts the vacuum and certain other states to be spacelike superentangled relative to local quantum fields. This motivates an inquiry into the physical status of various concepts of localization. It is argued that a covariant generalization of Newton-Wigner localization is a physically illuminating concept. When analyzed in terms of nonlocally covariant quantum fields, creating and annihilating quanta in Newton-Wigner localized states, the vacuum is seen to not possess the spacelike superentanglement that the Reeh-Schlieder theorem displays relative to (...) local fields, and to be locally empty as well as globally empty. Newton-Wigner localization is then shown to be physically interpretable in terms of a covariant generalization of the center of energy, the two localizations being identical if the system has no internal angular momentum. Finally, some of the counterintuitive features of Newton-Wigner localization are shown to have close analogues in classical special relativity. (shrink)

Caenorhabditis elegans is a tiny worm that has become the focus of a large number of worldwide research projects examining its genetics, development, neuroscience, and behavior. Recently several groups of investigators have begun to tie together the behavior of the organism and the underlying genes, neural circuits, and molecular processes implemented in those circuits. Behavior is quintessentially organismal—it is the organism as a whole that moves and mates—but the explanations are devised at the molecular and neurocircuit levels, and tested (...) in populations using protocols that span many levels of aggregation. Following a brief review of the main relevant features of C. elegans, I describe some of these circuits, and then discuss two contrasting approaches in behavioral genetics and neural network analysis of the worm. Finally, I outline the rudiments of a “field and focus” explanation model using the two contrasting approaches. (shrink)

The book "Philosophical Foundations of Neuroscience" is an engaging criticism of cognitive neuroscience from the perspective of a Wittgensteinian philosophy of ordinary language. The authors' main claim is that assertions like "the brain sees" and "the left hemisphere thinks" are integral to cognitive neuroscience but that they are meaningless because they commit the mereological fallacy—ascribing to parts of humans, properties that make sense to predicate only of whole humans. The authors claim that this fallacy is at (...) the heart of Cartesian dualism, implying that current cognitive neuroscientists are Cartesian dualists. Against this claim, we argue that the fallacy cannot be committed within Cartesian dualism either, for this doctrine does not allow for an intelligible way of asserting that a soul is part of a human being. Also, the authors' Aristotelian essentialistic outlook is at odds with their Wittgensteinian stance, and we were unconvinced by their case against explanatory reductionism. Finally, although their Wittgensteinian stance is congenial with radical behaviorism, their separation between philosophy and science seems less so because it is based on a view of philosophy as a priori. The authors' emphasis on the a priori, however, does not necessarily commit them to rationalism if it is restricted to conceptual or analytical truths. (shrink)

The study analyzes modern reductivist and antireductivist approaches to understanding the interaction between philosophy and neuroscience. It analyzes the content and grounds for using the concepts of neuroscience and neurosciences, philosophy of neuroscience, and neurophilosophy. The milestones in the development of neuroreductivism, from Patricia Churchland’s arguments in support of intertheoretic reduction through Francis Crick’s eliminativism to John Bickle’s ruthless reductionism, are described. The ontological, methodological, and epistemic grounds for the reduction to neurosciences of other ways (...) of representing mind and body are analyzed. Drawing on the post-Wittgensteinian paradigm of the philosophy of neuroscience of Max Bennett, Peter Hacker, and Andrew Reynolds, the semantic problems that arise in the neurosciences when epistemic reduction is attempted are described and derive from the inability to eliminate the basic metaphorical level of meaning-making and transmission rooted in everyday language and its figures, among which metaphors are fundamental. The descriptivist approach to the language of neurosciences is contrasted with neurorevisionism, an attempt to “correct” established ways of conceptualizing consciousness and corporeality, akin to earlier revisionisms, particularly physicalism, and forced to deal with similar problems. Reduction - the operation of the “return,” itself understood metaphorically - and antireduction, which resists scientific revisionism and “returns” understanding to the level of everyday language and philosophy to descriptive work, is presented as a circular hermeneutical movement necessary for scientific and philosophical understanding, but not leading to disciplinary hegemony or the “victory” of either side. The study concludes with a sketch of the publications included in the rubric. (shrink)

In this paper I argue that neuroscience has been harmed by the widespread adoption of seriously inadequate methodologies or philosophies of science - most notably inductivism and falsificationism. I argue that neuroscience, in seeking to understand the human brain and mind, needs to follow in the footsteps of evolution.

Writing from a scientifically and philosophically informed perspective, the authors provide a critical overview of the conceptual difficulties encountered in many current neuroscientific and psychological theories.

Drawing on the latest work in cognitive neuroscience, a philosopher proposes that delusions are narrative models that accommodate anomalous experiences.

Writing from a scientifically and philosophically informed perspective, the authors provide a critical overview of the conceptual difficulties encountered in many current neuroscientific and psychological theories.

Specifically designed to make the philosophy of mind intelligible to those not trained in philosophy, this book provides a concise overview for students and researchers in the cognitive sciences. Emphasizing the relevance of philosophical work to investigations in other cognitive sciences, this unique text examines such issues as the meaning of language, the mind-body problem, the functionalist theories of cognition, and intentionality. As he explores the philosophical issues, Bechtel draws connections between philosophical views and theoretical and experimental work (...) in such disciplines as cognitive psychology, artificial intelligence, linguistics, neuroscience, and anthropology. (shrink)

The experimental validity of research in the experimental philosophy of free will has been called into question. Several new, important studies (Murray et al. forthcoming; Nadelhoffer et al., Cognitive Science 44 (8): 1–28, 2020 ; Nadelhoffer et al., 2021; Rose et al., Cognitive Science 41 (2): 482–502, 2017 ) are interpreted as showing that the vignette-judgment model is defective because participants only exhibit a surface-level comprehension and not the deeper comprehension the model requires. Participants, it is argued, commit _bypassing_, (...) _intrusion_, and _fatalism_ errors. We respond in two ways: (1) we critique and improve existing methods for assessing deeper comprehension and (2) we develop videos to convey deterministic principles of change that succeed in significantly reducing participants’ bypassing, intrusion, and fatalism errors. Consequently, we have the best existing instrument for gauging folk intuitions about the relationship between free will and determinism. (shrink)

This chapter argues that much discussion between philosophers and neuroscientists is infected by philosophical assumptions about the nature of reduction. Instead we should pursue an unbiased examination of the methods used throughout relevant areas of neuroscience. The chapter focuses on reductionist work in the neurobiological discipline of molecular and cellular cognition. It is argued that reduction is a matter of causal intervention into low level mechanisms, and tracking of the effects of these interventions through levels. When interventions provide evidence (...) that activity in the proposed reductive mechanism co-varies reliably with activity in the target property, such that appealing to higher-level mechanisms will not add any extra explanatory power, reduction can succeed. This is explicitly contrasted with functionalisation and a posteriori approaches to reduction. (shrink)

The Oxford Handbook of Philosophy and Neuroscience is a state-of-the-art collection of interdisciplinary research spanning philosophy (of science, mind, and ethics) and current neuroscience. Containing chapters written by some of the most prominent philosophers working in this area, and in some cases co-authored with neuroscientists, this volume reflects both the breadth and depth of current work in this exciting field. Topics include the nature of explanation in neuroscience; whether and how current neuroscience is reductionistic; (...) consequences of current research on the neurobiology of learning and memory, perception and sensation, neurocomputational modeling, and neuroanatomy; the burgeoning field of neuroethics and the neurobiology of motivation that increasingly informs it; implications from neurology and clinical neuropsychology, especially in light of some bizarre symptoms involving misrepresentations of self; the extent and consequences of multiple realization in actual neuroscience; the new field of neuroeudamonia; and the neurophilosophy of subjectivity. This volume will interest philosophers working in numerous fields who wish to see how current neuroscience is being brought to bear directly on philosophical issues. It will also be of interest to neuroscientists who wish to learn how the research programs of some of their colleagues are being enriched by interaction with philosophers, and finally to those working in any interdisciplinary field who wish to see how two seemingly disparate disciplines--one traditional and humanistic, the other new and scientific--are being brought together to both disciplines' mutual benefit. (shrink)

Titles and abstracts for the Pitt-London Workshop in the Philosophy of Biology and Neuroscience: September 2001.

This book precis describes the motives behind my recent attempt to bring to bear “ruthlessly reductive” results from cellular and molecular neuroscience onto issues in the philosophy of mind. Since readers of this journal will probably be most interested in results addressing features of conscious experience, I highlight these most prominently. My main challenge is that philosophers (even scientifically-inspired ones) are missing the nature and scope of reductionism in contemporary neuroscience by focusing exclusively on higher-level cognitive (...) class='Hi'>neuroscience, and ignoring the discipline's cell-physiological and molecular-biological core. (shrink)

This chapter addresses the potential contributions of neuroscience to legal policy in general and criminal justice in particular. The central question is whether neuroscience is relevant to legal policy. The chapter begins with speculation about the source of claims for the positive influence of neuroscience. It then turns to the scientific status of behavioral neuroscience. The next section considers the two radical challenges to current policies that neuroscience allegedly poses: determinism and the death of agency. (...) The penultimate section addresses the question of the specific relevance of neuroscience to legal doctrine, practice, and institutions. The final section points to some areas warranting modest optimism. The general conclusion, however, is that neuroscience is scarcely useful at present but may become more relevant as the science progresses. (shrink)