Review of Historiography in the Twentieth Century: From Scientific Objectivity to the Postmodern Challenge by Georg G. Iggers.

There are no clear criteria regarding what kind of beliefs should count as folk-economic beliefs, or any way to make an exhaustive list that could be filtered through such criteria. This allows the target article authors, Boyer & Petersen, to cherry-pick FEBs, which results in the omission of some well-established FEBs. The authors do not sufficiently address a strong relationship between ideology and FEBs.

If social, political, and material transformation is to have a lasting impact on individuals and society, it must be integrated within ordinary experience. Refiguring the Ordinary examines the ways in which individuals' bodies, habits, environments, and abilities function as horizons that underpin their understandings of the ordinary. These features of experience, according to Gail Weiss, are never neutral, but are always affected by gender, race, social class, ethnicity, nationality, and perceptions of bodily normality. While no two people will experience the (...) ordinary in exactly the same way, the multiplicities, possibilities, overlaps, and limitations of day-to-day horizons are always intersubjectively constituted. Weiss turns her attention to changing the conditions and experiences of oppression from ordinary to extraordinary. This book is an impressive phenomenological, feminist reading of the complexities of human experience.M. V. Marder, University of Toronto, Feb. 2009. (shrink)

This guide accompanies the following article(s): ‘Full Disclosure of the “Raw Data” of Research on Humans: Citizens’ Rights, Product Manufacturer’s Obligations and the Quality of the Scientific Database.’Philosophy Compass 6/2 (2011): 90–99. doi: 10.1111/j.1747‐9991.2010.00376.x Author’s Introduction Securing consent (and informed consent) from patients and research study participants is a key concern in patient care and research on humans. Yet, the legal doctrines of consent and informed consent differ in their applications. In patient care, the judicial doctrines of consent and informed (...) consent are disclosure doctrines based on the obligation of physicians to inform their patients of the following types of information: the nature of the procedure the physician is recommending in the patent’s care (P), the alternatives to the physician‐recommendation (A), and the risks of procedure and its alternatives (R). In addition, the physician must provide truthful answers to the patient’s questions (Q) to the best of the physician’s abilities. In research on humans, the onus of disclosure by study sponsors and principal investigators is much greater than in patient care precisely because the purpose of research is not patient care. The purpose of research is the identification and development of new generalizable knowledge. Thus, participation in a research study or trial may not benefit the study volunteer at all. In addition, the participant may carry a heavy risk burden in relationship to any testing of a newly designed drug or device as part of their experiences in the research study. Presently, despite the risks borne by the research study participant, the raw data collected from volunteers in research trials are treated by courts as if they were the private property of the study sponsor rather than generally owed to the public as would be expected by an effort like research participation aimed at contributing to the development of generalizable knowledge. This paper reviews the obligations that study sponsors owe to their study participants based on the very definition of research as a systematic activity whose purpose is to develop generalizable knowledge to help all humans. Author Recommends Court cases Canterbury v. Spence, United States Court of Appeals, District of Columbia Circuit 464 F.2d 772 (1972). (Federal appellate decision heard in the District of Columbia, USA) Reibl v. Hughes, 2 S.C.R. 880 (1980). (Supreme Court of Canada) Rogers v. Whitaker, 175 C.L. R. 479 (1992). (High Court of Australia) Sidaway v. Board of Governors of the Bethlem Royal Hospital and the Maudsley Hospital and Others. 1 A.C. 871 (1985) (House of Lords) Canterbury v. Spence is the landmark Federal informed consent case in the United States heard in the District of Columbia. In this case, Judge Spottswood Robinson articulated the reasonable person standard of informed consent. This standard was subsequently adopted by the Supreme Court of Canada (Reibl v. Hughes, 2 S.C.R. 880 (1980)) and the High Court of Australia (Rogers v. Whitaker, 175 C.L. R. 479 (1992)). The House of Lords rejected the reasonable person standard in England in Sidaway v. Board of Governors of the Bethlem Royal Hospital and the Maudsley Hospital and Others. 1 A.C. 871 (1985). Book Mazur, Dennis J. The Science and Ethics of Research on Humans. Baltimore, MD: Johns Hopkins University Press, 2007. This book is a detailed guide for the review of scientific and ethical aspects of research on humans contained in the research study protocols and research informed consent forms which need to be submitted by study sponsors and principal investigators to institutional review boards (IRBs) for IRB review before a research study can receive approval to be conducted within a human study population in those institutions over which the IRB has authority. It also presents basic definitions in the area of research on humans and basic approaches to help conduct a deep review of the underlying scientific and ethical issues that are present within a research study protocol and its accompanying research informed consent form. Report National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. The Belmont Report: Ethical Guidelines for the Protection of Human Subjects of Research. Washington, DC: DHEW Publications, 1978 (78‐0012). This U.S. National Commission in the Belmont Report argued for the necessity of a reasonable volunteer standard in research on humans in the United States. Arguing that the professional standard and the reasonable person standard of consent and informed consent were insufficient to base a disclosure standard in research on humans, this National Commission developed the reasonable volunteer standard where a study participant is to be approached in research informed consent with that information that a reasonable volunteer would want to know. Online Materials Belmont Report: Syllabus Topics for Lecture and Discussion Week I: Introduction and Overview Readings: Rogers v. Whitaker, 175 C.L.R. 479 (1992). (High Court of Australia) Sidaway v. Board of Governors of the Bethlem Royal Hospital and the Maudsley Hospital and Others. 1 A.C. 871 (1985) (House of Lords) Week II: The Different Standards of Consent and Informed Consent Readings: Canterbury v. Spence, 464 F.2d 772 (1972). (Federal appellate opinion heard in the District of Columbia) Sidaway v. Board of Governors of the Bethlem Royal Hospital and the Maudsley Hospital and Others. 1 A.C. 871 (1985) (House of Lords) Week III: Definition of Research Reading: Mazur, Dennis J. The Science and Ethics of Research on Humans. Baltimore, MD: Johns Hopkins University Press, 2007. (Especially Chapters 2 and 3) Week IV: How to Review a Research Study Protocol and Research Informed Consent Form Reading: Mazur, Dennis J. The Science and Ethics of Research on Humans. Baltimore, MD: Johns Hopkins University Press, 2007. (Especially Chapters 4–6, 10, and 12–14) Week V: Obligations in Research of Humans Versus Patient Care Reading: National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. The Belmont Report: Ethical Guidelines for the Protection of Human Subjects of Research. Washington, DC: DHEW Publications, 1978 (78‐0012). Focus Questions • How do the judicial doctrines of consent in England and Australia compare to the judicial doctrines of informed consent in the United States and Canada? • How does a professional standard of disclosure differ from a reasonable person standard of disclosure? • What is the definition of research? • How is a research study (study proposal and research informed consent form) reviewed from scientific and ethical bases for considerations of approval by an IRB? • How do the obligations of a study sponsor, a principal investigator, and a research team conducting a research trial on human study participants differ from the obligations of a physician caring for a patient? • Should all raw data of research derived from humans be made available to the public for use in developing generalizable knowledge to help others, or should raw data be considered the private property of the study sponsors (for example, prescription drug manufacturers), who fund the research trials? Seminar/project Idea Draw a timeline of the development of the basic concepts of consent and informed consent in patient care and in patient research. On this timeline, first place the dates of the key court cases in England, the United States, Canada, and Australia on consent and informed consent. Then place the date of the development of the Belmont Report. Why do differences exist between these four countries in terms of the legal requirements of informedness of a patient (in medical care) and a study participant (in medical research)? What roles if any do the concepts of self‐determination and self‐decision have in consent and informed consent in patient care and in informed consent in research on humans among the four countries of interest? What are the realities of research on human participants that require a new standard of informed consent, the reasonable volunteer standard, to be developed beyond the two standards in patient care, the professional standard, and the reasonable person standard? Counterpoint Arguments The following are counterpoint arguments that need to be appreciated to more fully understand the concepts that impact the thesis that ‘raw data’ should be open to the public to allow the opportunity of checking of the results of its associated scientific paper and for further analysis. De‐Identified (Anonymized) Raw Data A current approach to identifying (anonymizinig) raw data is based on the Health Insurance Portability and Accountability Act (HIPAA) of 1996 (P.L.104‐191). HIPAA was enacted by the U.S. Congress in 1996 to keep a person’s medical information private. In a research study, a person’s private medical information can become research data. HIPAA’s Privacy Rule allows a covered entity to de‐identify data by removing all 18 elements that could be used to identify the individual or the individual’s relatives, employers, or household members; these elements are enumerated in the Privacy Rule. The covered entity must also have no actual knowledge that the remaining information could be used alone or in combination with other information to identify the individual who is the subject of the information. Under this method, the identifiers that must be removed are the following: 1 Names. 2 All geographic subdivisions smaller than a state, including street address, city, county, precinct, ZIP Code, and their equivalent geographical codes, except for the initial three digits of a ZIP Code if, according to the current publicly available data from the Bureau of the Census: 2a. The geographic unit formed by combining all ZIP Codes with the same three initial digits contains more than 20,000 people. 2b. The initial three digits of a ZIP Code for all such geographic units containing 20,000 or fewer people are changed to 000. 3 All elements of dates (except year) for dates directly related to an individual, including birth date, admission date, discharge date, and date of death, and all ages over 89 and all elements of dates (including year) indicative of such age, except that such ages and elements may be aggregated into a single category of age 90 or older. 4 Telephone numbers. 5 Facsimile numbers. 6 Electronic mail addresses. 7 Social security numbers. 8 Medical record numbers. 9 Health plan beneficiary numbers. 10 Account numbers. 11 Certificate/license numbers. 12 Vehicle identifiers and serial numbers, including license plate numbers. 13 Device identifiers and serial numbers. 14 Web universal resource locators (URLs). 15 Internet protocol (IP) address numbers. 16 Biometric identifiers, including fingerprints and voiceprints. 17 Full‐face photographic images and any comparable images. 18 Any other unique identifying number, characteristic, or code, unless otherwise permitted by the Privacy Rule for re‐identification. Even though ‘raw data’ can be de‐identified (anonymized) so that there is no way to trace back the data to the study participant from which it was drawn, there are still questions whether the ‘de‐identified raw data’ can be given to other researchers or made public without the original study participant’s approval. It may be the case that this approval could be done at the start of any research study where the individual considering study participation would be counseled on what the process of de‐identification consists of and would be asked whether the participant would allow use of the data by other researchers or made available to the public in a de‐identified state. However, there may be questions of the study participants as to whether the data are truly de‐identified and untraceable back to the study participant since the participant would not be able to see the process actually being carried out in detail in all relevant circumstances. Using Raw Data in Context Simply being in possession of raw data is never enough to build on that data from a research perspective. Researchers need to understand the context of the scientific research study in which the data were collected. This research context includes (but is not limited to): (i) the scientific hypothesis of the research study, (ii) the inclusion and exclusion criteria selected by the research designers of the study to determine which study participants were included and which were excluded from the study, (iii) the methods used to collect the data and possibilities of errors in the data collection processes, and (iv) answers to questions regarding whether any data were excluded from the study data and why these data were excluded. Ownership Rights Over Data There are ownership rights over data. Ownership rights include court decision making related to the question which parties are to be considered as the owners of the data. Possible owners here include (but are not limited to) (i) the study sponsor whose only role was to fund that study, (ii) the principal investigator(s) who developed the scientific hypothesis, and (iii) individual study participants through special contracts made by individual participants who negotiate such contracts with study sponsors and principal investigators to share in the ownership of data. Examples of such data are participant sources of unique gene lines or unique cell lines to be used in future research. Objections to Data Sharing Finally, individual researchers may simply object to sharing data. A researcher’s arguments here may be simply stating that he or she has a right to fully analyze the data since the collection of the data was the researchers’ idea in the first place. These researchers may argue that they have the right to mine the data as fully as they can before deciding to make the data open to the public for others to analyze. Works Cited 1 Kaiser, J. ‘Making Clinical Data Widely Available.’Science 322.5899 (10 Oct. 2008): 217–8. 2 de Lusignan, S., J.F. Metsemakers, P. Houwink, V. Gunnarsdottir, and J. van der Lei. ‘Routinely Collected General Practice Data: Goldmines for Research? A Report of the European Federation for Medical Informatics Primary Care Informatics Working Group (EFMI PCIWG) from MIE2006, Maastricht, The Netherlands.’Informatics in Primary Care 14.3 (2006): 203–9. 3 Sim, I. ‘Human Studies Database Project’, CTSA Data Repositories Symposium (17 Oct. 2008). 23 Nov. 2010. 4 Sim, I., C.G. Chute, H. Lehmann, R. Nagarajan, M. Nahm, and R.H. Scheuermann. ‘Keeping Raw Data in Context.’Science 323.5915 (6 Feb. 2009): 713. 5 U.S. Department of Health and Human Services, National Institutes of Health, HIPAA Privacy Rule, Information for Researchers. 13 Nov. 2010. 6 Wilczynski, N.L., R.B. Haynes, and Hedges Team. ‘EMBASE Search Strategies for Identifying Methodologically Sound Diagnostic Studies for Use by Clinicians and Researchers.’BMC Medicine 29.3 (March 2005): 7. (shrink)

This guide accompanies the following article(s): ‘Full Disclosure of the “Raw Data” of Research on Humans: Citizens’ Rights, Product Manufacturer’s Obligations and the Quality of the Scientific Database.’Philosophy Compass 6/2 (2011): 90–99. doi: 10.1111/j.1747‐9991.2010.00376.x Author’s Introduction Securing consent (and informed consent) from patients and research study participants is a key concern in patient care and research on humans. Yet, the legal doctrines of consent and informed consent differ in their applications. In patient care, the judicial doctrines of consent and informed (...) consent are disclosure doctrines based on the obligation of physicians to inform their patients of the following types of information: the nature of the procedure the physician is recommending in the patent’s care (P), the alternatives to the physician‐recommendation (A), and the risks of procedure and its alternatives (R). In addition, the physician must provide truthful answers to the patient’s questions (Q) to the best of the physician’s abilities. In research on humans, the onus of disclosure by study sponsors and principal investigators is much greater than in patient care precisely because the purpose of research is not patient care. The purpose of research is the identification and development of new generalizable knowledge. Thus, participation in a research study or trial may not benefit the study volunteer at all. In addition, the participant may carry a heavy risk burden in relationship to any testing of a newly designed drug or device as part of their experiences in the research study. Presently, despite the risks borne by the research study participant, the raw data collected from volunteers in research trials are treated by courts as if they were the private property of the study sponsor rather than generally owed to the public as would be expected by an effort like research participation aimed at contributing to the development of generalizable knowledge. This paper reviews the obligations that study sponsors owe to their study participants based on the very definition of research as a systematic activity whose purpose is to develop generalizable knowledge to help all humans. Author Recommends Court cases Canterbury v. Spence, United States Court of Appeals, District of Columbia Circuit 464 F.2d 772 (1972). (Federal appellate decision heard in the District of Columbia, USA) Reibl v. Hughes, 2 S.C.R. 880 (1980). (Supreme Court of Canada) Rogers v. Whitaker, 175 C.L. R. 479 (1992). (High Court of Australia) Sidaway v. Board of Governors of the Bethlem Royal Hospital and the Maudsley Hospital and Others. 1 A.C. 871 (1985) (House of Lords) Canterbury v. Spence is the landmark Federal informed consent case in the United States heard in the District of Columbia. In this case, Judge Spottswood Robinson articulated the reasonable person standard of informed consent. This standard was subsequently adopted by the Supreme Court of Canada (Reibl v. Hughes, 2 S.C.R. 880 (1980)) and the High Court of Australia (Rogers v. Whitaker, 175 C.L. R. 479 (1992)). The House of Lords rejected the reasonable person standard in England in Sidaway v. Board of Governors of the Bethlem Royal Hospital and the Maudsley Hospital and Others. 1 A.C. 871 (1985). Book Mazur, Dennis J. The Science and Ethics of Research on Humans. Baltimore, MD: Johns Hopkins University Press, 2007. This book is a detailed guide for the review of scientific and ethical aspects of research on humans contained in the research study protocols and research informed consent forms which need to be submitted by study sponsors and principal investigators to institutional review boards (IRBs) for IRB review before a research study can receive approval to be conducted within a human study population in those institutions over which the IRB has authority. It also presents basic definitions in the area of research on humans and basic approaches to help conduct a deep review of the underlying scientific and ethical issues that are present within a research study protocol and its accompanying research informed consent form. Report National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. The Belmont Report: Ethical Guidelines for the Protection of Human Subjects of Research. Washington, DC: DHEW Publications, 1978 (78‐0012). This U.S. National Commission in the Belmont Report argued for the necessity of a reasonable volunteer standard in research on humans in the United States. Arguing that the professional standard and the reasonable person standard of consent and informed consent were insufficient to base a disclosure standard in research on humans, this National Commission developed the reasonable volunteer standard where a study participant is to be approached in research informed consent with that information that a reasonable volunteer would want to know. Online Materials Belmont Report: Syllabus Topics for Lecture and Discussion Week I: Introduction and Overview Readings: Rogers v. Whitaker, 175 C.L.R. 479 (1992). (High Court of Australia) Sidaway v. Board of Governors of the Bethlem Royal Hospital and the Maudsley Hospital and Others. 1 A.C. 871 (1985) (House of Lords) Week II: The Different Standards of Consent and Informed Consent Readings: Canterbury v. Spence, 464 F.2d 772 (1972). (Federal appellate opinion heard in the District of Columbia) Sidaway v. Board of Governors of the Bethlem Royal Hospital and the Maudsley Hospital and Others. 1 A.C. 871 (1985) (House of Lords) Week III: Definition of Research Reading: Mazur, Dennis J. The Science and Ethics of Research on Humans. Baltimore, MD: Johns Hopkins University Press, 2007. (Especially Chapters 2 and 3) Week IV: How to Review a Research Study Protocol and Research Informed Consent Form Reading: Mazur, Dennis J. The Science and Ethics of Research on Humans. Baltimore, MD: Johns Hopkins University Press, 2007. (Especially Chapters 4–6, 10, and 12–14) Week V: Obligations in Research of Humans Versus Patient Care Reading: National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. The Belmont Report: Ethical Guidelines for the Protection of Human Subjects of Research. Washington, DC: DHEW Publications, 1978 (78‐0012). Focus Questions • How do the judicial doctrines of consent in England and Australia compare to the judicial doctrines of informed consent in the United States and Canada? • How does a professional standard of disclosure differ from a reasonable person standard of disclosure? • What is the definition of research? • How is a research study (study proposal and research informed consent form) reviewed from scientific and ethical bases for considerations of approval by an IRB? • How do the obligations of a study sponsor, a principal investigator, and a research team conducting a research trial on human study participants differ from the obligations of a physician caring for a patient? • Should all raw data of research derived from humans be made available to the public for use in developing generalizable knowledge to help others, or should raw data be considered the private property of the study sponsors (for example, prescription drug manufacturers), who fund the research trials? Seminar/project Idea Draw a timeline of the development of the basic concepts of consent and informed consent in patient care and in patient research. On this timeline, first place the dates of the key court cases in England, the United States, Canada, and Australia on consent and informed consent. Then place the date of the development of the Belmont Report. Why do differences exist between these four countries in terms of the legal requirements of informedness of a patient (in medical care) and a study participant (in medical research)? What roles if any do the concepts of self‐determination and self‐decision have in consent and informed consent in patient care and in informed consent in research on humans among the four countries of interest? What are the realities of research on human participants that require a new standard of informed consent, the reasonable volunteer standard, to be developed beyond the two standards in patient care, the professional standard, and the reasonable person standard? Counterpoint Arguments The following are counterpoint arguments that need to be appreciated to more fully understand the concepts that impact the thesis that ‘raw data’ should be open to the public to allow the opportunity of checking of the results of its associated scientific paper and for further analysis. De‐Identified (Anonymized) Raw Data A current approach to identifying (anonymizinig) raw data is based on the Health Insurance Portability and Accountability Act (HIPAA) of 1996 (P.L.104‐191). HIPAA was enacted by the U.S. Congress in 1996 to keep a person’s medical information private. In a research study, a person’s private medical information can become research data. HIPAA’s Privacy Rule allows a covered entity to de‐identify data by removing all 18 elements that could be used to identify the individual or the individual’s relatives, employers, or household members; these elements are enumerated in the Privacy Rule. The covered entity must also have no actual knowledge that the remaining information could be used alone or in combination with other information to identify the individual who is the subject of the information. Under this method, the identifiers that must be removed are the following: 1 Names. 2 All geographic subdivisions smaller than a state, including street address, city, county, precinct, ZIP Code, and their equivalent geographical codes, except for the initial three digits of a ZIP Code if, according to the current publicly available data from the Bureau of the Census: 2a. The geographic unit formed by combining all ZIP Codes with the same three initial digits contains more than 20,000 people. 2b. The initial three digits of a ZIP Code for all such geographic units containing 20,000 or fewer people are changed to 000. 3 All elements of dates (except year) for dates directly related to an individual, including birth date, admission date, discharge date, and date of death, and all ages over 89 and all elements of dates (including year) indicative of such age, except that such ages and elements may be aggregated into a single category of age 90 or older. 4 Telephone numbers. 5 Facsimile numbers. 6 Electronic mail addresses. 7 Social security numbers. 8 Medical record numbers. 9 Health plan beneficiary numbers. 10 Account numbers. 11 Certificate/license numbers. 12 Vehicle identifiers and serial numbers, including license plate numbers. 13 Device identifiers and serial numbers. 14 Web universal resource locators (URLs). 15 Internet protocol (IP) address numbers. 16 Biometric identifiers, including fingerprints and voiceprints. 17 Full‐face photographic images and any comparable images. 18 Any other unique identifying number, characteristic, or code, unless otherwise permitted by the Privacy Rule for re‐identification. Even though ‘raw data’ can be de‐identified (anonymized) so that there is no way to trace back the data to the study participant from which it was drawn, there are still questions whether the ‘de‐identified raw data’ can be given to other researchers or made public without the original study participant’s approval. It may be the case that this approval could be done at the start of any research study where the individual considering study participation would be counseled on what the process of de‐identification consists of and would be asked whether the participant would allow use of the data by other researchers or made available to the public in a de‐identified state. However, there may be questions of the study participants as to whether the data are truly de‐identified and untraceable back to the study participant since the participant would not be able to see the process actually being carried out in detail in all relevant circumstances. Using Raw Data in Context Simply being in possession of raw data is never enough to build on that data from a research perspective. Researchers need to understand the context of the scientific research study in which the data were collected. This research context includes (but is not limited to): (i) the scientific hypothesis of the research study, (ii) the inclusion and exclusion criteria selected by the research designers of the study to determine which study participants were included and which were excluded from the study, (iii) the methods used to collect the data and possibilities of errors in the data collection processes, and (iv) answers to questions regarding whether any data were excluded from the study data and why these data were excluded. Ownership Rights Over Data There are ownership rights over data. Ownership rights include court decision making related to the question which parties are to be considered as the owners of the data. Possible owners here include (but are not limited to) (i) the study sponsor whose only role was to fund that study, (ii) the principal investigator(s) who developed the scientific hypothesis, and (iii) individual study participants through special contracts made by individual participants who negotiate such contracts with study sponsors and principal investigators to share in the ownership of data. Examples of such data are participant sources of unique gene lines or unique cell lines to be used in future research. Objections to Data Sharing Finally, individual researchers may simply object to sharing data. A researcher’s arguments here may be simply stating that he or she has a right to fully analyze the data since the collection of the data was the researchers’ idea in the first place. These researchers may argue that they have the right to mine the data as fully as they can before deciding to make the data open to the public for others to analyze. Works Cited 1 Kaiser, J. ‘Making Clinical Data Widely Available.’Science 322.5899 (10 Oct. 2008): 217–8. 2 de Lusignan, S., J.F. Metsemakers, P. Houwink, V. Gunnarsdottir, and J. van der Lei. ‘Routinely Collected General Practice Data: Goldmines for Research? A Report of the European Federation for Medical Informatics Primary Care Informatics Working Group (EFMI PCIWG) from MIE2006, Maastricht, The Netherlands.’Informatics in Primary Care 14.3 (2006): 203–9. 3 Sim, I. ‘Human Studies Database Project’, CTSA Data Repositories Symposium (17 Oct. 2008). 23 Nov. 2010. 4 Sim, I., C.G. Chute, H. Lehmann, R. Nagarajan, M. Nahm, and R.H. Scheuermann. ‘Keeping Raw Data in Context.’Science 323.5915 (6 Feb. 2009): 713. 5 U.S. Department of Health and Human Services, National Institutes of Health, HIPAA Privacy Rule, Information for Researchers. 13 Nov. 2010. 6 Wilczynski, N.L., R.B. Haynes, and Hedges Team. ‘EMBASE Search Strategies for Identifying Methodologically Sound Diagnostic Studies for Use by Clinicians and Researchers.’BMC Medicine 29.3 (March 2005): 7. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:_Russell_ journal (home office): E:CPBRRUSSJOURTYPE2602\REVIEWS.262 : 2007-01-24 01:12 Reviews 185 A NORWEGIAN ANTHOLOGY OF RUSSELL ON WAR, PEACE AND PACIFISM Stefan Andersson Theology and Religious Studies / U. of Lund s223 62 Lund, Sweden [email protected] Øystein Hide, ed. Bertrand Russell om krig, fred og pasifisme [Bertrand Russell on war, peace and pacifism]. Oslo: Humanist Forlag, 2006. Pp. 261. isbn 8292622101. 268 Kroner. Paperbound. his is a selected anthology of (...) Russell’s writings and interviews on war, Tpeace and pacifism edited by the Norwegian Øystein Hide, who was born in 1975 and has the equivalent of a ma in philosophy from a Norwegian university. He did graduate work at the University of Southampton in 2001–04. He has worked at the Wittgenstein Archives in Bergen and at the University of Bergen. He has done research at the Bertrand Russell Archives1 and is a member of the Mind Association. He has translated Wittgenstein’s Zettel and Über Gewissheit into Norwegian and has done other philosophically relevant work in both Norwegian and English. Øystein Hide has supplied his anthology with an introduction that contains a number of minor factual mistakes that are a bit disturbing, but they do not overshadow his main message that Russell’s writings on war, peace and pacifism are still worth reading. He starts out by distinguishing between “the two Bertrand Russells”: the philosopher and what he calls “the political humanist”. Although Hide does not spend much energy on explaining exactly what he means by it, I find this a thought-provoking expression that to me suggests a secular humanist who is prepared to act on his convictions. He compares Russell to the Norwegian philosopher Arne Næss, who also was a political activist and acted according to his deepest beliefs. Hide says about Russell: “For many people Russell has become the great philosopher who also actively contributed to the general political debate and who, in the capacity of being a philosopher, gave the lovers of peace a philosophical and intellectual alibi with which they could decorate their struggles” (p. 11). 1 Notably resulting in his article, “Wittgenstein’s Books at the Bertrand Russell Archives and the Influence of Scientific Literature on Wittgenstein’s Early Philosophy”, Philosophical Investigations, 27 (Jan. 2004): 68–91. _Russell_ journal (home office): E:CPBRRUSSJOURTYPE2602\REVIEWS.262 : 2007-01-24 01:12 186 Reviews Russell’s position as a philosopher and political activist in Norway is more or less the same as in the other Nordic countries, and although Hide’s book is Norwegian a lot of Swedes, Danes, Finns and Icelanders will be able to benefit from the collection. There is no mention, however, of Russell’s only trip to Norway (in 1948), which had a political purpose. Hide has divided his collection into two parts. The first part contains ten texts written between 1916 and 1920, and the second part contains five between 1950 and 1960. He does not say a lot about why he has included these texts and excluded others. These are the selections he offers: Part 1: “War as an Institution”, Chapter 3 from Principles of Social Reconstruction (1916) “Why the War Continues”, The UDC, 2 (10 Feb. 1917); in Papers 14 “National Service”, The Tribunal, 47 (15 Feb. 1917); Papers 14 “War and Individual Liberty”, The Tribunal, 50 (8 March 1917); Papers 14 “Pacifism and Revolution”, The Tribunal, 67 (19 July 1917); Papers 14 “The International Outlook”, The Pioneer, 347 (10 Nov. 1917); Papers 14 “Draft of Defence” (for Russell’s 1918 trial); Papers 14 “Government and Law”, Chapter 5 from Roads to Freedom (1918) “The World as It Could be Made”, Chapter 8 from Roads to Freedom (1918) “Bolshevik Criticism of Democracy”, Chapter 3 of Part 2 of The Practice and Theory of Bolshevism (1920) Part 2: “Politically Important Desires”, Chapter 2 of Part 2 of Human Society in Ethics and Politics (1954); Nobel Prize speech, 1950 How Near Is War? (London: Fleet Street Forum, 1952); interview “Man’s Peril”, The Listener, 52 (30 Dec. 1954); Papers 28 “The Road to Peace”, The Bomb: Challenge and Answer (London: Batsford, 1955); Papers 28 “War and Pacifism”, Bertrand Russell Speaks His Mind (1960... (shrink)

On September 27, 2016 people across the world looked down at their buzzing phones to see the AP Alert: “Baby born with DNA from 3 people, first from new technique.” It was an announcement met with confusion by many, but one that polarized the scientific community almost instantly. Some celebrated the birth as an advancement that could help women with a family history of mitochondrial diseases prevent the transmission of the disease to future generations; others held it unethical, citing medical (...) tourism and consequences for the future of the therapy. The child in question was actually born a few months earlier on April 6, 2016, but the research was published a few months later in the October edition of Fertility and Sterility. The mother carries DNA that could have given the baby Leigh Syndrome, a severe neurological disorder characterized by psychomotor regression that typically results in death between ages two and three.[1] Also known as subacute necrotizing encephalomyelopathy, Leigh Syndrome is caused by genetic mutations in mitochondrial DNA, which causes defective oxidative phosphorylation. Because people with this condition cannot re-form ATP, “demyleniation, gliosis, necrosis, spongiosis, or capillary proliferation”[2] can occur, thereby producing bilateral lesions across the central nervous system. The 36-year-old mother previously had four miscarriages and successfully birthed two children, both of whom survived less than six years due to the syndrome. For religious reasons, the mother opted for Spindle Nuclear Transfer instead of Pronuclear Transfer,[3] which many religious organizations oppose because it entails the destruction of fertilized eggs.[4] In Pronuclear Transfer, both the parent and donor egg are fertilized. The parent’s nuclear material is then removed from the egg containing mutated mitochondria and inserted into the fertilized donor egg—from which the original nuclear material has been removed and destroyed. Spindle Nuclear Transfer, on the other hand, removes the mother’s nuclear material from the egg with unhealthy mitochondria, then implants it into a donor’s egg. The newly created egg is then fertilized with the father’s sperm. This Spindle Nuclear Transfer was performed in Mexico by a team of doctors led by Dr. John Zhang, the founder of the New Hope Fertility Center in New York City. In their report, the doctors outline that five oocytes were successfully reconstituted, four of which developed into blastocysts. Only one was euploid: containing 46 XY chromosomes. Researchers then biopsied that blastocyst and found that the transmission rate of maternal mtDNA was, “5.10 ± 1.11% and the heteroplasmy level for 8993T>G was 5.73%.”[5] This indicates that at the blastocyst stage, around five percent of the mitochondria are from the original maternal egg with the mutation for Leigh Syndrome. After birth, they biopsied different tissues and found that they had an average of less than 1.60 ± 0.92% of transmitted mtDNA from the original maternal egg. The baby is reportedly doing well and the team of doctors concluded that “[h]uman oocytes reconstituted by SNT are capable of producing a healthy live birth. SNT may provide a novel treatment option in minimizing pathogenic mtDNA transmission from mothers to their babies."[6] Even when considered theoretically, Spindle Nuclear Transfer is controversial. Many doctors believe that the risks at this stage of research are too great. Dr. Trevor Stammers, a bioethicist at St. Mary’s University in London, points out: “We do not yet have a clear picture of the interaction between nuclear DNA and mitochondria.”[7] Others hold that faulty mitochondrial DNA can still be transferred during the procedure. Still more argue this technology could create problems because of germline modification.[8] Dr. Paul Knoepfler, a cell biologist at the UC Davis School of Medicine, explains: “Since this is uncharted territory and the children born from this technology would have heritable genetic changes, there are also significant unknown risks to future generations.”[9] However, proponents counter these arguments. They say the benefits outweigh the risks, as “mitochondrial replacement techniques [like Spindle Nuclear Transfer] would eliminate maternal transmission of mitochondrial disease… allowing a woman with a family history of mitochondrial diseases to ensure her children would not be affected.”[10] Additionally, experts say that no symptoms will occur if less than 20% of the transferred mitochondrial DNA is faulty.[11] And while opponents see potential germline modification as a problem, advocates answer that this could stop a family history of mitochondrial disease, which they deem a more serious concern. In this case specifically, however, there are more issues at hand. While the team of doctors did eliminate the possibility of germline modification by selecting a male embryo, there are other ethical concerns. Some argue that this case could be described as “medical tourism.” While New Hope Medical Clinic does maintain a branch in Mexico, Dr. Zhang stated that Mexico has “no rules.”[12] It is a country with underdeveloped regulations, making it difficult to confirm that doctors adhere to widely-held medical and ethical standards. Furthermore, while it is highly unlikely that the child will develop Leigh’s Syndrome, Dr. Dietrich Egli of the New York Stem Cell Foundation says the 5% mitochondrial transfer rate indicates that the technique “was not carried out well.”[13] He points to studies of embryos where the rate of mtDNA transfer was almost ten times lower. Spindle Nuclear Transfer is currently legal in the UK,[14] and many are hoping to see it legalized in the US, although Congress currently prohibits the FDA from considering applications that would entail trials in people.[15] While Dr. Zhang’s work is arguably revolutionary, many wonder if the manner in which this study was performed—in Mexico and with a high mitochondrial transfer rate—will impact the technology’s future in the US. Last week, Dr. Zhang presented the report to scientists gathered in Salt Lake City, saying that while science isn’t a race, it is “in a sense, a race for the family to find a cure, to find hope.”[16] Only time will tell if this study set back other families racing and hoping for a cure. References 1. "Leigh Syndrome." Genetics Home Reference, US National Library of Medicine, 25 Oct. 2016. Accessed 26 Oct. 2016. 2. McKusick, Victor A., and Ada Hamosh. "LEIGH SYNDROME; LS." Online Mendelian Inheritance in Man, Johns Hopkins University, 20 Jan. 2016. Accessed 30 Oct. 2016. 3. Zhang, J, H Liu, S Luo, A Chavez-Badiola, and Z Liu. "First live birth using human oocytes reconstituted by spindle nuclear transfer for mitochondrial DNA mutation causing Leigh syndrome." Fertility and Sterility, vol. 106, no. 3, 2016, pp. e375-76. Accessed 30 Oct. 2016. 4. Sample, Ian. "‘Three-parent’ babies explained: what are the concerns and are they justified?" The Guardian, 2 Feb. 2015. Accessed 30 Oct. 2016. 5. Zhang, et al. 6. Ibid. 7. Knapton, Sarah. "Three-parent babies: the arguments for and against." The Telegraph, 3 Feb. 2015. 8. Ibid. 9. Ibid. 10. "Mitochondrial Replacement Therapy FAQs." New York Stem Cell Foundation Research Institute, New York Stem Cell Foundation. Accessed 30 Oct. 2016. 11. Reardon, Sara. "‘Three-parent baby’ claim raises hopes — and ethical concerns." Nature, 28 Sept. 2016. Accessed 30 Oct. 2016. 12. Hamzelou, Jessica. "Exclusive: World’s first baby born with new “3 parent” technique." New Scientist, 27 Sept. 2016. Accessed 30 Oct. 2016. 13. Reardon, Sara. "‘Three-parent baby’ claim raises hopes — and ethical concerns." Nature, 28 Sept. 2016. Accessed 30 Oct. 2016. 14. "3-Person IVF: A Resource Page." Center for Genetics and Society, 24 Oct. 2016. Accessed 30 Oct. 2016. 15. Ritter, Malcolm. "Baby born with DNA from 3 people, first from new technique." Associated Press, 27 Sept. 2016. Accessed 30 Oct. 2016. 16. Chen, Daphne. "Controversy swirls around first three-parent baby." Deseret News, 19 Oct. 2016. Accessed 30 Oct. 2016. Works consulted Swetlitz, Ike. "FDA urged to approve ‘three-parent embryos,’ a new frontier in reproduction." STAT, 3 Feb. 2016. Accessed 30 Oct. 2016. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:James's Faith-Ladder JAMES C. S. WERNHAM JAMES WROTE OFTEN of a "faith-ladder."' What he said about it has drawn some side-glances from critics, but not yet any sustained and careful look.' That is surprising, for what he says is puzzling enough to invite inquiry. It is also important enough to deserve it. His presentations of the ladder show significant variation, so it is useful to look at a generous (...) sample. In the interest of brevity the following six passages have been extracted from contexts which sometimes have an important bearing on them. The unquoted contexts will get attention as needed. 1. "The inner process is a succession of 'synthetic judgments'. What is so good, may be, ought to be, must be, shall be,--so far as I am concerned, I won't admit the opposite. ''s 2. "[W]e have a conception which being opposed by another is only probab /e. But we feel, it is so good that it isfit to be true, it ought to be true, it must be true etc. And then we say it shall be true for me, it/s true. ''4 3- "Its [faith's] natural logic is the Sorites: fit to be, ought to be, may be, must be, shall be, is etc.''5 4. "The following steps may be called the 'faith-ladder': ~. There is nothing absurd in a certain view of the world being true, nothing self-contradictory; ' To the best of my knowledge, the name "faith-ladder'"does not occur before 19o6. It occurs in "Faith and Reason" and in "Faith and the Right to Believe," both written in that year. But expositions of the thing predate the name. They are found as early as 1899, and in close connection with the will-to-believe doctrine. 9 Levinson's discussion is a partial exception. His treatment is more extended than most. See H. S. Levinson, $c/ence, Metaphysicsand the Chan~e of Salvation (Missoula, MT: Scholars Press, 1978), 161--67; also his The Religious Investigations of Wdliam James (Chapel Hill: University of North Carolina Press, 198 0, 231-34. s Letter to Baldwin, quoted in'R. B. Perry, The Thoughtand Characterof WilliamJames, 2 vols. (Boston: Little, Brown and Co., 1935), 2: 243. 4 Letter to Marshall, Feb. 9, 1899, quoted in Perry, Thought and Character,2: 24~. 5 William James, A Pluralistic Universe (Cambridge, MA and London: Harvard Universit~t Press, 1977), 199. [1o5] lO6 JOURNAL OF THE HISTORY OF PHILOSOPHY 28" 1 JANUARY I990 2. If might have been true under certain conditions; 3- It may be true even now; 4. It isfit to be true; 5- It ought to be true; 6. It must be true; 7- It s/m//be true, at any rate true for me. ''6 5. "Faith's form of argument is something like this: Considering a view of the world: 'It isfit to be true', she feels; 'it would be well if it were true; it might be true; it may be true; it ought to be true', she says; 'it must be true', she continues; 'it shall be true', she concludes, 'for me; that is, I will treat it as if it were true so far as my advocacy and actions are concerned'. ''7 6. "A conception of the world arises in you somehow, no matter how. Is it true or not? you ask. It might be true somewhere, you say, for it is not self-contradictory. It may be true, you continue, even here and now. It is fit to be true, it would be well if it were true, it ought to be true, you presently feel. It must be true, something persuasive in you whispers next; and then--as a final result--it shall be held for true, you decide; it shall be as if true, for you. ''s 9. Between these statements there are clear similarities and clear differences too. Some of them deserve to be noted, some to be noted and explored. a. In these accounts of it the ladder varies in the number of its rungs. By James's own count in one place, it has as many as seven. In... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:RECENT ACQUISITIONS Sheila Turcon Ready Division / McMaster U. Library Russell Research Centre / McMaster U. Hamilton, on, Canada l8s 4l6 [email protected] T he previous general update of correspondence and manuscript acquisi­ tions appeared in Russellz n.s. 28, no. 2 (winter 2008–09): 162–70. There are 15 entries in the correspondence listing below, covering 38 items. Received in November 2009, the latest acquisition reported is number 1,606. The manuscript listing (...) of 2 items brings the total to 635 such entries since 1968. The latest manuscript acquisition is 1,601. Some items were received from other institutions, to whom McMaster Library is very grateful. The following abbre­ viations are used: L(s). or l(s). = letters(s); P(s). or p(s). = photocopies; p.c.(s). = post card(s); Ts. = typescript; tel. = telegram. Thanks are due to Carl Spadoni, Research Collections Librarian, for pursuing many of the leads whose fruition is evident here. There are still more original Russell documents to be found. correspondence [Anonymous] L. from BR, n.d., declin­ ing to write an article. Internet print. rec. acq. 1,577. Farr, Elliott 4 ls. and tel. from BR, 1944– 47 (incl. 2 to W.yR. White of White & Williams); 2 ls. from Patricia Russell to Farr and his wife, 1947, and l. to White, 1946; 6 ls. from White to Farr, 1946– 47, and l. from Farr to White, 1946. Freight bill and bill of lading, 1947; re storing and shipping of trunks and boxes. Draft typed l. or statement about Hitler in response to someone. c.1941 (“I would 1,000 times rather be dead than say Heil Hitler”). Found in Farr’s copy of An Inquiry into Meaning and Truth. Gift of Caroline Farr, whose parents who were 1943 neighbours of BR on Pennstone Road, Bryn Mawr, pa. rec. acq. 1,601. Freedom Defence Committee (H.yB. Gibson) L. from Josephine Hall on BR’s behalf, 31 Oct. 1946, encl. dona­ tion for typewriter; reply l. of thanks on behalf of the treasurer, 1 Nov. 1946. Ps., courtesy of International Institute for Social History. rec. acq. 1,599a. Guran, Henry L. from BR, 15 Feb. 1951 in response to a Toronto autograph re­ quest. Purchase. rec. acq. 1,603. Krumreig, William L. from BR, 3 Sept. 1960. Re Henry George. Krumreig’s in­ coming letter with BR’s reply written on the verso is in ra1 720. Internet print. rec. acq. 1,577. Lorenzen, Paul L. from BR, 22 Nov. 1948, on whether linguistic questions connect with politics; l. to BR, n.d. December 2, 2009 (5:28 pm) E:\CPBR\RUSSJOUR\TYPE2901\russell 29,1 060 red.wpd E:\CPBR\RUSSJOUR\TYPE2901\russell 29,1 060 red.wpd Recent Acquisitions 63 Bertrand Russell to Moritz Schlick, 5 March 1935, from the Canary Islands, where Russell had gone to recover from nervous exhaustion. December 2, 2009 (5:28 pm) E:\CPBR\RUSSJOUR\TYPE2901\russell 29,1 060 red.wpd E:\CPBR\RUSSJOUR\TYPE2901\russell 29,1 060 red.wpd 64 sheila turcon politics; l. to BR, n.d. Scans. Courtesy Scans. Courtesy of Philosophisches Archiv, Universität Konstanz. rec. acq. 1,598. Meijer, J.yB. L. from Allen and Unwin, 1924. L. from Harold F. Bing, 1924. Ps., courtesy of International Institute for Social History. rec. acq. 1,599b. Ransom, Harry Correspondence with William S. Livingston, House of El DieT (Lew Feldman) and Anton Felton concerning the sale of Russell’s papers in 1967 and the Newsweekz scandal; newsclippings. Ps., courtesy U. of Texas via Albert Lewis. rec. acq. 1,584. Rotblat, Joseph L. from BR, 6 July 1956. Follow-up to the Russell–Einstein Manifesto; formation of Pugwash. In­ ternet print. rec. acq. 1,577. Schlick, Moritz 2 ls. from BR, 1924, 1935 (see illustration); draft l. to, 1923; l. from Dora Russell on BR’s behalf, 1927. BR is unable to visit Vienna in 1924; OKEWz; [Nicod]; lecture tour of Austria and Scandinavia abandoned, 1935. Printed jpg images. Courtesy of Wiener Kreis Archiv, Haarlem, Nether­ lands. rec. acq. 1,597. Stott, R. Toole L. from Russell, 28 Sept. 1931, re the economic crisis and under­ standing currency and credit. Purchase. rec. acq... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:167 THE HUME LITERATURE FOR 1982 The Hume literature from 1925 to 1976 has been thoroughly covered in my book Fifty Years of Hume Scholarship: A Bibliographical Guide (Edinburgh University Press, 1978; £9.50), which also lists the main earlier writings on Hume. Publications of the years 1977 to 1981 were listed in Hume Studies in previous Novembers. What follows here will bring the record up to the end of (...) 1982. Readers are invited to inform me of any omissions, and to send me offprints of their own articles and reviews. The intention is to maintain a complete bibliographical record of critical work on Hume, by the regular publication in Hume Studies of an annual bibliography, with addenda consisting of items omitted through ignorance in previous years. References to recently-appearing reviews (of books from earlier lists) are given at the end. The following abbreviations of journal titles are used here: APQAmerican Philosophical Quarterly JHIJournal of the History of Ideas JHPJournal of the History of Philosophy JPJournal of Philosophy PASProceedings of the Aristotelian Society PBPhilosophical Books PQPhilosophical Quarterly PRPhilosophical Review RIPRevue Internationale de Philosophie RMReview of Metaphysics TLSTimes Literary Supplement Other abbreviations should be obvious enough, and mainly follow the British Standard (no. 4148). 168 AIKEN, H. D. 'The Originality of Hume's Theory of Obligation', Phil. & Phenomenol. Res. 42, 374-83. BADIA CABRERA, M. A. 'Milagro, testimonio y verdad. El significado de la crítica de Hume', Dialogos (Puerto Rico) 17, 37-52. BAIER, A. 'Hume's Account of our Absurd Passions', JP_ 79, 643-51. [652] BARON, M. 'Hume's Noble Lie: An Account of his Artificial Virtues', Can. J. Phil. 12, 539-55. BERRY, CJ. Hume, Hegel and Human Nature, pt. 2 (55124 ). The Hague, etc. [Hume Studies 9 (1983) 200-3] BERRY, CJ. 'Hume on Rationality in History and Social Life', History & Theory 21, 234-47. BUNZL, M. 'Humean Counterfactuals', JHP 20, 171-7. CALLICOTT, J. B. 'Hume's Is/Ought Dichotomy and the Relation of Ecology to Leopold's Land Ethic', Environmental Ethics 4, 163-74. CAPALDI, N., KING, J. & LIVINGSTON, D. 'The Hume Literature of the 1970s', Philosophical Topics 12, no. 3, 167-92. COLWELL, G.G. 'On Defining Away the Miraculous', Philosophy 57, 327-37. DAVIES, B. An Introduction to the Philosophy of Religion, 52-9 and 108-18. Oxford. DEL BARCO COLLAZOS, J. L. 'Evidencia y verdad en la epistemologia de Hume', Anuario filosófico 15, 175-84. DEL BARCO COLLAZOS, J. L. 'La teoría de la impresión en Hume', Anuario filosofico 15, 85-112. DRAPER, T. 'Hume and Madison: The Secrets of Federalist Paper No. 10', Encounter 58, (Feb.) 34-47. FARR, J. 'Humean Explanations in the Moral Sciences', Inquiry 25, 57-80. FERN, R. L. 'Hume's Critique of Miracles: An Irrelevant Triumph', Relig. Studies 18, 337-54. FITZPATRICK, J. 'Lonergan and Hume [I-IV: various aspects]', New Blackfriars 63, 122-30, 219-28, 275-86, 364-72. 169 FLAGE, D.E. 'Relative Ideas Revisited: A Reply to Thomas', Hume Studies 8, 158-71. FLAGE, D.E. 'Hume's Dualism', Nous 16, 527-41. FLEW, A. 'Another Idea of Necessary Connection', Philosophy 57, 487-94. FLEW, A. '"Hume on Space and Geometry": One Reservation ', Hume Studies 8, 62-5. [66-9] FORBES, D. 'Natural Law and the Scottish Enlightenment', in R. H. Campbell & A. S. Skinner, The Origins and Nature of the Scottish Enlightenment, 186204. Edinburgh. FORCE, J. E. 'Hume and Johnson on Prophecy and Miracles: Historical Context', JH_I 43, 463-75. FRIEMAN, J. 'Boswell Confronts Hume: An Encounter with the Great Infidel', Free Inquiry 2, 22-5. GALGAN, G.J. The Logic of Modernity, 118-36 ('Hume: The Breakdown of Certitude'). New York S London. HALL, R. 'The Hume Literature for 1981', Hume Studies 8, 172-7. HALLER, R. Urteile und Ereignisse, 76-85 ('Humes Analyse'). Munich. HAUSMAN, A. 'It Ain't Necessity, So... (with Apologies to George Gershwin)', Hume Studies 8, 87-101. HILL, E. 'Hume and the Delightful Tragedy Problem', Philosophy 57, 319-26. HOERSTER, N. 'David Hume', in N. Hoerster, Klassiker des philosophischen Denkens, vol. 2, 7-46. Munich. JONES, G. E. 'Vindication, Hume and Induction', Can. J. Phil. 12, 119-29. JONES, P. 'Laughter', PAS... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:russell: the Journal of Bertrand Russell Studies n.s. 34 (winter 2014–15): 131–4 The Bertrand Russell Research Centre, McMaster U. issn 0036–01631; online 1913–8032 c:\users\ken\documents\type3402\rj 3402 050 red.docx 2015-02-04 9:19 PM _ibliography NEW PERIODICAL ARTICLES BY RUSSELL Kenneth Blackwell here are 35 new C entries since 1993 for A Bibliography of Bertrand Russell, and more for all Parts of Vol. 2. With many thanks to several readers. C15.18a [RECONSTRUCTION OF (...) INTELLECTUAL INTERNATIONALISM AFTER THE WAR]. Svenska Dagbladet, Stockholm, 18 July 1915, sec. b, p. 5. Published under the general title “Det kulturella samarbetets återupptagande efter kriget” [The re-establishment of cultural cooperation after the war]. There is a subtitle : “Tre nya svar på Svenska Dagbladets världsenquête” [Three new responses to Svenska Dagbladet’s world enquiry].—Ms. (ra3 rec. acq. 1,325).—In English in Russell, n.s. 18 (1998): 141–3 (ed. K. Blackwell). C16.07a THE CASE OF MR. E. CHAPPELOW. The Manchester Guardian, 19 April 1916, p. 6. Six sentences, introduced thus: “The Hon. Bertrand Russell writes”.—Russell makes reference to the Everett case. C16.10a THE CASE OF THE CONSCIENTIOUS OBJECTOR. The Freethinker, 36 (14 May 1916): 310. “… the country is drifting into the infliction of serious persecution upon a large number of young men.…”—Reprinted, with two-thirds omitted, in Jim Herrick, Vision and Realism: a Hundred years of The Freethinker (London: Foote, 1982), pp. 51–2. C22.39 INSTINCT, HABIT, AND INTELLIGENCE. Hull Weekly Recorder, no. 1 (16 Dec. 1922): 6–9. Reprinted in Collected Papers 16 (in preparation). C23.10a BERTRAND RUSSELL PREDICTS U.S. WILL EVENTUALLY CONTROL THE ENTIRE WORLD. The Daily Argus, Mt. Vernon, ny, 7 March 1923, p. 3. Subtitled “Famous British Philosopher Declares America Will Conquer through Economic Causes What Others Have Tried to Win by Force”.—A note states: “Written exclusively for I.N.S.” (International News Service).—Reprinted in Collected Papers 16 (in preparation). C28.02a WHAT I THINK OF COMPANIONATE MARRIAGE. Children, the Magazine for Parents, Chicago, 3 (Feb. 1928): 17. Russell’s contribution—one of four under the title, the others being by Ernest R. Groves, Stephen S. Wise, and Anna Garlin Spencer, pp. 17, 47—is five sentences long.—Reprinted in Collected Papers 18 (in preparation). C28.02b [ADVICE ON WRITING]. The Daily Illini (U. of Illinois), Champaign, il, 12 Feb. 1928, p. 15. Letter to the author on developing a writing style, quoted fully in Newton York, q= 132 kenneth blackwell c:\users\ken\documents\type3402\rj 3402 050 red.docx 2015-02-04 9:19 PM “What Authors Advise”, ibid.—Part of Russell’s advice is to “read Gibbon all through, at least twice.” —Reprinted in Collected Papers 18 (in preparation). C32.39a MR. BERTRAND RUSSELL’S QUESTIONS. The Manchester Guardian, 27 June 1932, p. 10. Letter to a Coventry correspondent, under the title, “The Dismissed Teacher”. C34.36a ROMAN-CELTIC FARM SITE. The Times, 18 Sept. 1934, p. 7. Letter in “Points from Letters”, signed by John Russell, Telegraph House, Harting, Petersfield, referring to S. E. Winbolt’s “A Roman-Celtic Farm Site; Discovery near Harting, Sussex”, ibid., 10 Sept. 1934, p. 7. The writer states that his part was “not so great” as it appears in the account.—The composition of the letter is ascribed here to Bertrand Russell because a draft, with the exception of a phrase added later, is entirely in his fluent hand. That of his 13-year-old son is not present.—The draft was crossed out, and the verso became folio 1 of the ms. of “On Ceremony” (C34.48). C34.55a [THE AMERICAN LIBRARY OF NAZI BANNED BOOKS]. Jewish Daily Bulletin, New York, 11, no. 3,030 (23 Dec. 1934): 1. A telegram congratulating the Brooklyn Jewish Center for “inaugurating an American Library for Nazi burnt books”.—The allusion is to the Nazi bonfire of banned books on 10 May 1933.—The dinner celebrating the Library and mentioned in Russell’s telegram is the subject of Joseph Goldberg, “ ‘A Splendid and Historic Gathering’: Brooklyn Jewish Center Inaugurates Library of Nazi Banned books”, Brooklyn Jewish Center Review... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:russell: the Journal of Bertrand Russell Studies n.s. 34 (winter 2014–15): 131–4 The Bertrand Russell Research Centre, McMaster U. issn 0036–01631; online 1913–8032 c:\users\ken\documents\type3402\rj 3402 050 red.docx 2015-02-04 9:19 PM _ibliography NEW PERIODICAL ARTICLES BY RUSSELL Kenneth Blackwell here are 35 new C entries since 1993 for A Bibliography of Bertrand Russell, and more for all Parts of Vol. 2. With many thanks to several readers. C15.18a [RECONSTRUCTION OF (...) INTELLECTUAL INTERNATIONALISM AFTER THE WAR]. Svenska Dagbladet, Stockholm, 18 July 1915, sec. b, p. 5. Published under the general title “Det kulturella samarbetets återupptagande efter kriget” [The re-establishment of cultural cooperation after the war]. There is a subtitle : “Tre nya svar på Svenska Dagbladets världsenquête” [Three new responses to Svenska Dagbladet’s world enquiry].—Ms. (ra3 rec. acq. 1,325).—In English in Russell, n.s. 18 (1998): 141–3 (ed. K. Blackwell). C16.07a THE CASE OF MR. E. CHAPPELOW. The Manchester Guardian, 19 April 1916, p. 6. Six sentences, introduced thus: “The Hon. Bertrand Russell writes”.—Russell makes reference to the Everett case. C16.10a THE CASE OF THE CONSCIENTIOUS OBJECTOR. The Freethinker, 36 (14 May 1916): 310. “… the country is drifting into the infliction of serious persecution upon a large number of young men.…”—Reprinted, with two-thirds omitted, in Jim Herrick, Vision and Realism: a Hundred years of The Freethinker (London: Foote, 1982), pp. 51–2. C22.39 INSTINCT, HABIT, AND INTELLIGENCE. Hull Weekly Recorder, no. 1 (16 Dec. 1922): 6–9. Reprinted in Collected Papers 16 (in preparation). C23.10a BERTRAND RUSSELL PREDICTS U.S. WILL EVENTUALLY CONTROL THE ENTIRE WORLD. The Daily Argus, Mt. Vernon, ny, 7 March 1923, p. 3. Subtitled “Famous British Philosopher Declares America Will Conquer through Economic Causes What Others Have Tried to Win by Force”.—A note states: “Written exclusively for I.N.S.” (International News Service).—Reprinted in Collected Papers 16 (in preparation). C28.02a WHAT I THINK OF COMPANIONATE MARRIAGE. Children, the Magazine for Parents, Chicago, 3 (Feb. 1928): 17. Russell’s contribution—one of four under the title, the others being by Ernest R. Groves, Stephen S. Wise, and Anna Garlin Spencer, pp. 17, 47—is five sentences long.—Reprinted in Collected Papers 18 (in preparation). C28.02b [ADVICE ON WRITING]. The Daily Illini (U. of Illinois), Champaign, il, 12 Feb. 1928, p. 15. Letter to the author on developing a writing style, quoted fully in Newton York, q= 132 kenneth blackwell c:\users\ken\documents\type3402\rj 3402 050 red.docx 2015-02-04 9:19 PM “What Authors Advise”, ibid.—Part of Russell’s advice is to “read Gibbon all through, at least twice.” —Reprinted in Collected Papers 18 (in preparation). C32.39a MR. BERTRAND RUSSELL’S QUESTIONS. The Manchester Guardian, 27 June 1932, p. 10. Letter to a Coventry correspondent, under the title, “The Dismissed Teacher”. C34.36a ROMAN-CELTIC FARM SITE. The Times, 18 Sept. 1934, p. 7. Letter in “Points from Letters”, signed by John Russell, Telegraph House, Harting, Petersfield, referring to S. E. Winbolt’s “A Roman-Celtic Farm Site; Discovery near Harting, Sussex”, ibid., 10 Sept. 1934, p. 7. The writer states that his part was “not so great” as it appears in the account.—The composition of the letter is ascribed here to Bertrand Russell because a draft, with the exception of a phrase added later, is entirely in his fluent hand. That of his 13-year-old son is not present.—The draft was crossed out, and the verso became folio 1 of the ms. of “On Ceremony” (C34.48). C34.55a [THE AMERICAN LIBRARY OF NAZI BANNED BOOKS]. Jewish Daily Bulletin, New York, 11, no. 3,030 (23 Dec. 1934): 1. A telegram congratulating the Brooklyn Jewish Center for “inaugurating an American Library for Nazi burnt books”.—The allusion is to the Nazi bonfire of banned books on 10 May 1933.—The dinner celebrating the Library and mentioned in Russell’s telegram is the subject of Joseph Goldberg, “ ‘A Splendid and Historic Gathering’: Brooklyn Jewish Center Inaugurates Library of Nazi Banned books”, Brooklyn Jewish Center Review... (shrink)

人工と設計の花鳥風月。知覚し行為する生きものが住まう環境としての“世界”において、郵便ポストは実在するか?近代テクノロジーの観点を超えた生態学的環境と、ごく日常的な「ものども」のあり方を徹底的に問い直 す存在論の創出。本書では、心理学、認知科学、知識工学、哲学を専門とする著者が集まり、それぞれが独自の視点から環境について考察している。.

皮膚は自己と環境との境界である。家は公と私を隔て、国境は国を隔てる。これら境界は本当は一体何を隔て、われわれに何を強いているのか。境界を越えるという経験はいかなる意味をもちうるのか。境界を越えて、われ われはいかに他者と出会い、世界とつながることができるのか―。幾層もの境界を徹底的に問い直し、内/外を無効化する流動的でダイナミックな存在のあり方を提示する。身体・自己・世界の関係を考察してきた著者が、 流体の存在論なる新境地に挑む。.

感情の取り締まり(ポリシング)、トランス排除、宗教右派からポストトゥルースまで。透徹した思考に貫かれた論考群。.

「人に親切にしろ」「故郷を愛せよ」「社会のマナーは守ろう」。学校の道徳の時間に教えられてきたのは、このような徳育でしかなく、こういった言葉はもう十分、聞き飽きた。では、いまの時代・社会にフィットした道 徳とは何か?また、それをどのようにして、子どもたちに教えたらよいのか?本書では、様々な倫理学の知見を掘り下げながら、哲学的にその本質に迫っていく。ひとりでは生き延びることができない時代に、他者と共に生 きるための道徳が求められる。.

立法・法改正論争が盛んな現代日本の法理論の背後にあるものを理解するため、幕末から新憲法までの法思想の道筋を辿る。.

Livres Une généalogie du spiritualisme français. Aux sources du bergsonisme : Ravaisson et la métaphysique, La Haye, Martinus Nijhoff, 1969, coll. « Archives internationales d’Histoire des Idées », no 30, X, 278 p. [2e éd. sous le titre Ravaisson et la métaphysique, Paris, Vrin, 1997]. Hegel et le destin de la Grèce, Paris, Vrin, 1975, coll. « Bibliothèque d’Histoire de la Philosophie », 379 p. ; 2e éd. 2005. La métaphysique à la limite. Cinq études sur Heidegger (en collaboration avec (...) Jean-F... (shrink)

Designed for classroom use, this authoritative anthology presentskey selections from the best contemporary work in philosophy offilm. The featured essays have been specially chosen for theirclarity, philosophical depth, and consonance with the current movetowards cognitive film theory Eight sections with introductions cover topics such as thenature of film, film as art, documentary cinema, narration andemotion in film, film criticism, and film's relation to knowledgeand morality Issues addressed include the objectivity of documentary films,fear of movie monsters, and moral questions surrounding the (...) viewingof pornography Replete with examples and discussion of moving picturesthroughout. (shrink)

(2008). Editorial Board/Publication Information. History of European Ideas: Vol. 34, No. 3, pp. IFC-IFC.

Traduction de [Twardowski 1927, 446–447] Thèses formulées d’après la conférence intitulée : Le Concept d’imputabilité pénale à la lumière de la psychologie, prononcée lors d’une réunion de la Société juridique de Lvov, le 25 mars 1899 L’imputation au sens du droit pénal est un cas particulier de l’imputation prise au sens large, c’est-à-dire de l’imputation morale. L’imputation morale contient une évaluation éthique de l’acte imputé, le qualifiant ou bien d’interdit, ou bien de permis, ou bie...

Ouvrages Le supplément au voyage de Bougainville et autres œuvres morales de Diderot, édition présentée et commentée, avec un dossier, Paris, Agora, Presses Pocket, 1992. Le trésor perdu. Hannah Arendt, l’intelligence de l’action politique, Paris, Payot, 1999. Un monde commun. Pour une cosmo-politique des conflits, Paris, Seuil, 2003. Le maléfice de la vie à plusieurs. La politique est-elle vouée à l’échec?, Paris, Bayard, 2012. Ouvrages collectifs Avec J. Message et J. Roman, À quoi p...

Journées Dilthey.Les 3-4 décembre 1999 ont eu lieu à la Maison de la Recherche de Lille deux journées de travail consacrées à Wilhelm Dilthey, organisées dans le cadre du réseau thématique « Herméneutique, Mythe et Image », associant les Universités de Bourgogne-Dijon, de Lille 3, l’Université Libre de Bruxelles, les Universités de Lausanne, de Neuchâtel et de Zürich ainsi que l’Institut Catholique de Paris. Organisées par André Laks et Denis Thouard, ces journées se donnaient pour objectif u..

Ont été sollicités pour évaluer les articles de ce numéro : Dominique Abry Florentina Fredet Enrica Galazzi Bertrand Lauret Régine Llorca Grégory Miras Chiara Molinari Christos Nikou (responsable du c...

Quia inter doctores est magna dissentio (Université de Parme, 17-18 mai 2002) Au cours de ces dernières années, les études sur la philosophie naturelle au XIVe siècle se sont multipliées, modifiant profondément la vision traditionnelle d'un siècle marqué par le nominalisme d'Ockham et de J. Buridan. L'UMR « Savoirs et Textes » et l'Université de Parme (J.Celeyrette et S.Caroti) ont donc pris l'initiative d'organiser les 17 et 18 mai 2002 à l’Université de Parme un colloque international.

Journée d'étude « Pour une pensée des actes d'images » Organisée dans le cadre du programme PHC Tournesol Lille-Gand inter-laboratoires « La preuve Scientifique entre argumentation et image ». Responsable : Anne-Lise Rey. Lille, MESHS, Vendredi 26 septembre 2014. Programme 10h30 : Isabelle Pantin : « Les Theoricae novae planetarum et l'évolution de leurs schémas : enjeu et signification d'un progrès vers l'exactitude » 11h15 : discussion 14h : Guy Claessens : « Imagining...