Results for 'Graaf Rieke'

142 found
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  1.  11
    Injustice in Bioethics Research Funding: Going Further Upstream.Himani Bhakuni, Rieke van der Graaf & Seye Abimbola - 2022 - American Journal of Bioethics 22 (1):33-35.
    Fabi and Goldberg have helpfully shed some light on the wrongs perpetuated by the current funding architecture on research, sponsorship, and career development in the field of bioethics. The...
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  2.  20
    The ethics of ethics conferences: Is Qatar a desirable location for a bioethics conference?Rieke van der Graaf, Karin Jongsma, Suzanne van de Vathorst, Martine de Vries & Ineke Bolt - 2023 - Bioethics 37 (4):319-322.
    The next World Congress of Bioethics will be held in Doha, Qatar. Although this location provides opportunities to interact with a more culturally diverse audience, to advance dialogue between cultures and religions, offer opportunities for mutual learning, there are also huge moral concerns. Qatar is known for violations of human rights ‐ including the treatment of migrant workers and the rights of women ‐ corruption, criminalization of LGBTQI+ persons, and climate impact. Since these concerns are also key (bio)ethical concern we (...)
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  3.  19
    What constitutes a reasonable compensation for non-commercial oocyte donors: an analogy with living organ donation and medical research participation.Emy Kool, Rieke van der Graaf, Annelies Bos, Bartholomeus Fauser & Annelien Bredenoord - 2019 - Journal of Medical Ethics 45 (11):736-741.
    There is a growing consensus that the offer of a reasonable compensation for oocyte donation for reproductive treatment is acceptable if it does not compromise voluntary and altruistically motivated donation. However, how to translate this ‘reasonable compensation’ in practice remains unclear as compensation rates offered to oocyte donors between different European Union countries vary significantly. Clinics involved in oocyte donation, as well as those in other medical contexts, might be encouraged in calculating a more consistent and transparent compensation for donors (...)
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  4.  47
    What is the best standard for the standard of care in clinical research?Rieke van der Graaf & Johannes J. M. van Delden - 2009 - American Journal of Bioethics 9 (3):35 – 43.
    During the past decennium, one of the main issues discussed in research ethics has been focused on the care that should be provided to the control group in a clinical trial. This discussion is also called the standard of care debate . Current international research ethics guidelines contain a wide variety of standards for the standard of care—including the provision of the highest attainable, the best available, the best current, a proven , and an established effective treatment. In this article, (...)
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  5.  73
    On using people merely as a means in clinical research.Rieke van der Graaf & Johannes J. M. van Delden - 2010 - Bioethics 26 (2):76-83.
    It is often argued that clinical research should not violate the Kantian principle that people must not be used merely as a means for the purposes of others. At first sight, the practice of clinical research itself, however, seems to violate precisely this principle: clinical research is often beneficial to future people rather than to participants; even if participants benefit, all things considered, they are exposed to discomforts which are absent both in regular care for their diseases and in other (...)
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  6.  20
    Toward a “Post-Posthuman Dignity Area” in Evaluating Emerging Enhancement Technologies.Annelien L. Bredenoord, Rieke van der Graaf & Johannes Jm van Delden - 2010 - American Journal of Bioethics 10 (7):55-57.
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  7.  46
    Clarifying appeals to dignity in medical ethics from an historical perspective.Rieke van der Graaf & Johannes Jm van Delden - 2008 - Bioethics 23 (3):151-160.
    ABSTRACT Over the past few decades the concept of (human) dignity has deeply pervaded medical ethics. Appeals to dignity, however, are often unclear. As a result some prefer to eliminate the concept from medical ethics, whereas others try to render it useful in this context. We think that appeals to dignity in medical ethics can be clarified by considering the concept from an historical perspective. Firstly, on the basis of historical texts we propose a framework for defining the concept in (...)
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  8.  33
    The Social Value of Pragmatic Trials.Shona Kalkman, Ghislaine van Thiel, Rieke van der Graaf, Mira Zuidgeest, Iris Goetz, Diederick Grobbee & Johannes van Delden - 2017 - Bioethics 31 (2):136-143.
    Pragmatic trials aim to directly inform health care decision-making through the collection of so-called ‘real world data’ from observations of comparative treatment effects in clinical practice. In order to ensure the applicability and feasibility of a pragmatic trial, design features may be necessary that deviate from standard research ethics requirements. Examples are traditional requirements to seek written informed consent and to perform extensive data and safety monitoring. Proposals for deviations from standard research ethics practice have resulted in controversy about their (...)
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  9.  19
    The Duty to Support Learning Health Systems: A Broad Rather than a Narrow Interpretation.Rieke van der Graaf, Wouter van Dijk, Sara J. M. Laurijssen, Ewoud Schuit, Diederick E. Grobbee & Martine C. de Vries - 2021 - American Journal of Bioethics 21 (1):14-16.
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  10.  11
    The Duty to Support Learning Health Systems: A Broad Rather than a Narrow Interpretation.Rieke van der Graaf, Wouter van Dijk, Sara J. M. Laurijssen, Ewoud Schuit, Diederick E. Grobbee & Martine C. De Vries - 2020 - American Journal of Bioethics 21 (1):14-16.
    As of October 23, 2020, almost 42 million cases of COVID-19 have been reported globally. Although many different treatments have been applied in infected...
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  11.  19
    How the CIOMS guidelines contribute to fair inclusion of pregnant women in research.Rieke van der Graaf, Indira S. E. Van der Zande & Johannes J. M. Van Delden - 2018 - Bioethics 33 (3):377-383.
    As early as 2002, CIOMS stated that pregnant women should be presumed eligible for participation in research. Despite this position and calls of other well‐recognized organizations, the health needs of pregnant women in research remain grossly under‐researched. Although the presumption of eligibility remains unchanged, the revision of the 2002 CIOMS International ethical guidelines for biomedical research involving human subjects involved a substantive rewrite of the guidance on research with pregnant women and related guidelines, such as those on fair inclusion and (...)
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  12.  16
    How the CIOMS guidelines contribute to fair inclusion of pregnant women in research.Rieke van der Graaf, Indira S. E. van der Zande & Johannes J. M. van Delden - 2018 - Bioethics 33 (3):377-383.
    As early as 2002, CIOMS stated that pregnant women should be presumed eligible for participation in research. Despite this position and calls of other well‐recognized organizations, the health needs of pregnant women in research remain grossly under‐researched. Although the presumption of eligibility remains unchanged, the revision of the 2002 CIOMS International ethical guidelines for biomedical research involving human subjects involved a substantive rewrite of the guidance on research with pregnant women and related guidelines, such as those on fair inclusion and (...)
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  13.  45
    Vulnerability of pregnant women in clinical research.Indira S. E. Van der Zande, Rieke van der Graaf, Martijn A. Oudijk & Johannes J. M. Van Delden - 2017 - Journal of Medical Ethics 43 (10):657-663.
    Background Notwithstanding the need to produce evidence-based knowledge on medications for pregnant women, they remain underrepresented in clinical research. Sometimes they are excluded because of their supposed vulnerability, but there are no universally accepted criteria for considering pregnant women as vulnerable. Our aim was to explore whether and if so to what extent pregnant women are vulnerable as research subjects. Method We performed a conceptual and empirical analysis of vulnerability applied to pregnant women. Analysis A conceptual analysis supports Hurst's definition (...)
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  14.  11
    The Ethics of Ethics Conferences: Enhancing Further Transparency.Martine Charlotte de Vries & Rieke van der Graaf - 2024 - American Journal of Bioethics 24 (4):41-44.
    We appreciate that the theme “ethics of ethics conferences” that we introduced in 2023 (Van der Graaf et al. 2023) was echoed by the previous and current presidents of the International Association...
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  15.  25
    Conflating Scientific With Clinical Considerations.Rieke van der Graaf & Johannes J. M. van Delden - 2009 - American Journal of Bioethics 9 (9):58-59.
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  16.  31
    Response to Open Peer Commentaries on “What is The Best Standard for the Standard of Care in Clinical Research?”.Rieke van der Graaf & Johannes J. M. van Delden - 2009 - American Journal of Bioethics 9 (6-7):7-8.
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  17.  21
    Vulnerability of pregnant women in clinical research.Indira S. E. van der Zande, Rieke van der Graaf, Martijn A. Oudijk & Johannes J. M. van Delden - 2017 - Journal of Medical Ethics 43 (10):657-663.
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  18.  38
    A qualitative study on acceptable levels of risk for pregnant women in clinical research.Indira S. E. Van der Zande, Rieke van der Graaf, Martijn A. Oudijk & Johannes J. M. van Delden - 2017 - BMC Medical Ethics 18 (1):35.
    There is ambiguity with regard to what counts as an acceptable level of risk in clinical research in pregnant women and there is no input from stakeholders relative to such research risks. The aim of our paper was to explore what stakeholders who are actively involved in the conduct of clinical research in pregnant women deem an acceptable level of risk for pregnant women in clinical research. Accordingly, we used the APOSTEL VI study, a low-risk obstetrical randomised controlled trial, as (...)
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  19.  26
    Voluntary Informed Consent in Paediatric Oncology Research.Sara A. S. Dekking, Rieke Van Der Graaf & Johannes J. M. Van Delden - 2015 - Bioethics 30 (6):440-450.
    In paediatric oncology, research and treatments are often closely combined, which may compromise voluntary informed consent of parents. We identified two key scenarios in which voluntary informed consent for paediatric oncology studies is potentially compromised due to the intertwinement of research and care. The first scenario is inclusion by the treating paediatric oncologist, the second scenario concerns treatments confined to the research context. In this article we examine whether voluntary informed consent of parents for research is compromised in these two (...)
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  20.  12
    How Should the Precautionary Principle Apply to Pregnant Women in Clinical Research?Indira S. E. van der Zande, Rieke van der Graaf, Martijin A. Oudijk & Johannes J. M. van Delden - 2021 - Journal of Medicine and Philosophy 46 (5):516-529.
    The precautionary principle is often invoked in relation to pregnant women and may be one of the underlying reasons for their continuous underrepresentation in clinical research. The principle is appealing, because potential fetal harm as a result of research participation is considered to be serious and irreversible. In our paper, we explore through conceptual analysis whether and if so how the precautionary principle should apply to pregnant women. We argue that the principle is a decision-making strategy underlying risk-benefit decisions in (...)
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  21.  26
    Voluntary Informed Consent in Paediatric Oncology Research.Sara A. S. Dekking, Rieke Van Der Graaf & Johannes J. M. Van Delden - 2016 - Bioethics 30 (5):440-450.
    In paediatric oncology, research and treatments are often closely combined, which may compromise voluntary informed consent of parents. We identified two key scenarios in which voluntary informed consent for paediatric oncology studies is potentially compromised due to the intertwinement of research and care. The first scenario is inclusion by the treating paediatric oncologist, the second scenario concerns treatments confined to the research context. In this article we examine whether voluntary informed consent of parents for research is compromised in these two (...)
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  22.  10
    The boundary problem: Defining and delineating the community in field trials with gene drive organisms.Nienke de Graeff, Isabelle Pirson, Rieke van der Graaf, Annelien L. Bredenoord & Karin R. Jongsma - 2023 - Bioethics 37 (6):600-609.
    Despite widespread and worldwide efforts to eradicate vector-borne diseases such as malaria, these diseases continue to have an enormous negative impact on public health. For this reason, scientists are working on novel control strategies, such as gene drive technologies (GDTs). As GDT research advances, researchers are contemplating the potential next step of conducting field trials. An important point of discussion regarding these field trials relates to who should be informed, consulted, and involved in decision-making about their design and launch. It (...)
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  23.  34
    Voluntary Informed Consent Is Not Risk Dependent.Sara A. S. Dekking, Rieke van der Graaf, C. Michel Zwaan & Johannes J. M. van Delden - 2019 - American Journal of Bioethics 19 (4):33-35.
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  24.  8
    Issues in the Use of Stepped Wedge Cluster and Alternative Designs in the Case of Pandemics.Ingeborg van der Tweel & Rieke van der Graaf - 2013 - American Journal of Bioethics 13 (9):23-24.
  25.  16
    A qualitative study on acceptable levels of risk for pregnant women in clinical research.Indira S. E. van der Zande, Rieke van der Graaf, Martijn A. Oudijk & Johannes J. M. van Delden - 2017 - BMC Medical Ethics 18 (1).
    BackgroundThere is ambiguity with regard to what counts as an acceptable level of risk in clinical research in pregnant women and there is no input from stakeholders relative to such research risks. The aim of our paper was to explore what stakeholders who are actively involved in the conduct of clinical research in pregnant women deem an acceptable level of risk for pregnant women in clinical research. Accordingly, we used the APOSTEL VI study, a low-risk obstetrical randomised controlled trial, as (...)
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  26.  52
    Toward a “Post-Posthuman Dignity Area” in Evaluating Emerging Enhancement Technologies.Johannes J. M. van Delden, Rieke van der Graaf & Annelien L. Bredenoord - 2010 - American Journal of Bioethics 10 (7):55-57.
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  27.  15
    Stimulating solidarity to improve knowledge on medications used during pregnancy: A contribution from the ConcePTION project.Johannes J. M. van Delden, Miriam C. J. M. Sturkenboom, Rieke van der Graaf & Marieke J. Hollestelle - 2023 - BMC Medical Ethics 24 (1):1-9.
    BackgroundPregnant people have been overlooked or excluded from clinical research, resulting in a lack of scientific knowledge on medication safety and efficacy during pregnancy. Thus far, both the opportunities to generate evidence-based knowledge beyond clinical trials and the role of pregnant people in changing their status quo have not been discussed. Some scholars have argued that for rare disease patients, for whom, just like pregnant people, a poor evidence base exists regarding treatments, solidarity has played an important role in addressing (...)
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  28. Social Value.Hans van Delden & Rieke van der Graaf - 2021 - In Graeme T. Laurie (ed.), The Cambridge handbook of health research regulation. New York, NY: Cambridge University Press.
     
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  29.  97
    Power Difference and Risk Perception: Mapping Vulnerability within the Decision Process of Pregnant Women towards Clinical Trial Participation in an Urban Middle‐Income Setting.C. den Hollander Geerte, lBrowne Joyce, Arhinful Daniel, Graaf Rieke & Klipstein-Grobusch Kerstin - 2016 - Developing World Bioethics:68-75.
    To address the burden of maternal morbidity and mortality in low‐ and middle‐income countries (LMICs), research with pregnant women in these settings is increasingly common. Pregnant women in LMIC‐context may experience vulnerability related to giving consent to participate in a clinical trial. To recognize possible layers of vulnerability this study aims to identify factors that influence the decision process towards clinical trial participation of pregnant women in an urban middle‐income setting. This qualitative research used participant observation, in‐depth interviews, and focus (...)
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  30.  25
    Historicizing Strong Metaphors: A Challenge for Conceptual History.Rieke Schäfer - 2012 - Contributions to the History of Concepts 7 (2):28-51.
    The debate between metaphor theorists and conceptual historians has been intensifying in recent years. This article takes this debate beyond the bias toward Blumenberg's metaphorology, and starts from the interaction view of metaphor as formulated by Max Black. The article opens with a theoretical framework that reformulates Black's notions of metaphorical resonance and emphasis. It adapts them to the requirements of Conceptual History, and adds a third, historical criterion for metaphoricity. It then applies these suggestions to the history of the (...)
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  31.  23
    Aristotle and the copula.Riek Bennekovanm - 1986 - Journal of the History of Philosophy 24 (1).
  32.  25
    Aristotle and the Copula.Riek van Bennekom - 1986 - Journal of the History of Philosophy 24 (1):1-18.
  33. Konstanten paganer Ethik bei Augustinus.Rudolf Rieks - 2003 - In Peter Bruns (ed.), Von Athen nach Bagdad: zur Rezeption griechischer Philosophie von der Spätantike bis zum Islam. Bonn: Borengässer.
     
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  34. UNESCO, intangible heritage and sustainable development-the reorientation of a convention.Rieks Smeets - 2024 - In Chiara Bortolotto & Ahmed Skounti (eds.), Intangible cultural heritage and sustainable development: inside a UNESCO Convention. New York, NY: Routledge.
     
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  35.  3
    It is all about integrity, stupid: studies on, about or inspired by the work of Leo Huberts.Gjalt de Graaf (ed.) - 2019 - The Hague, the Netherlands: Eleven International Publishing.
    This book contains 26 studies on the integrity of governance, by scholars from around the world. The studies are on, about or inspired by Leo Huberts, the famous integrity scholar.
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  36.  8
    Tractable Morality.Gjalt De Graaf - 2005 - Journal of Business Ethics 60 (1):1 - 15.
    This article discusses five propositions about managerial moral tractability - that is, a morality that is amenable to the complexity of managers' continual pressure to decide and act - in their customer relations. The propositions come from the comparison of three case studies of different types of managers. To analyze the morality of managers, discursive practices of managers are studied. At the end of the article also some consideration is given to "information strategies" of managers, in relation to their tractable (...)
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  37.  5
    Discourse Theory and Business Ethics. The Case of Bankers' Conceptualizations of Customers.Gjalt De Graaf - 2001 - Journal of Business Ethics 31 (4):299 - 319.
    Within discourse theory, language is seen as constitutive of reality. Furthermore, facts and values are viewed as inseparable. This has consequences for business ethics. In this paper the relationship between discourse theory and business ethics is discussed. Both the descriptive and prescriptive aspects of business ethics are taken into account. Furthermore, an example of an empirical study is presented. A discourse analysis is concluded to answer the questions of how bankers in Holland conceptualize and thus treat their customers and whether (...)
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  38.  18
    Ethics and Behavioural Theory: How Do Professionals Assess Their Mental Models?Frank Graaf - 2019 - Journal of Business Ethics 157 (4):933-947.
    The role and ethics of professionals in business and economics have been questioned, especially after the financial crisis of 2008. Some suggest a reorientation using concepts such as craftsmanship. In this article, I will explore professional practices within the context of behavioural theory and business ethics. I suggest that scholars of behavioural theory need a strategy to deal with normative questions to meet their ambition of practical relevance. Evidence-based management (EBMgt), a recent behavioural approach, may assist business ethics scholars in (...)
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  39.  52
    Ethics and Behavioural Theory: How Do Professionals Assess Their Mental Models?Frank Jan de Graaf - 2019 - Journal of Business Ethics 157 (4):933-947.
    The role and ethics of professionals in business and economics have been questioned, especially after the financial crisis of 2008. Some suggest a reorientation using concepts such as craftsmanship. In this article, I will explore professional practices within the context of behavioural theory and business ethics. I suggest that scholars of behavioural theory need a strategy to deal with normative questions to meet their ambition of practical relevance. Evidence-based management, a recent behavioural approach, may assist business ethics scholars in understanding (...)
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  40.  11
    Clarifying Appeals to Dignity in Medical Ethics From an Historical Perspective.Rieke Vandergraaf - 2009 - Bioethics 23 (3):151-160.
    Over the past few decades the concept of (human) dignity has deeply pervaded medical ethics. Appeals to dignity, however, are often unclear. As a result some prefer to eliminate the concept from medical ethics, whereas others try to render it useful in this context. We think that appeals to dignity in medical ethics can be clarified by considering the concept from an historical perspective. Firstly, on the basis of historical texts we propose a framework for defining the concept in medical (...)
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  41.  70
    Veterinarians’ Discourses on Animals and Clients.Gjalt de Graaf - 2005 - Journal of Agricultural and Environmental Ethics 18 (6):557-578.
    Veterinarians have obligations towards both the animals they treat and their clients, the owners of the animals. With both groups, veterinarians have complicated relations; many times the interests of both groups conflict. In this article, using Q-methodology as a method for discourse analysis, the following question is answered: How do Dutch practicing veterinarians conceptualize animals and their owners and their professional responsibility towards both? The main part of the article contains descriptions of four different discourses on animals and their owners (...)
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  42. Tractable morality.Gjalt de Graaf - 2005 - Journal of Business Ethics 60 (1):1-15.
    This article discusses five propositions about managerial moral tractability -- that is, a morality that is amenable to the complexity of managers’ continual pressure to decide and act -- in their customer relations. The propositions come from the comparison of three case studies of different types of managers. To analyze the morality of managers, discursive practices of managers are studied. At the end of the article also some consideration is given to “information strategies” of managers, in relation to their tractable (...)
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  43.  22
    The judicial dialogue.Richard D. Rieke - 1991 - Argumentation 5 (1):39-55.
    A variety of theoretical positions are emerging to explain the judicial process from such perspectives as hermeneutics, semiotics, critical theory and argumentation/rhetoric. They ask such questions as these: What is the source of judicial authority? How do judges arrive at their decisions? By what logic are decisions to be tested? In this essay I argue that a focus on decisions and their justifications alone masks the broader process in which judges, along with all the other relevant groups, engage in a (...)
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  44.  33
    Discourse theory and business ethics. The case of bankers' conceptualizations of customers.Gjalt de Graaf - 2001 - Journal of Business Ethics 31 (4):299-319.
    Within discourse theory, language is seen as constitutive of reality. Furthermore, facts and values are viewed as inseparable. This has consequences for business ethics. In this paper the relationship between discourse theory and business ethics is discussed. Both the descriptive and prescriptive aspects of business ethics are taken into account. Furthermore, an example of an empirical study is presented. A discourse analysis is conducted to answer the questions of how bankers in Holland conceptualize and thus treat their customers and whether (...)
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  45.  11
    Situated and Historized Making Sense of Meaning: Implications for Radicalization.Beatrice A. De Graaf & Kees van den Bos - 2020 - Evolutionary Studies in Imaginative Culture 4 (1):59-62.
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  46.  20
    Long-term evaluation of a social robot in real homes.Maartje M. A. de Graaf, Somaya Ben Allouch & Jan A. G. M. van Dijk - 2016 - Interaction Studies. Social Behaviour and Communication in Biological and Artificial Systemsinteraction Studies / Social Behaviour and Communication in Biological and Artificial Systemsinteraction Studies 17 (3):461-490.
    This study aims to contribute to emerging human-robot interaction research by adding longitudinal findings to a limited number of long-term social robotics home studies. We placed 70 robots in users’ homes for a period of up to six months, and used questionnaires and interviews to collect data at six points during this period. Results indicate that users’ evaluations of the robot dropped initially, but later rose after the robot had been used for a longer period of time. This is congruent (...)
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  47.  43
    Clarifying appeals to dignity in medical ethics from an historical perspective.Riekeder Graaf & Johannes Jmdelden - 2009 - Bioethics 23 (3):151-160.
    Over the past few decades the concept of (human) dignity has deeply pervaded medical ethics. Appeals to dignity, however, are often unclear. As a result some prefer to eliminate the concept from medical ethics, whereas others try to render it useful in this context. We think that appeals to dignity in medical ethics can be clarified by considering the concept from an historical perspective. Firstly, on the basis of historical texts we propose a framework for defining the concept in medical (...)
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  48.  17
    Discourse and descriptive business ethics.Gjalt De Graaf - 2006 - Business Ethics, the Environment and Responsibility 15 (3):246-258.
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  49.  37
    Using brain stimulation to disentangle neural correlates of conscious vision.Tom A. de Graaf & Alexander T. Sack - 2014 - Frontiers in Psychology 5.
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  50.  17
    The ethos of business students.Jelle Baardewijk & Gjalt Graaf - 2020 - Business Ethics: A European Review 30 (2):188-201.
    Business schools are the “nurseries” of the corporate world. This article offers an empirical analysis of the business student ethos on the basis of research conducted at three Dutch universities. A theoretical framework in the tradition of virtue ethics and dubbed “moral ethology” is used to identify the values business schools convey to their students. The central research question is: What types of ethos do Dutch business students have? Forty‐three undergraduate students participated in Q‐methodological research, a mixed qualitative–quantitative small‐sample method. (...)
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