In the mammalian central nervous system (CNS), each neuron receives signals from other neurons through numerous synapses located on its cell body and dendrites. Molecules involved in the postsynaptic signaling pathways need to be targeted to the appropriate subcellular domains at the right time during both synaptogenesis and the maintenance of synaptic functions. The presence of messenger RNAs (mRNAs) in dendrites offers a mechanism for synthesizing the appropriate molecules at the right place in response to local extracellular stimuli. Several dendritic (...) mRNAs have been identified, and the mechanisms controlling their localization are beginning to be understood. In many cell types, controls on mRNA stability play an important role in the regulation of gene expression, but it is unclear to what extent this type of control operates in dendrites. The regulation of protein synthesis and the control of mRNA stability in dendrites could have important implications for neuronal function. BioEssays 20:70–78, 1998. © 1998 John Wiley & Sons, Inc. (shrink)

ObjectiveTo explore the relationship between adolescents’ social mobility belief and their learning engagement, as well as the mediating effect of achievement goal orientation and the moderating effect of psychological capital.MethodA sample of 895 adolescents from Hunan, Jiangxi, Hainan, Henan, and Guangdong provinces were assessed using the social mobility belief questionnaire, the achievement goal orientation questionnaire, the adolescents’ psychological capital questionnaire, and the adolescents’ learning engagement questionnaire.ResultsFirst, adolescents’ social mobility belief was positively related to their learning engagement ; Second, the two (...) achievement goal orientations-mastery goal orientations and performance goal orientations-had mediating effects between social mobility belief and learning engagement ; Third, the relationship between achievement goal orientation and learning engagement was regulated by psychological capital. Adolescents with high psychological capital had higher learning engagement.ConclusionAdolescents’ social mobility belief can directly affect their learning engagement, and it can also indirectly affect their learning engagement through achievement goal orientation moderated by their level of psychological capital. Our findings highlighted the importance of providing adolescents with guidance in setting up positive social values and definitions of success while stimulating their psychological capital as a part of the teaching process. (shrink)

Ben shu yan jiu zhong guo li shi shang jia zhi si xiang de yan bian he jia zhi chuan tong de xing cheng, bing zai ci ji chu shang ti chu xin shi dai zhong guo jia zhi ge ming de mu biao he ren wu.

Based on its productionguideline, organic agriculture has set foritself the goals of minimizing all forms ofpollution and maintaining sustainability of thefarming system. By striving for these goals,organic farming meets the demands of anincreasing number of consumers who are criticalof conventional production methods. This papergives an overview of the present state of theart in the different issues. Possibilities ofand limitations in performing the self-aimedgoals under the basic standards of organicagriculture are discussed. Concerningenvironmental protection, in general, the riskof adverse environmental effects is (...) lower withorganic than with conventional farming methods,though not necessarily so; with reference tosoil fertility and nutrient management, organicfarming is suited to improve soil fertility andnutrient management markedly on the farm level;regarding biodiversity, comparison studies showthat organic farming has more positive effectson biodiversity conservation; in relation toproduct quality, under the basic standards oforganic farming, there is no sufficientevidence for a system-related effect on productquality due to the production method. (shrink)

The earliest extant mathematical books from China contain a lot of problems and data about grains. They also betray a close relationship with imperial bureaucracy in this respect. Indeed, these texts quote administrative regulations about grains. For instance, the Book on mathematical procedures 筭數書, found in a tomb sealed ca. 186 BCE, has a section in common with the “regulations on granaries” from the Qin statutes in eighteen domains, known thanks to slips excavated at Shuihudi. Mathematical writings also deal with (...) official vessels used to measure grains. They cast light on statements from, and practices evidenced by, official histories and administrative documents. This article addresses the following issues. Which information about the concrete management of grains can we derive from mathematical writings in relation to administrative documents? Which data can we find in these writings about continuities and changes in the management of grains in the time span between the Qin and Han dynasties? In particular, how can we account for the fact that in a later mathematical text, namely, The Nine Chapters, probably completed in the first century CE, there was a change in the form in which the data about grain equivalences were given, by comparison with the “regulations on granaries”? Finally, what do our conclusions imply with respect to the nature of the earliest extant mathematical writings. In this article, we gather the various types of statement that mathematical writings contain about grains and offer several elements of interpretation for the “regulations on granaries” and the related text in The Nine Chapters. From this perspective, we offer several hypotheses about the management of grain in the Qin and Han dynasties. (shrink)

Not for the academic value of some of the situational events, often with a comprehensive, decisive, Yan'an new philosophy will the home of its columns. Will establish a new philosophy, a lot of grand strategy is one of the actions in Yan'an. This paper examines a new philosophy will be the basic process, an analysis of its membership and the subsequent effects, assessing its characteristics in the formation of contemporary Chinese culture, the unique role, made ​​a number of issues need (...) to be further explored. This paper shows that the new philosophy will not academics, but the educational organization. It is the ideology of expert training, knowledge and control of legal rights, the implementation of the regulatory action of self-sufficiency and closed culture strategy. New philosophy will be mainly in the construction and maintenance of highly exclusive mode of thinking to make contributions, as the full value of its effect remains to be thorough and reasonable debate. Some situational events, which have been neglected by academics, may be of significant importance. The Yan'an New Philosophy Association is an example. Its establishment was one of the ambitious strategic actions of the CCP in Yan'an. This paper examines the process of the YNPA's establishment, analyses the composition of its membership, assesses its unique effect on the formation of contemporary Chinese ideology, and raises some issues that are in need of further research. This study shows that the YNPA was an educational institution instead of an academic society, and that the experts in ideology it produced had exclusive power in the cultural domain and implemented the party's cultural policies. We can see that the YNPA greatly contributed to the construction and maintenance of a high degree of cultural exclusivity. A full picture of this association, however, requires much more in-depth studies. (shrink)

Today, modern large-scale production has created a real life world for people. People's life is so greatly dominated by production that we can say people's life is the life being produced. The basic features of modern life are: First, modern lifestyle is a consumptionism-oriented lifestyle. Consumption has become the main content of modern life. As a result, it is very difficult to distinguish life from consumption. People have changed into consumers. Second, modern lifestyle is a lifestyle of the generalization of (...) commodity logic. Commodity logic has pulled whole society onto the track of the commodity production. People's life is inevitably dominated by the commodity logic, resulting in the prevalence of materialism and money worship. Third, modern lifestyle is a highly homogenized lifestyle,eliminating the possible development of individual personality. The main problems of modern life are: First, lack of conscious reflection of life, People have been lost in a fake sense of happiness. People indulge in a fake sense of happiness created by consumption without any selfconsciousness. Second, lack of correct self-understanding, People have been lost in formal personality. The expressions of formal personality are lack of serious rational thinking. Third, lack of the concern about the transcendent dimension of life, People have been lost in the present dimension of life. People's life has been filled with all kinds of consumergoods and illusions that evoke. Therefore, no room has been left for transcendent issues, such as, the meaning of life. (shrink)

Understanding the neural basis of schizophrenia (SZ) is important for shedding light on the neurobiological mechanisms underlying this mental disorder. Structural and functional alterations in the anterior cingulate cortex (ACC), dorsolateral prefrontal cortex (DLPFC), hippocampus, and medial prefrontal cortex (MPFC) have been implicated in the neurobiology of SZ. However, the effective connectivity among them in SZ remains unclear. The current study investigated how neuronal pathways involving these regions were affected in first-episode SZ using functional magnetic resonance imaging (fMRI). Forty-nine patients (...) with a first-episode of psychosis and diagnosis of SZ—according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision—were studied. Fifty healthy controls (HCs) were included for comparison. All subjects underwent resting state fMRI. We used spectral dynamic causal modeling (DCM) to estimate directed connections among the bilateral ACC, DLPFC, hippocampus, and MPFC. We characterized the differences using Bayesian parameter averaging (BPA) in addition to classical inference (t-test). In addition to common effective connectivity in these two groups, HCs displayed widespread significant connections predominantly involved in ACC not detected in SZ patients, but SZ showed few connections. Based on BPA results, SZ patients exhibited anterior cingulate cortico-prefrontal-hippocampal hyperconnectivity, as well as ACC-related and hippocampal-dorsolateral prefrontal-medial prefrontal hypoconnectivity. In summary, spectral DCM revealed the pattern of effective connectivity involving ACC in patients with first-episode SZ. This study provides a potential link between SZ and dysfunction of ACC, creating an ideal situation to associate mechanisms behind SZ with aberrant connectivity among these cognition and emotion-related regions. (shrink)

The relation between quantum collapse, consciousness and superluminal communication is analyzed. As we know, quantum collapse, if exists, can result in the appearance of quantum nonlocality, and requires the existence of a pre- ferred Lorentz frame. This may permit the realization of quantum superluminal communication (QSC), which will no longer result in the usual causal loop in case of the existence of a preferred Lorentz frame. The possibility of the existence of QSC is further analyzed under the assumption that quantum (...) collapse is a real process. We demonstrate that the combination of quantum collapse and the consciousness of the observer will permit the observer to distinguish nonorthogonal states in principle. This provides a possible way to realize QSC. Some implications of the existence of QSC are briefy discussed. (shrink)

Since rapid economic growth has led to the overuse of natural resources and environmental degradation, increasing attention has been paid to environmental problems. This study aims to explore the relationship between consumers’ perceived value and satisfaction, and energy-saving products purchase intention was investigated using appraisal-emotional response-coping theory. Moreover, this study further investigates these relationships in different consumer groups. In total, 399 questionnaires were collected online and offline, and results though structural equation modeling analysis show that functional, emotional, conditional, and green (...) value have a positive effect on consumer satisfaction and thereby promote the intention to purchase energy-saving products. However, social value is not significant for consumer satisfaction. Perceived value influences consumer satisfaction and varies among different consumers according to the results of multigroup structural equation modeling analysis. These results have practical significance for the design and marketing of energy-saving products. (shrink)

The unique relation between logic and truth is crucial for understanding Fregean conception of logic. Frege has an insight that the nature of logic resides in the “truth“, which he finally locates in the assertoric-force of a sentence. Though Frege admits that assertoric-force is ineffable in ordinary language, he coins in his conceptual notation for such a force a much-disputed sign, i.e., judgment-stroke. In this paper, I will try to demonstrate that judgment-stroke is not adequate for the task its inventor (...) has assigned to it. Accordingly, it is misconceived and inconducive to clarify Frege’s vague insight into the protorelation. The mistake of judgment-stroke for the sign of assertoric-force has its root in Frege’s ignorance of the significant difference between “judgment” and assertion”, which will be elucidated at length in the light of Husserl’s theory of “doxic-modification“. In the end, based on a further elucidation of the activity of assertion, I will advance a tentative interpretation of the vague insight Frege has concerning the protorelation. (shrink)

We define some variations of the Scott rank for countable models and obtain some inequalities involving the ranks. For mono-unary algebras we prove that the game rank of any subtree does not exceed the game rank of the whole model. However, similar questions about linear orders remain unresolved.

本书揭示军旅财富的内涵,它们是:政治头脑、理想信念、牺牲奉献精神、纪律观念、团队精神、勇气与意志、谋略思维、创新能力、军人气质、强健的体魄。.

With the popularization of mobile Internet and smart terminals, mobile reading with diversity and mobility has become a hot issue in the industry and academia. This article comes up with a hypothetical model of mobile reading user acceptance behavior based on the technology acceptance model and unified theory of acceptance and use of technology and conducts an analysis of the reliability and validity of questionnaire data. Based on this, the model fitness is analyzed as well as the path hypotheses testing. (...) We find that user-perceived ease of use greatly influences perceived usefulness, and user attitude and behavioral intention are significantly impacted by perceived usefulness. The impact of social influence on user attitude toward using mobile reading is significant, but the influence of perceived payment is not obvious. The moderating effect of living habit is not obvious because the absolute value of the critical ratio is under 2.58 with a significance level of 0.01. (shrink)

Marx's theory of alienation has some elements of an epistemology, but it is primarily a methodology. This is because alienation and the supersession of alienation are nothing but negation and a negation of the negation, a kind of historical dialectics. In using this methodology to analyze the contradictions between human existence and essence, Marx thoroughly exposed and criticized the callousness of relationships among humanity in capitalist society. On this basis, he considered socialist revolution and socialist production to be the means (...) for eliminating human alienation and for realizing human freedom, and thereby set forth an epistemology. (shrink)

In the Economic and Philosophic Manuscripts of 1844, Marx commented that beauty is "the objectification of human essence.".

As all past philosophies superseded religion, their systems were established on the basis of comprehending a true human essence. As Marx pointed out, after first elaborating various concepts of religion, politics, morality, legal philosophy, and aesthetics, philosophers then kowtowed and became the slaves to those very concepts. Such a condition should be completely altered. From the time when Marx voiced these criticisms and placed "man" at the center of world history, while also pointing out that establishing the position of the (...) subject is proof of human freedom—that is, of human essence—and from the time when Marx emphasized that the real human world, including various social relations, ideological states, and the natural world "possessed by man," is the product of human creativity and a human manifestation formed in history and developed historically, and that man should and can emancipate himself from all that, all previous notions of the human essence became outdated and were no longer worth being seriously debated. From that time on, the philosophy of "man" has transcended the realm of speculative philosophy and gained unprecedented significance both in practice and in reality, and has become an active, initiating force in the modern socialist movement. (shrink)

By focusing on human virtues rather than the general morality of rational beings, Kant’s virtue theory presents systematic arguments from the perspectives of reason and experiential emotion, norms and disposition, spirituality and humanity, etc., which is of great significance to an overall understanding of Kantian ethics, thus clarifying misunderstandings from the past decades.

本书以科技理性与伦理价值的互动关系为逻辑起点,运用历史主义的方法、系统整体论的分析方法、唯物辩证的方法,从社会发展观层面、科技活动层面、人的全面发展层面,论述了对科技理性的伦理价值关怀。.

Since the late 1990s, the dynamics of welfare reform in Taiwan have gradually shifted to tackling new social risks emerging from economic globalization and labor market changes. This article analyzes these structural changes and the relevant institutional features of the labor market. The rise of atypical work has generated wide concern regarding its low wage income and insufficient social protection, triggering debates about which policy measures can effectively tackle the problem of the working poor. Drawing on the quantitative data from (...) a social quality survey conducted by the Social Policy Research Center in National Taiwan University (NTUSPRC) in 2009, our analysis explores the social exclusion differences between regular and atypical workers for their objective and subjective experiences. The objective experiences include current financial situations, negative events, living conditions and political activities of the workers, whereas the subjective experiences refer to their feelings in family position, welfare assessment, discrimination, and autonomy. Our analysis helps explain the effects of work status on the degrees of social exclusion, both in the private and public spheres. The social exclusion experiences of working conditions shed light on social quality in Asia. (shrink)