This paper is about a support information management system for a wind power producer having an energy storage system and participating in a day-ahead electricity market. Energy storage can play not only a leading role in mitigation of the effect of uncertainty faced by a WP producer, but also allow for conversion of wind energy into electric energy to be stored and then released at favourable hours. This storage provides capability for arbitrage, allowing an increase on profit of a WP (...) producer, but must be supported by a convenient problem formulation. The formulation proposed for the support information management system is based on an approach of stochasticity written as a mixed integer linear programming problem. WP and market prices are considered as stochastic processes represented by a set of scenarios. The charging/discharging of the ESS are considered dependent on scenarios of market prices and on scenarios of WP. The effectiveness of the proposed formulation is tested by comparison of case studies using data from the Iberian Electricity Market. The comparison is in favour of the proposed consideration of stochasticity. (shrink)

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

We give in this paper a sufficient condition, cast in semantic terms, for Hallden-completeness in normal modal logics, a modal logic being said to be Hallden-complete (or Ήallden-reasonable') just in case for any disjunctive formula provable in the logic, where the disjuncts have no propositional variables in common, one or other of those disjuncts is provable in the logic.

Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation across basic, translational and clinical research. Contemporaneously, tVNS can be achieved by stimulating either the auricular branch or the cervical bundle of the vagus nerve, referred to as transcutaneous auricular vagus nerve stimulation and transcutaneous cervical VNS, respectively. In order to advance the field in a systematic manner, studies using these technologies need to adequately report sufficient methodological detail to enable comparison of results between (...) studies, replication of studies, as well as enhancing study participant safety. We systematically reviewed the existing tVNS literature to evaluate current reporting practices. Based on this review, and consensus among participating authors, we propose a set of minimal reporting items to guide future tVNS studies. The suggested items address specific technical aspects of the device and stimulation parameters. We also cover general recommendations including inclusion and exclusion criteria for participants, outcome parameters and the detailed reporting of side effects. Furthermore, we review strategies used to identify the optimal stimulation parameters for a given research setting and summarize ongoing developments in animal research with potential implications for the application of tVNS in humans. Finally, we discuss the potential of tVNS in future research as well as the associated challenges across several disciplines in research and clinical practice. (shrink)

Cyclin-dependent kinase 5 has been implicated in Alzheimer's disease pathogenesis. Here, we demonstrate that overexpression of p25, an activator of cdk5, led to increased levels of BACE1 mRNA and protein in vitro and in vivo. A p25/cdk5 responsive region containing multiple sites for signal transducer and activator of transcription was identified in the BACE1 promoter. STAT3 interacts with the BACE1 promoter, and p25-overexpressing mice had elevated levels of pSTAT3 and BACE1, whereas cdk5-deficient mice had reduced levels. Furthermore, mice with a (...) targeted mutation in the STAT3 cdk5 responsive site had lower levels of BACE1. Increased BACE levels in p25 overexpressing mice correlated with enhanced amyloidogenic processing that could be reversed by a cdk5 inhibitor. These data demonstrate a pathway by which p25/cdk5 increases the amyloidogenic processing of APP through STAT3-mediated transcriptional control of BACE1 that could have implications for AD pathogenesis. (shrink)

A.N. Prior once showed that on certain apparently reasonable assumptions, a thesis sometimes associated with the name of Hume to the effect that no set of factual statements can ever entail an evaluative statement, is quite untenable. We assume only that there is at least one statement of each kind, and that the negation of a factual statement is factual — a principle we may call ‘N'. Now consider the disjunction F V E of some factual with some evaluative statement. (...) Since the disjunction is entailed by F, a factual statement, it must, if principle H is correct, be classified as factual. But by N, ∽ F is also factual, and this together with F V E entails E, thus violating H since E was exhypothesi an evaluative statement. (shrink)

A.N. Prior once showed that on certain apparently reasonable assumptions, a thesis sometimes associated with the name of Hume to the effect that no set of factual statements can ever entail an evaluative statement, is quite untenable. We assume only that there is at least one statement of each kind, and that the negation of a factual statement is factual — a principle we may call ‘N'. Now consider the disjunction F V E of some factual with some evaluative statement. (...) Since the disjunction is entailed by F, a factual statement, it must, if principle H is correct, be classified as factual. But by N, ∽ F is also factual, and this together with F V E entails E, thus violating H since E was exhypothesi an evaluative statement. (shrink)

Book reviewed in this article:F.H. Bradley, Collected Works Volumes 1–5.

Spinoza has been appropriated as a philosophical forefather of deep ecology. I identify what I take to be the relevant components of Spinoza ’s metaphysics, which, at face value, appear to be harmonious with deep ecology’s commitments. However, there are central aspects of his moral philosophy which do not appear to be “environmentally friendly,” in particular the sentiments expressed in the Ethics IV35C1 and IV37S1. I describe environmental ethics’ treatment of these passages and then indicate what I take to be (...) a more satisfactory route toward “ecologizing Spinoza.”. (shrink)

What has not yet been imagined in thought is: how to remain together while still being two, how to be and become subjectively two, how to discover a way of coexisting as two beings … a way of living and thinking and loving as two beings without one being reduced to the other? … [t]hanks to the respect that I feel for the other as other, to articulate both attraction and restraint with respect to him. I go out from and (...) return to myself in order to respect his alterity, and this respect for the other becomes respect for myself, my life and my growth. So there is no longer fusion or submission, but the existence of a two which is irreducible to one or to the simple opposition between one (male) and the other (female), a reduction which makes them simply two poles of the one. Luce Irigaray , Democracy Begins Between Two 112-13. (shrink)

This thesis is an investigation of the feasibility of a micropolitical analysis as an evaluative scheme for the analysis of property. The limitations of historical and normative frameworks are discussed. The ontological features of power as understood by Filmer and Locke are compared, and these, to a Foucauldian view of power. The Foucauldian view of power is a better tool of analysis since it reveals and explains more features of "property", including the way that a Lockean conception of property and (...) power, as a point of authority, affects the discourse of property itself. Using a personal and an historical example of the private/public distinction, I establish that these are relational terms built up by various rules of inclusion and exclusion, not upon any prior ground. In particular, I highlight how the production of knowledge functions as one of the conduits in or out of domains; that is, the public and the private are domains of expertise or authority on property. Individuals occupy subjectivities available within the discourse of property which position them, or allow them to position others, as having legitimate or illegitimate relations to property. I show how these subjectivities are the central functional feature of the possibility of normativity. That is to say, whether and how forms of property relations can be evaluated depends on the production of forms of judgment which a subject position makes possible, in form and in content. I ask how present subject positions within the domains of tangible and intangible property work to extend or delimit these domains as moral, political or economic ones. The possibilities of judgment and of freedom from judgment as formal strategies of 4 distinct regimes of power are enumerated, offering an evaluative framework. I ask what, in the domain of property, these 4 regimes offer as formal possibilities for freedom, fairness, and equality. Lastly, I explore Deleuze's concepts of the rhizome and the arborescent with a similar view to reading property as a question of one kind of line rather than another. Finally, I generate from this critical cartography, and bearing in mind the examples of pregnancy and potlatch, a number of responsible strategies one could make from the subject positions identified. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Call for Proposals:The Seventh International Buddhist-Christian Conference, "Hear the Cries of the World"Ruben HabitoThe Society for Buddhist Christian Studies will hold the Seventh International Buddhist-Christian Conference at the Loyola Marymount University campus, Los Angeles, California, 3-8 June 2005. (This conference was earlier posted to take place in August 2004, but was postponed for various reasons.) The overall theme will remain as previously announced: "Hear the Cries of the World: (...) Buddhism and Christianity in Dialogue Toward Global Healing."The program committee welcomes proposals for working groups, scheduled to meet in three successive morning sessions for two hours each, addressing a specific theme or issue, with one or two coordinators and five or more core-group members; full panels, to be presented in one two-hour session, on a specific theme, with a moderator, three to four speakers, and one or two respondents; and individual papers on a specific topic related to an issue or issues in Buddhist-Christian dialogue.Proposals for working groups on themes such as religion and ecology, human rights and social justice, women and religion, toward a global ethic, practice across traditions, Catholic-Buddhist relations, religious responses to violence, religion and globalization, and other relevant themes, are welcomed. Working group proposals should include the title or theme of the working group, a short 200-300 word description of the goal(s) of the working group, and the names and contact information (including address, phone, fax, and e-mail) of the coordinator(s) and at least five other core-group members.Proposals for full panels for a two-hour time slot, addressing specific themes, including issues in doctrine and theory, ritual, religious practice, methodology, and others, are encouraged. Full panel proposals should include the title of the panel, a short 100-200 word description of the theme and intent of the panel, and the names and contact information of the moderator and three or four panel participants.Individual paper proposals for a 30-minute presentation on various themes, including doctrinal, ritual, practical, ethical, and other issues relevant to Buddhist-Christian dialogue are also encouraged. [End Page 245]In addition to the working groups, panel, and individual paper sessions, there will be opportunities for participation in various forms of meditative practice, prayer, and/or ritual in the morning before breakfast and early evening before dinner. These will be led by spiritual leaders and teachers of various Buddhist and Christian traditions.Further, because Los Angeles is known to be one of the most religiously diverse cities in the world, there will be opportunities to visit religious sites in the area and meet with leaders and members of different Buddhist and Christian communities.Proposals preferably should be sent by e-mail to, with a copy to, or by postal mail to Prof. Ruben Habito, Perkins School of Theology, Southern Methodist University, Dallas, TX 75225, USA. The deadline for submission of proposals is 31 January 2005, but early submissions are encouraged.Lodging and meals will be available at the Loyola Marymount University campus in Los Angeles, as well as in hotels nearby. Registration fees and costs for lodging and meals will be announced at a later date. For queries regarding site facilities and registration, please email the conference director, Prof. James Fredericks, at.Copyright © 2004 The University of Hawai'i Press... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Buddhist-Christian Studies 20 (2000) 311-315 [Access article in PDF] Book Review Fire and Water: Basic Issues in Asian Buddhism and Christianity Fire and Water: Basic Issues in Asian Buddhism and Christianity. By Aloysius Pieris, S. J. Maryknoll: Orbis Books, 1996. Aloysius Pieris, Jesuit priest and Buddhist scholar, is well known in theological and interreligious dialogue circles in Asia, and this is the third collection of essays of his to (...) be published in the Faith Meets Faith Series of Orbis Books. The eighteen essays which make up this book, all previously published elsewhere, are conveniently put together in three sections, under the following headings: 1) Women and Religion: Buddhist and Christian Appropriation of Feminist Criticism; 2) issues in Theology, Religion and Society; and 3) questions of Spirituality and Human Liberation. To merely summarize the content of the essays and offer a third-party critique would do injustice to the book, and could even mislead one who peruses such a summary into thinking one thereby "knows" what the book or Pieris is about. Such a hasty conclusion would deprive a would-be reader of the powerful experience that awaits in wrestling with Pieris through each essay of this volume. Judith Berling puts it well in her blurb at the back, pointing out that the author "uses poetry, evocative symbolism, and humor to offer a theological call to action in a voice that is liberationist, Asian, and feminist." Indeed, this volume invites one to a way of seeing that can also transform one's way of being in this world marked by increasing violence, poverty, and a systemic kind of oppression dehumanizing to both the perpetrators as well as the victims.The title of the present volume, Fire and Water, alludes to a dynamic dipolarity, masterfully sketched for the reader by Paul Knitter in his foreword, which underlies the author's vision of reality and vivifies much of his writing. The masculine and the feminine, the (Buddhist) gnostic and the (Christian) agapeic, the metacosmic (transcendent) [End Page 311] and the cosmic (immanent), the prophetic and the mystical, are different ways of naming this dipolarity. The way to ultimate liberation is in the effective embrace of both poles in complementarity and mutual interplay, whereas taking one pole in preference over the other results in a warped vision or mode of being, in imbalance, or even in abuse.In this review I would like to simply echo some key themes that will jump at one perusing the essays, reiterating that the very act of reading them can of itself be a transformative experience for an open-minded, open-hearted, and open-handed reader.The thrust of the six essays comprising the first section can perhaps be summed up in the thesis as formulated by the author himself: "Religion cannot survive in the future without appropriating the feminist critique, just as feminism cannot achieve its liberative goal without the aid of a religion so critiqued" (p. 62). Behind this statement is Pieris' emphatically critical stance, on the one hand, against all forms of patriarchal religion, whether Christian, Buddhist, Hindu, or other, which has justified, lent a hand in, or continued to perpetrate the physical, psychological, and especially religious abuse of women, and on the other hand, against secularist (or anti-religious) kinds of feminist theory that take off on what he enumerates as "five false starts" (pp. 50-51), which only result in unnecessary dichotomies that truncate the understanding of the goal of liberation, and consequently of the human as such.Pieris offers a vision of liberation centered on what he terms the humanum. This refers to the point of ultimate perfection to which the human, that is, "whatever pertains to men and women as self-conscious, other-oriented, and dreaming components of the cosmos," has the capacity to carry the cosmos. In this context, the human is no other than "this self-transcendent capacity immanent in the cosmos, this power to unfold within itself the Other, which is ever present from the first moment of evolution." To be human is inherently to be endowed... (shrink)

Aims and background: The present work assessed the impact of two decrees on ethics committees in Italy, aimed at bringing the national laws on the conduct of clinical trials into line with the rest of the EC, and regulating and facilitating not-for-profit research.Material and methods: Prospectively collected data from an Italian multicentre study were examined with respect to the ethics review process. Administrative and time elements of the review process were audited. Main outcome measures were time between the application submission (...) and the ethics committee definitive opinion, type and number of application submission forms, number of ethics committees that refused fee exemption, and time between the ethics committee approval and the administrative authorisation.Results: A total of 134 local research ethics committees were approached. Application submission procedures and application forms varied greatly; paper submission was mandatory. The median time from submission to approval was 72 days. Only two LRECs refused the fee exemption. The median time from LREC approval to administrative agreement was 50 days and only 9.6% of local authorities came to a verbal agreement with the sponsor.Conclusions: Italian LRECs are still not sufficiently efficient in complying with the Directive 2001/20/EC requirement . Better coordination of LRECs work is needed although the optimal level of coordination between them is still not known. In the meantime, national guidelines are needed concerning the application of Directive 2001/20/EC. The behaviour of Italian LRECs towards not-for-profit research was excellent although only the fee exemption was requested. (shrink)