Die Welt ist alles, was wir in unseren naturwissenschaftlichen Theorien beschreiben können – so eine weit verbreitete Überzeugung, die seit den Tagen des Positivismus unser Weltbild bestimmt. Aber reicht das tatsächlich schon aus? Wer sich am Ideal der wissenschaftlichen Erkenntnis orientiert, neigt dazu, viele nicht-begriffliche Erfahrungsformen zu unterschlagen, die uns aus dem Alltag vertraut sind: Symbolsysteme wie Musik, Literatur oder Bilder, Instanzen der unmittelbaren Erfahrung wie Anschauung, Wahrnehmung oder Gefühl und den Bereich des praktischen Könnens. In der Regel sind wir (...) nicht in der Lage, den Gehalt dieser Phänomene vollständig begrifflich wiederzugeben. Dennoch ist das weite Feld des Nichtbegrifflichen eine unverzichtbare Voraussetzung unserer Sätze und Gedanken: Ohne Kunst, Wahrnehmung und Handeln gibt es kein Denken, keine Wissenschaft, keine Philosophie. Der Band geht der Vielfalt des Nicht-Begrifflichen in ästhetischen, symboltheoretischen und semantischen Untersuchungen nach. Aus ihnen ergibt sich ein umfassender systematischer Überblick über eines der spannendsten und offensten Problemfelder der aktuellen philosophischen Debatte. Mit Beiträgen von: Andreas Bartels, Uwe Baumann, Volker Beeh, Gottfried Boehm, Olaf Breidbach, Joachim Bromand, Gottfried Gabriel, Markus Gabriel, Ernest Wolf Gazo, Annemarie Gethmann-Siefert, Jürgen Goldstein, Jens Halfwassen, Thomas Sören Hoffmann, Wolfgang Harms, Jochen Hörisch, Peter Janich, Guilherme F. R. Kisteumacher, Jakub Kloc-Konkolowicz, Imi Knoebel, Theo Kobusch, Klaus-M. Kodalle, Sibylle Krämer, Guido Kreis, Wolfgang Kubin, Sönke Lorenz, Antonio Cota Marçal, Aliasghar Mosleh, Theodoros Penolidis, Dominik Perler, Hans-Joachim Pieper, Andrzej Przylebski, Birgit Sandkaulen, Matthias Schmoeckel, Oswald Schwemmer, Josef Simon, Pirmin Stekeler-Weithofer, Dieter Teichert, Kai Vogeley, Gottfried Willems und Gereon Wolters. (shrink)

The Handbook of Modal Logic contains 20 articles, which collectively introduce contemporary modal logic, survey current research, and indicate the way in which the field is developing. The articles survey the field from a wide variety of perspectives: the underling theory is explored in depth, modern computational approaches are treated, and six major applications areas of modal logic (in Mathematics, Computer Science, Artificial Intelligence, Linguistics, Game Theory, and Philosophy) are surveyed. The book contains both well-written expository articles, suitable for beginners (...) approaching the subject for the first time, and advanced articles, which will help those already familiar with the field to deepen their expertise. Please visit: http://people.uleth.ca/~woods/RedSeriesPromo_WP/PubSLPR.html - Compact modal logic reference - Computational approaches fully discussed - Contemporary applications of modal logic covered in depth. (shrink)

Revised and reprinted in Handbook of Philosophical Logic, volume 10, Dov Gabbay and Frans Guenthner (eds.), Dordrecht: Kluwer, (2003). -- Two sorts of property theory are distinguished, those dealing with intensional contexts property abstracts (infinitive and gerundive phrases) and proposition abstracts (‘that’-clauses) and those dealing with predication (or instantiation) relations. The first is deemed to be epistemologically more primary, for “the argument from intensional logic” is perhaps the best argument for the existence of properties. This argument is presented in the (...) course of discussing generality, quantifying-in, learnability, referential semantics, nominalism, conceptualism, realism, type-freedom, the first-order/higher-order controversy, names, indexicals, descriptions, Mates’ puzzle, and the paradox of analysis. Two first-order intensional logics are then formulated. Finally, fixed-point type-free theories of predication are discussed, especially their relation to the question whether properties may be identified with propositional functions. (shrink)

Revised and reprinted; originally in Dov Gabbay & Franz Guenthner (eds.), Handbook of Philosophical Logic, Volume IV. Kluwer 133-251. -- Two sorts of property theory are distinguished, those dealing with intensional contexts property abstracts (infinitive and gerundive phrases) and proposition abstracts (‘that’-clauses) and those dealing with predication (or instantiation) relations. The first is deemed to be epistemologically more primary, for “the argument from intensional logic” is perhaps the best argument for the existence of properties. This argument is presented in the (...) course of discussing generality, quantifying-in, learnability, referential semantics, nominalism, conceptualism, realism, type-freedom, the first-order/higher-order controversy, names, indexicals, descriptions, Mates’ puzzle, and the paradox of analysis. Two first-order intensional logics are then formulated. Finally, fixed-point type-free theories of predication are discussed, especially their relation to the question whether properties may be identified with propositional functions. (shrink)

Our concern is the completeness problem for spi-logics, that is, sets of implications between strictly positive formulas built from propositional variables, conjunction and modal diamond operators. Originated in logic, algebra and computer science, spi-logics have two natural semantics: meet-semilattices with monotone operators providing Birkhoff-style calculi and first-order relational structures (aka Kripke frames) often used as the intended structures in applications. Here we lay foundations for a completeness theory that aims to answer the question whether the two semantics define the same (...) consequence relations for a given spi-logic. (shrink)

During the COVID-19 pandemic, students were facing great challenges. Learning was shifted from the classroom to the home of the students. This implied that students had to complete their tasks in a more autonomous way than during regular lessons. As students’ ability to handle such challenges might depend on certain cognitive and motivational prerequisites as well as individual learning conditions, the present study investigates students’ cognitive competencies as well as affective-motivational factors as possible predictors of coping with this new learning (...) situation at home. The study uses data of Starting Cohort 2 of the German National Educational Panel Study. Data of two measurement points are analyzed: Predictors were assessed at the earlier time point, when students mostly attended seventh grade of a secondary school. They completed competence tests in reading as well as mathematics and rated affective-motivational aspects in terms of willingness to exert effort, learning enjoyment, and intrinsic motivation. One and a half years later − during the COVID-19 pandemic and the first period of school closures − the second measurement point took place. Students’ parents rated the situation of learning at home with respect to students’ coping with the new situation and parents’ difficulties to motivate them. Regression analyses controlling for school track, students’ gender, and parents’ educational level and parental stress revealed that students’ reading competencies and their willingness to exert effort were significant predictors of their coping with the new learning situation at home. Moreover, parents reported that boys were more difficult to motivate to learn during this time as compared to girls. Other predictors turned out to be non-significant when entered simultaneously in the regression analyses. The results point to the importance of children’s prerequisites for autonomous learning situations without structuring elements by teachers within the school context. (shrink)

A new argument in favour of free will is given. It shows that our will is free in a comprehensive sense. The argument is developed in the context of a decision situation, which is paradigmatic for the discussion of free will and human action. German Eine schlüssige Begründung für die Willensfreiheit des Menschen wird vorgestellt. Sie zeigt, dass wir in einem sehr weit reichenden Sinne frei sind. Das Argument wird im Kontext einer Entscheidungssituation präsentiert, die für die Diskussion um Handlungs- (...) und Willensfreiheit paradigmatischen Charakter hat. (shrink)

The aim of this contribution is to provide a rather general answer to Hume’s problem. To this end, induction is treated within a straightforward formal paradigm, i.e., several connected levels of abstraction. Within this setting, many concrete models are discussed. On the one hand, models from mathematics, statistics and information science demonstrate how induction might succeed. On the other hand, standard examples from philosophy highlight fundamental difficulties. Thus it transpires that the difference between unbounded and bounded inductive steps is crucial: (...) while unbounded leaps of faith are never justified, there may well be reasonable bounded inductive steps. In this endeavour, the twin concepts of information and probability prove to be indispensable, pinning down the crucial arguments, and, at times, reducing them to calculations. Essentially, a precise study of boundedness settles Goodman’s challenge. Hume’s more profound claim of seemingly inevitable circularity is answered by obviously non-circular hierarchical structures. (shrink)

This book introduces the notions and methods of formal logic from a computer science standpoint, covering propositional logic, predicate logic, and foundations ...

The central focus of this book is the concept of higher education reform in the light of an international and global comparative perspective. After decades of far-reaching reform, higher education around the world has profoundly changed and now has to face the challenges of the present. This volume takes a close look at these changes, the drivers of change, their effects and possible future scenarios. In their contributions the authors discuss a variety of basic concepts: learning and teaching in higher (...) education; financing and quality assurance; governance change; massification vs. equity and equality; internationalization and mobility, the implementation of lifelong structures in higher education. (shrink)

Genetic testing has familial implications. Counsellors find themselves in (moral) conflict between medical confidentiality (towards the patient) and a potential right or even duty to warn at-risk relatives. Legal regulations vary between countries. English literature about German law is scarce. We reviewed the literature of relevant legal cases, focussing on German law, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. This article aims to familiarise counsellors with their responsibilities, compare the situation between countries and point out (...) legally unresolved areas.According to the German Genetic Diagnostics Act (Gendiagnostikgesetz) in case of an ‘avoidable or treatable’ genetic disorder, geneticists ought to confine themselves to the obligated advice to the patient. Whether a breach of the duty of confidentiality can be justified in exceptional cases by ‘necessity as justification’ for actively informing relatives at risk remains legally unclear. In case of a ‘neither avoidable nor treatable’ genetic disease, geneticists should also refrain from actively informing relatives as the justifiable state of emergency does not permit to break the duty of confidentiality. (shrink)

Zusammenfassung. Gegenwärtige Fortschritte in den pharmakologischen Wissenschaften erlauben einen ersten Ausblick auf eine individuelle, genotyp-basierende Arzneimitteltherapie, durch die sich die Effektivität der Medikamentenbenutzung weiter verbessern ließe. Die genotypische Erfassung von genetischen Polymorphismen, die bei Medikamentenreaktionen beteiligt sind, verspricht die Arzneimitteltherapie grundlegend zu optimieren, wenn damit Patienten identifiziert werden, für die ein Medikament entweder nutzbringend und sicher angewandt oder aber aufgrund zu erwartender Nebenwirkungen nicht eingesetzt werden sollte. Die neuen pharmakogenomischen Behandlungsstrategien werfen komplexe ethische Fragestellungen auf, da durch ein genetisches Screening (...) für Arzneimittelzwecke asymptomatische Patienten mit erhöhtem Risiko für eine insgesamt schlechtere Prognose identifiziert werden könnten. Die Pharmakogenomik beeinflusst damit das Beziehungsverhältnis zwischen behandelnden Arzt und Patienten, das traditionell auf Diskretion, Vertraulichkeit und dem unbedingten Vorsatz, heilen und keinesfalls schaden zu wollen, beruht. Der vorliegende Aufsatz diskutiert einige ethische Aspekte im Bedeutungswandel der Arzt-Patienten-Beziehung, der durch diesen neuartigen pharmakogenomischen Behandlungsansatz ausgelöst wird. (shrink)

Definition of the problem: Recent progress in the pharmacological sciences provides a first glimpse of the development of an individual, genotype-based drug therapy in order to improve the efficiency of drug utilization. Genotyping of genetic polymorphisms in genes involved in drug response promises to optimize drug therapy fundamentally by identifying patients for whom a pharmaceutical agent may be effective and safe or contraindicated because of expected adverse drug reactions. Arguments: The new pharmacogenomic treatment strategies raise complex bioethical issues, because genetic (...) screening for drug therapy may identify asymptomatic patients who are at risk for a particular adverse outcome. Thus, pharmacogenomics will affect the relationship between the treating physician and the patient which is traditionally based on privacy, confidentiality, beneficience and non-maleficience. Conclusion: In the article presented some ethical aspects of these new pharmacogenomic approaches concerning the physician-patient relationship are discussed. (shrink)

Human freedom and the autonomy of art : Adorno as a reader of Kant -- The ephemeral and the absolute : provisional notes to Adorno's aesthetic theory -- Aesthetic violence : the concept of the ugly in Adorno's aesthetic theory -- Reality, realism, and representation -- A precarious balance : Adorno and German classicism.

Apart from positive priming effects, masked prime stimuli can impair responses to a subsequent target stimulus which shares response-critical features in contrast to a target assigned to the opposite response. This counterintuitive phenomenon is called inverse priming . Here we examine the generality of this phenomenon beyond priming of motor responses. We used a non-motor cue-priming paradigm to study the underlying mechanism of inverse priming for relevant features masks which include task-relevant stimulus features and for irrelevant masks which omit task-relevant (...) features. We found inverse cue-priming effects with both types of masks. With task-irrelevant masks inverse cue-priming was emphasized in those participants being unable to perceive the prime. The existence of inverse non-motor priming under conditions where simple perceptual interactions between the stimuli are ruled out as the source of inverse priming is at odds with the view that inverse priming reflects motor inhibition. Alternatives are discussed. (shrink)

Gottlob Frege ist der Begründer der modernen Logik und einer der Väter der analytischen Philosophie. Bertrand Russell, Rudolf Carnap und Ludwig Wittgenstein haben seine Ideen aufgegriffen und weiterentwickelt. Dieses Buch liefert eine Bestandsaufnahme zu Werk und Wirkung Freges. Gewürdigt werden seine Leistungen als Logiker, Mathematiker, Sprachphilosoph und Methodologe. Im Ausgang von historischen Untersuchungen zum ursprünglichen 'kontinentalen' Ort des Frege schen Denkens wird die internationale Rezeption und das systematische Gewicht der Philosophie Frege s entfaltet. Mit Beiträgen von: Michael Astroh, Detlef Gronau, (...) Wolfgang Kienzler, Lothar Kreiser, Volker Peckhaus, Eva Picardi, Erich H. Reck, Marco Ruffino, Christiane Schildknecht, Joachim Schulte, Rainer Stuhlmann-Laeisz, Christian Thiel, Kai F. Wehmeier. (shrink)

In [STU 00, KUT 03] we introduced a family of ‘modal' languages intended for talking about distances. These languages are interpreted in ‘distance spaces' which satisfy some of the standard axioms of metric spaces. Among other things, we singled out decidable logics of distance spaces and proved expressive completeness results relating classical and modal languages. The aim of this paper is to axiomatize the modal fragments of the semantically defined distance logics of [KUT 03] and give a new proof of (...) their decidability. (shrink)

At first glance the three eukaryotic protein translocation machineries – the ER‐associated degradation (ERAD) transport apparatus of the endoplasmic reticulum, the peroxisomal importomer and SELMA, the pre‐protein translocator of complex plastids – appear quite different. However, mechanistic comparisons and phylogenetic analyses presented here suggest that all three translocation machineries share a common ancestral origin, which highlights the recycling of pre‐existing components as an effective evolutionary driving force.Editor's suggested further reading in BioEssays ERAD ubiquitin ligases Abstract.

Beta‐oxidation of fatty acids and detoxification of reactive oxygen species are generally accepted as being fundamental functions of peroxisomes. Additionally, these pathways might have been the driving force favoring the selection of this compartment during eukaryotic evolution. Here we performed phylogenetic analyses of enzymes involved in beta‐oxidation of fatty acids in Bacteria, Eukaryota, and Archaea. These imply an alpha‐proteobacterial origin for three out of four enzymes. By integrating the enzymes' history into the contrasting models on the origin of eukaryotic cells, (...) we conclude that peroxisomes most likely evolved non‐symbiotically and subsequent to the acquisition of mitochondria in an archaeal host cell. (shrink)

Quantum physics, unlike classical physics, suggests a non-physicalistic metaphysics. Whereas physicalism implies a reductive position in the philosophy of mind, quantum physics is compatible with non-reductionism, and actually seems to support it. The essays in this book explore, from various points of view, the possibilities of basing a non-reductive philosophy of mind on quantum physics."--Back cover.