Suls provides a useful review of research interested in the contribution of chronic negative emotions to coronary heart disease. Despite widespread support for a link between negative emotions and the etiology of disease, it is largely unknown if discrete negative emotions, particularly anger, sadness, and anxiety contribute to the development of physical disease in different ways. In this comment, we argue that answering this question will require a more comprehensive analysis of the unique characteristics of discrete emotions as well as (...) conceptually refined assumptions about how discrete emotions develop and change across the adult lifespan. (shrink)

ABSTRACTThis study investigated age differences in empathic accuracy, the ability to correctly perceive others’ emotions, in a sample of 151 boys and men from three age groups: adolescents, young adults, and middle-aged adults. All participants viewed nine newly developed film clips, each depicting a boy or a man reliving one of three emotions, while talking about an autobiographical memory. Adolescents and middle-aged men were less accurate than young men, and these age differences were associated with parallel age differences in fluid-mechanical (...) abilities. In addition, age differences in vocabulary, one indicator of crystallized-pragmatic intelligence, were associated with age differences in empathic accuracy in adolescent and young, but not middle-aged, men. Within the limitations of cross-sectional data, this study provides evidence for the idea that empathic accuracy is an effortful t... (shrink)

A revised and enlarged version of Biologen unter Hitler, translated by Thomas Dunlap.

This essay examines dominant notions of reproductive identity in feminist bioethics from a queer-crip perspective by considering the “reproductive situation” in Germany of people who are classified as disabled and people who are classified as queer. I analyze the ways in which such people are excluded from the understandings of reproductive identity that figure prominently in German feminist bioethics, and argue that feminist bioethics in Germany, which has become a well-established part of important bioethical institutions, reflects many, if not most, (...) of the neo-eugenic developments that characterize more recognizably mainstream bioethics. I also show that feminist bioethics constitutes the reproductive subject as nondisabled, intelligibly gendered, and heterosexual. (shrink)

Eukaryotic genomes are packaged into a nucleoprotein complex known as chromatin. The term was introduced in 1879 by German cytologist Walther Flemming. While observing the processes of mitosis in a light microscope, Flemming coined the term to describe the easily stainable threads in the nucleus. He predicted that it would not have a long life: “The word chromatin may serve until its chemical nature is known, and meanwhile stands for that substance in the cell nucleus which is readily stained”. However, (...) Flemming’s prediction did not come true. Although the chemical nature of chromatin—a complex of nucleic acid and proteins—was already elucidated at the end of the 19th century, the.. (shrink)

This paper discusses the extent to which governmentality provides a critical visibility of the economy beyond its liberal imaginary. It argues that Foucault’s conceptual and historical understanding of liberal governmentality has two traits that encumber a de-centering of the economy from a Foucauldian perspective. The first obstacle results from a persistent asymmetry of the concept of governmentality as it remains solely geared towards replacing the monolithic account of the state. Governmentality is therefore in danger of rendering the economic invisible instead (...) of advancing an analytics of power appropriate to the specificity of this field. The second impediment relates to how Foucault reads the invisibility of the economy asserted in liberal discourse. While Foucault emphasizes how the “invisible hand” imparts a critical limitation towards the sovereign hubris of total sight, the paper unearths a more complex politics of truth tied to the invisible economy. Drawing on selected historical material, the papers shows that the liberal invisibility of the economy rather functions as a prohibitive barrier towards developing novel and critical visibilities of the economy. A Foucauldian perspective on economy, the paper concludes, benefits from piercing through this double invisibility of the economy. (shrink)

Mindfulness has emerged as a potential motivator for sustainable lifestyles, yet few studies provide insight into the relationship between mindfulness practice levels and individual engagement in pro-environmental behaviors. We also lack information about the significance of meditators’ behavioral differences in terms of their measurable environmental impact and the motivational processes underlying these differences in pro-environmental performance. We classified 300 individuals in three groups with varying meditation experience and compared their pro-environmental motivations and levels of animal protein consumption. Exceeding prior attempts (...) to compare high-impact behaviors of mindfulness practitioners and non-practitioners, we created the most detailed classification of practice engagement by assessing frequency, experience and type of meditation practice. This nuanced view on mindfulness practice reveals that advanced meditators, who reported high levels of connectedness with nature, subjective happiness and dispositional mindfulness showed significantly more concern for the environment. They also demonstrated the lowest levels of greenhouse gas emissions, land occupation and water use related to their animal-protein consumption. This study is the first to follow a self-determination theory perspective to deepen our understanding of the motivational differences between meditator groups. We revealed that advanced meditators reported significantly more integrated motivation toward the environment than non-meditators. We also provided preliminary evidence for a new theoretical framework suggesting that experiential strategies such as mindfulness practices could strengthen the relational pathway of pro-environmental behaviors. Using sequential mediation analysis, we confirmed that the negative effect of mindful compassion practice on greenhouse gas emissions from animal-protein consumption is partially mediated by CWN and integrated motivation toward the environment. While our study does not support assumptions of causality, it shows that much can be learned by studying the motivations of advanced meditators for maintaining high levels of pro-environmental behavior. (shrink)

A recent cover of the German news magazine Der Spiegel announced: “Victory over Genes. Smarter, healthier, happier: How we can outwit our genome” (2010). The magazine’s article, instead, emphasizes the importance of epigenetics. According to Florian Maderspacher (2010), who reprinted the cover in his editorial in Current Biology, the relief or “schadenfreude” about the apparent victory over genes—which the cover, the article, and commentaries to it reveal—is, in part, a German phenomenon. It echoes “a latent anti-scientific attitude in parts of (...) the German public,” which for historic reasons is particularly strong with regard to genetics: “After all, the idea that people’s properties—good or bad—are determined by .. (shrink)

This article argues that Foucault’s account of the intersection between population, liberal economy, and biopolitics needs to be reconstructed in light of Malthus’ Essay on the Principle of Population. Taking Malthus into account brings to the fore how deeply the question of population is tied to a colonial hierarchy that differentiates between dangerous ‘savage’ and economic ‘civilized’ life. ‘Savage life’ is depicted as a catastrophic form of life, which uses resources in a non-economic way due to its forgetfulness of the (...) future. The article shows how this notion of ‘savage life’ broadens the concept of liberal economic governmentality. Most importantly, it highlights the role of passions and futurity for liberal governmentality. As the discussion of Malthus’ texts demonstrates, the passions of hope and fear assume a crucial role for engendering futurity in the economic subject. As will be shown, while the more ‘savage life’ is considered to be made governable through fear, the more civilized life is supposed to be allured by hope. The article points out the implication of this analysis for Foucault’s notion of biopolitics in relation to liberal economy. (shrink)

Dissatisfied with the descriptive and speculative methods of evolutionary biology of his time, the physiologist Jacques Loeb , best known for his “engineering” approach to biology, reflected on the possibilities of artificially creating life in the laboratory. With the objective of experimentally tackling one of the crucial questions of organic evolution, i.e., the origin of life from inanimate matter, he rejected claims made by contemporary scientists of having produced artificial life through osmotic growth processes in inorganic salt solutions. According to (...) Loeb, the answer to the question of whether or not life could be created artificially had to come from macro-molecular chemistry, in particular from the research on the recently discovered DNA. He was convinced that a prerequisite for making living matter from inanimate substances was the chemical synthesis of nuclear material capable of self-replication. Moreover, Loeb, experimentally refuting some vitalistic explanations as well as colloidal chemists’ far-reaching claims that biologically relevant macromolecules follow colloidal rather than chemical laws, pioneered research on the physical and chemical explanations of biological phenomena. (shrink)

OUTSTANDING PAPER AWARD, Division of the History of Chemistry, American Chemical Society.

In Goethe's Faust, the poet refers to alchemists' widespread ideas on artificial creation of life in the laboratory. In Faust, such an attempt was not successful: the little man,Homunculus, created by the scholar Wagner through crystallization, was a pure spirit; his form and light disappeared in an attempt to become real life. According to Goethe, life was obviously not a crystal, and he pointed to decisive differences between crystals and organic beings, the latter for example elaborating their food into clear-cut (...) organs and unable to be reconstituted from their ingredients, once destroyed. Thus Goethe's "sensitivity to the 'Gestalt' of the entire complicated organism and his general philosophical attitude .. (shrink)

Le Code civil français, premier code libéral et bourgeois d’Europe, passe, en raison de sa clarté systématique et de sa langue, pour un modèle de législation moderne. En outre, il eut une influence durable parce qu’il est resté en vigueur dans de nombreux pays d’Europe après la fin des conquêtes napoléoniennes. Pourtant, en comparaison avec d’autres codifications européennes et avec le droit coutumier de son temps, le Code français se caractérise, dans le droit conjugal et familial, par des règles particulièrement (...) rigides consolidant la domination masculine. L’article propose une analyse comparée de certains aspects du droit civil qui ont eu et ont encore un impact considérable sur la vie des femmes et sur l’histoire des mouvements féministes. Il se demande pourquoi les Françaises, qui se sont fait entendre plus tôt que d’autres dans leur lutte pour les droits des femmes qu’elles revendiquaient comme des droits humains, ont paradoxalement obtenu la reconnaissance de leur égale citoyenneté relativement tard (en 1944 seulement) par rapport aux autres pays européens. (shrink)

Raum und Zeit sind Grundprobleme der abendlandischen Philosophietradition. Beide sind vielfach als zusammengehorig betrachtet worden, und beide sind als messbare Dimensionen Teil einer Ordnung, die uns in unserem Wahrnehmen und in unserem Handeln Orientierung und Sicherheit gibt. So verlassen wir uns bei jeder Verabredung darauf, dass der Treffpunkt und der Zeitpunkt der Verabredung eindeutig sind. Doch gibt es neben der linearen Zeit und dem metrischen Raum auch andere Weisen, Raum und Zeit zu erleben. Wenn man die Welt als offenes Zusammenspiel (...) von Dingen und Geschehnissen und Beziehungen versteht, so verlangt dies auch eine andere Auffassung von Raum und Zeit: Wir weilen und verweilen in Raumen, die uns umfangen und beherbergen. Wir empfinden kurze oder lange Weile. Und wir erfahren Weite, etwa in ihrem Gegenspiel zu Enge und Bedrangnis, wir stehen vor einer weiten Landschaft oder am weiten Meer - unser Herz wird weit. Indem wir uns einer Weile anvertrauen oder eine Weite in uns aufnehmen oder uns ihr uberlassen, behandeln wir das uns Begegnende nicht als Objekt unseres Tuns und Erkennens, sondern realisieren, dass wir in die uns umgebende Welt mit ihren je unterschiedlichen Weilen und Weiten je schon eingebettet sind. (shrink)

In contrast to anti-Jewish campaigns at German universities in the 19th century, which met with opposition from liberal scholars, among them prominent chemists, there was no public reaction to the dismissals in 1933. Germany had been an international leader in chemistry until the 1930s. Due to a high proportion of Jewish physicists, chemistry was strongly affected by the expulsion of scientists. Organic and inorganic chemistry were least affected, while biochemistry suffered most. Polymer chemistry and quantum chemistry, of minor importance among (...) the majority of academic chemists was further weakened by the expulsion of renowned scientists. However, a look at the research carried out in Nazi Germany shows that no field of research "emigrated" as such, except research into molecular beams. The reception of emigré chemists differed with respect to their field of research and the degree of competition in the host countries. Thus biochemists and physical chemists were accepted at American universities, whereas organic chemists were not. In contrast, they received high positions in Turkey, Palestine/Israel, and Egypt. After WWII, few emigrés were asked to come back. The delay of the resumption of international contacts by German chemists contributed to the delay in rebuilding in particular German biochemistry, the physical chemistry of polymers, and physical organic chemistry. (shrink)

Inheritance and variation were a major focus of Charles Darwin’s studies. Small inherited variations were at the core of his theory of organic evolution by means of natural selection. He put forward a developmental theory of heredity (pangenesis) based on the assumption of the existence of material hereditary particles. However, unlike his proposition of natural selection as a new mechanism for evolutionary change, Darwin’s highly speculative and contradictory hypotheses on heredity were unfruitful for further research. They attempted to explain many (...) complex biological phenomena at the same time, disregarded the then modern developments in cell theory, and were, moreover, faithful to the widespread conceptions of blending and so-called Lamarckian inheritance. In contrast, Mendel’s approaches, despite the fact that features of his ideas were later not found to be tenable, proved successful as the basis for the development of modern genetics. Mendel took the study of the transmission of traits and its causes (genetics) out of natural history; by reducing complexity to simple particulate models, he transformed it into a scientific field of research. His scientific approach and concept of discrete elements (which later gave rise to the notion of discrete genes) also contributed crucially to the explanation of the existence of stable variations as the basis for natural selection. (shrink)

In this second decade of the 21st century, we find the pervasive influence of synthetic biology everywhere, not only in research laboratories, but also in the discourses of politicians and ethicists. Despite its ubiquity, the precise meaning of the notions of "synthetic biology" and "synthetic life," as well as their history, potential, and risks, remain obscure not only to the layperson, but also to most biologists.The aim of this special issue is twofold. First, it is intended to help the reader (...) better appreciate what synthetic biology is all about and what are its roots. Second, once the overall picture has been expounded and made clearer, the questions of whether research in synthetic biology raises new and .. (shrink)

Problems, Phenomena, Explanatory Approaches Who is a German-Jewish Scientist? 1. The Einstein case and its paradoxes On 14 March 1929, Albert Einstein's ...

Eric Davidson, a passionate molecular developmental biologist and intellectual, believed that conceptual advances in the sciences should be based on knowledge of conceptual history. Convinced of the superiority of a causal-analytical approach over other methods, he succeeded in successfully applying this approach to the complex feature of organismal development by introducing the far-reaching concept of developmental Gene Regulatory Networks. This essay reviews Davidson’s philosophy, his support for the history of science, and some aspects of his scientific personality.

The concepts of hierarchical organization, genetic determinism and biological specificity have played a crucial role in biology as a modern experimental science since its beginnings in the nineteenth century. The idea of genetic information and genetic determination was at the basis of molecular biology that developed in the 1940s with macromolecules, viruses and prokaryotes as major objects of research often labelled “reductionist”. However, the concepts have been marginalized or rejected in some of the research that in the late 1960s began (...) to focus additionally on the molecularization of complex biological structures and functions using systems approaches. This paper challenges the view that ‘molecular reductionism’ has been successfully replaced by holism and a focus on the collective behaviour of cellular entities. It argues instead that there are more fertile replacements for molecular ‘reductionism’, in which genomics, embryology, biochemistry, and computer science intertwine and result in research that is as exact and causally predictive as earlier molecular biology. (shrink)

: In contrast to anti-Jewish campaigns at German universities in the 19th century, which met with opposition from liberal scholars, among them prominent chemists, there was no public reaction to the dismissals in 1933. Germany had been an international leader in (bio-)chemistry until the 1930s. Due to a high proportion of Jewish physicists, (bio-)chemistry was strongly affected by the expulsion of scientists. Organic and inorganic chemistry were least affected, while biochemistry suffered most. Polymer chemistry and quantum chemistry, of minor importance (...) among the majority of academic chemists (despite pioneering work by German physicists) was further weakened by the expulsion of renowned scientists. However, a look at the research carried out in Nazi Germany shows that no field of research "emigrated" as such, except research into molecular beams. The reception of emigré (bio-)chemists differed with respect to their field of research and the degree of competition in the host countries. Thus biochemists and physical chemists were accepted at American universities, whereas organic chemists were not. In contrast, they received high positions in Turkey, Palestine/Israel, and Egypt. After WWII, few emigrés were asked to come back. The delay of the resumption of international contacts by German (bio-)chemists contributed to the delay in rebuilding in particular German biochemistry, the physical chemistry of polymers, and physical organic chemistry. (shrink)

The paper presents the donkey's bray in Robert Bresson's film (F 1966) that disturbs the montage insistently as an open sound object and puts it in the context of bioacoustics. The donkey's hee-haw diversifies noise in such a way that the borderline between object and creature becomes permeable. Bresson's passion proves to be an experiment to perceive the acoustic channels of communication as transformers of animals, spaces and that kind of transmission that researchers informed by cybernetics call »language«.

Methods and equations for analysing the kinetics of enzyme-catalysed reactions were developed at the beginning of the 20th century in two centres in particular; in Paris, by Victor Henri, and, in Berlin, by Leonor Michaelis and Maud Menten. Henri made a detailed analysis of the work in this area that had preceded him, and arrived at a correct equation for the initial rate of reaction. However, his approach was open to the important objection that he took no account of the (...) hydrogen-ion concentration (a subject largely undeveloped in his time). In addition, although he wrote down an expression for the initial rate of reaction and described the hyperbolic form of its dependence on the substrate concentration, he did not appreciate the great advantages that would come from analysis in terms of initial rates rather than time courses. Michaelis and Menten not only placed Henri's analysis on a firm experimental foundation, but also defined the experimental protocol that remains standard today. Here, we review this development, and discuss other scientific contributions of these individuals. The three parts have different authors, as indicated, and do not necessarily agree on all details, in particular about the relative importance of the contributions of Michaelis and Menten on the one hand and of Henri on the other. Rather than force the review into an unrealistic consensus, we consider it appropriate to leave the disagreements visible. (shrink)

We dedicate this special section to the memory of Eric H. Davidson, who died on the first of September 2015. Though he had been seriously ill for many years, his death was unexpected and a great shock for us.We dedicate the section, first, to a great scientist who passionately pursued the idea of a mechanistic explanation of development and evolution. Eric was a pioneer in the molecular biology of development and its relationship to evolution. One of the first to suggest (...) a model for gene regulation in higher organisms, he became the founder of the enormously successful concept of developmental gene regulatory networks. Central to his approach was the analysis of the characteristics of.. (shrink)