The phylogenetic position of the hagfish remains enigmatic. In contrast to molecular data that suggest monophyly of the cyclostomes, several morphological features imply a more ancestral state of this animal compared with the lampreys. To resolve this question requires an understanding of the embryology of the hagfish, especially of the neural crest. The early development of the hagfish has long remained a mystery. We collected a shallow‐water‐dwelling hagfish, Eptatretus burgeri, set up an aquarium tank designed to resemble its habitat, and (...) successfully obtained several embryos. By observing the histology and expression of genes known to play fundamental roles in the neural crest, we found that the hagfish crest develops as delaminating migratory cells, as in other vertebrates. We conclude that the delaminating neural crest is a vertebrate synapomorphy that seems to have appeared from the beginning of their evolutionary history, before the splitting away of the hagfish lineage. BioEssays 30:167–172, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

日常においてはいつも素通りされている豊かな経験の世界がある―。“自明”であるがゆえに眼を向けられることのないこの経験の世界を現象学は精査し、われわれにとっての「現実」が成立する構造を明るみに出す。創始 者フッサール以来続く哲学的営為の核心にあるものは何か。そしていまだ汲みつくせないその可能性とは。本書は粘り強い思索の手触りとともに、読者を生と世界を見つけなおす新たな思考へと誘う。.

Pockett has drawn an alternative conclusion from the data of Libet, Alberts, Wright, and Feinstein , and suggested that it takes 80 ms, rather than 500 ms, for the sensation evoked by a stimulus to enter awareness. Here, I suggest that our conscious sensation evolves over time, during the period from 80 to 500 ms after a stimulus, until the sensation is stably localized in space.

Early modern humans developed mental capabilities that were immeasurably greater than those of nonhuman primates. We see this in the rapid innovation in tool making, the development of complex language, and the creation of sophisticated art forms, none of which we find in our closest relatives. While we can readily observe the results of this high-order cognitive capacity, it is difficult to see how it could have developed. We take up the topic of cave art and archeoacoustics, particularly the discovery (...) that cave art is often closely connected to the acoustic properties of the cave chambers in which it is found. Apparently, early modern humans were able to detect the way sound reverberated in these chambers, and they painted artwork on surfaces that were acoustic “hot spots,” i.e., suitable for generating echoes. We argue that cave art is a form of cross-modality information transfer, in which acoustic signals are transformed into symbolic visual representations. This form of information transfer across modalities is an instance of how the symbolic mind of early modern humans was taking shape into concrete, externalized language. We also suggest that the earliest rock art found in Africa may constitute one of the first fossilized proxies for the expression of full-fledged human linguistic behavior. (shrink)

Using artificially synthesized stimuli, previous research has shown that cotton-top tamarin monkeys easily learn simple AB grammar sequences, but not the more complex AnBn sequences that require hierarchical structure. Humans have no trouble learning AnBn combinations. A more recent study, using similar artificially created stimuli, showed that there is a neuroanatomical difference in the brain between these two kinds of arrays. While the simpler AB sequences recruit the frontal operculum, the AnBn array recruits the phylogenetically newer Broca’s area. We propose (...) that on close inspection, reported vocal repertoires of Old World Monkeys show that these nonhuman primates are capable of calls that have two items in them, but never more than two. These are simple AB sequences, as predicted by previous research. In addition, we suggest the two-item call cannot be the result of a combinatorial operation that we see in human language, where the recursive operation of Merge allows for a potentially infinite array of structures. In our view, the two-item calls of nonhuman primates result from a dual-compartment frame into which each of the calls can fit without having to be combined by an operation such as Merge. (shrink)

In this paper, I propose a possible reinterpretation of phenomenology using a newly defined concept of ‘mediation.’ First, I address the question: What are the ‘things themselves’ that are given as the result of the phenomenological epoché? I would answer that they are neither material objects nor merely subjective experiences, but rather specific occurrences of ‘mediations.’ Second, under the influence of the Japanese philosopher Hajime Tanabe, I will define ‘mediation’ as a non-separable occurrence of differentiating and connecting. Third, I shall (...) claim that the concept of ‘phenomenon’ itself should be reinterpreted in terms of its character of mediation. Then, I will discuss central issues in phenomenology such as intentionality, time, and intersubjectivity in order to test the applicability of the proposed concept of mediation. To conclude, I shall summarize the potential of the idea that phenomenology can be reinterpreted using the concept of mediation. (shrink)

We revisit the EPR problem and make clear what is a correct comprehension of its problem. When one applies the quantum mechanics correctly, it will be shown that there is no paradox. According to these lines of thought, a quantum teleportation scheme without resort to the von Neumann projection postulate is presented.

Husserl’s theory of the phenomenological reduction is often explained by a radicalchange of attitude. Such an explanation is useful but sometimes misleading. TheIdea of Phenomenology clearly shows that the original idea of the reduction wasachieved through a radicalized critique of evidence. Although Husserl’s appealto evidence has often been criticized as an unjustified limitation of philosophicalthinking, a close examination of Husserl’s lectures reveals that the very ‘limitation’ to the phenomenological evidence breaks our naturalinclination toward objective identities and liberates our thinking from (...) the naturalbut misleading division between ‘transcendence’ and ‘immanence.’ Thus, thephenomenological reduction can be interpreted as a transition from the thinkingwithout regard to evidence to the philosophizing intrinsically mediatedby evidence, which can secure access for intuitive analysis to every conceivabletype of givenness insofar as it manifests itself. (shrink)

Many functional glycoproteins are expressed on the lymphocyte cell surface. Some of them carry O-linked oligosaccharides (O-glycans), which are conjugated through serine or threonine residues. During various biological processes, including T-cell activation, a tetrasaccharide on the T-cell surface is dramatically converted to a branched hexasaccharide, called core2 O-glycan. The same structural change in O-glycans is also found on the lymphocytes from patients with immunodeficiency conditions such as Wiskott-Aldrich syndrome and AIDS. Several studies revealing the roles of core2 O-glycans in immune (...) responses show that this is a biologically significant change. In particular, core2 O-glycans expressed on the cell surface reduce cell–cell interactions, thereby regulating immune responses. Furthermore, core2 O-glycan is a key backbone structure in forming selectin ligands. Thus, O-linked oligosaccharides, in particular those containing core2 branches, play vital roles in immune responses and may play dual roles in certain situations. This review will summarize the results obtained from various studies investigating the roles of O-glycans in immunological processes. BioEssays 23:46–53, 2001. © 2001 John Wiley & Sons, Inc. (shrink)

The aim of this paper is to reveal Socrates as a thorough democrat. In the first section, I will disprove the credibility of Xenophon’s Memorabilia, a common source for scholars who view Socrates as an antidemocratic thinker. I will then argue, in the second section, that the views of a few scholars who portray Socrates as a prodemocratic thinker represent a far-from-satisfactory depiction of his political views. In the third section, I will then demonstrate that Socrates’ criticism of democracy is (...) not of democracy itself nor of Athenian laws, but instead a criticism of a particular sort of democracy seen in the period of Athenian imperialism, and that it derives from his fundamental recognition of human ignorance. After pointing out Socrates’ special preference for the democratic laws of Athens, seen in the Crito, I will establish, in the fourth section, a preference in his philosophy showing him as a staunch democrat who upheld the concept of the rule of law. (shrink)

In theLysisSocrates deals with the problem of what is a friend and what is friendship. After giving an introduction and a synopsis of theLysisin section one, I explain, in section two, Socrates’ view that a true friend is “what is akin” or “what is belonging to oneself” which is what is taken from oneself and discovered in another person. When this happens among two persons, they become friends to each other. The content of what is akin is either a good (...) characteristic or ways or form of the soul. Friendship is the desire for what is akin. In section three I show that Socrates remains inaporiawhile he faces several problems. Unless he is able to answer such problems, he will not be truly confident about what is a friend. In section four I deal with and refute Penner’s and Rowe’s view that a true friend means wisdom. In section five I examine the view of friendship which occurs among people who share common deficit. As a conclusion, in section six, I reflect on the significance of my interpretation and the role of theLysisin Plato’s philosophy. (shrink)

This article considers Socrates's conception of courage in Plato's Socratic dialogues. Although the Laches, which is the only dialogue devoted in toto to a pursuit of the definition of courage, does not explicitly provide Socrates's definition of courage, I shall point out clues therein which contribute to an understanding of Socrates's conception of courage. The Protagoras is a peculiar dialogue in which Socrates himself offers a definition of courage. Attending to the dramatic structure and personalities of the dialogue, I will (...) point out that Socrates does not commit to the definition and that the hedonism and the definition of courage are used to disclose Protagoras's confusion regarding virtue. Following one of the clues within the Laches I will turn to the Apology and indicate Socrates's conception of courage which is based on his awareness of lack of knowledge of death and his religious conviction that nothing will happen for the good in life or in death. Finally I will show that such conception of Socratic courage satisfies the criteria in the Laches. (shrink)

Nous avons trois objectifs dans cet article. Le premier est de montrer la pensée et le comportement de Yasuma Takata (1883-1972), auteur quasiment inconnu en Occident, mais qui donna pourtant au Japon ses premières théories sociologiques et socio-économiques générales. Le deuxième est d’examiner comment ces pensée et comportement sont liés à la responsabilité de la guerre dans la seconde guerre mondiale. Le troisième consiste à montrer que cette pensée est profondément connectée au courant de la pensée japonaise moderne à travers (...) la théorie de Maruyama et des opinions des Ôe et Kawabata. Classification JEL : B15, B31, N45. (shrink)

There is growing evidence that individuals with social anxiety show impaired cortisol recovery after experiencing social evaluative stressors. Yet, little is known regarding the cognitive processes underlying such impaired cortisol recovery. The present study examined the effect of post-event processing (PEP), referred to as repetitive thinking about social situations, on cortisol recovery following a social stressor. Forty-two non-clinical university students (23 women, 19 men, mean age = 22.0 ± 2.0 years) completed the Trier Social Stress Test (TSST), followed by a (...) thought sampling procedure which assessed the frequency of PEP reflecting the TSST. A growth curve model showed PEP and social anxiety interactively predicted cortisol recovery. In particular, PEP predicted impaired cortisol recovery in those with low levels of social anxiety but not in those with high levels of social anxiety, which contradicted the initial hypothesis. These findings suggest that PEP is differentially associated with cortisol recovery depending on levels of social anxiety. The possible mechanisms underlying these findings were discussed in terms of protective inhibition framework. (shrink)

Transcendental reflection does not simply withdraw from natural life and go somewhere else. On the contrary, it is a self-elucidation of natural life performed within this life itself. However, natural life has an inherent automatic system for concealing itself. Therefore, in order to make manifest the truly natural state of natural life, we need a deliberate method of outfoxing the natural attitude as it constantly tries to trick us. If so, the transcendental perspective is closely related to Husserl’s perplexing concept (...) of “primal I”. It expresses a primitive perspective of our experience that cannot be identified with the first-person perspective. Phenomenology is not merely an investigation of experience from the first-person point of view, but a philosophical thinking from a “zero person” perspective that makes it possible for us to understand the relativity of our own first-person experience, and how it is related to other first-person experiences and the third-person perspective. (shrink)