We present an age-structured model for erythropoiesis in which the mortality of mature cells is described empirically by a physiologically realistic probability distribution of survival times. Under some assumptions, the model can be transformed into a system of delay differential equations with both constant and distributed delays. The stability of the equilibrium of this system and possible Hopf bifurcations are described for a number of probability distributions. Physiological motivation and interpretation of our results are provided.

When translated into concrete policy, any allocation of emissions leads to the attribution of emissions rights based on distributive justice. Consequently, the distributive justice approach legitimizes the corresponding amount of emissions. If a certain level of emissions can receive emissions rights, provided they are compatible with a certain emissions budget, to allocate emissions rights when the dangerous concentration level has been overshot could understate the need to preserve the functioning of a “balanced” climate system. From the perspective of Foucault’s archaeology (...) of knowledge, and with the purpose of assessing the epistemology of climate justice, it will be possible to question the possible importation of the mode of production of norms of social law into climate mitigation justice. Additionally, it will be questioned whether the amount of anthropogenic emissions rights can be provided by “the laws of nature” and whether and how the no‑harm principle can contribute to the epistemological relevance of the narrative of climate justice. (shrink)

This study examines Russian politics in the Soviet and post-Soviet eras using sociologist Robert Merton’s middle-range theory. It analyzes ideology, decision making, political culture, public opinion, and democratization and offers an innovative approach to the study of Russian politics in the twenty-first century.

Cet ouvrage vise à déployer la complexité de la philosophie cartésienne, à interroger l'effort de Descartes pour concilier les deux mouvements de l'existence humaine: la liberté qu'a le moi de mettre à distance ses objets de pensée et son plaisir à ressentir son incarnation corporelle, pourtant inexplicable. Il s'agit d'une présentation globale de la pensée cartésienne qui s'attache à dégager ses tensions problématiques.

La philosophie de Descartes est souvent associée à l'image d'une rationalité ascétique, fondée sur un exercice solitaire de la pensée, et hostile par principe aux passions humaines comme au sens commun. Cette image d'une rationalité hautaine, qui n'aurait rien à voir avec la tradition humaniste issue de la Renaissance, est celle que l'ouvrage entend remettre en question. L'oeuvre de Descartes s'y trouve éclairée par la problématique humaniste de la civilité et par son effort pour définir un moyen terme vertueux entre (...) une censure ascétique de la nature humaine et un abandon à la spontanéité aveugle de la sensibilité. Dégager la perspective d'une "civilité de la raison cartésienne" c'est aussi s'efforcer de construire pour l'humanisme un fondement métaphysique et rationnel, lié tout à la fois à l'idée théologique d'une "bonne nature" et à une description phénoménologique de notre expérience du monde. Aussi s'agit-il de restituer non pas seulement le dessin doctrinal et argumentatif de la philosophie de Descartes, mais également la couleur et la vitalité associées aux tonalités éthiques et affectives d'une écriture à travers laquelle seule se délivre la conception cartésienne de la subjectivité. (shrink)

Cet article étudie la présence de la valeur humaniste de "douceur" chez Montaigne et Descartes, dans le champ de l'éducation, des relations humaines, mais aussi de la méthode cartésienne pour bien conduire son entendement. Ainsi, la méthode doit faire preuve de douceur dans la culture de l'âme, et Descartes dans l'Epître à Voet décrit la douceur comme une composante essentielle des "lois de l'amitié" entre les hommes. Il s'agit donc de proposer une interprétation nouvelle et humaniste de la pensée cartésienne, (...) qui porte à la fois sur la morale et la recherche de la vérité. (shrink)

This book, first published in 1997, is an introductory overview of decision theory. It is completely non-technical, without a single formula in the book. Written in a crisp and clear style it succinctly covers the full range of philosophical issues of rationality and decision theory, including game theory, social choice theory, prisoner's dilemma and much else. The book aims to expand the scope and enrich the foundations of decision theory. By addressing such issues as ambivalence, inner conflict, and the constraints (...) imposed upon us by our attachments to others, Frederic Schick reveals that our thinking is often more subtle than standard theories of rationality allow. Only a theory that respects that subtlety can illumine what is otherwise puzzling. The book contains many examples drawn from history and literature dealing with subjects such as love, war, friendship, and crime. (shrink)

Background: Informed consent for genetic tests is a well-established practice. It should be based on good quality information and in keeping with the patient’s values. Existing informed consent assessment tools assess knowledge and values. Nevertheless, there is no consensus on what specific elements need to be discussed or considered in the consent process for genetic tests.Methods: We performed a systematic review to identify all factors involved in the decision-making and consent process about genetic testing, from the perspective of patients. Through (...) public databases, we identified studies reporting factors that influence the decision to accept or decline genetic testing. Studies were included if they reported the perspective of patients or at-risk individuals. All articles were thematically coded.Results: 1989 articles were reviewed: 70 met inclusion criteria and 12 additional articles were identified through the references of included studies. Coding of the 82 articles led to the identification of 45 factors involved in decision-making and consent, which were initially divided into three domains: in favor of, against or with an undetermined influence on genetic testing. Each factor was also divided into three subdomains relating to the informed choice concept: knowledge, values or other. The factors in the “other” subdomain were all related to the context of testing (e.g. timing, cost, influence of family members, etc), and were present in all three domains.Conclusions: We describe the network of factors contributing to decision-making and consent process and identify the context of genetic testing as a third component to influence this process. Future studies should consider the evaluation of contextual factors as an important and relevant component of the consent and decision-making process about genetic tests. Based on these results, we plan to develop and test a more comprehensive tool to assess informed consent for genetic testing. (shrink)

In this book Frederic Schick develops his challenge to standard decision theory. He argues that talk of the beliefs and desires of an agent is not sufficient to explain choices. To account for a given choice we need to take into consideration how the agent understands the problem, how he sees in a selective way the options open to him. The author applies his new logic to a host of common human predicaments. Why do people in choice experiments act so (...) often against expectations? Why do people cooperate in situations where textbook logic predicts that they won't? What exactly is weakness of will? What are people reporting when they say their lives have no meaning for them? This book questions the foundations of technical and philosophical decision theory and will appeal to all those who work in that field, be they philosophers, economists and psychologists. (shrink)

Two different kinds of collections have been used to anticipate influenza pandemics: viral strains and bird specimens. These collections have been organized in museums and data banks to fill the gaps when specimens were decaying or when viral strains were missing. This article asks how collecting practices changed when such collections integrated specimens from China, considered a reservoir of influenza viruses and bird species, following a recurrent critical trope that Chinese specimens were missing. The article shows that techniques for hunting (...) viruses and birds were used to accumulate information so as to mitigate the global threat of species extinction. It suggests that in sentinel territories, museums transform samples and specimens into signs and images of future catastrophic events. (shrink)

The intersection of AI and neurotechnology has resulted in an increasing number of medical and non-medical applications and has sparked debate over the need for new human rights, or “neurorights,”...

In this book, Frederic L. Pryor uses the concept of structural complexity to show how changes in the population, the labour force, the structure of industry, the financial system, foreign and domestic trade, and the government sector are related to the same general trend in the US economic system. He also investigates the impact of these changes on the functioning of the system, exploring such matters as the long-term rising unemployment rate, the allegedly increasing volatility of the economy, the changing (...) degree of competition, and the evolving economic role of the government. The discussion is aimed at those who wish to view the economy as a whole and who are concerned with problems of understanding an economy that is becoming increasingly complex along many different dimensions. For specialists a number of appendices discuss a variety of technical issues. (shrink)

La logique classique, qui repose sur trois principes fondamentaux (d'identité, de non-contradiction et de tiers-exclu), a pu séduire par son efficacité orientée vers l'être, elle permet d'appréhender la cohérence du réel, donc de développer les savoirs. Pour autant, sa puissance s'avère limitée dans certaines situations des limitations internes des formalismes à l'apparition de nouveaux objets paradoxaux, la science du XXe siècle a été confrontée à une crise de ses fondements dont elle n'est pas encore sortie. Or, s'affranchir de ce qui (...) vient en nous entraver la pensée a été un enjeu pour des courants soucieux de fonder leur rigueur démonstrative sur un au-delà de l'être. Dans la lignée de l'hénologie néoplatonicienne, ces modes d'explication ont néanmoins souvent été jugés irrationnels, mystiques ou simplement absurdes. À l'aide des logiques non standards contemporaines, c'est une étude systémique de ces positions qui est ici envisagée à travers la critique de l'hégémonie des trois grands principes logiques grâce à la logique intuitionniste, il devient possible de construire rigoureusement la notion de néant suressentiel; grâce aux logiques paraconsistantes, les contradictions et les paradoxes qu'une telle dialectique engendre perdent leur caractère irrationnel; enfin, grâce aux traditions logiques indiennes et japonaises, le principe d'identité peut lui-même être questionné. Cette remise en cause radicale de nos certitudes les mieux ancrées permet ultimement de dégager de nouvelles perspectives à la pensée logique."--Page 4 of cover. (shrink)

ABSTRACTAs a comment on the debate between Dave Elder-Vass and Leigh Price, I propose a dialogue between Bhaskar and Habermas. If we could introduce critical realism into critical theory, we might...

"Of all the theorists of the first Critical Theory, Horkheimer was the one who most explicitly expressed his interest in moral theory. He concludes his research with the impossibility of any moral system possessing its own foundations. Habermas challenged Horkheimer's judgment that it was impossible to establish the completeness of a moral system without a transcendent foundation, and proposed communicational reason as an immanent foundation.

The following text is a translation of Semyon Frank’s “L’intuition fondamentale de Bergson” published in Henri Bergson: Essais et témoignages inédits, edited by Albert Béguin and Pierre Thévenaz, Neuchâtel: Éditions de la Baconnière, 1941. In this article, Frank addresses Bergson’s notion of intuition, his anti-intellectualism, his mysticism, his closeness to Lebensphilosophie, the notion of lived experience, the distinction between intuition as pure contemplation and intuition as living knowledge, the distinction between cognition of the atemporal essence of reality and cognition of (...) the world of becoming, pragmatism, the disinterested and open intuitive spiritual attitude vs the utilitarian attitude of social groups closed in on themselves, the transrational vs the irrational, spiritual life, psychic life, the Absolute, and the temporal flux. The article contains criticisms of Bergson on the issues of time and intuition: the durée, the intuitive time, is incomprehensible without an atemporal foundation. Therefore, according to Frank, Plato was correct—contra Bergson—to define time as the moving image of eternity. And, if there is such an atemporal foundation, then, contrary to what Bergson seems to think, intuition as living knowledge cannot be the sole mode of intuition. Moreover, unlike what Bergson appears to think, an intuition of the Absolute would be an intuition of the transrational rather than of the irrational. The translation is preceded by an introduction tracing the genesis of the article, which was commissioned by the Swiss philosopher Pierre Thévenaz. (shrink)

The philosophical assumptions that organize moral sociology as practical philosophy are the outcome of a secular quest to investigate the principles, norms and values behind the constitution of society. As a protracted response to the whole utilitarian-atomistic-individualistic tradition that systematically deemphasizes the constitutive role that morality plays in the structuration of self and society, the sociological tradition has continued, by its own means, the tradition of moral and practical philosophy in theoretically informed empirical research of social practices. Going back to (...) classic moral philosophy, I want to show in this article how social theory is involved in the quest for ‘the good life with and for the others in just institutions’ (Ricoeur). (shrink)

Cet article commente une lettre de jeunesse d’un Hume qui traverse une grave dépression nerveuse. Cet épisode pourtant n’a rien d’anecdotique, parce que Hume y théorise déjà le rapport entre la mélancolie, diagnostiquée à l’époque comme la maladie des lettrés, et sa manière de philosopher.

In their article, Herrera-Ferra et al. (2023) highlight how the progress and implementation of neurotechnology, especially in conjunction with artificial intelligence, have revealed potential impli...

Soul beliefs are universal among religious folk but vary tremendously from culture to culture, In fact, in tribal societies without formal religious dogmas, soul beliefs can vary from individual to individual. A review of notions regarding the soul (or souls) amongst tribal and post-tribal societies does evidence, nonetheless, a recurring pattern of focus on the soul envisaged as the vital life energy of the body and/or as encapsulating one of more mental faculties. Not surprisingly, theories as to the psychological basis (...) for soul belief vary as well, but a strong case can be advanced that at its core, soul belief is about the essence of the self, which involves the psychological process of ipseity. (shrink)

À quoi ressemblerait la planète Terre si on ne la considérait qu’à travers quelques chiffres clés? Quelles échelles incommensurables apparaîtraient à la lumière de cette mise en chiffre? Quels redimensionnements de nos écologies politiques?