In this important study D. M. Armstrong offers a comprehensive system of analytical metaphysics that synthesises but also develops his thinking over the last twenty years. Armstrong's analysis, which acknowledges the 'logical atomism' of Russell and Wittgenstein, makes facts the fundamental constituents of the world, examining properties, relations, numbers, classes, possibility and necessity, dispositions, causes and laws. All these, it is argued, find their place and can be understood inside a scheme of states of affairs. This is a comprehensive and (...) rigorously this-worldly account of the most general features of reality, argued from a distinctive philosophical perspective, and it will appeal to a wide readership in analytical philosophy. (shrink)

Antimicrobial resistance (AMR) poses an increasing threat to patient care and population health and there is a growing need for novel therapies to tackle AMR. Bacteriophage (phage) therapy is a re-emerging antimicrobial strategy with the potential to transform how bacterial infections are treated in patients and populations. Currently, in the UK, phages can be used as unlicensed medicinal products on a ‘named-patient’ basis. We make an ethical case for why it is crucially important for the UK to invest in Good (...) Manufacturing Practice (GMP) for both ongoing unlicensed and future licensed phage therapy. Access to phages produced to GMP (GMP phages) will ensure effective patient care and better outcomes as well as health systems benefits. The UK also has the potential to become a global leader in the timely and cost-efficient manufacturing and supply of a therapy that meets internationally recognised standards. (shrink)

Originally published in 1936, this book presents the ancient Greek text of the paraphrases and quotations of Zeno's philosophical arguments, together with a facing-page English translation and editorial commentary. Detailed notes are incorporated throughout and a bibliography is also included. This book will be of value to anyone with an interest in Zeno and ancient philosophy.

The subject of the present inquiry is the approach-to-the-truth research, which started with the publication of Sir Karl Popper's Conjectures and Refutations. In the decade before this publication, Popper fiercely attacked the ideas of Rudolf Carnap about confirmation and induction; and ten years later, in the famous tenth chapter of Conjectures he introduced his own ideas about scientific progress and verisimilitude. Abhorring inductivism for its apprecia tion of logical weakness rather than strength, Popper tried to show that fallibilism could serve (...) the purpose of approach to the truth. To substantiate this idea he formalized the common sense intuition about preferences, that is: B is to be preferred to A if B has more advantages andfewer drawbacks than A. In 1974, however, David Millerand Pavel Tichy proved that Popper's formal explication could not be used to compare false theories. Subsequently, many researchers proposed alternatives or tried to improve Popper's original definition. (shrink)

Open peer commentary on the article “Sensorimotor Direct Realism: How We Enact Our World” by Michael Beaton. Upshot: In light of the construal of sensorimotor theory offered by the target article, this commentary examines the role the theory should admit for internal representation.

Both the concept of a Darwinian tree of life (TOL) and the possibility of its accurate reconstruction have been much criticized. Criticisms mostly revolve around the extensive occurrence of lateral gene transfer (LGT), instances of uptake of complete organisms to become organelles (with the associated subsequent gene transfer to the nucleus), as well as the implications of more subtle aspects of the biological species concept. Here we argue that none of these criticisms are sufficient to abandon the valuable TOL concept (...) and the biological realities it captures. Especially important is the need to conceptually distinguish between organismal trees and gene trees, which necessitates incorporating insights of widely occurring LGT into modern evolutionary theory. We demonstrate that all criticisms, while based on important new findings, do not invalidate the TOL. After considering the implications of these new insights, we find that the contours of evolution are best represented by a TOL. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Philosophy 38.1 (2000) 87-101 [Access article in PDF] Collingwood on Re-Enactment and The Identity of Thought Giuseppina D'oro University of Keele Collingwood's The Idea of History is often discussed in the context of the issue of the reducibility/non-reducibility of explanations in the social sciences to explanations in the natural sciences. In the 1950s and 60s, following the publication of Hempel's influential article, "The Function (...) of General Laws in History,"1 many looked at Collingwood's defence of the autonomy of history as providing the appropriate conceptual resources to counter Hempel's claim that explanations in history and in the natural sciences share the same logical structure. Collingwood was recruited as an ally in a number of debates in analytical philosophy of history with a view to clarifying the nature of appropriately historical explanations and the proper subject matter of historical science. In this paper, I wish to consider Collingwood's account of historical understanding from a related but distinct perspective, that is, I wish to consider re-enactment from the perspective of Collingwood's (controversial) claim that thought stands outside time, and that it is because thought stands outside time that it is possible to understand the thoughts of other agents, including those of agents who lived in a distant past. Although Collingwood's account of re-enactment is developed in the context of his philosophy of history, it addresses some very general issues within the philosophy of mind. It is with Collingwood's approach to these general issues that the present paper is concerned: First, I explicate Collingwood's account of re-enactment against the background of his philosophy of mind and, second, attempt to show that one important goal of Collingwood's account of re-enactment is to undermine a certain type of scepticism about the possibility of sharing the thoughts of others, rather than provide a straightforward refutation of this sceptical position. While I believe Collingwood's claim that thought stands outside time to have important repercussions on how to understand [End Page 87] issues more closely related to the philosophy of history, I will not attempt, for reasons of space, to cash out these implications here.In The Idea of History2 the concept of re-enactment is expounded largely via an engagement with an imaginary objector. The position that Collingwood attributes to the imaginary objector can be preliminarily summarized as saying that the objector identifies thoughts with token acts of thinking which can be spatio-temporally located, rather than with the propositional content expressed by those token acts. It is because the objector holds thoughts to be token acts which can be spatio-temporally located that s/he denies that two agents can have or share one and the same thought. Collingwood's reply to the imaginary objector relies on a philosophy of mind that is developed elsewhere3 but whose key elements are presupposed by his discussion of re-enactment in The Idea of History, and essential to an understanding of Collingwood's position.4An important aspect of Collingwood's philosophy of mind concerns his understanding of what is meant by an 'object of thought': When I call a thing subjective I mean that it is or pertains to a subject or conscious mind. When I call it objective I mean that it is or pertains to the object of which such a mind is conscious. I do not call a real rose objective and an imaginary one subjective, or the molecules in it objective and the beauty of it subjective. A real rose I call real and an imaginary rose I call imaginary; and I call them both objective because they are the objects of a perceiving and imagining mind respectively. (SM, 11)5For the sake of clarity I shall refer to the subjective/objective distinction as used by Collingwood as subjective2 and objective2 and to the subjective/objective distinction against which it is contrasted as subjective1 and objective1. Objective1 means existing in... (shrink)

Many studies examine a stressors-professional burnout (PB) relation, but only few consider the role of ethical conflicts (ECs) in this context. The aim of this study was to characterize ECs' frequency and level of burden with them among nurses and to establish the relations between ECs' frequency, burden and PB. One hundred nurses participated in this study. ECs' frequency and burden were tested with an originally developed questionnaire. PB was examined with Maslach Burnout Inventory. Most frequent ECs concerned a nurse-patient (...) relationship. PB was positively related to ECs' frequency (r = .54; p = .001) and burden (r = .22; p = .03). Frequency of specific conflict did not imply burden with it and vice versa. ECs' frequency seems more important for PB than a level of burden with them. The most frequent and the most burdening conflicts may lead to development of PB but the less frequent and less burdening ones are also dangerous. (shrink)

Dowsing, water-witching, divining – the procedure seeks a flow or spring beneath the surface of earth. So too this inquiry attempts to locate and sound the meanings associated with the polestar of Thalean considerations, ὕδωρ, that course beneath the interpretative strata of an overly-familiar tradition grounded in the principles of clarity and intelligibility. If these principles are held in suspension, what meanings flow from the Thalean considerations of ὕδωρ? A twofold task guides this inquiry. First is to show opacity as (...) the primary valence of ὕδωρ, challenging the prevailing tendency to imagine Thales and other Milesian thinkers as positing a principle of clarity in the form of what can be brought under the Aristotelean concept of underlying thing and matter. Second, in the course of drawing up the opacity of ὕδωρ form varied archaic sources emerge some connections to important terms for Greek thinking: φύσις, λόγος, ἀλήθεια. (shrink)

Papers presented at the National Seminar on "Dharma, Virtue and Morality : the Indian Ideal of Human Perfection, held at Kanpur in 2005.

In this paper we suggest adding to predicate modal and temporal logic a locality predicate W which gives names to worlds (or time points). We also study an equal time predicate D(x, y)which states that two time points are at the same distance from the root. We provide the systems studied with complete axiomatizations and illustrate the expressive power gained for modal logic by simulating other logics. The completeness proofs rely on the fairly intuitive notion of a configuration in order (...) to use a proof technique similar to a Henkin completion mixed with a tableau construction. The main elements of the completeness proofs are given for each case, while purely technical results are grouped in the appendix. (shrink)

In the opening passage of the Breviarium of Festus we read the following: ‘… ac morem secutus calculonum, qui ingentes summas aeris breuioribus exprimunt, res gestas signabo, non eloquar. Accipe ergo quod breuiter dictis breuis conputetur …’ The problem that I should like briefly to discuss in the following study is: Who were the calculones, ‘qui ingentes surnmas aeris breuioribus exprimunt’? This term calculo, and indeed the whole problematic clause can, I suggest, only be fully understood and appreciated in the (...) light of monetary developments of the later fourth century. (shrink)