What happens when neuroscientific knowledges move from laboratories and clinics into therapeutic settings concerned with the care of children? ‘Brain-based parenting’ is a set of discourses and practices emerging at the confluence of attachment theory, neuroscience, psychotherapy and social work. The neuroscientific knowledges involved understand affective states such as fear, anger and intimacy as dynamic patterns of coordination between brain localities, as well as flows of biochemical signals via hormones such as cortisol. Drawing on our own attempts to adopt brain-based (...) parenting, and engaging with various strands and critiques of new materialism and affect theory, we explore the ways in which the social sciences and humanities might fruitfully engage with neuroscientific concepts and affects. How does science-affected indeterminacy, with all its promises of ontological and experiential agency, help us to observe, wait, bind or hold together volatile mixtures of habit, speech and action? (shrink)

How can one ‘see’ the operationalization of contemporary visual culture, given the imperceptibility and apparent automation of so many processes and dimensions of visuality? Seeing – as a position from a singular mode of observation – has become problematic since many visual elements, techniques, and forms of observing are highly distributed through data practices of collection, analysis and prediction. Such practices are subtended by visual cultural techniques that are grounded in the development of image collections, image formatting and hardware design. (...) In this article, we analyze recent transformations in forms of prediction and data analytics associated with spectacular performances of computation. We analyze how transformations in the collection and accumulation of images as ensembles by platforms have a qualitative and material effect on the emergent sociotechnicality of platform ‘life’ and ‘perception’. Reconstructing the visual transformations that allow artificial intelligence assemblages to operate allows some sense of their heteronomous materiality and contingency. (shrink)

This article analyses a specific piece of computer code, the Linux operating system kernel, as an example of how technical operationality figures in contemporary culture. The analysis works at two levels. First of all, it attempts to account for the increasing visibility and significance of code or software-related events. Second, it seeks to extend familiar concepts of performativity to include cultural processes in which the creation of meaning is not central, and in which processes of circulation play a primary role. (...) The analysis concentrates on the practices and patterns of circulation of Linux through versions, distributions, clones and reconfigurations. It argues that technical ‘culture-objects’ such as Linux take on a social existence within contemporary technological cultures because of the authorizing contexts in which the reading, writing and execution of code occur. The ‘force’ or performance of certain technical objects, their operationality, can be understood more as the stabilized nexus of diverse social practices, rules and personae than as a formal property of the objects themselves. (shrink)

Functional MRI shows promise as a candidate prognostication method in acutely comatose patients following severe brain injury. However, further research is needed before this technique becomes appropriate for clinical practice. Drawing on a clinical case, we investigate the process of obtaining informed consent for this kind of research and identify four ethical issues. After describing each issue, we propose potential solutions which would make a patient’s participation in research compatible with her rights and interests. First, we defend the need for (...) traditional proxy consent against two alternative approaches. Second, we examine the impact of the intensive care unit environment on the informed consent process. Third, we discuss the therapeutic misconception and its potential influence on informed consent. Finally, we deal with issues of timing in recruiting participants and related factors which may affect the risks of participation. (shrink)

This article responds to two problems confronting social and human sciences: how to relate to digital data, inasmuch as it challenges established social science methods; and how to relate to life sciences, insofar as they produce knowledge that impinges on our own ways of knowing. In a case study of proteomics, we explore how digital devices grapple with large-scale multiples – of molecules, databases, machines and people. We analyse one particular visual device, a cluster-heatmap, produced by scientists by mining data (...) from a large number of experiments on human blood plasma proteins. These proteins make up a myriad multiple whose identity shifts in many ways. Rather than displaying data about proteins, the heatmap constructs a view of the differences and similarities between experiments. We find this attempt to construct a view on many things at once instructive in thinking about multiples more generally. Instead of flattening molecular ‘life itself’, this visual device superimposes layers of digital devices and techniques from a wide variety of disciplines. This layering suggests a different way of relating to the life sciences more generally: rather than what they know, how they know might be of use to social and human sciences when attending to multiplicities. (shrink)

Accounts of big data practices often assume that they target individuals. Personalization, with all the risks of discrimination and bias it entails, has been the critical focus in accounts of consumption, government, social media, and health. This paper argues that personalization through models using large-scale data is part of a more expansive change in probabilization that, in principle, is not reducible to individual or ‘personal’ attributes and actions. It describes the ‘personalization’ of an online grocery shopping recommender system to list (...) a small number of grocery items of personal relevance for each of the millions of online grocery shoppers at a major UK supermarket chain. Drawing on a theory of probability proposed by the philosopher of science Karl Popper and anthropological work on shopping, it suggests that the attempt to generate personalized predictions necessarily incorporates impersonal relations to others and things. Using a mixture of discourse analysis and code-based reconstruction of key elements of the recommender system, it suggests that personalization is one facet of an open-ended weave of propensities associated with people and things in contemporary big data configurations. The paper explores how, in the context of recommender systems, the constitutive incompleteness of shopping lists, their propensity to expand or change, might be more important than their capacity to be personalized. (shrink)

The connections between forms of code and coding and the many crises that currently afflict the contemporary world run deep. Code and crisis in our time mutually define, and seemingly prolong, each other in ‘infinite branching graphs’ of decision problems. There is a growing academic literature that investigates digital code and software from a wide range of perspectives –power, subjectivity, governmentality, urban life, surveillance and control, biopolitics or neoliberal capitalism. The various strands in this literature are reflected in the papers (...) that comprise this special issue. They address topics ranging from social networks, mass media, financial markets and academic plagiarism to highway engineering in relation to the dynamics and diversity of crises. Against this backdrop, the purpose of this essay is to highlight and explore some of the underlying themes connecting codes and codings and the production and apprehension of ‘crisis’. We analyse how the ever-increasing intermediation of contemporary life by codes of various kinds has been closely shadowed by a proliferation of crises. We discuss three related aspects of the coupling of code and crisis (signification, performativity and excess) running across these seemingly diverse topics. We and the other contributors in this special issue seek to go beyond the restricted (and often restricting) understanding of code as the language of machines. Rather, we view code qua programs and algorithms as epitomizing a much broader phenomenon. The codes that we live, and that we live by, also tell us about the ways in which the ‘will to power’ and the 'will to knowledge' tend to be enacted in the contemporary world. (shrink)

How could social scientists and cultural theorists take responsibility in engaging with science? How might they develop an experimental sensibility to the links between the production of knowledge and the production of existence or forms of life? Critically outlining key fields in the social and cultural studies of science, we interrogate a number of approaches to these questions. The first approach tries to make sense of how science operates in relation to economic, political and cultural forces. The second analyses science (...) as a form of embodied work or practice. The third engages with science as collaborative-collective elaboration of events, ranging across cultural theory, contemporary art and participant ethnographies. This outline sketches a vector of responsibility across this diverse range of engagements, suggesting that contemporary movements between science and other knowledges constitute ethical and political imperatives. (shrink)

What does it mean to have an Anthropocene body? The Anthropocene period is putatively defined by flows of hydrocarbons and hydrocarbon derivatives (fuels, plastics, fertilizers, etc.), and the very term ‘Anthropocene’ suggests an increasing awareness of the finitude and contingency of contemporary corporealities. This article explores the idea of modelling an Anthropocene body as a living/non-living metabolic process. While identifying bodies with molecules raises a host of problems, metabolism and hydrocarbon biomolecules display a gamut of forms of possession and ways (...) of having a body. Conversion between living and non-living forms of possession can be traced in contemporary genomic science and particularly in synthetic biology as they engineer microbes to produce next-generation biofuels. In contrast to fossil fuels, these fuels derive from genomically re-engineered microbes that digest biomass or photosynthesize to produce hydrocarbons. The problematic contemporary production of these fuels might help us to articulate what it means to have a body as a metabolic manifold of living and non-living forms of possession. (shrink)

In the ways that they currently link images and bodies, online computer games are not just a new form of commodity. As toys, they also materialise a collective, historical temporality. Disjunctions in the timing and spacing of action in computer game play suggest a different kind of temporality might be involved in the formation of contemporary collectives. These games highlight the role of ‘realtime’ in the constitution of an experience of speed. Through Giorgio Agamben's notion of the whatever body, and (...) a particular realtime game, this paper argues that computer games can help locate certain rhythms and times associated with globalised informatic collectives. The whatever body provides a way of negotiating the globalised yet inessential commonality of information, in terms of a temporality which wavers between a‐historical synchronisation and singular events. (shrink)

The paper asks how certain zones of technical practice or technologies come to matter as "the Technological", a way of construing political change in terms of technical innovation and invention. The social construction of technology (SCOT) established that things mediate social relations, and that social practices are constantly needed to maintain the workability of technologies. It also linked the production, representation and use of contemporary technologies to scientific knowledge. However, it did all this at a certain cost. To understand something (...) as socially constructed implies that it can be positioned on a pre-given social grid. Making this understanding stick risks affronting others with the claim that their position is not singular, only ordinary. It also runs the risk of not having purchase on those aspects of technological relationality that overflow the framing context of the social (Callon et al. 2002). Building on the ground prepared by SCOT and relying on the work of (Stengers 2000) and (Simondon 1964, 1989), the paper discusses how technologies could be understood as relational events within the contemporary political space. Developing an account of technologies centred on relationality, this paper outlines an epistemology and ontology of the anomalies of technological events, and suggests how excess could explain the Technological. (shrink)

Wie unterscheidet sich ein Betriebssystem wie bspw. Linux von einer Mikrobe? Der Beitrag untersucht, wie technische Objekte im »Jahrhundert der Biologie« aufgefasst werden. Anhand des Werks von Gilbert Simondon wird gefragt, welche Existenzweisen biotechnische Objekte aufweisen. Die Prozesse von Abstraktion und Konkretisierung, die auf dem Feld der Synthetischen Biologie stattfinden, können einen Weg aufweisen, diese Fragen zu beantworten. How does a computer operating system such as Linux differ from a microbe? This paper explores how technical objects are envisaged in the (...) »century of biology«. Via the work of Gilbert Simondon, it asks what modes of existence biotechnical objects will display. The processes of abstraction and concretisation taking place in the field of synthetic biology offer one way to address these questions. (shrink)

How does a computer operating system such as Linux differ from a microbe? This paper explores how technical objects are envisaged in the »century of biology«. Via the work of Gilbert Simondon, it asks what modes of existence biotechnical objects will display. The processes of abstraction and concretisation taking place in the field of synthetic biology offer one way to address these questions.

Contemporary complexity sciences claim a literal, non-metaphorical applicability to physical, economic, social and cultural events. They envision the development of a general social or historical physics. Conversely, in the social sciences and humanities, complexity sciences have been typically treated as a source of new metaphors or tropes to be used in theory-building. Can there be a critical social or historical physics that is not a world-view and that does not treat science as a source of metaphors? The Lorenz attractor figures (...) centrally in the history of complexity science as a popular image of ‘deterministic chaos’ and the ‘butterfly effect’, as an indication of how far complexity science has progressed in the last two decades, and, as this article argues, as an event whose multiplicity of interpretations attests to the problem it raises, the problem of generality associated with complexity. Via the Lorenz attractor, the article examines three attempts to treat complexity non-metaphorically in recent theoretical work. In these accounts, the attractor performs several different functions. It forms part of a re-engineered concept of multiplicity, it helps conceptualize feeling or sensitivity, and it raises the general problem of practice in theory-building. (shrink)

Patient outcome after serious brain injury is highly variable. Following a period of coma, some patients recover while others progress into a vegetative state (unresponsive wakefulness syndrome) or minimally conscious state. In both cases, assessment is difficult and misdiagnosis may be as high as 43%. Recent advances in neuroimaging suggest a solution. Both functional magnetic resonance imaging and electroencephalography have been used to detect residual cognitive function in vegetative and minimally conscious patients. Neuroimaging may improve diagnosis and prognostication. These techniques (...) are beginning to be applied to comatose patients soon after injury. Evidence of preserved cognitive function may predict recovery, and this information would help families and health providers. Complex ethical issues arise due to the vulnerability of patients and families, difficulties interpreting negative results, restriction of communication to “yes” or “no” answers, and cost. We seek to investigate ethical issues in the use of neuroimaging in behaviorally nonresponsive patients who have suffered serious brain injury. The objectives of this research are to: (1) create an approach to capacity assessment using neuroimaging; (2) develop an ethics of welfare framework to guide considerations of quality of life; (3) explore the impact of neuroimaging on families; and, (4) analyze the ethics of the use of neuroimaging in comatose patients. (shrink)

Recent accounts of “the biological” emphasize its thoroughgoing transformation. Accounts of biomedicalization, biotechnology, biopower, biocapital, and bioeconomy tend to agree that twentieth- and twenty-first-century life sciences transform the object of biology, the biological. Amidst so much transformation, we explore attempts to stabilize the biological through standards. We ask: how do standards handle the biological in transformation? Based on ethnographic research, the article discusses three contemporary postgenomic standards that classify, construct, or identify biological forms: the Barcoding of Life Initiative, the BioBricks (...) Assembly Standard, and the Proteomics Standards Initiative. We rely on recent critical analyses of standardization to suggest that any attempt to attribute a fixed property to the biological actually multiplies dependencies between values, materials, and human and nonhuman agents. We highlight ways in which these biological standards cross-validate life forms with forms of life such as publics, infrastructures, and forms of disciplinary compromise. Attempts to standardize the biological, we suggest, offer a good way to see how a life form is always also a form of life. (shrink)

Descartes with his sharp separation of the mental and the physical set the stage for the philosophy of mind for the next 350 years. Philosopher Patrick T. Mackenzie finds in the later writings of Wittgenstein the suggestion that Descartes got off on the wrong foot. Following Wittgenstein's lead, Mackenzie argues that instead of analyzing our human nature as a composite of mind and body, we should view ourselves as whole persons. One of the dividends of this approach to (...) the mind-body problem is that it provides us with a resolution to the problem of human freedom—i.e., how can a human being be free if his or her body (including the brain) belongs to a deterministic world? Mackenzie here argues that the person is largely free even though the movements of the body are determined by neurophysiological events. He takes the same approach to the philosophy of mind as that taken by M.R.Bennett and P.M.S.Hacker in their recent and controversial book, The Philosophical Foundations of Neuroscience. Mackenzie's approach is, however, much more accessible. Students of philosophy and philosophers interested in the problem of human freedom will welcome Mackenzie's fresh approach, especially those disenchanted by the present list of mind-body "isms.". (shrink)

A Brief History of the Philosophy of Time is a concise and accessible survey of the history of philosophical and scientific developments in understanding time and our experience of time. It discusses prominent ideas about the nature of time, plus many subsidiary puzzles about time, from the classical period through the present.

Historical sciences like paleontology and archaeology have uncovered unimagined, remarkable and mysterious worlds in the deep past. How should we understand the success of these sciences? What is the relationship between knowledge and history? In Scientific Knowledge and the Deep Past: History Matters, Adrian Currie examines recent paleontological work on the great changes that occurred during the Cretaceous period - the emergence of flowering plants, the splitting of the mega-continent Gondwana, and the eventual fall of the dinosaurs - to (...) analyse the knowledge of historical scientists, and to reflect upon the nature of history. He argues that distinctively historical processes are 'peculiar': they have the capacity to generate their own highly specific dynamics and rules. This peculiarity, Currie argues, also explains the historian's interest in narratives and stories: the contingency, complexity and peculiarity of the past demands a narrative treatment. Overall, Currie argues that history matters for knowledge. (shrink)

The character of computational modelling of cognition depends on an underlying theory of representation. Classical cognitive science has exploited the syntax/semantics theory of representation that derives from logic. But this has had the consequence that the kind of psychological explanation supported by classical cognitive science is " _conceptualist_: " psychological phenomena are modelled in terms of relations that hold between concepts, and between the sensors/effectors and concepts. This kind of explanation is inappropriate for the Proper Treatment of Connectionism.

John Scottus Eriugena (d. ca. 877) is regarded as the most important philosopher and theologian in the Latin West from the death of Boethius until the thirteenth century. He incorporated his understanding of Latin sources, Ambrose, Augustine, Boethius and Greek sources, including the Cappadocian Fathers, Pseudo-Dionysius, and Maximus Confessor, into a metaphysics structured on Aristotle's Categories, from which he developed Christian Neoplatonist theology that continues to stimulate 21st-century theologians. This collection of essays provides an overview of the latest scholarship on (...) various aspects of Eriugena's thought and writings, including his Irish background, his use of Greek theologians, his Scripture hermeneutics, his understanding of Aristotelian logic, Christology, and the impact he had on contemporary and later theological traditions. Contributors: David Albertson, Joel Barstad, John Contreni, Christophe Erismann, John Gavin, Adrian Guiu, Michael Harrington, Catherine Kavanagh, A. Kijewska, Stephen Lahey, Elena Lloyd-Sidle, Bernard McGinn, Ernesto Sergio Mainoldi, Dermot Moran, Giulio D'Onofrio, Willemien Otten, and Alfred Siewers. (shrink)

This volume will be an essential resource for anyone working in the central areas of philosophy, and the starting point for future research in this fascinating ...

This volume is a wide-ranging examination of denial and ideological denialism. It offers a readable overview of the psychology and social science of bias, self-deception, and denial, and examines the role of ideological denialism in conflicts over science and public policy, politics, and culture.

"This book does nothing less than to set new standards in combining philosophical with political theology.

Bioethicists who seek to defend commercial transactions that intuitively seem exploitative, such as organ sales and commercial surrogacy, typically pair a liberal analysis of exploitation with a libertarian analysis of autonomy. In this paper, I argue that the liberal analysis of exploitation, which focuses primarily on two party transactions between individuals, occludes the structural dimensions of exploitation. This occlusion then paves the way for the transaction to be understood in terms of libertarian autonomy. I propose that a vulnerability analysis paired (...) with a multidimensional and relational theory of autonomy highlights the structural dimensions of exploitation and exposes the myth-making that underlies claims that these forms of exploitation are autonomy-enhancing. (shrink)

There remains no consensus among social scientists as to how to measure and understand forms of information deprivation such as misinformation. Machine learning and statistical analyses of information deprivation typically contain problematic operationalizations which are too often biased towards epistemic elites' conceptions that can undermine their empirical adequacy. A mature science of information deprivation should include considerable citizen involvement that is sensitive to the value-ladenness of information quality and that doing so may improve the predictive and explanatory power of extant (...) models. (shrink)

Ciencia y lógica de mundos posibles indaga en un aspecto negativo de la visión positivista de la historia del pensamiento. Según esta interpretación, determinante dentro del pensamiento contemporáneo, existe una oposición irredimible entre la metodología del conocimiento científico y la metafísica. El estudio de los supuestos ontológicos de la epistemología aristotélica y de la nueva metodología galileana evidencia, sin embargo, que históricamente la ciencia moderna no nace en oposición a la metafísica, sino que surge a partir de una concepción metafísica (...) determinada. Resulta imposible comprender a fondo el fenómeno de la revolución galileana sin tener en cuenta los aportes lógicos de pensadores medievales que tuvieron una actitud crítica frente a las implicaciones ontológicas de la epistemología aristotélica. Con el advenimiento del idealismo trascendental - a diferencia de Descartes, Leibniz o Newton - la filosofía se separa de la ciencia experimental. Esto se debe a que con Kant la filosofía se aleja de la postura filosófica de los origenes de la ciencia moderna, y retorna a una concepción de la naturaleza en cierto modo similar a la aristotélica. Así mismo, la interpretación propuesta en el manifiesto del Círculo de Viena con respecto a algunas de las revoluciones científicas de los siglos XIX y XX, supone que la ciencia moderna se ha desarrollado en la dirección señalada por la concepción metafísica del mundo que se encuentra en el origen de la revolución galileana. (shrink)