Emotionally arousing events may disrupt the ability to bind together different features of items to their context; this holds true both for spatial binding and temporal binding. Nonetheless, memory for emotional events may be enhanced in certain situations. A key factor that might explain the memory–emotion relation is represented by individual differences in cognition. The present study investigated temporal binding for neutral and negative events in a group of 50 undergraduate students, focusing on the role of individual differences in working (...) memory. Temporal binding was assessed with sorting accuracy of various pictorial scripted events, 24 h after encoding. Results showed that higher backward digit span predicted higher binding accuracy; importantly, this was qualified by the interaction with valence, such that higher backward digit span predicted better performance for negative, but not neutral, events. It is concluded that working memory facilitates binding of emotional events to their temporal context during encoding, creating a strong representation, and favouring later retrieval of such bound representations. (shrink)

Emotional content has complex effects on false memory. Under certain circumstances, emotional material may reduce the likelihood of false memory, a phenomenon that some consider related to it being...

Drawing on philosophy, law and political science, and on a wealth of practical experience delivering emergency medical services in conflict-ridden settings, Lepora and Goodin untangle the complexities surrounding compromise and complicity.

Medical complicity in torture is prohibited by international law and codes of professional ethics. But in the many countries in which torture is common, doctors frequently are expected to assist unethical acts that they are unable to prevent. Sometimes these doctors face a dilemma: they are asked to provide diagnoses or treatments that respond to genuine health needs but that also make further torture more likely or more effective. The duty to avoid complicity in torture then comes into conflict with (...) the doctor’s duty to care for patients. Sometimes the right thing for a doctor to do requires complicity in torture. Whether this is the case depends on: the expected consequences of the doctor’s actions; the wishes of the patient; and the extent of the doctor’s complicity with wrongdoing. Medical associations can support physicians who face this dilemma while maintaining a commitment to clear principles denouncing torture. (shrink)

This study offers a new interpretation of the poem of the founder of Western philosophy: Parmenides. It shows that there is more in his poem than the description of Being by means of negative adjectives such as ingenerated and immobile. His words ask his audience to question their habits, to modify their goals, to engage in new enterprises and to look with a critical eye at their previous attempts to get knowledge. It operates as a travel guide that leads the (...) audience on a journey that will educate them and help them to gradually become philosophically mature, to become true themselves, which can also be described as the encouragement to become Being. (shrink)

The current situation around COVID-19 portrays a threat to us in several ways: It imposes uncertainty, a lack of control and reminds us of our own mortality. People around the world have reacted to these threats in seemingly unrelated ways: From stockpiling yeast and toilet paper to favoring nationalist ideas or endorsing conspiratorial beliefs. According to the General Process Model of Threat and Defense the confrontation with a threat - a discrepant experience - makes humans react with both proximal and (...) distal threat responses. While the proximal response manifests in behavioral inhibition that leads to heightened anxious arousal and vigilance, distal responses seek to lower behavioral inhibition and the associated state of anxiety and vigilance through engaging in distal defenses. In the present research, we propose that the reactions to COVID-19 may represent distal defense strategies to the pandemic (in the form of environmental or group related worldview defenses) and therefore can be explained and forecasted by the model. Thus we hypothesized increased perceived COVID-19 threat perception to lead to a proximal threat response in the form of heightened behavioral inhibition. This, in return, should enhance the use of distal defenses (i.e.: several ingroup biases, system justification and conspiratorial beliefs) overlapping with the reactions observed as a response to COVID-19. This hypothesized mediated effect of increased perceived COVID-19 threat on distal defenses was tested in two pre-registered studies: In Study 1 (N = 358) results showed perceived COVID-19 threat to be related to behavioral inhibition and in turn to be associated with increased distal defenses (i.e., higher entitativity, control restoration motivation, passive party support). In Study 2 (N = 348) we manipulated COVID-19 threat salience and found results suggesting the distal defenses of system justification and conspiratorial beliefs to be mediated by the proximal threat response. The results of the present research hint towards a common mechanism through which the seemingly unrelated reactions to COVID-19 can be explained. The results might help to predict future behavior during the COVID-19 pandemic and design measures to counteract detrimental effects of the pandemic. (shrink)

The present paper focuses on a specific aspect of Michel Foucault’s interest in literature, addressing his study on the French poet and novelist Raymond Roussel. Published only few days before The Birth of the Clinic: An Archaeology of Medical Perception (1963), Death and the Labyrinth (1963) provides a philosophical reading of some Roussel’s writings, in a constant confrontation with the posthumous essay How I Wrote Certain of My Books (1935) in which Roussel explains his peculiar process of composition. Here, I (...) propose considering that Death and the Labyrinth offers not only a critical account on the relationship between philosophy and literature, but it also displays the significance of philosophy towards the study of literature. From this perspective, I will mainly focus on three themes – the death of the language; the repetition of the language; the duality of the language –, showing also that the first source of the Foucauldian further interest on the relationship between “words” and “things” has been Roussel’s oeuvre. (shrink)

This volume contains Gianfrancesco Pico's Life of his uncle Giovanni Pico and also Giovanni's Oration. Gianfrancesco's Life opens a collection that omits Giovanni's Conclusions but includes the speech that we - unlike Pico - know as an Oration on the Dignity of Man. He wrote the Oration to introduce the Conclusions, but his nephew's editorial decision cut the theses off from the speech that their author had connected with them. Several times in the Oration, the orator mentioned "theorems" to be (...) proposed in the Conclusions: he clearly saw the book and the speech as tools for the same task. Either Gianfrancesco missed his uncle's intentions, which seems unlikely, or he meant to seal off his other writings - including the Oration - from a book that he found embarrassing for himself and his relative and too risky to make public. This is the fact of the matter: Gianfrancesco left the Conclusions unpublished while publishing the Oration in a collection introduced by his Life. Both the speech and the biography are presented here, in this edition, in the same way - apart from the Conclusions: this reflects the situation in 1496 and respects Gianfrancesco's choice, even though his decision blocked understanding of the speech for many years. Today, with access to all the relevant texts in many versions, readers can move from one work to another as needed. (shrink)

There is a vast class of things that science has so far almost entirely neglected. They are central to the understanding of physical reality both at an everyday level and at the level of the most fundamental phenomena in physics, yet have traditionally been assumed to be impossible to incorporate into fundamental scientific explanations. They are facts not about what is--the actual--but about what could be: counterfactuals. According to physicist Chiara Marletto, laws about things being possible or impossible may (...) generate an alternative way of providing explanations. This fascinating, far-reaching approach holds promise for revolutionizing the way fundamental physics is formulated, but also for providing essential tools to face existing technological challenges, from delivering the next generation of information-processing devices, beyond the universal quantum computer, to designing AIs. Each chapter in the book delineates how an existing vexed open problem in science can be solved by this radically different approach; and it is augmented by short fictional stories that explicate the main point of the chapter. As Marletto demonstrates, contemplating what is possible can give us a more complete and hopeful picture of the physical world. (shrink)

Mathematics reinterpreted as political practice and not just as theory constitutes an extraordinary exercise in democracy: like democracy, it is based on a system of rules, creates groups, and works on relationships. Like democracy, mathematics widens but doesn't nullify things. By studying mathematics one can understand many things about truth. For instance, the fact that truths are shared and therefore the principles of authority do not exist; the fact that all truths are absolute but transient because they depend on the (...) set of definitions and on the surrounding conditions. Solving a mathematical problem is an exercise in democracy because those who do not accept error and do not strive to understand the world are not able to change or govern it. In her polemical pamphlet Chiara Valerio pieces together a parallel between mathematics and democracy, two fields that do not succumb to the dictatorship of urgency--Translated from back cover. (shrink)

Saggio storico-pedagogico costruito su scritti editi e inediti di Elena Marano, pedagogista, filantropa, scrittrice vissuta tra la il XIX e il XX secolo ad Adrano (Ct). Ancorato alla pedagogia tradizionale, il suo pensiero trae alimento da ideologi del Risorgimento (Mazzini e Gioberti), si confronta con studiosi e intellettuali coevi, si apre a forme di rigenerazione didattico-educative i cui temi precorrono la contemporaneità: riposizionamento morale per contrastare emergenza educativa, istruzione diffusa per abbattere disagio sociale e analfabetismo, formazione delle bambine per favorire (...) cittadinanza femminile e inserimento delle donne nella società, relazionalità produttiva e funzione pedagogica del lavoro per conseguire «quella legalità che è attributo dello Stato». Diversi gli aspetti dell'educazione – morale, intellettuale, civile...– che, avviando corresponsabilità educativa tra docente e studente, scuola e famiglia, costituiscono strumento di interazione tra le discipline e l'unità di pensiero, necessaria diade per la deduzione del vero. (shrink)

Throughout the present paper, I propose an analysis of René Magritte’s artwork Les mots et les images (La Révolution surréaliste, 1929) in connection with a reflection on the associated theories he formulated in the handout for his London lecture (1937). Read in reference to selected writings (and in erratic observation with other artworks of his oeuvre), the eighteen propositions of Les mots et les images, along with their development in the 1937 document, might help at investigating the aesthetic principles that (...) guide and characterise Magritte’s reflection around language. In this same regard, in the last part of my article I will focus on Michel Foucault’s Ceci n’est pas une pipe (1973) and, particularly, on the distinction between resemblance (ressemblance) and similitude (similitude). These last remarks, I argue, offer the opportunity not only to think about the way in which images and words are related to each other in Magritte’s works, but also to inves- tigate the vital issue of language, which has occupied a crucial place within French thought. (shrink)

Il volume comprede una serie di saggi sui passi più significativi del commento di Alessandro di Afrodisia al IV libro dei Topici di Aristotele. In particolare, i saggi sono dedicati ai seguenti tre argomenti, su cui Alessandro espone tesi estremamente interessanti. Il primo tratta la dialettica, cioè l'argomento dei Topici; segue poi il genere, che costituisce l'argomento del IL libro in particolare; infine l'anima, le discussioni intorno alla quale costituiscono per il commentatore un esempio privilegiato per illustare i "luoghi" dialettici (...) via via discussi."--Page 2 of cover. (shrink)

Diese Ausgabe bietet erstmals einen Schlüsseltext für die Reformation der Metaphysik in der Philosophie der Renaissance in deutscher Übersetzung. Der lateinische Text ist beigegeben. Die ausführliche Einleitung und ein sorgfältiger Kommentar erschließen die richtunggebenden Pointen, die Pico mit dieser Schrift gesetzt hat.

t. 1. Scripta in editione Basilensi anno 1573 collecta. 2 v.

What are the most detailed descriptions under which subjects intend to perform bodily actions? According to Pacherie (2006), these descriptions may be found by looking into motor representations—action representations in the brain that determine the movements to be performed. Specifically, for any motor representation guiding an action, its subject has an M‐intention representing that action in as much detail. I show that some M‐intentions breach the constraints that intentions should meet. I then identify a set of intentions—motor intentions—that represent actions (...) in as much detail as some motor representations while meeting the constraints that intentions should meet. (shrink)

We develop an account of how mutually inconsistent models of the same target system can provide coherent information about the system. Our account makes use of ideas from the debate surrounding rob...

Boredom, in cinema as well as in our everyday experience, is usually associated with a generalised loss of meaning or interest. Accordingly, boredom is often perceived as that which ought to be avo...

After initially emerging in China, the coronavirus outbreak has advanced rapidly. The World Health Organization has recently declared it a pandemic, with Europe becoming its new epicentre. Italy has so far been the most severely hit European country and demand for critical care in the northern region currently exceeds its supply. This raises significant ethical concerns, among which is the allocation of scarce resources. Professionals are considering the prioritisation of patients most likely to survive over those with remote chances, and (...) this news has triggered an intense debate about the right of every individual to access healthcare. The proposed analysis suggests that the national emergency framework in which prioritisation criteria are currently enforced should not lead us to perceive scarce resources allocation as something new. From an ethical perspective, the novelty of the current emergency is not grounded in the devastating effects of scarce resources allocation, which is rife in recent and present clinical practice. Rather, it has to do with the extraordinarily high number of people who find themselves personally affected by the implications of scarce resources allocation and who suddenly realise that the principle of ‘equals should be treated equally’ may no longer be applicable. Along with the need to allocate appropriate additional financial resources to support the healthcare system, and thus to mitigate the scarcity of resources, the analysis insists on the relevance of a medical ethics perspective that does not place the burden of care and choice solely on physicians. (shrink)

In the philosophy of science and epistemology literature, robustness analysis has become an umbrella term that refers to a variety of strategies. One of the main purposes of this paper is to argue that different strategies rely on different criteria for justifications. More specifically, I will claim that: i) robustness analysis differs from de-idealization even though the two concepts have often been conflated in the literature; ii) the comparison of different model frameworks requires different justifications than the comparison of models (...) that differ only for the assumption under test; iii) the replacement of specific assumptions with different ones can encounter specific difficulties in scientific practice. These claims will be supported by a case study in population ecology and a case study in geographical economics. (shrink)

Epicurus’ original version of atomism takes atoms to be physically indivisible but not completely unanalysable: each atom contains a finite number of minima. This paper explores the nature of the minima by focusing on a specific question: in which sense are the minima minimal? I do so by investigating the notions of parthood and divisibility into parts that are at play in paragraphs 56–59 of the Letter to Herodotus, where the theory of minima is introduced. By focusing on the analogy (...) (noticed by Francesco Verde) between Epicurean minima and Aristotelian limits, I argue that the minima should be understood as the minimal realiser of the atom’s physical functions. This allows me to keep together two very plausible but apparently incompatible claims: (i) the minima are supposed to block the paradoxes of theoretical divisibility, but (ii) their existence and their indivisibility can only be justified in physical (rather than geometrical) terms. (shrink)

The exponential accumulation, processing and accrual of big data in healthcare are only possible through an equally rapidly evolving field of big data analytics. The latter offers the capacity to rationalize, understand and use big data to serve many different purposes, from improved services modelling to prediction of treatment outcomes, to greater patient and disease stratification. In the area of infectious diseases, the application of big data analytics has introduced a number of changes in the information accumulation models. These are (...) discussed by comparing the traditional and new models of data accumulation. Big data analytics is fast becoming a crucial component for the modelling of transmission—aiding infection control measures and policies—emergency response analyses required during local or international outbreaks. However, the application of big data analytics in infectious diseases is coupled with a number of ethical impacts. Four key areas are discussed in this paper: automation and algorithmic reliance impacting freedom of choice, big data analytics complexity impacting informed consent, reliance on profiling impacting individual and group identities and justice/fair access and increased surveillance and population intervention capabilities impacting behavioural norms and practices. Furthermore, the extension of big data analytics to include information derived from personal devices, such as mobile phones and wearables as part of infectious disease frameworks in the near future and their potential ethical impacts are discussed. Considered together, the need for a constructive and transparent inclusion of ethical questioning in this rapidly evolving field becomes an increasing necessity in order to provide a moral foundation for the societal acceptance and responsible development of the technological advancement. (shrink)

Compromise arises in contexts where irreconcilable claims must nonetheless somehow be resolved. Ordinary people in everyday life, politicians and artists, doctors engaging in research, humanitarian workers providing aid in the midst of war – all of them will have faced situations where compromise appeared to be the only reasonable option, and yet will have felt that there was nevertheless something deeply wrong with it. The aim of this paper is to help make sense of that sentiment. The focus of this (...) paper will be on some aspects of the morality of compromise. Its lynchpin will be to construe compromise as a joint action, in particular, a joint wrongdoing – taking part in, and sharing responsibility for, the doing of things that are wrong from the point of view of those who are the parties to the compromise. The question of ‘what is wrong with compromise?’ is thus recast as a question of ‘what is my part in the wrongs being done as part of the compromise?’ It is tempting to suppose that a compromise serves to dilute personal responsibility, parsing it out among parties to the compromise. Viewing a compromise as a joint action, in contrast, will help us to see how a compromise actually increases responsibility among parties to it. They are now jointly collaborating in some action that each of them sees as wrong, at least in part (albeit in differing parts). Discussions of compromise traditionally prioritize the inter-personal aspect – compromise, in the transitive form of ‘compromising with’ someone. But I argue that the intransitive form – ‘compromise of’ – deserves pride of place. The reason for prioritizing the intransitive ‘compromise of’ is simple: that is what is involved in the intra-personal calculation that must, of necessity, go on inside one's own head in the process of deciding whether or not to agree to a 'compromise with' someone else. In this paper I shall concentrate specifically on compromises of principles, or (more precisely) on ‘matters of principled concern to the compromising parties’. Not only is that the most troubling and morally problematic sort of compromise, it is also logically the most central case. I demonstrate that that is so by shifting the focus from inter-personal compromise to the more fundamental intra-personal process underlying it – the compromise we are involved in when adjudicating among our own conflicting values, to decide whether or not to agree to a compromise of the inter-personal sort. This is the subject of the first section of the paper below. Compromise involves resolving conflicts of principles through mutual concessions that are accepted and undertaken by all parties. Doing so may be on-balance desirable, not only from some larger perspective (of social peace, or whatever) but also from each party's own perspective. Nevertheless, from each party's perspective, compromise necessarily involves interacting with, and sometimes contributing to, wrongdoing. Morally, something is lost, even if more is gained on balance. (shrink)

RNA modifications have recently emerged as an important regulatory layer of gene expression. The most prevalent and reversible modification on messenger RNA (mRNA), N6‐methyladenosine, regulates most steps of RNA metabolism and its dysregulation has been associated with numerous diseases. Other modifications such as 5‐methylcytosine and N1‐methyladenosine have also been detected on mRNA but their abundance is lower and still debated. Adenosine to inosine RNA editing is widespread on coding and non‐coding RNA and can alter mRNA decoding as well as protect (...) against autoimmune diseases. 2′‐O‐methylation of the ribose and pseudouridine are widespread on ribosomal and transfer RNA and contribute to proper RNA folding and stability. While the understanding of the individual role of RNA modifications has now reached an unprecedented stage, still little is known about their interplay in the control of gene expression. In this review we discuss the examples where such interplay has been observed and speculate that with the progress of mapping technologies more of those will rapidly accumulate. (shrink)

Friedrich Albert Lange is usually regarded as a representative of physiological neo-Kantianism or as a forerunner of the Marburg school of neo-Kantianism. In this paper I try to reconstruct Lange’s theory of values to argue that his philosophy is better framed as an intermediate point in the development of the two-world theory (facts/values) between Hermann Lotze and Southwestern neo-Kantianism.

The Sārasaṅgaha is a Pāli text of XIIth–XIIIth century by the Sinhalese monk Siddhattha Thera. Its themes include the aspiration to become a Buddha, shrines, meditation, theories on rain, wind, gender and more. The main body consists of citations from the Nikāyas, the Jātakas, the Visuddhimagga and above all, from commentarial literature. By analysing the way the Sārasaṅgaha refers to and establishes a dialogue with the quoted works, this paper promotes a new assessment of the cultural and textual tendencies that (...) influenced the development of Buddhist literature especially in the Middle Ages. In particular, the analysis of this text and the quotations of which it is composed reveals the importance of commentarial literature, a literary genre that only recently has attracted the attention of Pāli scholars. (shrink)

: Autonomous driving systems promise important changes for future of transport, primarily through the reduction of road accidents. However, ethical concerns, in particular, two central issues, will be key to their successful development. First, situations of risk that involve inevitable harm to passengers and/or bystanders, in which some individuals must be sacrificed for the benefit of others. Secondly, and identification responsible parties and liabilities in the event of an accident. Our work addresses the first of these ethical problems. We are (...) interested in investigating how humans respond to critical situations and what reactions they consider to be morally right or at least preferable to others. Our experimental approach relies on the trolley dilemma and knowledge gained from previous research on this. More specifically, our main purpose was to test the difference between what human drivers actually decide to do in an emergency situations whilst driving a realistic simulator and the moral choices they make when they pause to consider what they would do in the same situation and to better understand why these choices may differs. Keywords: Self-driving Cars; Trolley Problem; Moral Choices; Moral Responsibility; Virtual Reality Dilemmi morali nelle automobili a guida autonoma Riassunto: I sistemi di guida autonomi promettono importanti cambiamenti per il futuro dei trasporti, principalmente attraverso la riduzione degli incidenti stradali. Tuttavia, vi sono preoccupazioni etiche, in particolare due questioni centrali, fondamentali per il loro sviluppo. In primo luogo, le situazioni di rischio che comportano inevitabili danni ai passeggeri e/o ai pedoni, ovvero situazioni in cui alcune persone devono essere sacrificate a beneficio di altri. In secondo luogo, l’identificazione delle parti responsabili in caso di incidente. Il nostro lavoro affronta il primo di questi problemi etici. Siamo interessati a studiare come gli umani rispondono a situazioni critiche e quali reazioni considerano moralmente giuste o almeno preferibili. Il nostro approccio sperimentale si basa sul trolley problem e sulle conoscenze acquisite da precedenti ricerche su questo ambito. Più specificamente, il nostro scopo principale è quello di testare la differenza tra ciò che i conducenti umani decidono effettivamente di fare in una situazione di emergenza, mentre guidano un simulatore realistico, e le scelte morali che compiono se posti nella stessa situazione e hanno la possibilità di decidere senza limiti di tempo. Lo scopo è inoltre comprendere come e perché queste scelte possono differire. Parole chiave: Automobili a guida autonoma; Trolley problem; Scelte morali; Responsabilità morale, Realtà virtuale. (shrink)