A review with commentary on Mark A. Bedau and Emily C. Parke (eds): The Ethics of Protocells: Moral and Social Implications of Creating Life in the Laboratory (Basic Bioethics series) MIT Press, Cambridge,MA, 2009, 365 pp, ISBN 978-0-262-01262-1, ISBN 978-0-262-51269-5.

Bringing together the latest scientific advances and some of the most enduring subtle philosophical puzzles and problems, this book collects original historical and contemporary sources to explore the wide range of issues surrounding the nature of life. Selections ranging from Aristotle and Descartes to Sagan and Dawkins are organised around four broad themes covering classical discussions of life, the origins and extent of natural life, contemporary artificial life creations and the definition and meaning of 'life' in its most general form. (...) Each section is preceded by an extensive introduction connecting the various ideas discussed in individual chapters and providing helpful background material for understanding them. With its interdisciplinary perspective, this fascinating collection is essential reading for scientists and philosophers interested in astrobiology, synthetic biology and the philosophy of life. (shrink)

In this provocative study, Bedau demonstrates the usefulness of "casuistry," or "the method of cases" in arriving at moral decisions. He examines well-known cases, including the aftermath of the sinking of the William Brown in 1841, that compel us to consider questions about who ought to survive when not all can. By doing so, we learn something about how we actually reason concerning such life and death situations, as well as about how we ought to reason if we wish both (...) to be consistent and to properly respect human life. Bedau's elegant book will be a valuable resource for students, philosophers, and general readers. (shrink)

An innocent form of emergence—what I call "weak emergence"—is now a commonplace in a thriving interdisciplinary nexus of scientific activity—sometimes called the "sciences of complexity"—that include connectionist modelling, non-linear dynamics (popularly known as "chaos" theory), and artificial life.1 After defining it, illustrating it in two contexts, and reviewing the available evidence, I conclude that the scientific and philosophical prospects for weak emergence are bright.

Weak emergence is the view that a system’s macro properties can be explained by its micro properties but only in an especially complicated way. This paper explains a version of weak emergence based on the notion of explanatory incompressibility and “crawling the causal web.” Then it examines three reasons why weak emergence might be thought to be just in the mind. The first reason is based on contrasting mere epistemological emergence with a form of ontological emergence that involves irreducible downward (...) causation. The second reason is based on the idea that attributions of emergence are always a reflection of our ignorance of non-emergent explanations. The third reason is based on the charge that complex explanations are anthropocentric. Rather than being just in the mind, weak emergence is seen to involve a distinctive kind of complex, macro-pattern in the mind-independent objective micro-causal structure that exists in nature. The paper ends by addressing two further questions. One concerns whether weak emergence applies only or mainly to computer simulations and computational systems. The other concerns the respect in which weak emergence is dynamic rather than static. (shrink)

In modern times the idea of the objectivity of law has been undermined by skepticism about legal institutions, disbelief in ideals of unbiased evaluation, and a conviction that language is indeterminate. Greenawalt here considers the validity of such skepticism, examining such questions as: whether the law as it exists provides determinate answers to legal problems; whether the law should treat people in an "objective way," according to abstract rules, general categories, and external consequences; and how far the law is anchored (...) in something external to itself, such as social morality, political justice, or economic efficiency. In the process he illuminates the development of jurisprudence in the English-speaking world over the last fifty years, assessing the contributions of many important movements. (shrink)

Artificial life (also known as “ALife”) is a broad, interdisciplinary endeavor that studies life and life-like processes through simulation and synthesis. The goals of this activity include modelling and even creating life and life-like systems, as well as developing practical applications using intuitions and methods taken from living systems. Artificial life both illuminates traditional philosophical questions and raises new philosophical questions. Since both artificial life and philosophy investigate the essential nature of certain fundamental aspects of reality like life and adaptation, (...) artificial life offers philosophy a new perspective on these phenomena. This chapter provides an introduction to current research in artificial life and explains its philosophical implications. (shrink)

We can readily identify goal-directed systems and distinguish them from non-goal-directed systems. A woodpecker hunting for grubs is the first, a pendulum returning to rest is the second. But what is it to be a goal-directed system? Perhaps the dominant answer to this question, inspired by systems theories such as cybernetics, is that goal-directed systems are distinguished by their tendency to seek, aim at, or maintain some more-or-less easily identifiable goal. Cybernetics and the like would hold that physical systems subject (...) only to physical laws can exhibit such behavior. If sound, this systems approach to teleology would unify a diverse range of goal-directed phenomena and neatly side-step many traditional bogey-men of teleology, such as anthropomorphism and future causation. Goal-directed phenomena would be a normal feature of the natural causal world that could be described in purely descriptive and quantitative terms, and receive ordinary causal explanations. Thus, the systems approach promises to provide a naturalistic-cum-descriptive account of teleology suitable for use in naturalistic accounts of other phenomena, including the intentionality of mental states and even self-consciousness. (shrink)

This paper describes and defends the view that minimal chemical life essentially involves the chemical integration of three chemical functionalities: containment, metabolism, and program (Rasmussen et al. in Protocells: bridging nonliving and living matter, 2009a ). This view is illustrated and explained with the help of CMP and Rasmussen diagrams (Rasmussen et al. In: Rasmussen et al. (eds.) in Protocells: bridging nonliving and living matter, 71–100, 2009b ), both of which represent the key chemical functional dependencies among containment, metabolism, and (...) program. The CMP model of minimal chemical life gains some support from the broad view of life as open-ended evolution, which I have defended elsewhere (Bedau in The philosophy of artificial life, 1996 ; Bedau in Artificial Life, 4:125–140, 1998 ). Further support comes from the natural way the CMP model resolves the puzzle about whether life is a matter of degree. (shrink)

This paper examines hart's model (1967) of the retributive theory. section i criticizes the model for not answering all the main questions to which a theory of punishment should be addressed, as hart alleges it does. section ii criticizes the model for its omission of the concept of desert. section iii criticizes attempts by card (1973) and by von hirsch (1976) to provide new ways of proportioning punitive severity to criminal injury. section iv discusses the idea of retribution in justifying (...) aim and criticizes the theory of fingarette (1977). the conclusion is that the new retributivists have not solved the problems inherent to older versions of the theory. (shrink)

This paper investigates how environmental structure, given the innate properties of a population, affects the degree to which this population can adapt to the environment. The model we explore involves simple agents in a 2-d world which can sense a local food distribution and, as specified by their genomes, move to a new location and ingest the food there. Adaptation in this model consists of improving the genomic sensorimotor mapping so as to maximally exploit the environmental resources. We vary environmental (...) structure to see its specific effect on adaptive success. In our investigation, two properties of environmental structure, conditioned by the sensorimotor capacities of the agents, have emerged as significant factors in determining adaptive success: (1) the information content of the environment which quantifies the diversity of conditions sensed, and (2) the expected utility for optimal action. These correspond to the syntactic and pragmatic aspects of environmental information, respectively. We find that the ratio of expected utility to information content predicts adaptive success measured by population gain and information content alone predicts the fraction of ideal utility achieved. These quantitative methods and specific conclusions should aid in understanding the effects of environmental structure on evolutionary adaptation in a wide range of evolving systems, both artificial and natural. (shrink)

Weak emergence has been offered as an explication of the ubiquitous notion of emergence used in complexity science (Bedau 1997). After outlining the problem of emergence and comparing weak emergence with the two other main objectivist approaches to emergence, this paper explains a version of weak emergence and illustrates it with cellular automata. Then it explains the sort of downward causation and explanatory autonomy involved in weak emergence.

The robust behavior of the patent citation network is a complex target of recent bottom-up models in science. This paper investigates the purpose and testing of three especially simple bottom-up models of the citation count distribution observed in the patent citation network. The complex causal webs in the models generate weakly emergent patterns of behavior, and this explains both the need for empirical observation of computer simulations of the models and the epistemic harmlessness of the resulting epistemic opacity.

What makes a cell? How are cells able to replicate themselves in a stable manner? How did cellular life emerge on our planet? The answer to these fundamental questions lies at the base of biology. Cellular life is the basic unit of living organization and defines the presence of a stable information reservoir connected through the external world by a well-defined boundary. Inside the cell, chains of computations and chemical reactions take place, sustained by self-assembled molecular machines. At the cell (...) membrane, the environment and the cell communicate with each other through proteins that are able to detect small concentration changes and send the appropriate signals. But modern cells are very sophisticated entities and extracting the logic of cell organization from them is a gigantic effort. In order to answer these questions, we need to look at cells in a more basic level: a reduction of complexity is needed. Protocells, roughly defined as the simplest instances of autonomous cell-like structures, have been a matter of exploration for decades. Although most of the original work in this area was largely theoretical, the end of the twentieth century was marked by very active experimental research on minimal cells. One approach has been the top-down strategy, where living organisms (the simplest life forms) are being selectively modified to reduce their genome complexity. Such a minimal genome would be the smallest one able to sustain reproduction and growth under a given set of external constraints (mainly available molecules). The second approach is the bottom-up one, very much in the tradition of research into the origins of life. Under this approach, extremely simple life forms are built from basic chemical components, including lipids and a basic.. (shrink)

To surmount the notorious difficulties of defining life, we should evaluate theories of life not by whether they provide necessary and sufficient conditions for our current preconceptions about life but by how well they explain living phenomena and how satisfactorily they resolve puzzles about life. On these grounds, the theory of life as supple adaptation (Bedau 1996) gets support from its natural and compelling resolutions of the following four puzzles: (1) How are different forms of life at different levels of (...) the vital hierarchy related? (2) Is there a continuum between life and non-life? (3) Does life essentially concern a living entity’s material composition or its form? (4) Are life and mind intrinsically connected? (shrink)

This paper describes and defends the view that minimal chemical life essentially involves the chemical integration of three chemical functionalities: containment, metabolism, and program. This view is illustrated and explained with the help of CMP and Rasmussen diagrams in Protocells: bridging nonliving and living matter, 71–100, 2009b), both of which represent the key chemical functional dependencies among containment, metabolism, and program. The CMP model of minimal chemical life gains some support from the broad view of life as open-ended evolution, which (...) I have defended elsewhere. Further support comes from the natural way the CMP model resolves the puzzle about whether life is a matter of degree. (shrink)

Top-down synthetic biology makes partly synthetic cells by redesigning simple natural forms of life, and bottom-up synthetic biology aims to make fully synthetic cells using only entirely nonliving components. Within synthetic biology the notions of complexity and emergence are quite controversial, but the imprecision of key notions makes the discussion inconclusive. I employ a precise notion of weak emergent property, which is a robust characteristic of the behavior of complex bottom-up causal webs, where a complex causal web is one that (...) is incompressible and its behavior cannot be derived except by crawling through all of the gory details of the interactions in the web. The central thesis of this article is that synthetic biology centrally is the activity of engineering the desired weak emergent properties of synthetic cells. Synthetic biology has many different ways to engineer desired weak emergent properties of synthetic cells, including Edisonian trial and error, standardized parts, refactoring, and reprogramming synthetic genomes. The article ends by noting two philosophical consequences of engineering weak emergence. One is epistemological: synthesis is crucial for discovering weak emergent properties. The other is metaphysical: simple life forms are nothing but complex chemical mechanisms. (shrink)

Weak emergence has been offered as an explication of the ubiquitous notion of emergence used m complexity science After outlining the problem of emergence and comparing weak emergence with the two other weak objectivist approaches to emergence, the paper explains a version of weak emergence and illustrates at with cellular automata Then it explains the sort of downward causation and explanatory autonomy involved m weak emergence.

This chapter contains section titled: The Fascination of Life The Phenomena of Life Puzzles about Life Accounts of Life The Problem of Understanding Life References Further Reading.

The prelims comprise: The Roots of Artificial Life The Methodology of Artificial Life Emergence Adaptationism Evolutionary Progress The Nature of Life Strong Artificial Life Philosophical Methodology.

Recent discussions of civil disobedience show the world of scholarship and public affairs in disarray. Not only is there considerable disagreement over how civil disobedience is to be justified, there is hardly less disagreement over what civil disobedience is. Can it be violent, or must it be nonviolent, in intention and in outcome? Can civil disorder be a special case of mass civil disobedience? Must civil disobedience proceed within the framework of the existing politico-legal system or may it be revolutionary (...) in intention? Could it be anarchistic? Should the authorities endeavor to prosecute and punish the civil disobedient as though he were a common criminal? Is disobedience which results in no punishment of the disobedient not civil disobedience after all? Because of disagreements over the answers to these questions, the description of an act as an act of civil disobedience is likely to be ambiguous and controversial not only for the general public and the government but even in some cases for the protesters themselves. Confusion rooted in honest misunderstanding is compounded by bad faith, by basic disagreements over the ideal and the actual relations between the individual and the state, and by obscurity in the facts surrounding the intentions of the protesters and the consequences of their acts. (shrink)