Dominant views of personal identity in philosophy take some kind of psychological continuity or connectedness over time to be criterial for the identity of a person over time. Such views assign psychological states, particularly those necessary for narrative memory of some kind, special importance in thinking about the nature of persons. The extended mind thesis, which has generated much recent discussion in the philosophy of mind and cognitive science, holds that a person’s psychological states can physically extend beyond that person’s (...) body. Since “person” is a term of both metaphysical and moral significance, and discussions of both extended minds and personal identity have often focused on memory, this article explores the relevance of extended cognition for the identity of persons with special attention to neuroethics and memory. (shrink)

Abstract:Non-anthropocentric approaches to environmental ethics face problems that cannot be resolved within a holistic framework of natural value since such frameworks posit abstract and general properties as the bearers of intrinsic value and thus ignore the moral claims of individual organisms. Two paradigm examples of such approaches, Aldo Leopold's Land Ethic and Arne Neass' Deep Ecology suffer from this problem. Christine Korsgaard's argument for the conceptual separation of intrinsic and instrumental valuing, however, serves as a strong theoretical grounding for a (...) reconceptualization of the value of nature, which can best be described as an enlightened anthropocentrism, while preserving the spirit of Leopold's and Naess' proposals. (shrink)

David Lewis cautions that although a no-collapse interpretation of quantum mechanics entails immortality for trans-world selves, the nature of the branching leaves us crippled, lonely, deathly ill, and mentally infirm, meaning that immortal life, on such terms, amounts to an existence in eternal torment. This paper argues that the problem Lewis points to is in fact one of individuation and that a synthesis of Lewis’ own notion of perdurance and Robert Nozick’s closest continuer theory, when cast in the mould of (...) a deterministic multiverse, individuates trans-world selves in such a way as to allow to prune the infinitesimal expectation of a miserable eternal existence from the histories of most trans-world agents. Thus, contrary to Lewis’ warning that if personal identity is a trans-world notion, then we should all shake in our shoes, this paper argues that even if we are trans-world selves, we almost certainly have nothing to worry about. (shrink)

Arne Neass’ Ecosophy and the Stoic attitude towards environmental ethics are often believed to be incompatible primarily because the first is often understood as championing an ecocentric standpoint while the latter espouses an egocentric (as well as an anthropocentric) view. This paper argues that such incompatibility is rooted in a misunderstanding of both Ecosophy and Stoicism. Moreover, the paper argues that a synthesis of both the Ecosophical and Stoic approaches to environmental concerns results in a robust and satisfying attitude toward (...) the environment, namely an enlightened self-interest, which not only guards our fragile environment from abuse, but also provides self-interested reasons and motivations for the protection of our natural surroundings. (shrink)

This Dissertation argues for a care-centrically grounded account of relational personhood and widely realized diachronic personal identity. The moral distinction between persons and non-persons is arguably one of the most salient ethical lines we can draw since many of our most fundamental rights are delineated via the bounds of personhood. The problem with drawing such morally salient lines is that the orthodox, rationalistic definition of personhood, which is widespread within philosophical, medical, and colloquial spheres, excludes, and thereby de-personifies, a large (...) number and a great variety of human beings such as neonates, young children, the elderly who suffer from dementia, individuals with severe cognitive disabilities, and patients in vegetative states. The reconceptualization of personhood necessary for a more inclusive definition ought to originate with an appropriate moral grounding. To this end, this Dissertation grounds the notion of personhood in the care ethical sphere, thereby emphasizing the role of care relations in the maintenance of the moral consideration of vulnerable individuals. This Dissertation argues that grounding the concept of a person in care relations entails a relational account of personhood, which, along with the insights of the Extended Mind and Social Manifestation Theses, leads to an extended and externalized understanding of diachronic identity, which allows fragile people to be held in their personal identities even if they themselves lack the capacities usually associated with moral personhood. As we trace a person’s identity through time, we track the various relational properties, which constitute personal narratives and thus act as a glue that binds such dynamic and often unique properties into stable, trackable narratives. Since care relations are morally relevant on a care-centric account of personhood, what is lost in cases where such care relating ceases is not merely of sentimental value, but of great moral importance as well. Morally meaningful care relations are not replaceable, and, by extension, neither are the narratives that are constituted by such unique and irreplaceable instances of relating. This Dissertation argues that the constitutive care relational nature of personal narratives makes such narratives irreplaceable and is precisely what makes persons so morally precious. (shrink)

David Lewis’ contemplations regarding divine foreknowledge and free will, along with some of his other more substantial work on modal realism and his counterpart theory can serve as a springboard to a novel solution to the foreknowledge and metaphysical freedom puzzle, namely a proposal that genuine metaphysical freedom is compatible with determinism, which is quite different from the usual compatibilist focus on the compatibility between determinism and moral responsibility. This paper argues that while Lewis opens the doors to such a (...) possibility, in order to fully elucidate a genuinely metaphysical compatibilist account, Lewis’ own counterpart theory must be abandoned in favour of an account of trans-world identity that is theoretically framed by a modified version of Robert Nozick’s closest continuer theory. (shrink)

Unresolved disagreements on issues of access, censorship, and privacy within the information profession can be dangerous when entrepreneurial interests outweigh the public good and as corporations anticipate financial gain from placing limitations on information retrieval and use. The information profession can benefit from a grounding of its core values in a robust moral framework that can coherently place demands on interested parties. We argue that grounding the core values of privacy and ubiquitous access to information in a needs-based theory of (...) rights is most suitable within the unique context of the information profession. (shrink)

While the Philosophy for Children method has been adopted within classrooms by individual teachers and into some school systems by schoolboards, public and school libraries, the ideal users of this sort of programming, have been slow to recognise the benefits of this didactic methodology. This is particularly surprising given that the P4C method integrates perfectly with traditional story-time orientated programming. Not only is the integration of P4C into story-time sessions virtually seamless, but it might also help reinvigorate a well-established feature (...) of library programming with an aim to develop 21st-century information literacy competencies. This paper examines the case for the P4C method, explains the process of integration of the P4C method with traditional story-time, and highlights the potential benefits of incorporating Philosophy for Children in public and school library programming. (shrink)

This chapter argues that as the online informational landscape continues to expand, shortcuts to source credibility evaluation, in particular the revered checklist approach, falls short of its intended goal, and this method cannot replace the acquisition of a more formally acquired and comprehensive information literacy skill set. By examining the current standard of checklist criteria, the authors identify problems with this approach. Such shortcuts are not necessarily effective for online source credibility assessment, and the authors contend that in cases of (...) high-stakes informational needs, they cannot adequately replace the expertise of information professionals, nor displace the need for proper and continuous information literacy education. (shrink)

This paper argues that while the classical, essentialist conception of identity is appealing due to its simplicity, it does not adequately capture the complexity of professional or individual identity. The appeal to essentialism in librarianship contributes to some serious problems for the profession, such as exclusion and homogeneity in the workplace, high attrition rates of minority librarians, exploitation and alienation of an underrepresented workforce, as well as stereotyping. This paper examines the theoretical landscape with regard to the identity question and (...) proposes a more fitting alternative to essentialism, namely the relational conception of identity, and engages in a philosophical argument for the adoption of the relational account as a theoretical grounding for an understanding of the complex, fluid, and emergent nature of librarian identity within our dynamic profession. (shrink)

This essay is an attempt to propose an outline of a new respiratory animal philosophy. Based on an analysis of the forgetting of breath in Western philosophy, it aims to gesture towards a future, breathful and compassionate world of co-sharing and co-breathing. In the first part, the basic features of forgetting of breath are explained based on David Abram’s work in respiratory ecophilosophy. This part also introduces an important contribution to modern philosophy by Ludwig Klages. The second part is dedicated (...) to reflections on what I understand as an unfortunate transition from soul and pneuma to spirit and Geist. Based on these analyses, I proceed towards an idiosyncratic thought on the nocturnal mystery of pneuma, with references to ancient Upanishadic and 20th-century phenomenological Levinasian thought. Based on these teachings, I argue that, at the bottom of her existence, the subject is a lung partaking in an immense external lung (Merleau-Ponty). In the fourth part of the essay, I extend my reflections toward comparative animal respiratory phenomenology and argue for the immense compassion for all our fellow breathing beings. Finally, in the concluding, fifth part of this essay, I am arguing for a future biocentric and breathful environment, signifying and bringing a new compassionate-respiratory alliance into the world. (shrink)

This paper argues, against the prevailing view, that consent to privacy policies that regular internet users usually give is largely unproblematic from the moral point of view. To substantiate this claim, we rely on the idea of the right not to know (RNTK), as developed by bioethicists. Defenders of the RNTK in bioethical literature on informed consent claim that patients generally have the right to refuse medically relevant information. In this article we extend the application of the RNTK to online (...) privacy. We then argue that if internet users can be thought of as exercising their RNTK before consenting to privacy policies, their consent ought to be considered free of the standard charges leveled against it by critics. (shrink)

The immune system does not just fight pathogens but also engages in interactions with beneficial microbes and non-immune cells of the body to harmonize their behavior by means of cytokines, antibodies and effector cells (Dinarello, 2007; Moticka, 2015, pp. 217e226, 261e267). However, the importance of these “housekeeping” functions has not been fully appreciated (Cohen, 2000). In his new book Immunity: The Evolution of an Idea Alfred I. Tauber traces the history of fundamental ideas in immunology and refers to recent advances (...) in the field to overturn the notion that immunity is the ability of an autonomous organism to protect itself against pathogens. Indeed, as suggested by the author, the autonomy of the organism is illusive because individuals develop as holobionts: functionally integrated multispecies consortia (p. 98). Similarly, he suggests that pathogenicity also emerges from the lack of subordination of a microbe to social welfare of the holobiont rather than from context-independent properties of this organism (pp. 165, 181). Emphasizing the contextual character of the parasite and the host, Tauber redefines immunity as an active process of coordination of a cellular ecosystem, which allows this collective to navigate through challenges of the environment and to face demands of the communal living (pp. 10e16). From this point of view, the failure to modulate intercellular interactions by the immune system entails mitigating immunity and impairing resistance to infection and disease (pp. 103e104). Immunity is a groundbreaking work establishing a new framework for understanding the function and activity of the immune system. Its value also lies in the fact that it serves as an important stepping-stone towards an integrated philosophical, ecological and immunological study of our embedment in the microbial world. (shrink)

The following article challenges the traditional reading of the Rural Dionysia scene in Aristophanes’ Acharnians. It is often assumed that the text contains a reference to an animal sacrifice, which is arguably absent from this comedy. Moreover, the vast majority of scholars claim that the lines 244 ff. were uttered after the procession of worshippers reached the altar in the orchestra. However, as I argue, these verses were most probably spoken by the characters in front of the door of the (...) comic hero’s house and only subsequently did the procession form and move towards the altar. (shrink)

The history of relationship between faith and reason is marked by four models of the interaction between science and theology proposed by Ian G. Barbour: conflict, independence, dialogue and integration. Even if nineteenth-century positivism is still present in many scientists’ minds, philosophy of science eventually managed to overcome it in the 1960s. A mutual distrust between faith and reason started to disappear. In this context Fr. Michał Heller presented a project of a new discipline – the theology of science which (...) would look at the boundaries of the natural sciences from the theological point of view. According to Fr. Wojciech Giertych the adequate model of relationship between faith and reason can be based theologically on Chalcedonian Christology of Jesus’ two natures. Since reason and faith come together unconfusedly and inseparably in a human being, a mutual dialogue and even integration between theology and science is by all means possible. (shrink)

The subject of this article in an analysis of the globalisation process in economic and social areas. The author describes the main spheres of globalisation such as economic and political integration, the declining role of nation states, cultural homogenisation and the increasing significance of transnational corporations. The advantages and disadvantages of globalisation are discussed. The author also indicates differences between regions that benefit from globalisation. The article tries to answer questions whether globalisation is a desirable process and what it should (...) be like to bring more benefits than losses. (shrink)

Yuri Gagarin has started the first time in human history the manned mission in space when his Vostok aircraft successfully achieved Earth orbit in 1961. Since his times, human space programs did not develop too much, and the biggest achievement still remain landing on the Moon. Despite this stagnation, there are serious plans to launch manned mission to Mars including human space settlement. In out paper, we are going to identify and discuss a couple of challenges that – in our (...) opinion – will be a domain of every human deep-space program. (shrink)

Having been involved in a slew of recent scandals, many of the world’s largest technology companies embarked on devising numerous codes of ethics, intended to promote improved standards in the conduct of their business. These efforts have attracted largely critical interdisciplinary academic attention. The critics have identified the voluntary character of the industry ethics codes as among the main obstacles to their efficacy. This is because individual industry leaders and employees, flawed human beings that they are, cannot be relied on (...) voluntarily to conform with what justice demands, especially when faced with powerful incentives to pursue their own self-interest instead. Consequently, the critics have recommended a suite of laws and regulations to force the tech companies to better comply with the requirements of justice. At the same time, they have paid little attention to the possibility that individuals acting within the political context, e.g. as lawmakers and regulators, are also imperfect and need not be wholly compliant with what justice demands. This paper argues that such an omission is far from trivial. It creates a heavy argumentative burden on the part of the critics that they by and large fail to discharge. As a result, the case for Big Tech regulation that emerges from the recent literature has substantial lacunae and more work needs to be done before we can accept the critics’ calls for greater state involvement in the industry. (shrink)

Is it wrong to distract? Is it wrong to direct others’ attention in ways they otherwise would not choose? If so, what are the grounds of this wrong – and, in expounding them, do we have to at once condemn large chunks of contemporary digital commerce (also known as the attention economy)? In what follows, I attempt to cast light on these questions. Specifically, I argue – following the pioneering work of Jasper Tran and Anuj Puri – that there is (...) a right to attention, and that its existence underlies some of our claims regarding the wrongness of distractions. However, I depart from both these authors in two respects: first, I present a new way of deriving the right to attention, grounding it in the more fundamental right to mental integrity. Second, I remain agnostic on whether the contemporary business practices of capturing attention in exchange for a variety of digital products and services are plagued by routine violations of the right. (shrink)

The article aims to analyse the thought of Edward Abramowski – a Polish philosopher, pioneer of psychology and theorist of the socialist cooperative movement. It attempts to reconstruct the impact that his social thought and his philosophical anthropology have had on the political activity of Polish cooperativism. In keeping with Michael Freeden’s thesis that an ideologist translates philosophical concepts into political practice, the author sees Abramowski as a thoroughly modern thinker who opened an alternative ideological path to the great political (...) narratives of the day. The article points out the originality of the Polish philosopher’s proposition for the socialist movement, the goal being to achieve the political emancipation of the popular classes through economic activity undertaken by grassroots cooperatives operating outside state structures. The philosophical-sociological concept of ‘fraternity’ or ‘pure socialization’ leads Abramowski to formulate a doctrine of ‘stateless socialism’, in which popular political organizations use primordial, human-based cooperation to create new opportunities for community life. The last parts of the article show links between Abramowski's concepts and the modern school of commoning. The aim of this comparison is to show the doctrine of cooperativism can make a contribution to determining the political stakes of contemporary conflicts regarding biopolitical subjectivity. (shrink)

Streszczenie: Idea sacrum w lirycznej twórczości Dariusza Dekańskiego to konglomerat wielu składowych. Zarówno rzeczywistości konsystencjalnej, jak i tej sensytywnej – wyobrażonej, percypowanej na drodze synestezji. W prezentowanym artykule, pełniącym rolę asumptu do dalszych badań nad poetycką aktywnością autora Saudade, zwrócono szczególną uwagę na więź człowieka z Bogiem, kontakt z sacrum, przejawiającymi się w wewnętrznych przeżyciach podmiotu lirycznego, bezustannie szukającego swojego miejsca w świecie. Aby zbliżyć się do zrozumienia działań bohatera tej poezji wykorzystano przede wszystkim instrumentarium oferowane przez metodologie badań sacrum.

Poetycka twórczość Zdzisława Dębickiego to przykład pisarstwa korzystającego z różnych poetyk, co przejawiało się w wielorakim charakteryzowaniu składających się na nią przestrzeni. Autor Nocy bezsennych, uważany za poetę minorum gentium, umiejętnie wykorzystywał literackie dokonania ówczesnych poetów, powołując do istnienia obszary, pełniące jednocześnie funkcję ekspresji własnej podmiotowości artystycznej. Czytanie liryków Dębickiego pozwala na zestawienie intymnych zwierzeń podmiotu lirycznego z ogołoconą z bogactwa opisu pustą przestrzenią. Przestrzeń, jako jedna z kategorii epistemologiczno-ontologicznych, nie jest dla poety jedynie narzędziem służącym tworzeniu atrakcyjnego obrazka, ale (...) przede wszystkim stanowi asumpt do dociekań poznawczych. (shrink)

Philosophy of immunology is a subfield of philosophy of biology dealing with ontological and epistemological issues related to the studies of the immune system. While speculative investigations and abstract analyses have always been part of immune theorizing, until recently philosophers have largely ignored immunology. Yet the implications for understanding the philosophical basis of organismal functions framed by immunity offer new perspectives on fundamental questions of biology and medicine. Developed in the context of history of medicine, theoretical biology, and medical anthropology, (...) philosophy of immunology differs from these related branches of study in its focus on traditional philosophical questions concerning identity, individuality, ecology, cognition, scientific methodology and theory construction. This broad agenda derives from immunology’s multifaceted research program that has developed from its initial clinical challenges of host defense, transplantation, autoimmunity, tumor immunology, and allergy. In addition to these well-established research areas, immunity is now understood to play a central role in other physiological functions, development, ecology, and evolutionary mechanics. Holding together these diverse domains of inquiry lie philosophical commitments oriented by organismal identity. In this regard, pertinent issues are raised concerning cognition (organization of immune perception and information processing), the character of individuality (framed by the ecological context of immune-mediated assimilation and rejection), and the dynamics of complex systems (understood as holistic systems biology). Indeed, immunology, in the context of cognitive science, evolutionary biology, environmental sciences, and development provides multi-focal perspectives for philosophy of science. (shrink)

According to grounding necessitarianism if some facts ground another fact, then the obtaining of the former necessitates the latter. Proponents of grounding contingentism argue against this claim, stating that it is possible for the former facts to obtain without necessitating the latter. In this article I discuss a recent argument from restricted accidental generalisations provided by contingentists that advances such possibility. I argue that grounding necessitarianism can be defended against it. To achieve this aim, I postulate a relationship between grounding (...) and essence by introducing a notion of individual essences understood as a set of essential properties that individuate its bearer. According to a proposed view grounding holds in virtue of identities of its relata, which are in turn determined by their respective individual essences. From there I claim that if grounding holds in virtue of the individual essences of its relata, then it is possible to resist the objection from restricted accidental generalisations and maintain a view that grounds necessitates what is grounded. (shrink)

The extent to which normal (nonmalignant) cells of the body can evolve through mutation and selection during the lifetime of the organism has been a major unresolved issue in evolutionary and developmental studies. On the one hand, stable multicellular individuality seems to depend on genetic homogeneity and suppression of evolutionary conflicts at the cellular level. On the other hand, the example of clonal selection of lymphocytes indicates that certain forms of somatic mutation and selection are concordant with the organism-level fitness. (...) Recent DNA sequencing and tissue physiology studies suggest that in addition to adaptive immune cells also neurons, epithelial cells, epidermal cells, hematopoietic stem cells and functional cells in solid bodily organs are subject to evolutionary forces during the lifetime of an organism. Here we refer to these recent studies and suggest that the expanding list of somatically evolving cells modifies idealized views of biological individuals as radically different from collectives. (shrink)

Somatic diversification of antigen receptor genes depends on the activity of enzymes whose homologs participate in a mutagenic DNA repair in unicellular species. Indeed, by engaging error-prone polymerases, gap filling molecules and altered mismatch repair pathways, lymphocytes utilize conserved components of genomic stress response systems, which can already be found in bacteria and archaea. These ancient systems of mutagenesis and repair act to increase phenotypic diversity of microbial cell populations and operate to enhance their ability to produce fit variants during (...) stress. Coopted by lymphocytes, the ancient mutagenic processing systems retained their diversification functions instilling the adaptive immune cells with enhanced evolvability and defensive capacity to resist infection and damage. As reviewed here, the ubiquity and conserved character of specialized variation-generating mechanisms from bacteria to lymphocytes highlight the importance of these mechanisms for evolution of life in general. (shrink)

Abstractabstract:The aim of this article is to analyze the close relation between social theory (“sociological phenomenalism”) and the political ideology of the Polish thinker Edward Abramowski. Abramowski’s “applied sociology” involved: (1) the sociology of “fraternity,” examining basic forms of socialization; (2) combining social revolution with ethical self-improvement; and (3) the dissemination of “social laboratories” through the development of a network of cooperatives. As “experiments of the will,” the cooperatives allowed Abramowski to combine science, imagination, and ethics in a coherent project (...) of political utopia-building, extending the possible forms of community. Finally, the article shows that in Abramowski’s case, the meaning of utopia as an element embedded in a wide range of political practices derives from his vision of social science. Due to the influence that Abramowski’s thought had on political reality in Poland, the concept of “experimental” utopia entered the vocabulary of modern social sciences in Poland for good. (shrink)

The terms “eustress” and “distress” are widely used throughout the scientific literature. As of February 2020, 203 items in the Web of Science show up in a search for “eustress,” however, there are almost 16 400 items found in a search for the term “distress.” Based on the reasoning in this article, however, it is believed there is no such thing as eustress or distress. The adaptation reaction of an organism under stress is not intrinsically good or bad, and its (...) effect on health or performance depends on a plethora of other interactions of the body with the environment as well as on the history of such interactions. The vagueness of the terms “eustress/distress” has historically led to vast differences in the perception and application of the terms across disciplines. While psychology or sociology perceive eustress as something inextricably linked to positive perception and enhanced cognition, biomedicine perceives eustress as generally associated with better survival, health, or increased longevity, no matter how the event is perceived. In this paper, the authors review the current understanding of the term “eustress” in different fields, discuss possible implications of its misleading use, and suggest that the term may be replaced by “stress” only. (shrink)

It has long been taken for granted that the immune system’s capacity to protect an individual from infection and disease depends on the power of the system to distinguish between self and nonself. However, accumulating data have undermined this fundamental concept. Evidence against the self/nonself discrimination model left researchers in need of a new overarching framework able to capture the immune system’s reactivity. Here, I highlight that along with the self/nonself model, another powerful representation of the immune system’s reactivity has (...) been developed in the twentieth century immunology. According to this alternative view, the immune system is not a killer of nonself strangers but a peace-maker helping to establish harmony with the environment. The balance view of the system has never become part of the dominant paradigm. However, it is gaining more and more currency as new research develops. Advances in mucosal immunology confirm that instead of distinguishing between self and foreign the immune system reacts to microbial, chemical and self-induced alterations to produce responses that counterbalance effects of these changes. (shrink)

The Metaphysics of Cooperation presents the intellectual achievements of the Polish associative socialist and pioneer of social sciences, Edward Abramowski. The volume is divided into five sections, each of them contains an analysis of Polish philosopher's work according to the issues he dealt with: sociology, ethics, politics, cooperativism, and psychology. Each part also contains a selection of his writings. Its intention is to show Abramowski's works in the context of global intellectual history and to include them in the current political (...) debates. Abramowski makes fraternity or cooperation the main concepts of his social metaphysics. The Polish version of cooperativism can be inspiring both for contemporary researchers and political activists in the post-economic-crisis Europe. It also opens up a space for creating more democratic political and economic institutions. (shrink)

This paper offers a critical review of the notion of a “singular cognitive role”, which is central to some recent theories of singular thought. According to those theories, whether a thought is singular depends on the role it plays in the subject’s cognitive activity. We compare the two most developed accounts of this type: Crane’s :21–43 2011, The Objects of Thought2013) and Jeshion’s. Both theories aim to capture the notion of a singular cognitive role in terms of mental files. We (...) argue that Jeshion’s theory is much more promising as it provides a more detailed and non-circular characterization of the mental files responsible for singular thinking. We examine the prospects for enhancing that account in light of three major concerns about it present in the literature. First, we discuss whether the weakest aspect of the whole proposal, i.e. the condition for the initiation of mental files, can be replaced without debilitating the rest of the theory. Second, we examine Goodman’s : 437–461 2014, The Philosophical Quarterly2015) argument against mental file theories of singular thought and show that it does not affect Jeshion’s account. Third, we argue against Sawyer :264–283 2012) that Jeshion’s notion of a singular cognitive role is in strong opposition to acquaintance-based theories of singular thought and cannot be incorporated into any of them. Thus, the paper concludes that Jeshion’s proposal, despite its shortcomings, is currently the most promising account of a singular cognitive role. (shrink)

The immune system, to protect the body, must discriminate between the pathogenic and non-pathogenic microbes and respond to them in different ways. How the mucosal immune system manages to make this distinction is poorly understood. We suggest here that the distinction between pathogenic and non-pathogenic microbes is made by an integrated system rather than by single types of cells or single types of receptors; a systems biology approach is needed to understand immune recognition.

It might become possible to build artificial minds with the capacity for experience. This raises a plethora of ethical issues, explored, among others, in the context of whole brain emulations (WBE). In this paper, I will take up the problem of vulnerability – given, for various reasons, less attention in the literature – that the conscious emulations will likely exhibit. Specifically, I will examine the role that vulnerability plays in generating ethical issues that may arise when dealing with WBEs. I (...) will argue that concerns about vulnerability are more matters of institutional design than individual ethics, both when it comes to creating humanlike brain emulations, and when animal-like emulations are concerned. Consequently, the article contains reflection on some institutional measures that can be taken to protect the sims' interests. It concludes that an institutional framework more likely to succeed in this task is competitive and poly-centric, rather than monopolistic and centralized. (shrink)

In “Accepting Moral Responsibility for the Actions of Autonomous Weapons Systems—a Moral Gambit” (2022), Mariarosaria Taddeo and Alexander Blanchard answer one of the most vexing issues in current ethics of technology: how to close the so-called “responsibility gap”? Their solution is to require that autonomous weapons systems (AWSs) may only be used if there is some human being who accepts the ex ante responsibility for those actions of the AWS that could not have been predicted or intended (in such cases, (...) the human being takes what the authors call the “moral gambit”). The authors then propose several institutional safeguards to implement in order to ensure that the moral gambit is taken in a fair and just way. This paper explores this suggestion in the context of the institutional settings within which AWSs are most likely to be deployed. It raises some concerns as to the feasibility of Taddeo and Blanchard’s proposal, in light of the recent empirical work on the incentive structures likely to exist within militaries. It then presents a potential problem that may arise in case the accountability mechanisms are successfully implemented. (shrink)

Journal of Applied Philosophy, EarlyView.

Most contemporary models of disease development consider the interaction between genotype and environment as static. The authors argue that because time is a key factor in genotype–environment interaction, this approach oversimplifies the pathology analysis and may lead to wrong conclusions. In reviewing the field, the authors suggest that the history of genotype–environment interactions plays an important role in the development of diseases and that this history may be analyzed using the phenotype as a proxy. Furthermore, a theoretical and experimental framework (...) is proposed based on the assumption that phenotypes do not change from one to another randomly but are interconnected and follow certain phenotype trajectories. It then follows that analysis of such phenotype trajectories might be useful to predict the future phenotypes including the onset of disease. In addition, an analysis of phenotype trajectories can be subsequently used to choose better control subjects in comparative studies reducing noise and bias in studies investigating disease mechanisms. (shrink)