The prospect of using cell-based interventions to treat neurological conditions raises several important ethical and policy questions. In this target article, we focus on issues related to the unique constellation of traits that characterize CBIs targeted at the central nervous system. In particular, there is at least a theoretical prospect that these cells will alter the recipients' cognition, mood, and behavior—brain functions that are central to our concept of the self. The potential for such changes, although perhaps remote, is cause (...) for concern and careful ethical analysis. Both to enable better informed consent in the future and as an end in itself, we argue that early human trials of CBIs for neurological conditions must monitor subjects for changes in cognition, mood, and behavior; further, we recommend concrete steps for that monitoring. Such steps will help better characterize the potential risks and benefits of CBIs as they are tested and potentially used for treatment. (shrink)

An edition of the letters of Erasmus, regarded as one of the greatest humanist writers. All 12 volumes of this work have been reissued, complete with their scholarly apparatus of commentary and notes, as well as plates.

Owen Flanagan is a highly prolific writer and speaker whose work brings together results of research in several empirical disciplines overlapping with philosophy, particularly neuroscience and other areas of psychology. This book of thirteen essays, most of them revisions of work published elsewhere, exhibits both his intellectual and his stylistic range. Many of the essays are light and chatty, others analytical and slower-going.

Монография предназначена для студентов, аспирантов, преподавателей юридических и философских факультетов, а также для всех тех, кто интересуется философско-правовой проблематикой.

Chapter Promising in Law and Morals Promissory and contractual obligations raise many issues of common interest to philosophers and lawyers. ...

Medieval Thomists such as the Dominican master John of Paris, on the other hand, attempted to defend Aquinas against such charges. Adopting Thomas’s notion of the passivity of the will, John nonetheless denied that such a position necessarily interferes with moral responsibility. He justified this stance on the grounds that an agent’s freedom is only violated when it is necessitated contrary to its own nature. Because the will is naturally suited to follow practical deliberation, its necessitation by the intellect leaves (...) its freedom intact. (shrink)