Of knowledge and probability: a quick tour of part 3, book 1. Of knowledge ; Of probability; and of the idea of cause and effect ; Why a cause is always necessary? ; Of the component parts of our reasonings concerning causes and effects ; Of the impressions of the senses and memory ; Of the inference from the impression to the idea ; Of the nature of the idea, or belief ; Of the causes of belief ; Of the (...) effects of other relations, and other habits ; Of the influence of belief ; Of the probability of chances ; Of the probability of causes ; Of unphilosophical probability ; Of the idea of necessary connexion ; Rules by which to judge of causes and effects ; Of the reason of animals -- Hume on unphilosophical probabilities -- Hume's skepticism with regard to reason -- Of skepticism with regard to the senses -- Of the ancient and modern philosophy -- The soul and the self -- The conclusion of book 1 -- Two openings and two closings. (shrink)

Professor Fogelin has provided an authoritative critical evaluation of both the Tractatus Logico-Philosophicus and Philosophical Investigations, making these key texts accessible to the general reader.

There is an ethics of blaming the person who deserves blame. The Christian scriptures imply the following no-vengeance condition: a person should not vengefully overtly blame a wrongdoer even if she gives the wrongdoer the exact negative treatment that he deserves. I explicate and defend this novel condition and argue that it demands a revolution in our blaming practices. First, I explain the no-vengeance condition. Second, I argue that the no-vengeance condition is often violated. The most common species of blame (...) involves anger; anger conceptually includes a desire for vengeance; and there are many pleasures in payback. Third, I clarify that it is possible to blame non-vengefully in anger and highlight three good uses for anger in non-vengeful blame. Fourth, I offer two reasons that justify the divine command prohibiting vengeance, and I note that the Christian God is merely sufficient to make non-vengeance morally obligatory. Fifth, I defend the no-vengeance condition against four biblical objections. (shrink)

Some state‐based newborn screening programs in the United States already use sequencing technology, as a secondary screening test for individual conditions rather than as a broad screening tool. Newborn screening programs sequence an individual gene, such as the cystic fibrosis transmembrane conductance regulator, which causes cystic fibrosis, after an initial biochemical test suggests that a baby might have a condition related to that gene. The experiences of state public health departments with individual‐gene sequencing illustrate both the usefulness of the technology (...) and its complexities. Here I discuss how newborn screening programs investigate cystic fibrosis and, as another example, adrenoleukodystrophy through individual gene sequencing. (shrink)

As the above quote clearly highlights, it is the responsibility of researchers and research supervisors to be certain that their research staff and students assistants are very familiar with all of the ethical principles and current standards relevant to the research they are conducting. Indeed, they must take an active role in being certain that their research staff and students complete appropriate training in these ethical principles and standards, and how they apply them to the research context in which they (...) are working. This is especially important in areas in which there may be physical harm such as chronic pain research. During the past decade, there has been a great increase in research of chronic pain, with breakthroughs in better understanding its etiology, assessment, and treatment (1,2). Obviously, much of this research was conducted using humans and animals as subjects. As a consequence, there were a number of ethical issues that investigators have to be cognizant of when conducting their studies. In this chapter, we will discuss such ethical issues in three major areas: (i) laboratory research with human subjects; (ii) laboratory research with animals; and (iii) translating these laboratory research ndings to ‘‘real world’’ applications in the clinical treatment arena. (shrink)

Arguably the most famous heterotopia that appears in Foucault’s work is the Chinese encyclopedia, which originates in the fiction of Jorge Luis Borges. Drawing on this citation of Borges, this article examines Foucault’s notion of the heterotopia as it relates to order and knowledge production. Frequently, heterotopias are understood as sites of resistance. This article argues that shifting the focus from resistance to order and knowledge production reveals how heterotopias make the spatiality of order legible. By juxtaposing and combining many (...) spaces in one site, heterotopias problematize received knowledge by destabilizing the ground on which knowledge is built. Yet heterotopias always remain connected to the dominant order; thus as heterotopias clash with dominant orders, they simultaneously produce new ways of knowing. This article first explores the tensions between Foucault’s two definitions of heterotopias before connecting these definitions to Foucault’s distinctly spatial understanding of knowledge as emerging from a clash of forces. Finally, the paper ends by returning to the relationship between Foucault, Borges, and heterotopias. (shrink)

This essay presents an exposition and limited defense of Richard Price's claim that the “fidelity to promises is properly a branch or instance of veracity,” i.e., the obligation to keep a promise is, for Price, an instance of our obligation to tell the truth. His general idea is this: When one makes an assertion, one is under an obligation to have one's words fit the facts. When one makes an assertion about one's own future actions, one falls under an obligation (...) to make what one said true by acting in the stated way. Though not without difficulties, Price's account of promising is presented as a viable alternative to accounts given by H. A. Prichard and J. L. Austin. (shrink)

Thomas S. Kuhn’s The Structure of Scientific Revolutions was a watershed event when it was published in 1962, upending the previous understanding of science as a slow, logical accumulation of facts and introducing, with the concept of the “paradigm shift,” social and psychological considerations into the heart of the scientific process. More than fifty years after its publication, Kuhn’s work continues to influence thinkers in a wide range of fields, including scientists, historians, and sociologists. It is clear that The Structure (...) of Scientific Revolutions itself marks no less of a paradigm shift than those it describes. In Kuhn’s “Structure of Scientific Revolutions” at Fifty, leading social scientists and philosophers explore the origins of Kuhn’s masterwork and its legacy fifty years on. These essays exhume important historical context for Kuhn’s work, critically analyzing its foundations in twentieth-century science, politics, and Kuhn’s own intellectual biography: his experiences as a physics graduate student, his close relationship with psychologists before and after the publication of Structure, and the Cold War framework of terms such as “world view” and “paradigm.”. (shrink)

This book is primarily a textual analysis that demonstrates the close relationship of David Hume's The Dialogues Concerning Natural Religion with David Hume's central philosophical writings and its centrality to his relationship with scepticism.

Contrary to explicit statements in the text of the Tractatus Logico‐Philosophicus, this essay argues that the notion of a negative elementary proposition makes sense within the Tractarian system. The suggestion depends upon separating two strains in Wittgenstein's account of propositional meaning: the picture theory of meaning, and the truth‐functional account of meaning. A proposition could be considered elementary if it contained only one elementary proposition or one elementary picture. In this approach, if p is an elementary proposition, then so is (...) not‐p. Though this change would involve substantial revisions of the Tractatus, it squares with Wittgenstein's fundamental view that logical constants are not representatives. (shrink)

This essay attempts to elucidate and restate in modern terms richard price's reduction of our obligation to keep promises to our obligation to veracity. It next defends this reduction against standard criticisms. This defence is, However, Limited, Since the voluntarists (descartes) and the utility theorists (hume), Whom price is most anxious to refute, Could accept this reduction and reassert their theories with respect to our obligation to veracity itself.

George Will, the well-known pundit, once observed: “A society's recreation is charged with moral significance. Sport—and a society that takes it seriously—would be debased if it did not strictly forbid things that blur the distinction between the triumph of character and the triumph of chemistry.” In opposition, Dan Duchaine, the highly publicized “steroid guru” and counter-culture columnist, declared: “There comes a time for many in competitive athletics where winning is more important than those initial goals of health, recreation, and relaxation.” (...) The parallels of these two philosophies to life in general are patent simply by substituting “sports” and “winning” for “career” and “success,” respectively.This paper will review the basis for banning anabolic steroids in athletics, and consider especially the recent medical findings that support this prohibition. This survey leads into a discussion of the available deterrents, and the secondary, but essential, role of random drug testing as a final safeguard. (shrink)