Cet article expose les premiers contacts d’Alexandre Nequam (1157-1217) avec la traduction latine du Liber de causis dans sa proposition 2, et le recours à son ami le théologien Alain de Lille ( c. 1120-1202) qu’il jugea nécessaire. Celui-ci répondit par ses quatre premières Regulae theologicae.

This paper shows that Aristotle's De Interpretatione does not separate syntax from semantics. Linguistic sentences are not syntactic entities, and non-linguistic meanings are not semantic propositions expressed by linguistic sentences. In fact, Aristotle resorts to a mental conception of meaning, distinguishing linguistic meanings in a given language from non-linguistic mental contents in relation to actual things: while the former are not the same for all, the latter are shared by everyone. Aristotle is not a modern logician, like Boole, Frege, or (...) Russell, in so far as a mental conception of meaning does not reveal an abstract semantics for a syntactic language. (shrink)

Aristotle’s Prior Analytics identifies deductions simpliciter with inferential necessity, so that a deduced conclusion is necessarily inferred from some premises. Modern logical reconstructions claim that inferential necessity in Aristotle corresponds to logical validity. However, this logical reconstruction fails on two accounts. First, logical validity does not highlight Aristotle’s distinction between inferential necessity and predicative necessity, meaning that the inferential necessity of a deduction is not of the same kind as the predicative necessity of a non‑deductive argument. Second, logical validity does (...) not explain the relevance of Aristotle’s distinction between complete and incomplete deductions. Logicians speak of complete deduction by adding the term “obvious” or “transparent” to logical validity, and then criticize Aristotle’s view for being unclear. However, Aristotle’s position is not confronted with this difficulty. There is nothing to add to inferential necessity, which already means complete deducibility, as opposed to incomplete deducibility, deemed to be potentially complete. Accordingly, the Prior Analytics reduces the incomplete deductions to the complete deductions in order to prove the potential, inferential necessity of the incomplete deductions. Logical validity would have been faithful to Aristotle’s text, if it had been possible to coin a notion of potential validity, distinct from both validity and invalidity. (shrink)

Many logicians have tried to formalize a modal logic from the Prior Analytics, but the general view is that Aristotle has failed to offer a consistent modal logic there. This paper explains that Aristotle is not interested in modal logic as such. Modalities for him pertain to the relations of predication, without challenging the assertoric system of deductions simpliciter. Thus, demonstrations or dialectical deductions have modal predicates and yet are still deductions simpliciter. It is a matter of distinguishing inferential necessity (...) that applies to every deduction from the modal predicates in the two premises and conclusion. The modality of demonstrations can be either necessary or possible. The necessity is predicative, i.e., independent of inferential necessity. While the possible demonstration challenges the predicative necessity of the necessary demonstration, it preserves the inferential necessity of the deduction simpliciter. (shrink)

Hox proteins are part of the conserved superfamily of homeodomain‐containing transcription factors and play fundamental roles in shaping animal body plans in development and evolution. However, molecular mechanisms underlying their diverse and specific biological functions remain largely enigmatic. Here, we have analyzed Hox sequences from the main evolutionary branches of the Bilateria group. We have found that four classes of Hox protein signatures exist, which together provide sufficient support to explain how different Hox proteins differ in their control and function. (...) The homeodomain and its surrounding sequences accumulate nearly all signatures, constituting an extended module where most of the information distinguishing Hox proteins is concentrated. Only a small fraction of these signatures has been investigated at the functional level, but these show that approaches relying on Hox protein alterations still have a large potential for deciphering molecular mechanisms of Hox differential control. (shrink)

Editor's suggested further reading in BioEssays ftz Evolution: Findings, hypotheses and speculations (response to DOI 10.1002/bies.201100019) AbstractOn the border of the homeotic function: Re‐evaluating the controversial role of cofactor‐recruiting motifs AbstractControl of DNA replication: A new facet of Hox proteins? AbstractClassification of sequence signatures: a guide to Hox protein function Abstract.

In lieu of an abstract, here is a brief excerpt of the content:BOOK REVIEWS 551 Human Embryo Research: Yes or No?. By CIBA FOUNDATION. London: Tavistock: 1987. Pp. xv + 232. $39.95 (cloth). In 1984 a governmental commission formed under the directorship of Dame Mary Warnock studied proposed legislation for experimentation on human embryos for research purposes. It concluded that such experimentation should not be permitted ·after the fourteenth day of gestation. This book records a symposium conducted under the sponsorship (...) of the CIBA foundation, an international scientific and educational organization which promotes research into biomedical and chemical research. The purpose of the symposium was to determine whether the guidelines set forth by the Warnock commission were legitimate and whether new criteria for allowing embryo r.esearch should be established. The book consists of eleven papers presented at a symposium on the ethics of embryo research along with panel discussions about the papers. Technically, embryo research only concerns experimentation with human products of conception after the fourteenth gestational day. The first seven papers describe contemporary embryo research dealing with the diagnosis and mechanisms of infertility, its ti;eatment by in vitro fertilization, the diagnosis of genetic disease, the causes and avoidance of congenital malformations, and the improvement of contraception. The final four papers deal with the issues of the status of the human embryo in d:ffierent world religions, the moral arguments against human embryo research, and public attitudes on human embryo research. The scientific papers are quite detailed, and they provided a good deal of information about the contemporary state of embryo research. But the papers on the ethics of human embryo research are rather partisan, and they do not adequately approach the difficult human and ethical issues involved in embryo research. One gains the impression from this book that the conference was heavily weighted in favor of those who sought virtually unqualified and unrestricted moral and legal permission for human.embryo research. The scientific papers seemed to go out of their way to argue that there was an unbreakable continuum in the process of transmitting life such that it could not be determined when human life began. For example, Professor Teresa Iglesias's suggestion that a new and distinct human life began when the process of fertilization began, and when the newly formed genetic material came to govern the development of the organism, rceeived little acknowledgment. No papers were presented rejecting nontherapeutic research on human embryos, and.the papers presented by J. W. Bowker and by Bernard Williams argued in behalf of the moral licitness of unspecified forms of embryo research. Bowker claimed that there was no consensus to be found 55~ BOOK REVIEWS among the various world religions on the moral status of the human embryo. He surveyed various religions such as Buddhism and concluded that the arguments in favor of the humanity or personhood of the embryo were not strong or persuasive. His point should not be accepted without caution, however, for he did not consider the claims made by western traditions such as Catholicism in behalf of the personhood of the embryo. 'F:or the claims of an oriental religion such as Buddhism are not as persuasive with Western, rationalist, liberal minds as they are with orientals. Bowker argues that religious claims about the personhood of the unborn ';are weak since we do not claim that larvae are full grown fish or that acorns are oak trees. This is true, but on the other hand, we do not say that horse embryos are vegteables or pigs. Implied in Bowker's claim that the embryo is not a human being or a human person is the assumption that at some point in the gestation process the embryo undergoes a "species-transfer" or "class-transfer" from the biological category of non-human or non-personal to human and personal. This is difficult to accept as there is no precedent in other mammals for such a species or class transfer. Equine, bovine, and canine embryos are not considered to be anything than other than of the species of horse, pig, or dog, and there is no reason to believe that they engage in some sort of species transfer. And he does not explain why the human case alone exhibits this... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:156 BOOK REVIEWS of theological method in Aquinas (p. 193; see also pp. 57 and 173). But this is not sufficient. Farthing should have acknowledged that Biel's recurrent critique of the supposed ' positive ' use of reason in Aquinas is beside the point and that, by thinking that Thomas is trying to ' demonstrate ' the faith, Biel has carelessly dismissed much that is interesting and valuable in (...) Aquinas. By bringing Biel's error to the fore, Farthing would have made clear to the reader that in this crucial respect, the dialogue between these two thinkers has completely broken down. University of Notre Dame Notre Dame, Indiana JOSEPH WAWRYKOW The Reshaping of Catholicism: Current Challenges in the Theology of Church. By AVERY DULLES. San Francisco: Harper & Row, 1988. Pp. 276. $19.95 (doth). Each of Dulles's twelve articles commends itself no less as a chapter in this collection than when it first appeared separately between 1984 and the end of 1987. In ensemble, " they give," Dulles remarks in his Preface, " a fair sampling of the issues the Catholic Church has had to face in the two decades since the Council." Whatever the leading Catholic ecclesiologist in America has to say about specific problems in Church renewal deserves careful attention. A positive general evaluation of the book is all hut a foregone conclusion. Still, a review can perform that opening survey of contents that will lend precision to a reader's anticipation of what the author has singled out as the current challenges. Four chapters take up the task of interpreting the texts of Vatican II, not as a species of source-criticism but in light of post-conciliar difficulties. Chapters 2 ("The Basic Teaching of Vatican II "), 5 ("Vatican II and the Recovery of Tradition"), and 8 ("Vatican II and the Purpose of the Church") emerge from a situation of divided opinion. They also apply the Council's teaching as a solution. Chapter 7 ("The Church and Communications") likewise engages conciliar texts, along a more speculative line. Chapter 1 ("American Impressions of the Council") joins with 2 in opening the book at a somewhat more popular level. The other chapters employ conciliar teaching to formulate theological answers to some important questions. These are questions which trouble not only the hierarchy and the theologians but also ordinary BOOK REVIEWS 157 members of the Church, as they come to terms with the Church's renewed self-understanding. Chapter 3 (" The Emerging World Church and the Pluralism of Cultures") picks up where Karl Rahner's wellknown address at the Weston School of Theology in 1979 left off. Dulles accepts Rahner's argument that Vatican II achieved the first official self-actualization of Catholicism as a world church. Taking the resulting problem of inculturation as the current phase in the relation between Christianity and culture, Dulles specifies the relation between two cultures as "cultural reciprocity." He leaves behind the simple, familiar contrast between classicism and a non-normative concept of culture. His ecumenical research enters into Chapter 4 ("The Meaning of Catholicism: Adventures of an Idea "), which places Vatican II in the context of two centuries of Protestant-Catholic discussion on the essence or basic idea of Catholicism. Intra-Catholic pluralism turning into opposition underlies most of the hook, hut Chapters 5 and 6 ("Authority and Conscience: Two Needed Voices") treat two such polarizations thematically. In 5 Dulles finds Dei Verbum open to an understanding of tradition as the handing on from generation to generation of the " tacit knowledge " whose content is the lived awareness of the God of Jesus Christ. Chapter 6 does not admit a second, alternative magisterium, hut it does situate hier· archical teaching amid the several sources of authority accepted by Catholicism-Scripture, tradition, the whole People of God, and theologians along with the hierarchy. And, in the formation of personal judgments and decisions, conscience has its own authority. A theology of communication follows from each of five models of the Church. Chapter 7 shows how this, in turn, implies a distinct approach to evangelization, use of mass media, and episcopal and papal teaching. Chapters 8 and 9 {"The Church, Society, and Politics") discuss the tensions inherent in the Church's mission... (shrink)

In chapter 3 of Genesis, the serpent speaks to Eve and foretells: if Adam and Eve taste the fruit, their eyes will open and they will be like gods, “knowing good and evil” (iii, 5). As soon as the...