In the past 2 decades latent variable modeling has become a standard tool in the social sciences. In the same time period, traditional linear structural equation models have been extended to include non-linear interaction and quadratic effects (e.g., Klein and Moosbrugger, 2000 ), and multilevel modeling (Rabe-Hesketh et al., 2004 ). We present a general non-linear multilevel structural equation mixture model (GNM-SEMM) that combines recent semiparametric non-linear structural equation models (Kelava and Nagengast, 2012 ; Kelava et al., 2014 (...) ) with multilevel structural equation mixture models (Muthén and Asparouhov, 2009 ) for clustered and non-normally distributed data. The proposed approach allows for semiparametric relationships at the within and at the between levels. We present examples from the educational science to illustrate different submodels from the general framework. (shrink)

Maximum likelihood (ML) estimation of categorical multitrait-multimethod (MTMM) data is challenging because the likelihood involves high-dimensional integrals over the crossed method and trait factors, with no known closed-form solution. The purpose of the study is to introduce three newly developed ML methods that are eligible for estimating MTMM models with categorical responses: Variational maximization-maximization (e.g., Rijmen and Jeon, 2013 ), alternating imputation posterior (e.g., Cho and Rabe-Hesketh, 2011 ), and Monte Carlo local likelihood (e.g., Jeon et al., under (...) revision). Each method is briefly described and its applicability for MTMM models with categorical data are discussed. (shrink)

This article considers Peter Bowler's recent contribution to the genre of counterfactual history as exemplifying a “restrained” counterfactual framework, one that must downplay the role of contingency in the historical process in order to present what Bowler calls a more “natural course” of historical development. This restrained counterfactual methodology is discussed with reference to analogous debates within evolutionary science about the competing roles of contingency and convergence in the history of life, along with recent work done within the humanities about (...) the more subtle nuances of counterfactual reasoning. Although there is little doubt that Bowler's study will help legitimize the genre of counterfactual history, it is argued that the role of contingency—once thought to be integral to the counterfactual—has been necessarily minimized in order to construct a narrative that is a plausible counterfactual history of science. It is in this way that Bowler's world without Darwin sheds light on our historiographical preconceptions about what makes for a plausible historical narrative. (shrink)

_ Source: _Volume 9, Issue 2, pp 196 - 219 In his 1978 On Human Nature, Edward Wilson defined the evolutionary epic as the scientific story of all life, a linear narrative beginning with the big bang and ending with the story of human history. Since that time several popular science writers have attempted to write that story of life producing such titles as The Universe Story and The Epic of Evolution. Historians have also gotten into the act under the (...) guise of “Big History,” which has resulted in a series of monographs and is taught at several universities and high schools throughout the world. While the evolutionary epic is often presented as a novel way of bringing the historical insights of modern science into a narrative form that transcends the humanities–natural science divide, the genre itself originates in the nineteenth century, just as new geological and cosmic timescales were being established and new sciences such as biology and anthropology were being formalized. Several German Naturphilosophen and Victorian naturalists imagined the history of life as one, as a “Cosmos,” and produced evolutionary epics that bare significant similarities with their more modern counterparts. By considering the various recurrences of the evolutionary epic, from its origins in early German Romanticism and Victorian naturalism to the degeneration narratives of the fin de siècle and on to the Wilsonian and Big History versions of the late twentieth century and beyond, this essay seeks to map out a shared intellectual genealogy while examining the genre’s conceptual commonalities. What is perhaps most compelling about the history of the genre is the striking persistence of non-Darwinian forms of evolution that are utilized to situate the emergence of humanity in these epic narratives of life. (shrink)

ABSTRACT One of the most influential imagined histories of science of the nineteenth century was John Tyndall's Belfast Address of 1874. In that address, Tyndall presented a sweeping history of science that focused on the attempt to understand the material nature of life. While the address has garnered attention for its discussion of the conflict at the centre of this history, namely between science and theology, less has been said about how Tyndall's history culminated with a discussion of the evolutionary (...) researches of Charles Darwin. Tyndall presented Darwin as a revolutionary scientific practitioner, whose virtues of patience, self-denial, and observation led him to his epochal theory of evolution and thus justified the extension of science into realms previously under the purview of theology. Tyndall was criticized at the time for his ‘vulgar admiration’ of a man of science who was still very much alive, and who could not possibly live up to such ‘fulsome adulation’. What such critics failed to realize, however, is that Tyndall had historicized the living Darwin within the context of his own philosophy of history that he cultivated years before, a philosophy that integrated the moral lives of heroic individuals within a progressive history of science itself. (shrink)

In this paper, my aim is to offer some comments on the study of Mu‘tazilite kalām, framed around the study of a particular episode in the Mu‘tazilite dispute about man – a question with a deceptively Aristotelian cadence that is not too difficult to dispel. Within this episode, my focus is on one of the major arguments used by the late Baṣrans to hold up their side of the dispute, and on the relationship between the mental and the physical which (...) emerges from it. The most interesting – and most surprising – aspect of this relationship is that the mental and the physical do not seem to be treated as distinct terms, thus creating the space for questions about how the two relate. The first person perspective seems to be identified with the physical body. My interest then is in the response of the reader to this surprising presentation – or rather, in a certain kind of reader response, and thus a certain kind of interpretive mode, whose value and viability it is part of my aim to help clarify. (shrink)

Throughout the twentieth century, the automation of formal logics in computers has created unprecedented potential for practical applications of logic—most prominently the mechanical verification of mathematics and software. But the high cost of these applications makes them infeasible but for a few flagship projects, and even those are negligible compared to the ever-rising needs for verification. One of the biggest challenges in the future of logic will be to enable applications at much larger scales and simultaneously at much lower costs. (...) This will require a far more efficient allocation of resources. Wherever possible, theoretical and practical results must be formulated generically so that they can be instantiated to arbitrary logics; this will allow reusing results in the face of today’s multitude of application-oriented and therefore diverging logical systems. Moreover, the software engineering problems concerning automation support must be decoupled from the theoretical problems of designing logics and calculi; this will allow researchers outside or at the fringe of logic to contribute scalable logic-independent tools. Anticipating these needs, the author has developed the Mmt framework. It offers a modern approach towards defining, analyzing, implementing, and applying logics that focuses on modular design and logic-independent results. This paper summarizes the ideas behind and the results about Mmt. It focuses on showing how Mmt. provides a theoretical and practical framework for the future of logic. (shrink)

In today’s globalized world, nations cannot be totally isolated from or indifferent to their neighbors, especially in regards to medicine and health. While globalization has brought prosperity to millions, disparities among nations and nationals are growing raising once again the question of justice. Similarly, while medicine has developed dramatically over the past few decades, health disparities at the global level are staggering. Seemingly, what our humanity could achieve in matters of scientific development is not justly distributed to benefit everyone. In (...) this paper, it will be argued that a global theoretical agreement on principles of justice may prove unattainable; however, a grass-roots change is warranted to change the current situation. The UNESCO Declaration on Bioethics and Human Rights will be considered as a starting point to achieve this change through extracting the main values embedded in its principles. These values, namely, respecting human dignity and tending to human vulnerability with a hospitable attitude, should then be revived in medical practice. Medical education will be one possible venue to achieve that, especially through role models. Future physicians will then become the fervent advocates for a global and just distribution of health care. (shrink)

Berichte zur Wissenschaftsgeschichte, Volume 45, Issue 1-2, Page 55-86, June 2022.

This book defends an original and pluralist theory of when and why discrimination wrongs people, in particular, through unfair subordination, through the violation of their right to a particular deliberative freedom, or through the denial to them of access to a basic good.

El presente artículo parte del presupuesto de que el trabajo de la memoria tiene un efecto transformador y liberador, si es llevado a cabo de forma dinámica, creativa y participativa. Como se verá, las experiencias y producciones estéticas adquieren aquí una función destacada, especialmente cuando se comparten de manera abierta y solidaria en una comunidad. Se argumentará que el fomento del trabajo productivo de la memoria con medios estéticos es una labor que no puede ni debe terminar nunca, puesto que (...) tiene una importancia vital para los procesos emancipadores del ser humano. Cuando se activa el potencial productivo y transformador de la memoria, se trascienden historias cerradas, unívocas y homogéneas, como las que propaga una memoria meramente reproductiva, puesta al servicio de una ideología imperante. Esta tesis central será analizada en sus implicaciones filosóficas y discutida contraponiendo la «memoria comunitaria», esencialmente productiva y transformadora, a la «memoria oficial» que procede de manera reproductiva y manipulativa. Ejemplos de iniciativas comunitarias del contexto colombiano ilustrarán finalmente de qué manera medios estéticos pueden despertar y fomentar una memoria crítica y transformadora, capaz de convertir historias cerradas, ignoradas o reprimidas en posibilidades que se abren a la vida. PALABRAS CLAVE: rememoración ; transformación. (shrink)

After completing or dropping out of school, many young people leave their family households and in some cases they move from rural or semi-rural areas to urban centres. Faith-based organisations in major cities in South Africa sometimes act as a safety net for marginalised youth, especially as government departments are overburdened and not addressing all the needs of youth at the margins. This qualitative research is based on an analysis of individual and focus group interviews undertaken with young people living (...) in the central areas of Pretoria. It is shown how families and FBOs engage as separate, although at times not unrelated, entities in the lives of youth at the margins. In certain cases, the FBO became an institution of last resort and only in rare cases is a certain synergy achieved between FBOs and families. (shrink)

Resumen: Espacio y tiempo son conceptos inseparables. La relación que los une es tan estrecha que el espacio puede considerarse la otra cara del tiempo, y viceversa. La unidad y a la vez alteridad espacio-temporal representa un problema fundamental tanto para la ciencia, especialmente la física, como para la filosofía y el arte. Aunque puede haber puntos de encuentro entre las concepciones de las diferentes áreas, se observan diferencias fundamentales en la manera de entender ambos conceptos y la relación entre (...) ellos. El espacio y tiempo de la física clásica y el espacio lógico de Wittgenstein, ligado al presupuesto de la simultaneidad, son presuposiciones teóricas necesarias para establecer leyes físicas o bien para lograr representaciones exactas. Frente a la noción científica y transcendental está la concepción ontológica de Heidegger y la artística de Chillida. Renunciando al ideal de la exactitud, de lo medible y comprobable, el filósofo y el escultor entienden la mutua pertenencia de espacio y tiempo como algo que tiene una importancia fundamental para la vida humana y que representa un reto que hay que buscar.: Space and time are inseparable concepts. The relationship that joins them is so close that one can understand space as the opposite side of time, and vice versa. Unity and otherness of space and time constitute a fundamental problem for science, especially physics, as well as for philosophy and art. Although there may be connecting lines between the conceptions those different fields hold on space and time, one observes fundamental differences in the way they understand these two concepts and the relation between them. The conception of space and time in classical physics, as well as in Wittgenstein’s notion of logical space connected with the principle of simultaneity, represent necessary theoretical premises in order to establish physical laws and precise representations. Opposite to the scientific and transcendental concepts, we find Heidegger’s ontological and Chillida’s artistic conceptions. Giving up the ideal of precision, of measurement and verification, the philosopher and the sculptor understand the mutual belonging of space and time as something that has a fundamental importance in human life, and that constitutes a challenge that one can only search for. (shrink)

Die Wissensvermittlung in Gesundheitsethik ermöglicht es Auszubildenden der Pflege, sich in ihrer zukünftigen Tätigkeit bei Entscheidungsprozessen des Behandlungsteams hinsichtlich pflegeethischer Fragestellungen einzubringen. Vor diesem Hintergrund wurde anhand der vorliegenden Studie die Entwicklung moralischer Positionen sowie pflegeethischer Kenntnisse von Pflegeauszubildenden sichtbar gemacht. An zwei Krankenpflegeschulen (Berlin und Fürth) wurden im Rahmen einer Panelstudie von August 2010 bis März 2011 Daten einer ersten Querschnittserhebung von Auszubildenden in der Pflege erhoben. Für die Studie wurde ein strukturierter Fragebogen verwendet. Die Studienteilnahme erfolgte freiwillig. Alle (...) Auszubildenden hatten vor der Befragung in unterschiedlichem Umfang Unterricht in Gesundheitsethik erhalten. An beiden Standorten zeigten die Teilnehmenden einen Zuwachs an pflegeethischen Kenntnissen. Auszubildende, die bislang keine praktische Erfahrung mit Sterbehilfe gemacht hatten, zeigten Schwierigkeiten in der theoretischen Handhabung dieser Maßnahmen. Für alle Auszubildenden zeigte sich ein allgemeiner Trend zu einer Befürwortung des partizipativen Interaktionsmodells und damit zu einer Förderung der Patientenselbstbestimmung. Zugleich schätzten die Studienteilnehmenden die Fähigkeiten von Patienten, medizinisch richtige Therapieentscheidungen zu treffen, als gering ein. Die Ausbildung in Gesundheitsethik besitzt ein großes Potential, Kenntnisse zu vermitteln und dadurch die ethische Kompetenzentwicklung zu befördern. Unsere Ergebnisse werfen die Frage auf, inwieweit es einer Integration praktischer Erfahrungen mit Fragestellungen der Gesundheitsethik bedarf, um eine praxisrelevante und wissenschaftlich fundierte Wissensvermittlung zu gewährleisten. (shrink)

Background Encounters of moral distress have long-term consequences on healthcare workers’ physical and mental health, leading to job dissatisfaction, reduced patient care, and high levels of burnout, exhaustion, and intentions to quit. Yet, research on approaches to ameliorate moral distress across the health workforce is limited. Research Objective The aim of our study was to qualitatively explore multi-professional perspectives of healthcare social workers, chaplains, and patient liaisons on ways to reduce moral distress and heighten well-being at a southern U.S. academic (...) medical center. Participants & Research Context Purposive sampling and chain-referral methods assisted with recruitment through hospital listservs, staff meetings, and newsletters. Interested participants contacted the principal investigator and all interviews were conducted in-person. Consent was attained prior to interviews. All interviews were recorded and transcribed verbatim. Research Design Directed content analysis was used to deductively organize codes and to develop themes in conjunction with the National Academy of Medicine’s National Plan for Health Workforce Well-Being. Rigor was attained through peer-debriefing, data triangulation methods, and frequent research team meetings. Ethical Considerations Ethics approval was obtained from the university and medical center institutional review boards. Findings Themes demonstrate that rather than offering interventions in the aftermath of moral distress, multilevel daily practices ought to be considered that pre-emptively identify and reduce morally distressing encounters through (1) the care team, (2) management and leadership, and (3) the health care industry. Strategies include interdisciplinary decision-making, trusting managerial relationships, and organizational policies and practices that explicitly invest in mental health promotion and diverse leadership opportunities. Conclusion Moral distress interventions ought to target short-term stress reactions while also addressing the long-term impacts of moral residue. Health systems must financially commit to an ethical workplace culture that explicitly values mental health and well-being. (shrink)

Despite inroads made by critical realism against the ‘scientific method’ in social science, the latter remains strong in subject-areas like human resource management. One argument for the alleged superiority of the scientific method (i.e. its scientificity) lies in the taken-for-granted belief that it alone can formulate empirically testable predictions. Many of those who employ the scientific method are, however, confused about the way they understand and practice prediction. This paper takes as a case study empirical research on the alleged empirical (...) association between human resource management practices and organisational performance. By unpacking the confusion surrounding the two basic notions of prediction used, it reveals what is wrong with them, why the scientific method cannot actually make accurate predictions and why, therefore, the scientific method fails to meet its own criteria for scientificity. Finally, explanation is considered in order to prevent any confusion between it and prediction and to offer what we call tendential prediction. (shrink)

Despite inroads made by critical realism against the ‘scientific method’ in social science, the latter remains strong in subject-areas like human resource management. One argument for the alleged superiority of the scientific method (i.e. its scientificity) lies in the taken-for-granted belief that it alone can formulate empirically testable predictions. Many of those who employ the scientific method are, however, confused about the way they understand and practice prediction. This paper takes as a case study empirical research on the alleged empirical (...) association between human resource management practices and organisational performance. By unpacking the confusion surrounding the two basic notions of prediction used, it reveals what is wrong with them, why the scientific method cannot actually make accurate predictions and why, therefore, the scientific method fails to meet its own criteria for scientificity. Finally, explanation is considered in order to prevent any confusion between it and prediction and to offer what we call tendential prediction. (shrink)

This essay examines the publishing and reception of J. R. Seeley’s Natural Religion, a book that sought to bring about a reconciliation between science and religion. While Natural Religion has long been overlooked, it is argued that its reception gives us insight into changing views about the relationship between science and religion in the late Victorian period. The essay also explores how the reception of the book was conditioned by its bibliographic lineage as it was signed not by Seeley, but (...) “by the Author of Ecce Homo.”. (shrink)

Zusammenfassung Digitale Programme unterstützen mittlerweile sowohl die Erhebung des Pflegebedarfs und die Pflegeplanung als auch die Dokumentation der geleisteten Pflege. Neben Verbesserungen ergeben sich jedoch auch Spannungen zwischen der Verrichtungsorientierung und Standardisierung der digitalen Systeme und dem Fürsorgeethos der Pflege. Daher sind digitale Systeme sowohl aus pflegefachlicher als auch aus pflegeethischer Sicht zu beleuchten, um Chancen und Risiken aufzuzeigen. Pflegeverständnis und Pflegeziele werden in digitalen Programmen nicht explizit gemacht. Bedingt durch die mangelnde Transparenz können sich professionell Pflegende mit gegebenenfalls anderen (...) Pflegeverständnissen nicht dazu verhalten und von den Gepflegten auch keine angemessene Zustimmung zu Pflegemaßnahmen und -zielen einholen. Die Analyse einiger gängiger Programme zeigt, dass digitale Systeme zur somatischen Verkürzung der Pflege tendieren. So werden derzeit Ziele und Maßnahmen zur Kommunikation, Beziehungsgestaltung und Begleitung in Phasen von Krankheit und Sterben kaum abgebildet. In der Einführung digitaler Systeme liegt im Grunde die Chance eines Neubeginns, da sie durch digitale Normierungen zu stärkerer Patientenorientierung und Partizipation beitragen könnten. Es sollte zugleich jedoch die Partizipation der Betroffenen gewährleistet und die Transparenz und Veränderbarkeit der Systeme gewährleistet sein. (shrink)

For the past 40 years, the 14-day rule has governed and, by defining a clear boundary, enabled embryo research and the clinical benefits derived from this. It has been both a piece of legislation and a rule of good practice globally. However, methods now allow embryos to be cultured for more than 14 days, something difficult to imagine when the rule was established, and knowledge gained in the intervening years provides robust scientific rationale for why it is now essential to (...) conduct research on later stage human embryos. In this paper, I argue that the current limit for embryo research in vitro should be extended to 28 days to permit research that will illuminate our beginnings as well as provide new therapeutic possibilities to reduce miscarriage and developmental abnormalities. It will also permit validation of potentially useful alternatives. Through consideration of current ethical arguments, I also conclude that there are no coherent or persuasive reasons to deny researchers, and through them humanity, the knowledge and the innovation that this will generate. (shrink)

Sequences play a great role in mathematical communication. In mathematical notation, we use sequence ellipsis (. . . ) to denote "obvious" sequences like 1, 2, . . . , 7, and in conceptualizations sequence constructors like (i 2+1) i∈N. Furthermore, sequences have a prominent role as argument sequences of flexary functions. While the former cases can adequately be represented and reasoned about as domain objects in Open- Math and MathML, argument sequences are at the language level, and can only (...) be represented, but not reasoned with, since the necessary (sequence-schematic) axioms cannot be represented in the language. (shrink)

Very often, when a belief or a method of reasoning strikes us as morally wrong, it also seems to wrong someone in particular. For instance, if an acquaintance j.

Aristotle's account of female nature has received mostly negative treatment, emphasising what he says females cannot do. Building on recent research, this book comprehensively revises such readings, setting out the complex and positive role played by the female in Aristotle's thought with a particular focus on the longest surviving treatise on reproduction in the ancient corpus, the Generation of Animals. It provides new interpretations of the nature of Aristotle's sexism, his theory of male and female interaction in generation, and his (...) account of inherited features. It also discusses a range of more general issues which can and should be re-examined in light of Aristotle's account of female animals: his methodology, hylomorphism, teleology and psychology. Aristotle on Female Animals will be valuable to all those interested in Aristotle's philosophy and the history of gender. (shrink)

In cases of self-gaslighting, the subject worries that other people will be skeptical of one of her beliefs—for instance, the belief that she has been sexually harassed. Prompted by this worry, she...