Mitotic spindles constitute the machinery responsible for equidistribution of the genetic material into each daughter cell during cell division. They are transient and hence quite labile structures, changing their morphology even while performing their function. Biochemical, immunological and genetic analyses of mitotic cells have allowed us to identify a variety of molecules that are recruited to form the spindle at the onset of mitosis. Evaluation of the roles of these molecules in both the formation and in the dynamics of spindle (...) microtubules should be important for understanding the molecular basis of mitosis and its regulation. We have recently identified a novel mitosis‐specific microtubule‐associated protein (MAP) using a monoclonal antibody probe raised against the mitotic spindles isolated from cultured mammalian cells. This 95/105 kDa antigen represents a unique component of the spindle distinct from any of the other MAPs reported so far. Antibody microinjection resulted in mitotic inhibition in a stage‐specific and dosedependent manner, indicating that the protein is an essential spindle component. (shrink)

It is generally acknowledged that onomatopoeia poses challenges for translation. However, there is little research into the translation of onomatopoeia in Pragmatics. This study seeks to examine the nature of onomatopoeia and its implications for translation from the perspective of relevance theory, addressing, in particular, the following questions: Can notions from pragmatics help to account for the perceived challenges involved in translating onomatopoeia? Would the showing-meaning nature affect the translation of onomatopoeia? What other factors result in difficulties in translating onomatopoeia (...) and why? To this end, a corpus-based analysis of onomatopoeia was conducted using user-generated data provided by Cookpad Inc. Findings show that the relevance-theoretic notions of the showing-meaning continuum and perceptual resemblance can indeed help account for the perceived challenges in translating onomatopoeia. Findings also show that stylistic aspects, such as types of expressions and text types, also impact on the translation of onomatopoeia. (shrink)

The role of figurative languages such as metaphor and metonymy in creativity has been studied in cognitive linguistics. These methods can also be applied to analyze non-linguistic data such as pictures and gestures. In this paper we analyze fashion design by focusing on visual metaphor and metonymy. The nature of creativity in fashion design is not fully studied from a cognitive perspective compared to other related fields such as art. We especially focus on the aspect of fashion design as a (...) communication tool between the designer and the audience to convey designer’s image of human. Photos from two fashion shows are analyzed. We carried out an experiment to compare how human images in two shows are interpreted by those who are familiar with fashion and those who are not. We got three results: (1) As far as figurative (metaphorical and metonymic) interpretations of human image are concerned, two groups with different familiarity to fashion have significantly different patterns of responses to two shows. (2) For non-figurative interpretations (such as physical or personal attributes), no significant difference in the pattern of response to the show was observed between two groups. The participants as a whole, however, responded to the two shows differently. (3) In addition for non-figurative interpretation, fashion experts found significantly more attributes in human images than the others. The results show that the analysis of figurative interpreations is effective in seeing how the familiarity to fashion affects the mode of seeing fashion shows. (shrink)

In a reenactment, a speaker re-presents or depicts a previously occurring event, often dramatically. In this article we examine the role of gaze in reenactments in conversations from Japanese and American English. Following Goodwin in viewing a reenacted story as ‘a multi-modal, multi-party field of activity’, we show how tellers’ and recipients’ gaze during reenactments is deployed to achieve specific interactional ends. We argue that there are two layers of activities involved in doing reenacting – a) the habitat of the (...) original event; b) the habitat of the reenacting event, including the dynamics of gaining appreciative recipiency – and show how they are interwoven in the joint production of a reenactment. (shrink)

Since the inception of modern approaches to grammar, Japanese ga has been treated as a marker indicating the grammatical relation `subject.' If this is an accurate characterization of ga, then we would expect ga to occur to mark a grammatical category consisting of `A' and `S'. Our examination of the contexts in which ga is actually used in everyday Japanese conversations shows that this expectation is not borne out. Our findings suggest that it is not appropriate to describe ga in (...) terms of a grammatical relation such as `subject', and that ga may be much less a grammatical marker than a discourse-pragmatic one. (shrink)

The Expressiveness of the Body meditates on the contrasts between the human body described in classical Greek medicine and the body as envisaged by physicians in ancient China.

Purpose This study aims to map Swedish students’ attitudes towards Snowden’s revelations and their effects in the political and socio-cultural environment of Sweden. Design/methodology/approach A questionnaire was answered by 190 Swedish university students. The quantitative responses to the survey and qualitative considerations of free text answers were statistically analysed. Findings Swedish students had a high level of knowledge about the Snowden revelations; they actively searched for information, gave a positive judgement of Snowden’s actions and were willing to follow his example (...) in Sweden, although not in the USA. They trusted their country and most of its institutions and authorities except for secret service agencies and the internet and computer software companies. Practical implications This study could be used as a design of education for university students, especially in information technology programmes. Social implications The study can be used for developing and applying policies on privacy, surveillance and whistle-blowing. Originality/value This study is part of a bigger international study to map students’ attitudes towards Snowden’s revelations and their opinions about privacy, surveillance and whistle-blowing opening up for cross-cultural analyses. (shrink)

This article provides an experimental analysis of attitude toward imprecise and variable information. Imprecise information is provided in the form of a set of possible probability values, such that it is virtually impossible for the subjects to guess or estimate, which one in the set is true or more likely to be true. We investigate how geometric features of such information pieces affect choices. We find that the subjects care about more features than the pairs of best-case and worst-case, which (...) is a counter-evidence to the well-known models, maximin and α-maximin. We find that presence of nonextreme points in the set affects choice, which suggests that attitude toward imprecision is ‘nonlinear.’ We also obtain an observation, though not significant, that information pieces have a complementarity that may not be explained by the Bayesian view. (shrink)

We invite systematic consideration of the metaphors of cycles and circulation as a long-term theme in the history of the life and environmental sciences and medicine. Ubiquitous in ancient religious and philosophical traditions, especially in representing the seasons and the motions of celestial bodies, circles once symbolized perfection. Over the centuries cyclic images in western medicine, natural philosophy, natural history and eventually biology gained independence from cosmology and theology and came to depend less on strictly circular forms. As potent ‘canonical (...) icons’, cycles also interacted with representations of linear and irreversible change, including arrows, arcs, scales, series and trees, as in theories of the Earth and of evolution. In modern times life cycles and reproductive cycles have often been held to characterize life, in some cases especially female life, while human efforts selectively to foster and disrupt these cycles have harnessed their productivity in medicine and agriculture. But strong cyclic metaphors have continued to link physiology and climatology, medicine and economics, and biology and manufacturing, notably through the relations between land, food and population. From the grand nineteenth-century transformations of matter to systems ecology, the circulation of molecules through organic and inorganic compartments has posed the problem of maintaining identity in the face of flux and highlights the seductive ability of cyclic schemes to imply closure where no original state was in fact restored. More concerted attention to cycles and circulation will enrich analyses of the power of metaphors to naturalize understandings of life and their shaping by practical interests and political imaginations. (shrink)