BackgroundSubjective cognitive decline, non-amnestic mild cognitive impairment, and amnestic mild cognitive impairment are regarded to be at high risk of converting to Alzheimer’s disease. Amplitude of low-frequency fluctuations can reflect functional deterioration while diffusion tensor imaging is capable of detecting white matter integrity. Our study aimed to investigate the structural and functional alterations to further reveal convergence and divergence among SCD, naMCI, and aMCI and how these contribute to cognitive deterioration.MethodsWe analyzed ALFF under slow-4 and slow-5 bands and white matter (...) fiber integrity among normal controls, SCD, naMCI, and aMCI groups. Correlation analyses were further utilized among paired DTI alteration, ALFF deterioration, and cognitive decline.ResultsFor ALFF calculation, ascended ALFF values were detected in the lingual gyrus and superior frontal gyrus within SCD and naMCI patients, respectively. Descended ALFF values were presented mainly in the LING, SFG, middle frontal gyrus, and precuneus in aMCI patients compared to CN, SCD, and naMCI groups. For DTI analyses, white matter alterations were detected within the uncinate fasciculus in aMCI patients and within the superior longitudinal fasciculus in naMCI patients. SCD patients presented alterations in both fasciculi. Correlation analyses revealed that the majority of these structural and functional alterations were associated with complicated cognitive decline. Besides, UF alterations were correlated with ALFF deterioration in the SFG within aMCI patients.ConclusionsSCD shares structurally and functionally deteriorative characteristics with aMCI and naMCI, and tends to convert to either of them. Furthermore, abnormalities in white matter fibers may be the structural basis of abnormal brain activation in preclinical AD stages. Combined together, it suggests that structural and functional integration may characterize the preclinical AD progression. (shrink)

本书以现实生活中的失礼行为为逻辑起点，针对学术界关于船山遵礼思想研究不足的现状，将文献资料与文化诠释相结合，哲学形上的构思与道德形下的建构相结合，试图以遵礼之气、遵礼之理、遵礼德性、遵礼原则、遵礼策略 、遵礼旨归为逻辑线索，建构起船山遵礼之道完整的逻辑体系。.

本书收录了中国哲学史大家陈来先生近年来关于新儒家一系列研究文章，从对“哲学”概念的理解谈起，详细讨论了20世纪中国哲学方面具有创造性的新儒家代表人物如熊十力、马一浮、梁漱溟、冯友兰等学者对儒学的创新和 发明。.

本书主要内容包括:超越西方哲学传统;反基础主义纲领;心理学唯名论;行为主义知识论;没有世界的真理观;后哲学文化;无本体论的伦理学等.

Ben shu li zu yu si xiang zheng zhi jiao yu de xue ke shi jiao, ba xian Qin ru jia jiao hua si xiang shi wei yi ge guo cheng he xi tong, jiang yi ge xiang dui wan zheng de, xi tong de xian Qin ru jia "jiao hua" si xiang li ti shi de cheng xian chu lai; bing li zu yu dang dai she hui de xian dai xing jiao hua kun jing wen ti, ji ji (...) cong xian Qin ru jia jiao hua si xiang zhe yi "chuan tong" zhong xun qiu jie jue zhi dao, li tu chan fa xian Qin ru jia jiao hua si xiang de dang dai zhuan hua wen ti. (shrink)

全书共分为四部分,主要内容包括第一部分文学理论研究;第二部分中国文学与日本文学研究;第三部分日本经典作家作品研究举要;第四部分中日学者对话.

本书主要内容包括:史料困境的突破与儒家系谱的重建;郭店竹简《性自命出》篇初探;竹帛《五行》为子思、孟子所作论;竹简《五行》分经解论:《五行》章句简注;竹简《五行》与子思思想研究等.

本书的内容, 是属于中国哲学思想史上的"道学"与"心学"的考论研究, 故最初拟命名为"道学与心学". 此一主题, 如果用日本学界习用的说法, 也可名为"朱子学与阳明学". 考虑到此种题目的著述所在多有, 故定今名, 以示区别.

先秦时期是"礼崩乐坏"的社会动乱时期, 先秦儒家敏锐地把握了社会动乱的根源所在等级秩序的破坏; 他们提出了解决这一问题的最佳方案--"分", 即对人群进行等级的区分与辨别, 确立一种以等级为特征的社会秩序; 秩序建构是一个永恒的治世主题; 在当下的和谐社会中, 我们可以借鉴儒家的智慧, 结合中国当代的现实, 深入思考秩序、伦理与和谐的内在关系, 从中寻求新的解答.

本书收录了的文章以中国历史、哲学、文学著作中的名言为引子, 结合现实生活, 并以个人的生活经验和哲学体悟相结合的方式, 阐述作者本人的哲学观点.